NL130098C - - Google Patents

Info

Publication number
NL130098C
NL130098C NL130098DA NL130098C NL 130098 C NL130098 C NL 130098C NL 130098D A NL130098D A NL 130098DA NL 130098 C NL130098 C NL 130098C
Authority
NL
Netherlands
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of NL130098C publication Critical patent/NL130098C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NL130098D 1963-07-15 NL130098C (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB27990/63A GB1101424A (en) 1963-07-15 1963-07-15 Derivatives of 7-aminocephalosporanic acid
GB27989/63A GB1101423A (en) 1963-07-15 1963-07-15 Derivatives of 7-aminocephalosporanic acid
GB1474764 1964-04-09
GB1474864 1964-04-09

Publications (1)

Publication Number Publication Date
NL130098C true NL130098C (pt)

Family

ID=27448261

Family Applications (3)

Application Number Title Priority Date Filing Date
NL130098D NL130098C (pt) 1963-07-15
NL6408067A NL6408067A (pt) 1963-07-15 1964-07-15
NL6408066A NL6408066A (pt) 1963-07-15 1964-07-15

Family Applications After (2)

Application Number Title Priority Date Filing Date
NL6408067A NL6408067A (pt) 1963-07-15 1964-07-15
NL6408066A NL6408066A (pt) 1963-07-15 1964-07-15

Country Status (13)

Country Link
US (2) US3261832A (pt)
BE (2) BE650444A (pt)
BR (1) BR6460800D0 (pt)
CH (2) CH469022A (pt)
CS (1) CS166185B2 (pt)
DE (1) DE1445835B2 (pt)
DK (2) DK124334B (pt)
FR (2) FR1455030A (pt)
GB (2) GB1101424A (pt)
IL (2) IL21639A (pt)
NL (3) NL6408067A (pt)
NO (1) NO128157B (pt)
SE (1) SE335532B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3365449A (en) * 1964-07-23 1968-01-23 Fujisawa Pharmaceutical Co 7-(substituted thioacylamino) cephalosporanic acid and derivatives thereof
US3360515A (en) * 1964-07-24 1967-12-26 Fujisawa Pharmaceutical Co 7-(condensed n-containing heterocyclic carbonamido) cephalosporanic acid and derivatives thereof
US3479350A (en) * 1966-12-05 1969-11-18 Glaxo Lab Ltd Process for the manufacture of derivatives of cephalosporin c
GB1277415A (en) * 1968-06-14 1972-06-14 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3687948A (en) * 1970-11-23 1972-08-29 Bristol Myers Co 7-{8 D-(a-AMINO-a-PHENYLACETAMIDO){9 -3-(4-METHYL-1,3-OXAZOL-2-YLTHIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACID AND SALTS THEREOF
US4024135A (en) * 1976-03-05 1977-05-17 E. R. Squibb & Sons, Inc. (Carbamoyl)pyridino derivatives of ureidocephalosporins
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
JPS6027677B2 (ja) * 1978-07-06 1985-06-29 富山化学工業株式会社 7−置換又は非置換アミノ−3−置換チオメチルセフエムカルボン酸類の新規製造法
US4288590A (en) * 1980-02-14 1981-09-08 Bristol-Myers Company 7-[Dα-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-α-arylacetamido]-3-(N,N-dimethyl-aminomethylpyridinium) methyl-3-cephem-4-carboxylates
ZA825095B (en) * 1981-07-17 1983-05-25 Glaxo Group Ltd Cephalosporin compounds
EP2209474A4 (en) 2007-10-09 2013-07-24 Sopharmia Inc BROAD SPECTRUM BETA-LACTAMASE INHIBITORS
US20120329770A1 (en) * 2010-02-26 2012-12-27 Gary Igor Dmitrienko Cephalosporin derivatives useful as beta-lactamase inhibitors and compositions and methods of use thereof

Also Published As

Publication number Publication date
NL6408066A (pt) 1965-01-18
BE650445A (pt) 1965-01-11
FR1455030A (fr) 1966-04-01
IL21640A (en) 1968-04-25
BR6460800D0 (pt) 1973-08-02
BE650444A (pt) 1965-01-11
US3243435A (en) 1966-03-29
CH469022A (de) 1969-02-28
CS166185B2 (pt) 1976-01-29
DE1445835A1 (de) 1969-01-09
DE1445835B2 (de) 1976-04-22
SE335532B (pt) 1971-06-01
CH469739A (de) 1969-03-15
US3261832A (en) 1966-07-19
GB1101423A (en) 1968-01-31
GB1101424A (en) 1968-01-31
NO128157B (pt) 1973-10-08
NL6408067A (pt) 1965-01-18
DK124334B (da) 1972-10-09
FR4315M (pt) 1966-08-01
DK120544B (pt) 1971-06-14
DK120544C (da) 1971-11-08
IL21639A (en) 1968-04-25

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