MY186726A - Anti-activin a antibodies and uses thereof - Google Patents

Anti-activin a antibodies and uses thereof

Info

Publication number
MY186726A
MY186726A MYPI2016700339A MYPI2016700339A MY186726A MY 186726 A MY186726 A MY 186726A MY PI2016700339 A MYPI2016700339 A MY PI2016700339A MY PI2016700339 A MYPI2016700339 A MY PI2016700339A MY 186726 A MY186726 A MY 186726A
Authority
MY
Malaysia
Prior art keywords
antibodies
activin
useful
treatment
diseases
Prior art date
Application number
MYPI2016700339A
Inventor
Gromada Jesper
Latres Esther
J Murphy Andrew
D Yancopoulos George
C Morton Lori
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Priority claimed from PCT/US2014/048957 external-priority patent/WO2015017576A1/en
Publication of MY186726A publication Critical patent/MY186726A/en

Links

Abstract

The present invention provides antibodies that bind to Activin A and methods of using the same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to Activin A with high affinity. The antibodies of the invention are useful for the treatment of diseases and disorders characterized by decreased muscle mass or strength, such as sarcopenia, cachexia, muscle injury, muscle wasting/at rophy, cancer, fibrosis, and weight loss. The antibodies of the invention are also useful in combination with GDF8 binding proteins for the treatment of diseases and disorders characterized by decreased muscle mass or strength. The antibodies of the invention are also useful for the prevention, treatment, or amelioration of disorders and diseases caused by, promoted by, exacerbated by, and/or aggravated by Activin A, such as renal fibrosis.
MYPI2016700339A 2013-07-30 2014-07-30 Anti-activin a antibodies and uses thereof MY186726A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361859926P 2013-07-30 2013-07-30
US201361864036P 2013-08-09 2013-08-09
US201361911834P 2013-12-04 2013-12-04
PCT/US2014/048957 WO2015017576A1 (en) 2013-07-30 2014-07-30 Anti-activin a antibodies and uses thereof

Publications (1)

Publication Number Publication Date
MY186726A true MY186726A (en) 2021-08-13

Family

ID=81329898

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2016700339A MY186726A (en) 2013-07-30 2014-07-30 Anti-activin a antibodies and uses thereof

Country Status (1)

Country Link
MY (1) MY186726A (en)

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