NL180479B - METHOD FOR THE PREPARATION OR MANUFACTURE OF MEDICINAL PRODUCTS WITH ANTI-INFLAMMATORY AND CORTICOID ACTIVITY, MEDICINES FORMED AND METHOD FOR THE PREPARATION OF 1,4-PREGNADADIA COMPOUNDS SUITABLE FOR USE AS THE PRODUCT IN ITS PROPERTIES. - Google Patents

METHOD FOR THE PREPARATION OR MANUFACTURE OF MEDICINAL PRODUCTS WITH ANTI-INFLAMMATORY AND CORTICOID ACTIVITY, MEDICINES FORMED AND METHOD FOR THE PREPARATION OF 1,4-PREGNADADIA COMPOUNDS SUITABLE FOR USE AS THE PRODUCT IN ITS PROPERTIES.

Info

Publication number
NL180479B
NL180479B NLAANVRAGE7714056,A NL7714056A NL180479B NL 180479 B NL180479 B NL 180479B NL 7714056 A NL7714056 A NL 7714056A NL 180479 B NL180479 B NL 180479B
Authority
NL
Netherlands
Prior art keywords
preparation
pregnadadia
inflammatory
manufacture
properties
Prior art date
Application number
NLAANVRAGE7714056,A
Other languages
Dutch (nl)
Other versions
NL7714056A (en
NL180479C (en
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/753,257 external-priority patent/US4076708A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of NL7714056A publication Critical patent/NL7714056A/en
Publication of NL180479B publication Critical patent/NL180479B/en
Application granted granted Critical
Publication of NL180479C publication Critical patent/NL180479C/en

Links

Classifications

    • EFIXED CONSTRUCTIONS
    • E04BUILDING
    • E04GSCAFFOLDING; FORMS; SHUTTERING; BUILDING IMPLEMENTS OR AIDS, OR THEIR USE; HANDLING BUILDING MATERIALS ON THE SITE; REPAIRING, BREAKING-UP OR OTHER WORK ON EXISTING BUILDINGS
    • E04G11/00Forms, shutterings, or falsework for making walls, floors, ceilings, or roofs
    • E04G11/06Forms, shutterings, or falsework for making walls, floors, ceilings, or roofs for walls, e.g. curved end panels for wall shutterings; filler elements for wall shutterings; shutterings for vertical ducts
    • E04G11/20Movable forms; Movable forms for moulding cylindrical, conical or hyperbolical structures; Templates serving as forms for positioning blocks or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0084Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • EFIXED CONSTRUCTIONS
    • E04BUILDING
    • E04GSCAFFOLDING; FORMS; SHUTTERING; BUILDING IMPLEMENTS OR AIDS, OR THEIR USE; HANDLING BUILDING MATERIALS ON THE SITE; REPAIRING, BREAKING-UP OR OTHER WORK ON EXISTING BUILDINGS
    • E04G17/00Connecting or other auxiliary members for forms, falsework structures, or shutterings
    • E04G17/14Bracing or strutting arrangements for formwalls; Devices for aligning forms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Architecture (AREA)
  • Engineering & Computer Science (AREA)
  • Civil Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Structural Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
NLAANVRAGE7714056,A 1976-12-22 1977-12-19 METHOD FOR THE PREPARATION OR MANUFACTURE OF MEDICINAL PRODUCTS WITH ANTI-INFLAMMATORY AND CORTICOID ACTIVITY, MEDICINES FORMED AND METHOD FOR THE PREPARATION OF 1,4-PREGNADADIA COMPOUNDS SUITABLE FOR USE AS THE PRODUCT IN ITS PROPERTIES. NL180479C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75325676A 1976-12-22 1976-12-22
US05/753,257 US4076708A (en) 1976-12-22 1976-12-22 Process for the preparation of 7α-halogeno-3-oxo-4-dehydro steroids and novel 7α-halogeno derivatives produced thereby

Publications (3)

Publication Number Publication Date
NL7714056A NL7714056A (en) 1978-06-26
NL180479B true NL180479B (en) 1986-10-01
NL180479C NL180479C (en) 1987-03-02

Family

ID=27115720

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7714056,A NL180479C (en) 1976-12-22 1977-12-19 METHOD FOR THE PREPARATION OR MANUFACTURE OF MEDICINAL PRODUCTS WITH ANTI-INFLAMMATORY AND CORTICOID ACTIVITY, MEDICINES FORMED AND METHOD FOR THE PREPARATION OF 1,4-PREGNADADIA COMPOUNDS SUITABLE FOR USE AS THE PRODUCT IN ITS PROPERTIES.

Country Status (20)

Country Link
JP (1) JPS604198B2 (en)
AR (1) AR226806A1 (en)
AT (2) AT373269B (en)
BE (1) BE862089A (en)
DE (1) DE2756550C2 (en)
DK (1) DK153494C (en)
FI (1) FI63947C (en)
FR (1) FR2384793A1 (en)
GB (1) GB1575983A (en)
HK (1) HK584A (en)
HU (1) HU179784B (en)
IE (1) IE45950B1 (en)
IL (1) IL53636A (en)
MY (1) MY8500082A (en)
NL (1) NL180479C (en)
NO (1) NO151826C (en)
NZ (1) NZ186031A (en)
PT (1) PT67432B (en)
SE (1) SE429865B (en)
SG (1) SG58683G (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109680036A (en) 2017-10-02 2019-04-26 爱科来株式会社 The measurement of glycated proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3429926A (en) * 1964-05-25 1969-02-25 Squibb & Sons Inc 7-halo and 6-halo,6-dehydro a-norprogesterones

Also Published As

Publication number Publication date
DK153494B (en) 1988-07-18
AR226806A1 (en) 1982-08-31
AT377566B (en) 1985-04-10
FI63947C (en) 1983-09-12
IL53636A0 (en) 1978-03-10
NO151826C (en) 1985-06-12
FI773825A (en) 1978-06-23
NL7714056A (en) 1978-06-26
NL180479C (en) 1987-03-02
SE7714538L (en) 1978-06-23
DK153494C (en) 1989-02-20
SE429865B (en) 1983-10-03
ATA575980A (en) 1982-04-15
SG58683G (en) 1985-01-11
DE2756550A1 (en) 1978-07-06
DK569977A (en) 1978-09-28
FR2384793A1 (en) 1978-10-20
IL53636A (en) 1983-05-15
JPS5379850A (en) 1978-07-14
PT67432A (en) 1978-01-01
MY8500082A (en) 1985-12-31
HK584A (en) 1984-01-13
JPS604198B2 (en) 1985-02-01
HU179784B (en) 1982-12-28
AT373269B (en) 1984-01-10
FR2384793B1 (en) 1981-11-13
BE862089A (en) 1978-06-20
IE45950L (en) 1978-06-22
DE2756550C2 (en) 1986-10-16
NO774359L (en) 1978-06-23
FI63947B (en) 1983-05-31
NO151826B (en) 1985-03-04
PT67432B (en) 1979-05-23
ATA909477A (en) 1983-05-15
GB1575983A (en) 1980-10-01
IE45950B1 (en) 1983-01-12
NZ186031A (en) 1984-07-31

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