NL2022203B1 - Accommodative combination to position a lens in the sulcus of the human eye - Google Patents

Accommodative combination to position a lens in the sulcus of the human eye Download PDF

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NL2022203B1
NL2022203B1 NL2022203A NL2022203A NL2022203B1 NL 2022203 B1 NL2022203 B1 NL 2022203B1 NL 2022203 A NL2022203 A NL 2022203A NL 2022203 A NL2022203 A NL 2022203A NL 2022203 B1 NL2022203 B1 NL 2022203B1
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eye
combination
lens
accommodating
optical
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NL2022203A
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Dutch (nl)
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NL2022203A (en
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Christiaan Rombach Michiel
Nikolaevich Simonov Aleksey
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Akkolens Int B V
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Abstract

The present document discloses an accommodative, intraocular, combination to be implanted in the sulcus plane of the human eye with the combination comprising, 5 firstly, at least one accommodative lens, and, secondly, at least one supportive ring adapted to be implanted in the sulcus plane which supportive ring can be coupled to the sclera of the eye by anchors which anchors can penetrate the sclera of the eye.

Description

Accommodative combination to position a lens in the sulcus of the human eye The present document discloses an accommodative, intraocular, combination to be implanted in the sulcus plane of the human eye with the combination comprising, firstly, at least one accommodative lens, also: ‘lens’, having an optical axis with the lens comprising at least two optical elements of which at least one element is adapted to translate in at least one direction perpendicular to the optical axis with the optical surfaces of at least two elements adapted to vary at least one optical aberration of the lens with a degree of variation which is dependent on the degree of shift of the at least one of the optical elements, with the primary aberration to be varied being accommodation, meaning: variable defocus of the eye the combination also comprising, secondly, at least one supportive ring adapted to be implanted in the sulcus plane of the eye.
Such accommodating, translating, AIOLs are known from other documents, for example from NL2012133, NL201242, EP1871299, EP1932492, for designs of such AIOLs, and, for clinical results, Alio, in Am J Ophthamol 2016 Apr, 164: 37-48, with such documents not restricted hereto these documents referred to above.
These AlOLs are restricted to the concept which includes at least two cubic optical surfaces, meaning: Zernike third order surfaces, of which the basic, free-form, non- rotational symmetric, shapes are known from Alvarez US3305294, which provides the original concept for a variable lens, for laterally shifting optical elements, and Baker CA1252655, for derived fan-like rotational shifting optical elements. More precisely, in mathematics, these are all various variations on the basic formula according to Alvarez, t=A(xy2+x3/3, see US3305294 for details and notations). Such lenses can also provide, by movement of at least one of the optical elements, a variable extension of accommodation, and/or variable focus, and/or variable spherical aberration. Such movement can be achieved, but not restricted to, principles as disclosed in US2009062912 and WO2005084587, and the same concept, with various adaptations in, for example, US2014074233, WO2014058316, EP2765952, NL2012257278, US2010131955, US2010106245,
NL1029548 and references made therein and related documents, which principles have now been shown to function well in the human eye. The present document discloses an accommodative combination to be implanted in the sulcus plane of the human eye with the combination comprising, firstly, at least one accommodative lens , also: ‘lens’, having an optical axis with the lens comprising at least two optical elements of which at least one element is adapted to translate in at least one direction perpendicular to the optical axis with the optical surfaces of at least two elements adapted to vary at least one optical aberration of the lens with a degree of variation which is dependent on the degree of shift of the at least one of the optical elements, with the primary aberration to be varied being accommodation, meaning: variable defocus of the eye the combination also comprising, secondly, at least one supportive ring adapted to be implanted in the sulcus plane of the eye.
The supportive ring can be independent, meaning: not any component of the supportive ring is coupled to any component of the lens, or, alternatively, the supportive ring can be dependent, meaning: that at least one component of the supportive ring is firmly coupled to at least one component of the lens, with, for example, a pin-in hole connection. The supportive ring coupled to the sclera of the eye, for example, with the supportive ring firmly coupled to the sclera of the eye by anchors penetrating into the sclera of the eye.
The at least one haptic of the lens can be coupled to a natural component of the eye which component is the ciliary mass of the eye, or alternatively, the at least one haptic of the lens can be coupled to the capsular bag of the eye, or, alternatively, the at least one haptic of the lens can be coupled to a natural component of the eye which component is the zonula network of the eye, or, alternatively, the at least one haptic of the lens can be coupled to a natural component of the eye which component is the iris of the eye, or, alternatively, the at least one haptic is adapted to can translate at least one of the optical elements by liquid pressure generated in the posterior chamber of the eye, or, alternatively, the at least one haptic is coupled to a MEMS, meaning: micro-electro-mechanical system, which MEMS is adapted to provide movement of at least one optical element of the lens.
The accommodative combination can comprises at least one haptic adapted to urge the optical element back to a resting position, a position of decreased optical power, when the driving means are inactive.
Also, the optical elements can also comprise at least one optical surface adapted to correct for any fixed optical disorder of the eye, with the the fixed optical disorder can be presbyopia, meaning: ‘reading far-sightedness’. Also, the accommodative combination is adapted for implant in the human eye can correct for at least one variable optical disorder of the eye other than defocus.
The accommodative combination can correct for any variable disorder which is is a variable disorder generated by the lens, and, also, the accommodative combination can provide correction of any combination of at least one variable and at least one fixed disorder of the eye.
The accommodative combination, the supportive ring and the lens, can comprise at least one toric optical surface to provide correction of astigmatism of the eye with the lens and the supportive ring both comprising at least one coupling component to fix the rotational angle of the lens versus the rotational angle of the supportive ring.

Claims (18)

ConclusiesConclusions 1. Accommoderende combinatie, ingericht om te worden geïmplanteerd in het sulcusvlak van het menselijk oog, waarbij de combinatie ten eerste ten minste één accommoderende lens, ook ‘lens’, omvat, met een optische as, waarbij de lens ten minste twee optische elementen omvat waarvan ten minste één element is aangepast om te verschuiven in ten minste één richting loodrecht op de optische as, waarbij de optische oppervlakken van ten minste twee elementen zijn aangepast om ten minste één optische aberratie van de lens te variëren met een variatiegraad die afhankelijk is van de verschuivingsgraad van het ten minste ene van de optische elementen, waarbij de te variëren primaire aberratie accommodatie is, wat inhoudt: variabele defocus van het oog, met het kenmerk dat de combinatie tevens, ten tweede, ten minste één steunring omvat, die is aangepast om in het sulcusvlak van het oog te worden geïmplanteerd.An accommodating combination adapted to be implanted in the sulcus plane of the human eye, the combination comprising at least one accommodating lens, also 'lens', having an optical axis, the lens comprising at least two optical elements at least one element of which is adapted to shift in at least one direction perpendicular to the optical axis, the optical surfaces of at least two elements being adapted to vary at least one optical aberration of the lens with a degree of variation depending on the degree of shift of the at least one of the optical elements, the primary aberration to be varied being accommodation, which means: variable defocus of the eye, characterized in that the combination also includes, secondly, at least one support ring, which is adjusted to be implanted in the sulcus plane of the eye. 2. Accommoderende combinatie volgens conclusie 1, met het kenmerk dat de steunring onafhankelijk is, wat inhoudt: niet elke component van de steunring is aan een component van de lens gekoppeld.An accommodating combination according to claim 1, characterized in that the support ring is independent, which means that not every component of the support ring is coupled to a component of the lens. 3. Accommoderende combinatie volgens conclusie 1, met het kenmerk dat de steunring afhankelijk is, wat inhoudt: ten minste één component van de steunring is aan ten minste één component van de lens gekoppeld.An accommodating combination according to claim 1, characterized in that the support ring is dependent, which means: at least one component of the support ring is coupled to at least one component of the lens. A4. Accommoderende combinatie volgens conclusie 1-2, met het kenmerk dat de steunring aan het sclera van het oog is gekoppeld.A4. Accommodating combination according to claims 1-2, characterized in that the support ring is coupled to the sclera of the eye. 5. Accommoderende combinatie volgens conclusie 4, met het kenmerk dat de steunring stevig aan het sclera van het oog is gekoppeld door middel van verankeringen.An accommodating combination according to claim 4, characterized in that the support ring is firmly coupled to the sclera of the eye by means of anchors. 6. Accommoderende combinatie volgens een van de conclusies 1-5, met het kenmerk dat ten minste één haptic aan een natuurlijke component van het oog is gekoppeld, waarbij de component de ciliaire massa van het oog is.An accommodating combination according to any one of claims 1 to 5, characterized in that at least one haptic is linked to a natural component of the eye, the component being the ciliary mass of the eye. 7. Accommoderende combinatie volgens enige combinatie van de conclusies 1-5, met het kenmerk dat de ten minste ene haptic aan een natuurlijke component van het oog is gekoppeld, waarbij de component de kapselzak van het oog is.An accommodating combination according to any combination of claims 1 to 5, characterized in that the at least one haptic is coupled to a natural component of the eye, the component being the capsular bag of the eye. 5 8. Accommoderende combinatie volgens enige combinatie van de conclusies 1-5, met het kenmerk dat ten minste één haptic aan een natuurlijke component van het oog is gekoppeld, waarbij de component het zonula-netwerk van het oog is.8. Accommodating combination according to any combination of claims 1-5, characterized in that at least one haptic is linked to a natural component of the eye, the component being the zonula network of the eye. 9. Accommoderende combinatie volgens enige combinatie van de conclusies 1-5, met het kenmerk dat ten minste één haptic aan een natuurlijke component van het oog is gekoppeld, waarbij de component de iris van het oog is.An accommodating combination according to any combination of claims 1 to 5, characterized in that at least one haptic is linked to a natural component of the eye, the component being the iris of the eye. 10. Accommoderende combinatie volgens enige combinatie van de conclusies 1-5, met het kenmerk dat ten minste één haptic is aangepast om ten minste een van de optische elementen te verschuiven door middel van in de achterste kamer van het oog gegenereerde vloeistofdruk.An accommodating combination according to any combination of claims 1 to 5, characterized in that at least one haptic is adapted to shift at least one of the optical elements by means of fluid pressure generated in the posterior chamber of the eye. 11. Accommoderende combinatie volgens enige combinatie van de conclusies 1-6, met het kenmerk dat ten minste één haptic is gekoppeld aan een MEMS, wat inhoudt: micro-elektromechanisch systeem, waarbij het MEMS is aangepast om beweging van ten minste één optisch element van de lens te verschaffen.An accommodating combination according to any combination of claims 1 to 6, characterized in that at least one haptic is coupled to a MEMS, which means: micro-electromechanical system, wherein the MEMS is adapted to allow movement of at least one optical element of the the lens. 12. Accommoderende combinatie volgens een van de voorgaande conclusies, met het kenmerk dat de accommoderende combinatie ten minste één haptic omvat, die is aangepast om het optische element terug te dringen naar een rustpositie, een positie van verminderde optische sterkte, wanneer de aandrijfmiddelen inactief zijn.An accommodating combination according to any one of the preceding claims, characterized in that the accommodating combination comprises at least one haptic, which is adapted to urge the optical element back to a rest position, a position of reduced optical power, when the driving means are inactive. . 13. Accommoderende combinatie volgens enige combinatie van de voorgaande conclusies, met het kenmerk dat de optische elementen tevens ten minste één optisch oppervlak omvatten, dat is aangepast om een gefixeerde optische stoornis van het oog te corrigeren.An accommodating combination according to any combination of the preceding claims, characterized in that the optical elements also comprise at least one optical surface adapted to correct a fixed optical disorder of the eye. 14. Accommoderende combinatie volgens enige combinatie van de voorgaande conclusies, met het kenmerk dat de gefixeerde optische stoornis presbyopie is, wat inhoudt: ‘verziendheid’.An accommodating combination according to any combination of the preceding claims, characterized in that the fixed optical disorder is presbyopia, meaning "farsightedness". 15. Accommoderende combinatie volgens enige combinatie van de voorgaande conclusies, met het kenmerk dat de accommoderende combinatie is aangepast voor implantatie in het menselijk oog om ten minste één variabele optische stoornis van het oog anders dan defocus te corrigeren.An accommodating combination according to any combination of the preceding claims, characterized in that the accommodating combination is adapted for implantation in the human eye to correct at least one variable optical disorder of the eye other than defocus. 16. Accommoderende combinatie volgens conclusie 15, met het kenmerk dat de variabele stoornis een door de lens gegenereerde variabele stoornis is.An accommodating combination according to claim 15, characterized in that the variable disorder is a lens-generated variable disorder. 17. Accommoderende combinatie volgens enige combinatie van conclusies 1- 16, met het kenmerk dat de lens is aangepast om correctie van enige combinatie van ten minste één variabele en ten minste één gefixeerde stoornis van het oog te verschaffen.An accommodating combination according to any combination of claims 1-16, characterized in that the lens is adapted to provide correction of any combination of at least one variable and at least one fixed disorder of the eye. 18. Accommoderende intraoculaire accommoderende combinatie volgens enige combinatie van voorgaande conclusies met het kenmerk dat de steunring en de lens, waarbij de lens ten minste één torisch optisch oppervlak omvat dat is aangepast om correctie van astigmatisme van het oog te verschaffen, waarbij de steunring en de lens beide ten minste één koppelingscomponent omvatten, die is aangepast om de draaihoek van de lens ten opzichte van de draaihoek van de steunring te fixeren.An accommodative intraocular accommodative combination according to any combination of the preceding claims characterized in that the support ring and the lens, the lens comprising at least one toric optical surface adapted to provide correction of astigmatism of the eye, wherein the support ring and the lens lens both include at least one coupling component that is adapted to fix the angle of rotation of the lens relative to the angle of rotation of the support ring.
NL2022203A 2018-01-09 2018-12-13 Accommodative combination to position a lens in the sulcus of the human eye NL2022203B1 (en)

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