NL2022753A - Accommodating intraocular lens combination comprising a variable lens and a variable sulcal insert - Google Patents

Abstract

The invention relates to an intraocular lens combination to be implanted at the sulcal plane of the eye with the combination comprising at least one variable lens of variable power and at least one variable sulcal implant adapted to provide a separation, a barrier, between any component of the lens and the iris of the eye.

Description

Patent center

The Netherlands

Θ 2022753 (2?) Application number: 2022753 © Application submitted: March 18, 2019

A PATENT APPLICATION @ Int. Cl .:

A61F 2/16 (2019.01)

(30) Priority: (71) Applicant (s): March 19, 2018 NL 2020613 AKKOLENS INTERNATIONAL B.V. in Breda. (4?) Application registered: (72) Inventor (s): September 30, 2019 Michiel Christiaan Rombach in Breda. Aleksey Nikolaevich Simonov in Breda. (43) Application published: Willem Pieter van Lawick in Breda. October 1, 2019 (74) Agent: ir. H.Th. van den Heuvel et al. in 's-Hertogenbosch.

© Accommodating intraocular lens combination including a variable lens and a variable sulcal insert © The invention relates to an intraocular lens combination to be implanted at the sulcal plane of the eye with the combination including at least one variable lens or variable power and at least one variable sulcal implant adapted to provide a separation, a barrier, between any component of the lens and the iris of the eye.

NL A 2022753

This publication corresponds to the documents originally submitted.

Accommodating intraocular lens combination including a variable lens and a variable sulcal insert

The invention relates to an intraocular lens combination to be implanted at the sulcal plane of the eye with the combination including at least one variable lens or variable power and at least one variable sulcal implant adapted to provide a separation, a barrier, between any component or the lens and the iris of the eye.

Restoring vision of an aphakic eye, meaning: an eye with no lens, the eye becoming aphakic following removal of the natural lens of the eye, which is a common surgical procedure generally due to a cataract of the lens.

The eye is then implanted with a plastic lens which artificial restores sharp vision at, generally, only one plane, generally focused only 'at far', by a 'monofocal lens', or, alternatively, restores sharp vision at multiple distances simultaneously, generally at two or three distances, by implantation or multifocal lens.

However, the 'golden grail' in ophthalmology is restoration of 'true accommodation' by an implanted artificial lens, meaning: an artificial lens providing the eye with sharp vision all distances, a sharp vision graduating seamlessly from far to 'reading' distances, as does the natural lens in a healthy young eye.

This document, the present document, discloses an accommodating intraocular lens combination, henceforth: 'combination', with the combination including at least one variable optical lens, also: 'lens' and at least one with a sulcal insert, also: 'insert' which insert can be a sulcal disc, also: 'disc', or, alternatively, a sulcal ring, also: 'ring', with the combination to be positioned at the sulcal plane, behind the iris, with the combination adapted to replace the natural lens of the eye to restore refraction and accommodation of the eye.

The optics of the lens provide firstly accommodation, meaning: providing variable defocus aberration to provide sharp vision over a range of distances aberrations of the eye, but the lens can also, additionally, provide correction or at least one additional other order variable aberration, for example, spherical variable aberration, if such correction is required.

The lens included in the combination comprises at least two optical elements fitted, each, with at least one free-form, meaning: not rotational symmetrical, optical surface with at least one element adapted to translate in a direction largely perpendicular to the optical axis with the free-form surfaces providing a variable power or at least one optical aberration, generally the 2 ^nd order defocus aberration, with the degree of variable power depending on the degree of translation.

The translation of at least one of the optical elements is generally a shift, meaning: a sliding translation perpendicular to the optical axis, or, alternatively, a rotation in a plane perpendicular to the optical axis, or, alternatively, a wedging of the optical elements, or, alternatively, any other translation, or alternatively, any combination of any movements movement in a plane largely perpendicular to the optical axis. Such accommodating intraocular lenses are now well known, for example by prior art, including but not restricted to these documents: US2015342728, US2014336757, NL2012133, WO2014058315, US2012323321 and US2012310341.

The combination comprises at least one translation haptic, meaning: a mechanical component of the lens adapted to provide translation or at least one optical element by transfer of movement or at least one component of the eye to at least one of the optical elements, or, alternatively, the combination construction comprises at least one haptic adapted to provide a combination of positioning and translation. The at least one haptic is coupled to a natural component of the eye which component is generally, but not restricted hereto, the ciliary mass, the capsular bag or the capsular zonulae of the eye, or, alternatively, at least one haptic can be connected to any artificial intraocular mechanical driver, for example a MEMS.

The combination also includes an insert, which insert can include a central hole, to be positioned at the sulcal plane of the eye, with the insert adapted to provide a separation, a barrier, between any component of the lens, for example the anchors, meaning: the haptics, and the posterior surface of the iris of the eye. Such insert protects the iris from contact with any moving components of the lens and thus prevent release or pigment from the iris. The insert can be manufactured or any material, can be manufactured from the same material as the lens, can be manufactured or opaque material, or, alternatively, can be manufactured or transparent material. Additionally, the insert can also include any components adapted to provide directional guidance for translation or at least one of the elements of the lens.

The insert can be circular, meaning: round, or any diameter, and can be fitted with a central hole or diameter, preferably at least a diameter which is the maximum diameter of the iris, which is around 6mm, as not to interfere with the optics of the eye.

Alternatively, the insert can be of any shape, for example an oval insert which shape more conformed to the natural shape of the sulcus, which oval shape can be manufactured accordingly for a specific eye, meaning: a customized ring design.

Also, the desired shape of the hole can be determined before surgery customized, for example, an oval hole with the insert to be implanted at a specific angle, to be determined before surgery, with the shape of the hole adapted to provide correction or fixed undesired aberrations of the eye, for example coma.

Furthermore, the lens can be tapered, meaning: the posterior section of the lens is or a narrower diameter compared to the anterior section, such that the posterior section of the lens is fit in a capsulorhexis in the posterior section of the capsular bag of the eye with capsulorhexis applied during implantation surgery by any means or, alternatively, post surgery by YAG laser or by femtosecond laser.

Figure 1: An insert with (1) in this example, an opaque insert / ring, with (2) an oval hole, to correct, for an existing coma of the eye. Figure 2: an oblique view of the same ring as in Figure 1, with (2a) the ring, and (2b) guiding directional rings and, (2c) the oval hole. Figure 3: (3) the cornea of the eye, (3a) the anterior chamber of the eye, (4) the iris of the eye, (4a) the pigment layer of the eye, (4b) the ciliary mass of the eye with the contracting, accommodating, ciliary muscle filaments, (5) a 'ring', as in Fig.1, (6) the ciliary zonulae of the eye, (7) the anterior surface of the anterior element of the lens, (8 ) the free-form surfaces affecting accommodation, (9) the zonulae connecting the capsular bag to the ciliary mass, (10) the lens of fixed power which corrects the refraction of the aphakic eye, (11) the remnants of the exterior posterior capsular bag after posterior capsulorhexis, and (12) the anterior of the vitreous of the eye.

So, in summary: This document, the present document, discloses with an intraocular lens combination, also: 'combination', adapted to be implanted on the sulcal plane of the eye with the combination including at least one optical lens, also: lens', which has an optical axis, which lens comprises at least two optical elements fitted, each, with least one free-form optical surface with at least one element adapted to translate in a direction largely perpendicular to the optical axis with the free-form surfaces adapted to provide a lens of variable optical power with the degree of variable power depending on the degree of relative translation of the optical elements with the combination also including a sulcal insert to be positioned in the sulcal plane or the eye with the insert adapted to provide a separation, a barrier, between any component of the lens and the iris of the eye, with the insert a continuous disc, or, alternatively, with the insert is ring, a 'ring' meaning: ad isc including a central hole, with the insert manufactured or any material, which can be the same material as is the lens, or, alternatively, the insert is manufactured or any opaque material, or, alternatively, any transparent material, with the insert can also includes at least one component adapted to provide directional guidance for translation or at least one of the elements of the lens, with the insert being a continuous disc or any diameter or shape, or, alternatively, with the insert including a central hole or any diameter and of any shape, a slim 'donut', with the insert including a hole or any size or shape with the dimensions of the hole can be determined prior to surgery such that the dimensions can be customized according to the requirements of the particular eye into which the insert is implanted, with the insert in combination with a lens lens tapered such that the posterior section of the lens is adapted to fit in, fit through, a capsulorhexis in the posterior section of the capsular bag of the eye.

Claims (13)

Conclusions An intraocular lens combination, also: "combination", adapted to be implanted at the sulcal plane of the eye, the combination comprising at least one optical lens, also: "lens", which has an optical axis, and which lens has at least comprises two optical elements, each fitting with at least one shape-free optical surface with at least one element adapted to move in a direction substantially perpendicular to the optical axis, the shape-free surfaces being adapted to provide a lens with variable optical power wherein the degree of variable force depends on the degree of relative displacement of the optical elements, characterized in that the combination also comprises a sulcal insert that is to be positioned in the sulcal plane of the eye with the insert adapted to prevent a secretion or barrier differences between each component of the lens and the iris of the eye. 2. Combination according to claim 1, characterized in that the sulcal insert is adapted to be placed between the lens and the iris. Combination according to claim 1 or 2, characterized in that the sulcal insert is connected to the lens or the haptic parts of the lens. Combination according to claim 1,2 or 3, characterized in that the insert is a continuous disc. Combination according to any of claims 1-4, characterized in that the insert is a ring, in the sense of a disc comprising a central hole. Combination according to one of claims 1 to 5, characterized in that the insert is made of the same material as the lens. Combination according to one of claims 1 to 6, characterized in that the insert is made of an opaque material. Combination according to one of claims 1 to 6, characterized in that the insert is made of a transparent material. 9. Combination as claimed in any of the claims 1-8, characterized in that the insert also comprises at least one component which is adapted to provide a directional guide for displacing at least one of the elements of the lens. An insert that is part of a combination according to any one of claims 1 to 9, characterized in that the insert is a continuous disc. An insert that is part of a combination according to any one of claims 1 to 9, characterized in that the insert is a ring which includes a central hole. The insert according to claim 11, characterized in that the shape and dimensions of the hole are determined prior to surgery so that the dimensions are adjusted according to the requirements of the eye in which the insert is implanted. A combination according to claim 1, characterized in that the lens is tapered from front to rear, such that the rear of the lens is adapted to fit into or through a capsulorhexis in the posterior section of the capsular pocket of the eye . 1/1 Μ Μ 2c 2b