MY137288A - New process for the synthesis of n-[(s)-1-ethoxycarbonylbutyl]-(s)-alanine and application in the synthesis of perindopril - Google Patents
New process for the synthesis of n-[(s)-1-ethoxycarbonylbutyl]-(s)-alanine and application in the synthesis of perindoprilInfo
- Publication number
- MY137288A MY137288A MYPI20043998A MYPI20043998A MY137288A MY 137288 A MY137288 A MY 137288A MY PI20043998 A MYPI20043998 A MY PI20043998A MY PI20043998 A MYPI20043998 A MY PI20043998A MY 137288 A MY137288 A MY 137288A
- Authority
- MY
- Malaysia
- Prior art keywords
- synthesis
- perindopril
- application
- ethoxycarbonylbutyl
- alanine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCESS FOR THE SYNTHESIS OF THE COMPOUND OF FORMULA (I) : APPLICATION IN THE SYNTHESIS OF PERINDOPRIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03292405A EP1400531B1 (en) | 2003-09-30 | 2003-09-30 | Process for the synthesis of N-((S)-1-(ethoxycarbonyl)butyl)-(S)-alanine and use in the synthesis of perindopril |
Publications (1)
Publication Number | Publication Date |
---|---|
MY137288A true MY137288A (en) | 2009-01-30 |
Family
ID=31897022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI20043998A MY137288A (en) | 2003-09-30 | 2004-09-29 | New process for the synthesis of n-[(s)-1-ethoxycarbonylbutyl]-(s)-alanine and application in the synthesis of perindopril |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1400531B1 (en) |
AR (1) | AR045954A1 (en) |
AT (1) | ATE315046T1 (en) |
DE (1) | DE60303104T2 (en) |
DK (1) | DK1400531T3 (en) |
ES (1) | ES2256693T3 (en) |
MY (1) | MY137288A (en) |
SI (1) | SI1400531T1 (en) |
WO (1) | WO2005033128A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI21800A (en) | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | New procedure of synthesis of perindopril |
EP1792896A1 (en) | 2005-12-01 | 2007-06-06 | KRKA, tovarna zdravil, d.d., Novo mesto | Process for the preparation of perindopril and salts thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2807037B1 (en) * | 2000-03-31 | 2002-05-10 | Adir | NOVEL PROCESS FOR SYNTHESIS OF N - [(s) -1- CARBOXYBUTYL] - (S) -ALANINE ESTERS AND APPLICATION TO THE SYNTHESIS OF PERINDOPRIL |
FR2807430B1 (en) * | 2000-04-11 | 2002-05-17 | Adir | NOVEL PROCESS FOR THE SYNTHESIS OF N - [(S) -1- CARBOXYBUTYL] - (S) -ALANINE ESTERS AND APPLICATION TO THE SYNTHESIS OF PERINDOPRIL |
-
2003
- 2003-09-30 SI SI200330162T patent/SI1400531T1/en unknown
- 2003-09-30 DE DE60303104T patent/DE60303104T2/en not_active Expired - Lifetime
- 2003-09-30 ES ES03292405T patent/ES2256693T3/en not_active Expired - Lifetime
- 2003-09-30 EP EP03292405A patent/EP1400531B1/en not_active Expired - Lifetime
- 2003-09-30 DK DK03292405T patent/DK1400531T3/en active
- 2003-09-30 AT AT03292405T patent/ATE315046T1/en active
-
2004
- 2004-09-29 MY MYPI20043998A patent/MY137288A/en unknown
- 2004-09-29 AR ARP040103526A patent/AR045954A1/en unknown
- 2004-09-29 WO PCT/FR2004/002464 patent/WO2005033128A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
DE60303104T2 (en) | 2006-11-02 |
ES2256693T3 (en) | 2006-07-16 |
DE60303104D1 (en) | 2006-03-30 |
DK1400531T3 (en) | 2006-05-15 |
ATE315046T1 (en) | 2006-02-15 |
WO2005033128A1 (en) | 2005-04-14 |
EP1400531A1 (en) | 2004-03-24 |
AR045954A1 (en) | 2005-11-16 |
SI1400531T1 (en) | 2006-04-30 |
EP1400531B1 (en) | 2006-01-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA84271C2 (en) | Formate salt of o-desmethyl-venlafaxine | |
GEP20053600B (en) | 3-(4-Amidopyrrol-2-Ylmethlidene)-2- Indolinone Derivatives as Protein Kinase Inhibitors | |
GEP20105036B (en) | Perindopril | |
CY1106544T1 (en) | METHOD OF SYNTHESIS OF HYPERINDOPRIL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | |
AP1787A (en) | Novel perindopril salt and pharmaceutical compositions containing same. | |
NO20055257L (en) | New Process for the Synthesis of S-Indoline-2-Carboxylic Acid and its Use in the Synthesis of Perindopril | |
TW200508199A (en) | Novel compound | |
HK1096409A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
MY136938A (en) | New process for the synthesis of perindopril and its pharmaceutically acceptable salts | |
MY139159A (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
CY1108238T1 (en) | METHOD OF COMPOSITION OF PERINDOPRIL AND ITS PHARMACEUTICAL SALTS | |
MY135359A (en) | New process for the synthesis of perindopril and pharmaceutically acceptable salts thereof | |
MY136288A (en) | New process for the synthesis of perindopril and its pharmaceutically acceptable salts | |
MY137288A (en) | New process for the synthesis of n-[(s)-1-ethoxycarbonylbutyl]-(s)-alanine and application in the synthesis of perindopril | |
MY136638A (en) | New process for the synthesis of perindopril and its pharmaceutically acceptable salts | |
MY137391A (en) | New process for the synthesis of n-[(s)-1-ethoxycarbonylbutyl]-(s)-alanine and application in the synthesis of perindopril | |
MY136989A (en) | New process for the synthesis of perindopril and pharmaceutically acceptable salts thereof | |
CY1106543T1 (en) | METHOD OF SYNTHESIS OF HYPERINDOPRIL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | |
EA200600501A1 (en) | NEW METHOD FOR SYNTHESIS OF COMPLEX ETHERS N - [(S) -1-CARBOXYBUTYL] - (S) -ALANINE AND THEIR APPLICATION FOR PERINDOPRIL SYNTHESIS | |
HK1096407A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
MY139443A (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
WO2007085933A3 (en) | Process for the preparation of n-[1-(s)-ethoxycarbonyl-1-butyl]-(s)-alanine-dmt complex and its use in the preparation of perindopril |