MY148891A - Novel antibiotic, bispolides a1, a2 and a3, and process for poducing the same - Google Patents

Novel antibiotic, bispolides a1, a2 and a3, and process for poducing the same

Info

Publication number
MY148891A
MY148891A MYPI20062247A MY148891A MY 148891 A MY148891 A MY 148891A MY PI20062247 A MYPI20062247 A MY PI20062247A MY 148891 A MY148891 A MY 148891A
Authority
MY
Malaysia
Prior art keywords
bispolide
hydrogen atom
methyl group
bispolides
poducing
Prior art date
Application number
Inventor
Keiichi Numata
Kunimoto Hotta
Seiji Shibahara
Shinichi Kondo
Satoshi Nimura
Noriyuki Okujo
Khor Siew Eim
Tan Lee Li
Annie George
Ng Szu Ting
Tan Chin Jye
Hironobu Iinuma
Yasuo Fukagawa
Original Assignee
Nimura Genetic Solutions Co Ltd
Forest Res Inst Malaysia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nimura Genetic Solutions Co Ltd, Forest Res Inst Malaysia filed Critical Nimura Genetic Solutions Co Ltd
Priority to MYPI20062247 priority Critical patent/MY148891A/en
Priority to JP2008515607A priority patent/JP4755248B2/en
Priority to PCT/JP2007/060304 priority patent/WO2007132937A1/en
Priority to EP07743739A priority patent/EP2025758A1/en
Priority to US12/300,468 priority patent/US8318684B2/en
Publication of MY148891A publication Critical patent/MY148891A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

IN THIS INVENTION, THERE IS PROVIDED A NOVEL ANTIBIOTIC, BISPOLIDE A1, BISPOLIDE A2 OR BISPOLIDE A3 WHICH IS A COMPOUND HAVING THE FORMULA (I): WHEREIN R� AND R� EACH DENOTE A HYDROGEN ATOM OR METHYL GROUP (-CH3), AND R� AND R� ARE EACH A HYDROGEN ATOM FOR BISPOLIDE A1; R� IS A HYDROGEN ATOM AND R� IS METHYL GROUP FOR BISPOLIDE A2; AND R� AND R� ARE EACH METHYL GROUP FOR BISPOLIDE A3. BISPOLIDE A1, BISPOLIDE A2 AND BISPOLIDE A3 MAY COLLECTIVELY BE NAMED AS A BISPOLIDE A AND ARE EACH AN ANTIBIOTIC HAVING A HIGH ANTIBACTERIAL ACTIVITY AGAINST BACTERIA SUCH AS GRAM-POSITIVE BACTERIA, INCLUDING METHICILLIN-RESISTANT STRAIN OF STAPHYLOCOCCUS AUREUS. IN THIS INVENTION, THERE IS ALSO PROVIDED A PROCESS OF PRODUCING A BISPOLIDE A COMPRISING CULTIVATING A MICROBIAL STAIN DESIGNATED AS MICROBISPORA SP. A34030 (DEPOSITED UNDER AN ACCESS NUMBER OF FERM BP-10505). THERE IS FURTHER PROVIDED A PHARMACEUTICAL COMPOSITION COMPRISING A BISPOLIDE A AS AN ACTIVE INGREDIENT.
MYPI20062247 2006-05-16 2006-05-16 Novel antibiotic, bispolides a1, a2 and a3, and process for poducing the same MY148891A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
MYPI20062247 MY148891A (en) 2006-05-16 2006-05-16 Novel antibiotic, bispolides a1, a2 and a3, and process for poducing the same
JP2008515607A JP4755248B2 (en) 2006-05-16 2007-05-15 Novel antibiotics, bisporides A1, A2 and A3 and bisporides B1, B2a, B2b and B3 and methods for producing these antibiotics
PCT/JP2007/060304 WO2007132937A1 (en) 2006-05-16 2007-05-15 NOVEL ANTIBIOTICS, BISPOLIDES A1, A2 AND A3 AND BISPOLIDES B1, B2a, B2b AND B3 AND METHOD FOR PRODUCING THE ANTIBIOTICS
EP07743739A EP2025758A1 (en) 2006-05-16 2007-05-15 NOVEL ANTIBIOTICS, BISPOLIDES A1, A2 AND A3 AND BISPOLIDES B1, B2a, B2b AND B3 AND METHOD FOR PRODUCING THE ANTIBIOTICS
US12/300,468 US8318684B2 (en) 2006-05-16 2007-05-15 Antibiotics, bispolides A1, A2, and A3 as well as bispolides B1, B2a, B2b and B3 and processes for producing said antibiotics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI20062247 MY148891A (en) 2006-05-16 2006-05-16 Novel antibiotic, bispolides a1, a2 and a3, and process for poducing the same

Publications (1)

Publication Number Publication Date
MY148891A true MY148891A (en) 2013-06-14

Family

ID=50287798

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20062247 MY148891A (en) 2006-05-16 2006-05-16 Novel antibiotic, bispolides a1, a2 and a3, and process for poducing the same

Country Status (1)

Country Link
MY (1) MY148891A (en)

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