MY178484A - A method for controling proteolytic degradation of recombinant proteins - Google Patents

A method for controling proteolytic degradation of recombinant proteins

Info

Publication number
MY178484A
MY178484A MYUI2010006296A MYUI2010006296A MY178484A MY 178484 A MY178484 A MY 178484A MY UI2010006296 A MYUI2010006296 A MY UI2010006296A MY UI2010006296 A MYUI2010006296 A MY UI2010006296A MY 178484 A MY178484 A MY 178484A
Authority
MY
Malaysia
Prior art keywords
controling
recombinant proteins
proteolytic degradation
recombinant
inhibiting
Prior art date
Application number
MYUI2010006296A
Inventor
Beng Ti Tey
Fui Chin Chong
Wen Siang Tan
Original Assignee
Univ Putra Malaysia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Putra Malaysia filed Critical Univ Putra Malaysia
Publication of MY178484A publication Critical patent/MY178484A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/115—Paramyxoviridae, e.g. parainfluenza virus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present innovation provides a method to enhance the recovery of recombinant N protein of Nipah virus produced in Escherichia coli, in which by identifying and inhibiting the specific proteases in the cell lysate are achieved by an integrated use of a bioinformatics tool and a protease inhibition experimental setup.
MYUI2010006296A 2009-07-30 2009-07-30 A method for controling proteolytic degradation of recombinant proteins MY178484A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/MY2009/000105 WO2011014051A1 (en) 2009-07-30 2009-07-30 A method for controlling proteolytic degradation of recombinant proteins

Publications (1)

Publication Number Publication Date
MY178484A true MY178484A (en) 2020-10-14

Family

ID=41351461

Family Applications (1)

Application Number Title Priority Date Filing Date
MYUI2010006296A MY178484A (en) 2009-07-30 2009-07-30 A method for controling proteolytic degradation of recombinant proteins

Country Status (2)

Country Link
MY (1) MY178484A (en)
WO (1) WO2011014051A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011056060A2 (en) * 2009-11-06 2011-05-12 Universiti Putra Malaysia Recombinant matrix protein of nipah virus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8232240B2 (en) * 2005-02-23 2012-07-31 The Brigham And Women's Hospital, Inc. Inhibitors of enveloped virus infectivity
EP1795606A1 (en) * 2005-08-11 2007-06-13 DIGILAB BioVisioN GmbH Method for screening for proteases and their substrates

Also Published As

Publication number Publication date
WO2011014051A1 (en) 2011-02-03

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