MY180272A - A monoclonal antibody inhibiting immunosuppressive functions of pathogens, antigen-binding fragment thereof, and hybridomas producing such antibody - Google Patents
A monoclonal antibody inhibiting immunosuppressive functions of pathogens, antigen-binding fragment thereof, and hybridomas producing such antibodyInfo
- Publication number
- MY180272A MY180272A MYPI2017701770A MYPI2017701770A MY180272A MY 180272 A MY180272 A MY 180272A MY PI2017701770 A MYPI2017701770 A MY PI2017701770A MY PI2017701770 A MYPI2017701770 A MY PI2017701770A MY 180272 A MY180272 A MY 180272A
- Authority
- MY
- Malaysia
- Prior art keywords
- antigen
- binding fragment
- antibody
- monoclonal antibody
- pathogens
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/121—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Helicobacter (Campylobacter) (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The present invention relates to a monoclonal antibody that inhibits immunosuppressive functions of pathogens, antigen-binding fragment thereof, and hybridomas producing such antibody. The monoclonal antibody or antigen-binding fragment thereof bind to a peptide consisting an amino acid sequence represented by MEKVGKDGVITVE (SEQ ID NO: 1). The present invention also discloses use of the invented monoclonal antibody or antigen-binding fragment thereof, and method of preparation for such hybridomas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/165,723 US10577409B2 (en) | 2016-05-26 | 2016-05-26 | Monoclonal antibody inhibiting immunosuppressive functions of pathogens, antigen-binding fragment thereof, and hybridomas producing such antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
MY180272A true MY180272A (en) | 2020-11-26 |
Family
ID=60421016
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI2017701770A MY180272A (en) | 2016-05-26 | 2017-05-17 | A monoclonal antibody inhibiting immunosuppressive functions of pathogens, antigen-binding fragment thereof, and hybridomas producing such antibody |
Country Status (13)
Country | Link |
---|---|
US (2) | US10577409B2 (en) |
JP (1) | JP6776033B2 (en) |
KR (1) | KR102241619B1 (en) |
AU (1) | AU2017203225B2 (en) |
BR (1) | BR102017010401A2 (en) |
CA (1) | CA2967597C (en) |
IL (1) | IL251997A0 (en) |
MX (1) | MX2017006603A (en) |
MY (1) | MY180272A (en) |
NZ (1) | NZ731906A (en) |
PH (1) | PH12017000140B1 (en) |
RU (1) | RU2751918C2 (en) |
SG (1) | SG10201704029WA (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3128526A1 (en) * | 2019-02-01 | 2020-08-06 | Board Of Regents, The University Of Texas System | Monoclonal antibodies against mhc-bound human dickkopf-1 peptides and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1262896B (en) | 1992-03-06 | 1996-07-22 | CONJUGATE COMPOUNDS FORMED FROM HEAT SHOCK PROTEIN (HSP) AND OLIGO-POLY-SACCHARIDES, THEIR USE FOR THE PRODUCTION OF VACCINES. | |
AR003125A1 (en) * | 1995-06-01 | 1998-07-08 | Astra Ab | BACTERIAL ANTIGENS FOR THE DIAGNOSIS OF INFECTIONS WITH HELICOBACTER PYLORI, A DNA MOLECLE THAT CODES IT, A VECTOR, A HOST CELL, A PROCEDURE FOR PRODUCING THE POLIPEPTIDE, USE OF ELEPIPETICO, AND PROAPILY USE |
US20040052799A1 (en) * | 1996-11-15 | 2004-03-18 | Astra Aktiebolag | Nucleic acid and amino acid sequences relating to Helicobacter pylori for diagnostics and therapeutics |
JP4581094B2 (en) | 2006-12-07 | 2010-11-17 | 国立大学法人 岡山大学 | Testing method for arteriosclerosis |
-
2016
- 2016-05-26 US US15/165,723 patent/US10577409B2/en active Active
- 2016-07-11 JP JP2016136878A patent/JP6776033B2/en active Active
-
2017
- 2017-04-24 PH PH12017000140A patent/PH12017000140B1/en unknown
- 2017-04-27 IL IL251997A patent/IL251997A0/en active IP Right Grant
- 2017-04-28 KR KR1020170055184A patent/KR102241619B1/en active IP Right Grant
- 2017-04-28 RU RU2017115201A patent/RU2751918C2/en active
- 2017-05-15 NZ NZ731906A patent/NZ731906A/en not_active IP Right Cessation
- 2017-05-15 AU AU2017203225A patent/AU2017203225B2/en not_active Ceased
- 2017-05-17 CA CA2967597A patent/CA2967597C/en active Active
- 2017-05-17 MY MYPI2017701770A patent/MY180272A/en unknown
- 2017-05-17 SG SG10201704029WA patent/SG10201704029WA/en unknown
- 2017-05-18 BR BR102017010401A patent/BR102017010401A2/en not_active Application Discontinuation
- 2017-05-19 MX MX2017006603A patent/MX2017006603A/en unknown
-
2019
- 2019-09-20 US US16/577,549 patent/US10808025B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
RU2017115201A (en) | 2018-10-29 |
US10808025B2 (en) | 2020-10-20 |
JP6776033B2 (en) | 2020-10-28 |
US20170342137A1 (en) | 2017-11-30 |
IL251997A0 (en) | 2017-07-31 |
RU2017115201A3 (en) | 2020-09-23 |
CA2967597C (en) | 2021-07-06 |
KR20170134199A (en) | 2017-12-06 |
AU2017203225B2 (en) | 2018-04-12 |
MX2017006603A (en) | 2018-08-28 |
US10577409B2 (en) | 2020-03-03 |
KR102241619B1 (en) | 2021-04-20 |
JP2017209100A (en) | 2017-11-30 |
NZ731906A (en) | 2018-02-23 |
SG10201704029WA (en) | 2017-12-28 |
AU2017203225A1 (en) | 2017-12-14 |
CA2967597A1 (en) | 2017-11-26 |
RU2751918C2 (en) | 2021-07-20 |
US20200010534A1 (en) | 2020-01-09 |
PH12017000140A1 (en) | 2018-09-17 |
PH12017000140B1 (en) | 2018-09-17 |
BR102017010401A2 (en) | 2020-04-28 |
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