MY132049A - Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands - Google Patents

Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands

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Publication number
MY132049A
MY132049A MYPI9503592A MY132049A MY 132049 A MY132049 A MY 132049A MY PI9503592 A MYPI9503592 A MY PI9503592A MY 132049 A MY132049 A MY 132049A
Authority
MY
Malaysia
Prior art keywords
aminomethyl
imidazole derivatives
substituted imidazole
dopamine receptor
certain
Prior art date
Application number
Inventor
Thurkauf Andrew
Raymond F Horvath
Jun Yuan
John M Peterson
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Publication of MY132049A publication Critical patent/MY132049A/en

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Abstract

DISCLOSED ARE COMPOUNDS OF THE FORMULA :(FORMULA I)WHEREIN R1 REPRESENTS OPTIONALLY SUBSTITUTED ARYL, HETEROARYL, ARYLALKYL, OR CYCLOALKYL GROUPS; X, Z, AND Y ARE OPTIONALLY SUBSTITUTED NITROGEN OR CARBON ATOMS; R3 AND R4 ARE INORGANIC SUBSTITUTENTS WHICH MAY TOGETHER FORM RING STRUCTURES; M IS ZERO, ONE OR TWO; AND R5 AND R6 ARE ARE ORGANIC OR INORGANIC SUBSTITUENTS; AND THE PHARMACEUTICALLY ACCEPTABLE ADDITION SALTS THEREOF, WHICH COMPOUNDS ARE HIGHLY SELECTIVE PARTIAL AGONISTS OR ANTAGONISTS AT BRAIN DOPAMINE RECEPTOR SUBTYPES OR PRODRUGS THEREOF AND ARE USEFUL IN THE DIAGNOSIS AND TREATMENT OF EFFECTIVE DISORDES SUCH AS SCHIZOPHRENIA AND DEPRESSION AS WELL AS CERTAIN MOVEMENT DISORDES SUCH AS PARKINSONISM.
MYPI9503592 1994-11-23 1995-11-23 Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands MY132049A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34415494A 1994-11-23 1994-11-23

Publications (1)

Publication Number Publication Date
MY132049A true MY132049A (en) 2007-09-28

Family

ID=23349285

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI9503592 MY132049A (en) 1994-11-23 1995-11-23 Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands

Country Status (3)

Country Link
IL (1) IL116090A0 (en)
MY (1) MY132049A (en)
ZA (1) ZA959911B (en)

Also Published As

Publication number Publication date
IL116090A0 (en) 1996-01-31
ZA959911B (en) 1997-08-22

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