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Application filed by Bcs Business Consulting Services Pte Ltd, Grey Pacific Labs LlcfiledCriticalBcs Business Consulting Services Pte Ltd
Priority to MYPI2015002307ApriorityCriticalpatent/MY173240A/en
Priority claimed from PCT/IB2013/000360external-prioritypatent/WO2014140655A1/en
Publication of MY173240ApublicationCriticalpatent/MY173240A/en
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur
(AREA)
Abstract
Described is a method of synthesizing 6-(5-ethoxyhept-1-yl)bicyclo[3.3.0] octan-3- one by reacting 3-{5-ethoxyhept-1-yl) cyclopentene with dichloroketene. The resulting reaction products are reacted with acetic acid and zinc to produce 4-{5-ethoxy-hept-1- yl)bicyclo[3.2.0]heptan-6-one and 4-(5-ethoxyhept-1-yl}bloyclo [3.2.0]heptan-7-one, which are reacted with trimethylsulfonium iodide to produce 2-{5-ethoxyhept-1-yl)spiro[bicyclo[3.2. 0]heptane-6,2'-oxirane] and 4-(5-ethoxyhept-1-yl)spiro-[bicyclo-[3 .2. 0]heptane-6,2'-oxirane]. Lithium iodide is reacted with 2-{5-ethoxyhept-1-yl}spiro[bicyclo[3.2. 0]heptane-6,2'-oxirane] and 4-(5-ethoxyhept-1-yl)spiro-{bicyclo-[3.2.0]heptane-6,2'-oxirane] to produce 6-{5-ethoxyhept-1-yl}bicyclo[3.3.0]octan-3-one. A method of synthesizing 6-(5-methoxyhept-1-yl)bicyclo{3.3.0]octan-3-one is also described.
MYPI2015002307A2013-03-112013-03-11Method of synthesis
MY173240A
(en)