MY113497A - Peptides and compounds that bind to a receptor - Google Patents

Peptides and compounds that bind to a receptor

Info

Publication number
MY113497A
MY113497A MYPI96002267A MYPI19962267A MY113497A MY 113497 A MY113497 A MY 113497A MY PI96002267 A MYPI96002267 A MY PI96002267A MY PI19962267 A MYPI19962267 A MY PI19962267A MY 113497 A MY113497 A MY 113497A
Authority
MY
Malaysia
Prior art keywords
peptides
bind
peptide mimetics
receptor
compounds
Prior art date
Application number
MYPI96002267A
Inventor
J Duffin David
E Cwirla Steven
M Gates Christian
J Schatz Peter
S Johnson Sherril
C Mattheakis Larry
W Barrett Ronald
C Wrighton Nicholas
R Wagstrom Christopher
J Dower William
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MY113497A publication Critical patent/MY113497A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

DESCRIBED ARE PEPTIDES AND PEPTIDE MIMETICS THAT BIND TO AND ACTIVATE THE THROMBOPOIETIN RECEPTOR. SUCH PEPTIDES AND PEPTIDE MIMETICS ARE USEFUL IN METHODS FOR TREATING HEMATOLOGICAL DISORDERS AND PARTICULARLY, THROMBOCYTOPENIA RESULTING FROM CHEMOTHERAPY, RADIATION THERAPY, OR BONE MARROW TRANSFUSIONS AS''WELL AS IN DIAGNOSTIC METHODS EMPLOYING LABELED PEPTIDES AND PEPTIDE MIMETICS.
MYPI96002267A 1995-06-07 1996-06-06 Peptides and compounds that bind to a receptor MY113497A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US47360495A 1995-06-07 1995-06-07
US48530195A 1995-06-07 1995-06-07
US48409095A 1995-06-07 1995-06-07
US47237195A 1995-06-07 1995-06-07
US47616895A 1995-06-07 1995-06-07
US47812895A 1995-06-07 1995-06-07

Publications (1)

Publication Number Publication Date
MY113497A true MY113497A (en) 2002-03-30

Family

ID=27560032

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI96002267A MY113497A (en) 1995-06-07 1996-06-06 Peptides and compounds that bind to a receptor

Country Status (5)

Country Link
AU (1) AU6046696A (en)
HR (1) HRP960256A2 (en)
MY (1) MY113497A (en)
WO (1) WO1996040189A1 (en)
YU (1) YU34196A (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US20030069177A1 (en) 2000-05-16 2003-04-10 Genentech, Inc. Method for treating cartilage disorders
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
CN1810832B (en) 1998-10-23 2012-12-12 麒麟-安姆根有限公司 Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
JP4937435B2 (en) 1998-11-05 2012-05-23 修一 広野 Novel compounds and their pharmaceutical uses
CA2355163A1 (en) * 1998-12-18 2000-06-29 Mount Sinai Hospital Three dimensional structure of a sterile alpha motif domain
EP1141014B1 (en) 1999-01-06 2004-12-08 Genentech, Inc. Insulin-like growth factor (igf) i mutant variant
WO2001010891A2 (en) * 1999-08-05 2001-02-15 Research Corporation Technologies, Inc. Il-16 antagonists
EP1149906A1 (en) * 2000-04-25 2001-10-31 Pliva, Farmaceutska, Industrija, Dionicko Drustvo Thrombopoietin receptor modulating peptide
US7396917B2 (en) 2000-12-05 2008-07-08 Alexion Pharmaceuticals, Inc. Rationally designed antibodies
ES2258558T3 (en) * 2000-12-05 2006-09-01 Alexion Pharmaceuticals, Inc. RATIONALALLY DESIGNED ANTIBODIES.
JP2004532203A (en) * 2001-03-21 2004-10-21 ザ、ユニバーシティ、オブ、テキサス、システム Glycosaminoglycan inhibitors
US7332474B2 (en) 2001-10-11 2008-02-19 Amgen Inc. Peptides and related compounds having thrombopoietic activity
CA2495184A1 (en) 2002-08-14 2004-02-26 Nissan Chemical Industries, Ltd. Thrombopoietin receptor activators and process for their production
MXPA05003057A (en) 2002-09-18 2006-04-18 Johnson & Johnson Methods of increasing platelet and hematopoietic stem cell production.
TWI324593B (en) 2002-10-09 2010-05-11 Nissan Chemical Ind Ltd Pyrazolone compounds and thrombopoietin receptor activator
EP1628686A2 (en) 2003-05-12 2006-03-01 Affymax, Inc. Spacer moiety for poly (ethylene glycol)-modified peptides
SI1629007T1 (en) 2003-05-12 2009-10-31 Affymax Inc Novel peptides that bind to the erythropoietin receptor
WO2004101611A2 (en) 2003-05-12 2004-11-25 Affymax, Inc. Peptides that bind to the erythropoietin receptor
CA2588979C (en) 2004-12-08 2013-01-22 Nissan Chemical Industries, Ltd. 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators
RU2401259C2 (en) 2004-12-14 2010-10-10 Ниссан Кемикал Индастриз, ЛТД Amide compounds and thrombopoietin receptor activators
US7550433B2 (en) 2005-06-03 2009-06-23 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
JP5071375B2 (en) 2005-07-15 2012-11-14 日産化学工業株式会社 Thiophene compound and thrombopoietin receptor activator
KR101290484B1 (en) 2005-07-20 2013-07-26 닛산 가가쿠 고교 가부시키 가이샤 Pyrazole compounds and thrombopoietin receptor activators
JP5205967B2 (en) 2005-11-07 2013-06-05 日産化学工業株式会社 Hydrazide compounds and thrombopoietin receptor activators
WO2007142308A1 (en) 2006-06-07 2007-12-13 Nissan Chemical Industries, Ltd. Nitrogen-containing heterocyclic compound and thrombopoietin receptor activator
US7981425B2 (en) 2006-06-19 2011-07-19 Amgen Inc. Thrombopoietic compounds
EP1897888A1 (en) * 2006-09-05 2008-03-12 AplaGen GmbH Peptides binding the TPO receptor
WO2008028645A1 (en) * 2006-09-05 2008-03-13 Aplagen Gmbh Peptides binding the tpo receptor
EP2118127A4 (en) 2007-01-31 2010-12-01 Affymax Inc Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules
WO2009029682A1 (en) * 2007-08-28 2009-03-05 Rigel Pharmaceuticals, Inc. Combination therapy with syk kinase inhibitor
US8889732B2 (en) 2009-10-23 2014-11-18 Nissan Chemical Industries, Ltd. Fused heterocyclic compounds and thrombopoietin receptor activators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198424A (en) * 1989-03-08 1993-03-30 Board Of Regents Of The University Of Oklahoma Functionally active selectin-derived peptides

Also Published As

Publication number Publication date
AU6046696A (en) 1996-12-30
WO1996040189A1 (en) 1996-12-19
YU34196A (en) 1999-03-04
HRP960256A2 (en) 1998-02-28

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