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Priority to MYPI20051572priorityCriticalpatent/MY137442A/en
Publication of MY137442ApublicationCriticalpatent/MY137442A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PARTICLES ARE PROVIDED WHICH ARE SUITABLE FOR DELIVERY FROM A PARTICLE-MEDIATED DELIVERY DEVICE. THE PARTICLES ARE OBTAINED BY PRECIPITATING A NUCLEIC ACID ON INERT METAL CARRIER PARTICLES IN THE PRESENCE OF A NUCLEIC ACID CONDENSING AGENT AND A METAL ION CHELATING AGENT. ALSO DESCRIBED ARE PROCESSES FOR PREPARING THE PARTICLES, AND THERAPEUTIC METHODS USING THE PARTICLES INCLUDING METHODS OF NUCLEIC ACID IMMUNISATION AND GENE THERAPY.