NL176458B - PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND PROCESS FOR PREPARING ACTIVE SUBSTANCES SUITABLE. - Google Patents

PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND PROCESS FOR PREPARING ACTIVE SUBSTANCES SUITABLE.

Info

Publication number
NL176458B
NL176458B NLAANVRAGE7212915,A NL7212915A NL176458B NL 176458 B NL176458 B NL 176458B NL 7212915 A NL7212915 A NL 7212915A NL 176458 B NL176458 B NL 176458B
Authority
NL
Netherlands
Prior art keywords
preparing
active substances
pharmaceutical preparation
substances suitable
preparing active
Prior art date
Application number
NLAANVRAGE7212915,A
Other languages
Dutch (nl)
Other versions
NL7212915A (en
NL176458C (en
Inventor
Willem Jacob Van Der Burg
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Priority to NLAANVRAGE7212915,A priority Critical patent/NL176458C/en
Priority to ZA737131*A priority patent/ZA737131B/en
Priority to IE1587/73A priority patent/IE38221B1/en
Priority to US396251A priority patent/US3892695A/en
Priority to AU60197/73A priority patent/AU472312B2/en
Priority to GB4331873A priority patent/GB1445765A/en
Priority to DK507673AA priority patent/DK140668B/en
Priority to CA181,312A priority patent/CA1019733A/en
Priority to FR7333768A priority patent/FR2199996B1/fr
Priority to AR250175A priority patent/AR203090A1/en
Priority to BE135926A priority patent/BE805178A/en
Priority to DE2347727A priority patent/DE2347727C2/en
Priority to FI2963/73A priority patent/FI54311C/en
Priority to CH1358173A priority patent/CH592094A5/xx
Priority to JP48106809A priority patent/JPS5912678B2/en
Priority to HUAO373A priority patent/HU167206B/hu
Priority to SE7312873A priority patent/SE407686B/en
Priority to ES418996A priority patent/ES418996A1/en
Publication of NL7212915A publication Critical patent/NL7212915A/xx
Publication of NL176458B publication Critical patent/NL176458B/en
Application granted granted Critical
Publication of NL176458C publication Critical patent/NL176458C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NLAANVRAGE7212915,A 1972-09-23 1972-09-23 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND PROCESS FOR PREPARING ACTIVE SUBSTANCES SUITABLE. NL176458C (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
NLAANVRAGE7212915,A NL176458C (en) 1972-09-23 1972-09-23 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND PROCESS FOR PREPARING ACTIVE SUBSTANCES SUITABLE.
ZA737131*A ZA737131B (en) 1972-09-23 1973-09-06 Novel pyrimidino derivatives
IE1587/73A IE38221B1 (en) 1972-09-23 1973-09-06 Novel tetracyclic pyramidines
US396251A US3892695A (en) 1972-09-23 1973-09-07 Pyrimidino-dibenzo-azepine,-oxazepine,-thiazepine and diazepine derivatives
AU60197/73A AU472312B2 (en) 1972-09-23 1973-09-11 Novel pyrimidino derivatives
GB4331873A GB1445765A (en) 1972-09-23 1973-09-14 Phenoxy-substituted malonic acid derivatives their prepration and pharmaceutical compositions containing them
DK507673AA DK140668B (en) 1972-09-23 1973-09-17 Analogous process for the preparation of condensed pyrimine derivatives.
CA181,312A CA1019733A (en) 1972-09-23 1973-09-18 Pyrimidino-dibenzo-azepine, dibenzo-oxazepine, -thiazepine and -diazepine derivatives
FR7333768A FR2199996B1 (en) 1972-09-23 1973-09-20
AR250175A AR203090A1 (en) 1972-09-23 1973-09-20 PROCEDURE FOR THE PREPARATION OF HEXAHYDRO-PYRIMIDINE-DIBENZO-AZEPINE DERIVATIVES
DE2347727A DE2347727C2 (en) 1972-09-23 1973-09-21 Dibenzo-pyrimido-azepines, oxazepines and diazepines
FI2963/73A FI54311C (en) 1972-09-23 1973-09-21 PROCEDURE FOR THE FRAMSTATION OF AV PYRIMIDINOBENSO-OXAZEPINER -TIAZEPINER -DIAZEPINER OCH -AZEPINER WITH INVERKAN PAO CENTRALNERVSYSTEMET
CH1358173A CH592094A5 (en) 1972-09-23 1973-09-21
JP48106809A JPS5912678B2 (en) 1972-09-23 1973-09-21 Method for producing novel pyrimidine derivatives
BE135926A BE805178A (en) 1972-09-23 1973-09-21 NEW PYRIMIDINE DERIVATIVES
HUAO373A HU167206B (en) 1972-09-23 1973-09-21
SE7312873A SE407686B (en) 1972-09-23 1973-09-21 ANALOGICAL PROCEDURE FOR PREPARING CONDENSED PYRIMIDINE DERIVATIVES
ES418996A ES418996A1 (en) 1972-09-23 1973-09-22 Pyrimidino-dibenzo-azepine,-oxazepine,-thiazepine and diazepine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE7212915,A NL176458C (en) 1972-09-23 1972-09-23 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND PROCESS FOR PREPARING ACTIVE SUBSTANCES SUITABLE.

Publications (3)

Publication Number Publication Date
NL7212915A NL7212915A (en) 1974-03-26
NL176458B true NL176458B (en) 1984-11-16
NL176458C NL176458C (en) 1985-04-16

Family

ID=19816997

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7212915,A NL176458C (en) 1972-09-23 1972-09-23 PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION AND PROCESS FOR PREPARING ACTIVE SUBSTANCES SUITABLE.

Country Status (18)

Country Link
US (1) US3892695A (en)
JP (1) JPS5912678B2 (en)
AR (1) AR203090A1 (en)
AU (1) AU472312B2 (en)
BE (1) BE805178A (en)
CA (1) CA1019733A (en)
CH (1) CH592094A5 (en)
DE (1) DE2347727C2 (en)
DK (1) DK140668B (en)
ES (1) ES418996A1 (en)
FI (1) FI54311C (en)
FR (1) FR2199996B1 (en)
GB (1) GB1445765A (en)
HU (1) HU167206B (en)
IE (1) IE38221B1 (en)
NL (1) NL176458C (en)
SE (1) SE407686B (en)
ZA (1) ZA737131B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL179906C (en) * 1974-02-09 1986-12-01 Akzo Nv PROCESS FOR PREPARING 1,2,3,4,10,14B-HEXAHYDRODIBENZO (C, F) PYRAZINO (1,2-A) AZEPINE DERIVATIVES.
US4217452A (en) * 1974-02-09 1980-08-12 Akzona Incorporated Synthesis for the preparation of tetracyclic compounds
NL7414038A (en) * 1974-10-28 1976-05-03 Akzo Nv NEW TETRACYCLIC PYRROLIDINO DERIVATIVES.
GB1472382A (en) * 1975-01-16 1977-05-04 Wyeth John & Brother Ltd Dibenzopyrimidoazepines
NL7610942A (en) * 1976-10-02 1978-04-04 Akzo Nv PROCESS FOR PREPARING 1,4-DIAZEPINE DERIVATIVES.
NL7809726A (en) * 1978-09-26 1980-03-28 Akzo Nv NEW TETRACYCLIC CONNECTIONS.
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
CH678623A5 (en) * 1989-05-17 1991-10-15 Sochinaz Societe Chimique De V Prepn. of di:benzo pyrazino azepine(s)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154511B (en) * 1967-07-07 1977-09-15 Organon Nv PROCESS FOR PREPARING PIPERAZINE DERIVATIVES, PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION CONTAINING SUCH A COMPOUND AND MOLDS PREPARED ACCORDING TO THIS PROCEDURE.
US3470181A (en) * 1967-10-23 1969-09-30 American Home Prod Fused 2-pyrimidinepropionic acid compounds,related compounds,and the process for their preparation

Also Published As

Publication number Publication date
DK140668C (en) 1980-03-24
FR2199996B1 (en) 1977-09-09
GB1445765A (en) 1976-08-11
DE2347727C2 (en) 1986-12-11
ES418996A1 (en) 1976-07-01
HU167206B (en) 1975-09-27
DK140668B (en) 1979-10-22
CH592094A5 (en) 1977-10-14
AU472312B2 (en) 1976-05-20
IE38221L (en) 1974-03-23
CA1019733A (en) 1977-10-25
DE2347727A1 (en) 1974-04-04
FI54311B (en) 1978-07-31
NL7212915A (en) 1974-03-26
FI54311C (en) 1978-11-10
ZA737131B (en) 1974-08-28
SE407686B (en) 1979-04-09
FR2199996A1 (en) 1974-04-19
AR203090A1 (en) 1975-08-14
IE38221B1 (en) 1978-01-18
JPS5912678B2 (en) 1984-03-24
NL176458C (en) 1985-04-16
BE805178A (en) 1974-03-21
AU6019773A (en) 1975-03-13
US3892695A (en) 1975-07-01
JPS4985098A (en) 1974-08-15

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Legal Events

Date Code Title Description
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee