MY140691A - Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them - Google Patents
Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising themInfo
- Publication number
- MY140691A MY140691A MYPI20043429A MYPI20043429A MY140691A MY 140691 A MY140691 A MY 140691A MY PI20043429 A MYPI20043429 A MY PI20043429A MY PI20043429 A MYPI20043429 A MY PI20043429A MY 140691 A MY140691 A MY 140691A
- Authority
- MY
- Malaysia
- Prior art keywords
- medicament
- pentafluorosulfanylphenyl
- processes
- preparation
- substituted benzoylguanidines
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PENTAFLUOROSULFANYLPHENYL-SUBSTITUTED BENZOYLGUANIDINES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENT OR DIAGNOSTIC AID, AND MEDICAMENT COMPRISING THEM.PENTAFLUOROSULFANYLPHENYL-SUBSTITUTED BENZOYLGUANIDINES OF THE FORMULAE I AND II IN WHICH R1, R1', R2, R2', R3, R3', R4 AND X HAVE THE MEANINGS INDICATED IN THE CLAIMS, ARE SUITABLE AS ANTIARRHYTHMIC MEDICAMENTS WITH A CARDIOPROTECTIVE COMPONENT FOR THE PROPHYLAXIS OF INFARCTION AND TREATMENT OF INFARCTION AND FOR THE TREATMENT OF ANGINA PECTORIS.THEY ALSO INHIBIT PREVENTIVELY THE PATHOPYSIOLOGICAL PROCESSES ASSOCIATED WITH THE DEVELOPMENT OF ISCHEMIA-INDUCED DAMAGE, ESPECIALLY IN THE TRIGGERING OF ISCHEMIA-INDUCED CARDIAC ARRHYTHMIAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10338554A DE10338554A1 (en) | 2003-08-22 | 2003-08-22 | Pentafluorosulfanylphenyl-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
MY140691A true MY140691A (en) | 2010-01-15 |
Family
ID=34223114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI20043429A MY140691A (en) | 2003-08-22 | 2004-08-20 | Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1658266B1 (en) |
JP (1) | JP4516965B2 (en) |
AR (1) | AR045384A1 (en) |
AT (1) | ATE477239T1 (en) |
AU (1) | AU2004268762B2 (en) |
BR (1) | BRPI0413798A (en) |
CA (1) | CA2536459A1 (en) |
DE (2) | DE10338554A1 (en) |
IL (1) | IL173546A0 (en) |
MX (1) | MXPA06001466A (en) |
MY (1) | MY140691A (en) |
PE (1) | PE20050279A1 (en) |
TW (1) | TW200524850A (en) |
WO (1) | WO2005021492A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
OA13285A (en) * | 2003-11-13 | 2007-01-31 | Sanofi Aventis Deutschland | Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same. |
WO2009028514A1 (en) * | 2007-08-28 | 2009-03-05 | Ube Industries, Ltd. | Method for producing pentafluorosulfanylbenzene compound and novel pentafluorosulfanylbenzene compound |
US9682931B2 (en) | 2013-11-01 | 2017-06-20 | Ube Industries, Ltd. | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof |
LT3649109T (en) * | 2017-07-04 | 2021-09-27 | Sanofi | Ethynyl compounds, their preparation and their therapeutic use for the treatment of malaria |
KR102668895B1 (en) * | 2018-10-30 | 2024-05-23 | 스미토모 고무 코교 카부시키카이샤 | Golf ball |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE147375T1 (en) * | 1992-09-22 | 1997-01-15 | Hoechst Ag | BENZOYLGUANIDINES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIARRHYTHMICS |
DE4417004A1 (en) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoroalkyl-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them |
DE4432101A1 (en) * | 1994-09-09 | 1996-03-14 | Hoechst Ag | Amino acid-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic agent, and medicament containing them |
DK0723956T3 (en) * | 1995-01-30 | 2000-04-17 | Hoechst Ag | Basically substituted benzoylguanidines, process for their preparation, use thereof as a drug or diagnosis |
JPH10237077A (en) * | 1997-02-26 | 1998-09-08 | Yamanouchi Pharmaceut Co Ltd | Heteroaryl-substituted propionyl guanidine derivative |
DE19849722A1 (en) * | 1998-10-28 | 2000-05-04 | Aventis Pharma Gmbh | Substituted phenyl-alkenoylguanidines, processes for their preparation, their use as medicaments or diagnostic agents and medicaments containing them |
DE10024319A1 (en) * | 2000-05-17 | 2001-11-22 | Merck Patent Gmbh | New bis-acylguanidine compounds are subtype-1 cellular sodium ion-proton antiporter inhibitors useful e.g. for treating arrhythmia, angina pectoris, infarction and insulin-independent diabetes mellitus |
DE10222192A1 (en) * | 2002-05-18 | 2003-11-27 | Aventis Pharma Gmbh | New pentafluorosulfanylbenzoylguanidine compound useful for treating e.g. infarction, angina pectoris and stroke |
DE10226462A1 (en) * | 2002-06-13 | 2003-12-24 | Aventis Pharma Gmbh | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their use as medicament, and medicament containing them |
-
2003
- 2003-08-22 DE DE10338554A patent/DE10338554A1/en not_active Withdrawn
-
2004
- 2004-08-02 PE PE2004000732A patent/PE20050279A1/en not_active Application Discontinuation
- 2004-08-12 AU AU2004268762A patent/AU2004268762B2/en not_active Ceased
- 2004-08-12 DE DE502004011523T patent/DE502004011523D1/en active Active
- 2004-08-12 CA CA002536459A patent/CA2536459A1/en not_active Abandoned
- 2004-08-12 EP EP04764024A patent/EP1658266B1/en not_active Not-in-force
- 2004-08-12 WO PCT/EP2004/009020 patent/WO2005021492A1/en active Application Filing
- 2004-08-12 JP JP2006523580A patent/JP4516965B2/en not_active Expired - Fee Related
- 2004-08-12 BR BRPI0413798-1A patent/BRPI0413798A/en not_active IP Right Cessation
- 2004-08-12 MX MXPA06001466A patent/MXPA06001466A/en active IP Right Grant
- 2004-08-12 AT AT04764024T patent/ATE477239T1/en not_active IP Right Cessation
- 2004-08-19 TW TW093124904A patent/TW200524850A/en unknown
- 2004-08-20 AR ARP040103003A patent/AR045384A1/en not_active Application Discontinuation
- 2004-08-20 MY MYPI20043429A patent/MY140691A/en unknown
-
2006
- 2006-02-05 IL IL173546A patent/IL173546A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0413798A (en) | 2006-10-31 |
MXPA06001466A (en) | 2006-05-15 |
JP4516965B2 (en) | 2010-08-04 |
JP2007503378A (en) | 2007-02-22 |
AU2004268762B2 (en) | 2009-06-25 |
IL173546A0 (en) | 2006-07-05 |
DE10338554A1 (en) | 2005-03-31 |
DE502004011523D1 (en) | 2010-09-23 |
AU2004268762A1 (en) | 2005-03-10 |
AR045384A1 (en) | 2005-10-26 |
TW200524850A (en) | 2005-08-01 |
EP1658266A1 (en) | 2006-05-24 |
WO2005021492A1 (en) | 2005-03-10 |
CA2536459A1 (en) | 2005-03-10 |
EP1658266B1 (en) | 2010-08-11 |
PE20050279A1 (en) | 2005-06-01 |
ATE477239T1 (en) | 2010-08-15 |
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