MY106930A - Controlled release device - Google Patents
Controlled release deviceInfo
- Publication number
- MY106930A MY106930A MYPI93000856A MYPI19930856A MY106930A MY 106930 A MY106930 A MY 106930A MY PI93000856 A MYPI93000856 A MY PI93000856A MY PI19930856 A MYPI19930856 A MY PI19930856A MY 106930 A MY106930 A MY 106930A
- Authority
- MY
- Malaysia
- Prior art keywords
- active substance
- core
- exposed
- release
- fluid medium
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 5
- 238000004090 dissolution Methods 0.000 abstract 4
- 239000012530 fluid Substances 0.000 abstract 4
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 abstract 1
- 229960000620 ranitidine Drugs 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
THE INVENTION RELATES TO A DEVICE FOR THE RELEASE OF AT LEAST ONE ACTIVE SUBSTANCE (E.G. RANITIDINE) INTO A FLUID MEDIUM BY DISSOLUTION COMPRISING A COVERING, WHICH IS IMPERMEABLE TO THE ACTIVE SUBSTANCE AND THE FLUID, HAVING AT LEAST ONE OPERTURE THEREIN AND DEFINING A SHAPED CAVITY, THE CAVITY BEING FILLED BY A SHAPED CORE COMPRISING THE ACTIVE SUBSTANCE, AND WHEREIN:A) ON EXPOSURE OF THE DEVICE TO THE FLUID MEDIUM, A SURFACE OF THE CORE IS EXPOSED AND DISSOLUTION OF THE SURFACE BY THE FLUID MEDIUM CAUSES A CHANGE IN AT LEAST ONE DIMENSION OF THE AREA OF THE SURFACE, WHILST THE SURFACE AREA OF THE EXPOSED SURFACE REMAINS SUBSTANTIALLY CONSTANT OVER AT LEAST 50 OF THE TOTAL DISSOLUTION TIME OF THE CORE; ORB) THE ACTIVE SUBSTANCE IS DISPOSED IN A MATRIX OF AN INERT INSOLUBLE EXCIPIENT, THE DEVICE BEING AXIALLY SYMMETRICAL, WITH ITS APERTURE BEING PERIPHERALLY DISPOSED SO THAT THE RELEASE SURFACE OF CORE WHICH IS EXPOSED THROUGH THE APERTURE IS SUBSTANTIALLY CYLINDRICAL OR PART OF A CYLINDER IN SHAPE, WHEREBY TO ALLOW SUBSTANTIALLY CONSTANT RELEASE OF THE ACTIVE SUBSTANCE OVER AT LEAST PART OF THE DISSOLUTION TIME; AND PROCESSES FOR ITS PREPARATION.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI93000856A MY106930A (en) | 1993-05-07 | 1993-05-07 | Controlled release device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MYPI93000856A MY106930A (en) | 1993-05-07 | 1993-05-07 | Controlled release device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY106930A true MY106930A (en) | 1995-08-30 |
Family
ID=80001943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI93000856A MY106930A (en) | 1993-05-07 | 1993-05-07 | Controlled release device |
Country Status (1)
| Country | Link |
|---|---|
| MY (1) | MY106930A (en) |
-
1993
- 1993-05-07 MY MYPI93000856A patent/MY106930A/en unknown
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