MY195264A - Granules Containing Besifovir Dipivoxil or Pharmaceutically Acceptable Salt Thereof, Pharmaceutical Composition Comprising Granules, And Preparation Method Therefor - Google Patents
Granules Containing Besifovir Dipivoxil or Pharmaceutically Acceptable Salt Thereof, Pharmaceutical Composition Comprising Granules, And Preparation Method ThereforInfo
- Publication number
- MY195264A MY195264A MYPI2019004745A MYPI2019004745A MY195264A MY 195264 A MY195264 A MY 195264A MY PI2019004745 A MYPI2019004745 A MY PI2019004745A MY PI2019004745 A MYPI2019004745 A MY PI2019004745A MY 195264 A MY195264 A MY 195264A
- Authority
- MY
- Malaysia
- Prior art keywords
- granules
- besifovir
- dipivoxil
- preparation
- pharmaceutically acceptable
- Prior art date
Links
- 239000008187 granular material Substances 0.000 title abstract 4
- JLKJXDOWBVVABZ-UHFFFAOYSA-N [[1-[(2-aminopurin-9-yl)methyl]cyclopropyl]oxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate Chemical compound C1=NC2=CN=C(N)N=C2N1CC1(OCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)CC1 JLKJXDOWBVVABZ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 235000019658 bitter taste Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to: granules containing besifovir dipivoxil or a pharmaceutically acceptable salt thereof, and having a masked bitter taste and improved productivity; a pharmaceutical composition comprising the granules; and a preparation method therefor. (Figure 1)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020170028912A KR101899773B1 (en) | 2017-03-07 | 2017-03-07 | Granules comprising besifovir dipivoxil or pharmaceutical acceptable salts thereof, a pharmaceutical composition comprising the same and a method for preparing the same |
PCT/KR2018/002659 WO2018164458A1 (en) | 2017-03-07 | 2018-03-06 | Granules containing besifovir dipivoxil or pharmaceutically acceptable salt thereof, pharmaceutical composition comprising granules, and preparation method therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
MY195264A true MY195264A (en) | 2023-01-11 |
Family
ID=63448573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI2019004745A MY195264A (en) | 2017-03-07 | 2018-03-06 | Granules Containing Besifovir Dipivoxil or Pharmaceutically Acceptable Salt Thereof, Pharmaceutical Composition Comprising Granules, And Preparation Method Therefor |
Country Status (7)
Country | Link |
---|---|
KR (1) | KR101899773B1 (en) |
CN (1) | CN110582272A (en) |
MY (1) | MY195264A (en) |
PH (1) | PH12019501967A1 (en) |
SG (1) | SG11201907826YA (en) |
TW (1) | TWI786092B (en) |
WO (1) | WO2018164458A1 (en) |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL193682C (en) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Coated Cefuroxime Maxetil Composition. |
KR100676075B1 (en) * | 2005-02-17 | 2007-02-01 | 한국유나이티드제약 주식회사 | A Pellet Agent Containing Clarithromycin for oral suspension |
CL2008000070A1 (en) * | 2007-01-17 | 2008-07-25 | Lg Life Sciences Ltd | MALEIC ACID MONOSAL (3 - [({1 - [(2-AMINO-9H-PURIN-9-IL) METHYL] CICLOPROPIL} OXI) METHYL] -8,8-DIMETHYL-3,7-DIOXO-2,4 , 6-TRIOXA-3 LAMBDA 5-PHOSPHANON-1-IL-PIVALATE; PHARMACEUTICAL COMPOSITION THAT INCLUDES THE SUCH MONOSAL; AND USE FOR THE TREATMENT OF VIRUS H |
US20120093738A1 (en) * | 2009-06-11 | 2012-04-19 | Rubicon Research Private Limited | Taste-masked oral formulations of influenza antivirals |
MX2015016675A (en) * | 2013-06-04 | 2016-07-15 | Vyome Biosciences Pvt Ltd | Coated particles and compositions comprising same. |
JP2017526730A (en) | 2014-09-16 | 2017-09-14 | ギリアード サイエンシーズ, インコーポレイテッド | Solid form of Toll-like receptor modulator |
SI3321265T1 (en) | 2015-03-04 | 2020-07-31 | Gilead Sciences, Inc. | 4,6-diamino-pyrido(3,2-d)pyrimidine compounds and their utilisation as modulators of toll-like receptors |
KR20170132327A (en) * | 2015-04-07 | 2017-12-01 | 스프링 뱅크 파마슈티칼스, 인크. | Compositions and methods for the treatment of HBV infection |
-
2017
- 2017-03-07 KR KR1020170028912A patent/KR101899773B1/en active IP Right Grant
-
2018
- 2018-03-06 SG SG11201907826YA patent/SG11201907826YA/en unknown
- 2018-03-06 WO PCT/KR2018/002659 patent/WO2018164458A1/en active Application Filing
- 2018-03-06 TW TW107107345A patent/TWI786092B/en active
- 2018-03-06 MY MYPI2019004745A patent/MY195264A/en unknown
- 2018-03-06 CN CN201880016228.6A patent/CN110582272A/en active Pending
-
2019
- 2019-08-27 PH PH12019501967A patent/PH12019501967A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR101899773B1 (en) | 2018-09-18 |
KR20180102375A (en) | 2018-09-17 |
PH12019501967A1 (en) | 2020-06-15 |
SG11201907826YA (en) | 2019-09-27 |
TW201832759A (en) | 2018-09-16 |
CN110582272A (en) | 2019-12-17 |
WO2018164458A1 (en) | 2018-09-13 |
TWI786092B (en) | 2022-12-11 |
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