MY131832A - New heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them - Google Patents

Abstract

THE PRESENT INVENTION RELATES TO NOVEL ANTIOBESITY AND HYPOCHOLESTEROLEMIC COMPOUNDS, THEIR DERIVATIVES, THEIR ANALOGS,THEIR TAUTOMERIC FORMS, THEIR STEREO-ISOMERS,THEIR POLYMORPHS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, THEIR PHARMACEUTICALLY ACCEPTABLE SOLVATES AND PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS CONTAINING THEM.MORE PARTICULARLY, THE PRESENT INVENTION RELATES TO NOVEL ß-ARYL-ALPHA-OXYSUBSTITUTED ALKYLCARBOXYLIC ACIDS OF THE GENERAL FORMULA (I), THEIR DERIVATIVES, THEIR ANALOGS,THEIR TAUTOMERIC FORMS,THEIR STEREOISOMERS, THEIR POLYMORPHS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, THEIR PHARMACEUTICALLY ACCEPTABLE SOLVATES AND PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS CONTAINING THEM. (I) THE PRESENT INVENTION ALSO RELATES TO A PROCESS FOR THE PREPARATION OF THE ABOVE SAID NOVEL COMPOUNDS, THEIR ANALOGS, THEIR DERIVATIVES, THEIR TAUTOMERICS FORMS, THEIR STEREOISOMERS, THEIR POLYMORPHS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, THEIR PHARMACEUTICALLY ACCEPTABLE SOLVATES,NOVEL INTERMEDIATES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.