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Priority claimed from US06/535,503external-prioritypatent/US4501890A/en
Priority claimed from US06/535,474external-prioritypatent/US4521421A/en
Priority claimed from US06/575,126external-prioritypatent/US4528290A/en
Priority claimed from EP84305684Aexternal-prioritypatent/EP0139393B1/en
Application filed by Lilly Co ElifiledCriticalLilly Co Eli
Publication of MY101854ApublicationCriticalpatent/MY101854A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
TRANS-(?)-2-AMINO (OR SUBSTITUTED AMINO)-4-(PERMISSIBLY-SUBSTITUTED) -6-C1-C3 ALKYL (OR ALLYL)-5, 5A, -6, 7, 8, 9, 9A, 10-OCTAHYDROPYRIMIDO [4, 5-G] QUINOLINES, THE CORRESPONDING TRANS-(-) AND TRANS-(?)-STEREOISOMERS AND SALTS THEREOF, USEFUL IN TREATING PARKINSON'S SYNDROME, SEXUAL DYSFUNCTION, DEPRESSION, HYPERTENSION, AND PROLACTIN RELATED DISEASES, AND INTERMEDIATES USEFUL FOR THE SYNTHESIS THEREOF, ARE DISCLOSED. THE PRODUCTS ARE PREPARED BY CONDENSING AN APPROPRIATE KETONE WITH THE APPROPRIATELY SUBSTITUTED GUANIDINE.
MYPI87001872A1983-09-261987-09-22Improvements in and relating to pyrimido-(4,5-g) quinolines and intermediates
MY101854A
(en)