MY146094A - Method for virus propagation in a bioreactor - Google Patents

Method for virus propagation in a bioreactor

Info

Publication number
MY146094A
MY146094A MYPI2010000490A MYPI2010000490A MY146094A MY 146094 A MY146094 A MY 146094A MY PI2010000490 A MYPI2010000490 A MY PI2010000490A MY PI2010000490 A MYPI2010000490 A MY PI2010000490A MY 146094 A MY146094 A MY 146094A
Authority
MY
Malaysia
Prior art keywords
bioreactor
virus
cells
virus propagation
culture
Prior art date
Application number
MYPI2010000490A
Inventor
Associate Professor Maizirwan Mel
Noorhayati Binti Esa
Original Assignee
Internat Islamic University Malaysia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Internat Islamic University Malaysia filed Critical Internat Islamic University Malaysia
Priority to MYPI2010000490A priority Critical patent/MY146094A/en
Priority to PCT/MY2011/000006 priority patent/WO2011093692A1/en
Publication of MY146094A publication Critical patent/MY146094A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18151—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

THE PRESENT INVENTION RELATES TO A METHOD FOR VIRUS PROPAGATION IN A BIOREACTOR (10) COMPRISING THE STEPS OF: FIRSTLY, CULTURING A CELL IN A BIOREACTOR TO PRODUCE MORE CELLS TO FORM A BIOREACTOR CULTURE IN THE PRESENCE OF MICROCARRIERS (11), WHEREIN THE BIOREACTOR IS A SPINNER VESSEL OR STIRRED TANK BIOREACTOR; THEN, INOCULATING THE CELLS WITH VIRUS (12); AND SUBSEQUENTLY, INCUBATING THE VIRUS WITH THE BIOREACTOR CULTURE (13), WITH TEMPERATURE OF 37°C, AGITATION SPEED OF 30-70 RPM, PH 7.2, AND DISSOLVED OXYGEN CONTENT (PO2) OF 30%; WHEREIN THE VIRUS IS NEWCASTLE DISEASE VIRUS (NDV) AND THE CELLS ARE VERO CELLS.
MYPI2010000490A 2010-01-29 2010-01-29 Method for virus propagation in a bioreactor MY146094A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MYPI2010000490A MY146094A (en) 2010-01-29 2010-01-29 Method for virus propagation in a bioreactor
PCT/MY2011/000006 WO2011093692A1 (en) 2010-01-29 2011-01-26 Method for newcastle disease virus propagation in a bioreactor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI2010000490A MY146094A (en) 2010-01-29 2010-01-29 Method for virus propagation in a bioreactor

Publications (1)

Publication Number Publication Date
MY146094A true MY146094A (en) 2012-06-29

Family

ID=44319536

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2010000490A MY146094A (en) 2010-01-29 2010-01-29 Method for virus propagation in a bioreactor

Country Status (2)

Country Link
MY (1) MY146094A (en)
WO (1) WO2011093692A1 (en)

Also Published As

Publication number Publication date
WO2011093692A1 (en) 2011-08-04

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