MXPA99008992A - Synergetic fungicide composition - Google Patents

Abstract

Disclosed is a synergetic fungicide composition comprising propamocarbe and a derivative of phosphorous acid. The invention further proposes a process for the preventive or curative combat of phytopathogenic mushrooms which employs this composition.

Description

SYNERGIC FUNGICIDE COMPOSITION DESCRIPTION OF THE INVENTION The subject of the present invention is a synergistic fungicide comprising the propamocarb and a phosphorous acid derivative, and a process that puts said composition into operation and is intended to protect, in a curative or preventive manner, the crops against attacks by fungi. It is always desirable to improve the spectrum of activity and the effectiveness of such compounds with fungicidal action, or to strengthen them by associating them with other molecules in order to obtain a more functional product (association with a systemic fungicide, these fungicides are always molecules of the contact type). ") or even prevent the appearance of fungal strains resistant to these new fungicides It is also very desirable to have fungicide products that benefit from a persistence of improved action, with a view to spacing in time the number of phytosanitary treatments necessary for the Good control of parasites In all cases it is particularly advantageous to be able to decrease the quantity of products REF .: 31386 chemicals expanded in the environment, always ensuring functional protection of crops against fungal attacks. It has now been found that one (or several) of the foregoing objectives could be achieved thanks to the fungicidal composition according to the present invention. The present invention therefore firstly aims at a synergistic fungicidal composition comprising as compound A the propamocarb, also called propyl 3- (dimethylamino) propylcarbamate, and at least one fungicidal compound B selected from the group comprising the phosphorous acid derivatives such as metal phosphites such as fosetyl-Al, and phosphorous acid itself, and its alkaline or alkaline-earth salts. The fungicidal composition according to the invention advantageously comprises the components A and B in an A / B weight ratio comprised between 1/12 and 12/1, preferably between 1/3 and 3/1, and even more advantageously in a ratio equal to 1. It is well understood that said fungicidal composition can include a single compound B or more than one of such compounds, for example 1, 2 or 3 compounds B according to the use to which it is intended. Among the most especially preferred meanings of compound B defined above, even the fosetyl Al is preferred. Preferably, the composition is not applied on the lawn. In a perfectly unexpected manner, the composition according to the invention then significantly improves the action of the active materials placed separately for a number of fungi particularly harmful to crops, in particular, such as vineyards or nightshades. This improvement is mainly translated into a decrease in the doses of each of the constituents, which is particularly advantageous for users and the environment. The fungicidal product thus presents the synergistic properties attested by the application of the Tammes method, "Isoboles, a graphic representation of synergism in pesticides" Netherlands Journal of Plant Pathology, 70 (1964), p. 73.80. Preferably, when the compound B is the fosetyl-Al, the ratio A / B is comprised between 1/3 and 3/1, and even more advantageously this ratio is equal to 1 for the set of crops considered. The structures corresponding to the common names of active substances A and B are indicated in at least 1 of the following 2 works: * The pesticide manual "published by Clive TOMLIN and published by the British Crop Protection Council, 10th edition (pages 843 and 530 The phytosanitary index of 1994, edited by the Association of Coordination Technique Agricole, 30th edition The fungicidal composition according to the invention comprises, as an active material, a compound A and at least one compound B in mixture with the solid carriers or liquids, acceptable in agriculture and / or surfactants equally acceptable in agriculture., the inert and customary carriers and the usual surfactants are usable. These compositions coat not only the ready-to-apply compositions on the crop to be treated by means of a suitable device, such as a spray device, but also the concentrated commercial compositions that must be diluted before application on the crop. The combination of at least one compound A with at least one compound B is designated by active material. These compositions can also contain any kind of other ingredients, such as, for example, protective colloids, adhesives, thickeners, thixotropic agents, penetrating agents , stabilizers, hijackers, etc. More generally, compounds A and B can be combined with all solid or liquid additives corresponding to the usual techniques of preparing a formulation. In a general manner, the compositions according to the invention usually contain 0.05 to 95% (by weight) of active material, one or more solid or liquid carriers and, optionally, one or more surfactants. By the term "carrier", in the present case, an organic or mineral material, natural or synthetic, is designated, with which the active material is combined to facilitate its application on the aerial parts of the plant. This carrier is therefore generally inert and must be acceptable in agriculture, mainly on the treated plant. The carrier can be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers, etc.) or liquid (water, alcohols, mainly butanol, etc.). The surfactant may be an emulsifying, dispersing or wetting agent of the ionic or non-ionic type or a mixture of such surfactants. Mention may be made, for example, of salts of polyacrylic acids, salts of lignosulfonic acids, salts of phenolsulfonic or naphthalenesulfonic acids, polycondensates of ethylene oxide on fatty alcohols or on fatty acids or on fatty amines, substituted phenols ( mainly alkylphenols or arylphenols), salts of esters of sulfosuccinic acids, taurine derivatives (mainly alkyl taurates), phosphonic esters of polyoxyethylated alcohols or phenols, esters of fatty acids and polyols, derivatives with groups sulfates, sulfonates and phosphates of the preceding compounds. The presence of at least one surfactant is in general indispensable when the active material and / or the inert carrier are not soluble in water and when the application vector is water.

Thus, the compositions for agricultural use according to the invention can contain the active material in very large limits, ranging from 0.05% to 95% (by weight). Its proportion in surfactant is advantageously between 5% and 40% by weight. Unless otherwise indicated, the percentages given in this description, including the claims, are by weight. These compositions according to the invention are in very diverse forms, solid or liquid. As forms of solid compositions, mention may be made of powders for dusting (a proportion of active material that can go up to 100%) and granules, mainly those obtained by extrusion, by compaction, by impregnation of a support or granulated carrier, by granulation from a powder (the proportion of active material in these granules is between 0.5 and 80% for these latter cases), tablets or effervescent tablets. The fungicidal composition according to the invention can even be used in the form of dusting powders; a composition comprising 50 grams of active material and 950 grams of talc can also be used; a composition comprising 20 grams of active material, -10 grams of finely divided silica and 970 grams of talc; These constituents are mixed and crushed and the mixture is applied by dusting. As forms of liquid compositions or intended to constitute the liquid compositions at the time of application, mention may be made of the solutions, in particular the water-soluble concentrates, the emulsions, the suspensions, the concentrates, the aerosols, the wettable powders (or powder for pulverize), the pastes, _ the gels. The concentrated suspensions, applicable in spray, are prepared in order to obtain a stable fluid product that is not deposited, and these usually contain from 10 to 75% of active material, from 0.5 to 15% of surfactants, from 0.1 to 10% of thixotropic agents, from 0 to 10% of appropriate additives, such as defoamers, corrosion inhibitors, stabilizers, penetrating agents and adhesives and, as a carrier or carrier, water or an organic liquid in which the active material is little or no soluble: certain organic solid materials or mineral salts can be dissolved in the support to help prevent sedimentation or as antigels for water. As an example, here is a concentrated suspension composition: Example SC 1: - active material 500 g - polyethoxylated tristyrylphenol phosphate 50 g - polyethoxylated alkylphenol 50 g - sodium polycarboxylate 20 g - ethylene glycol 50 g - organopolysiloxane oil (inhibitor i g of foam) - polysaccharide 1.5 g - water 316.5 g Wettable powders (or powder for pulverization) are usually prepared so that they contain from 20 to 95% active material, and these usually contain, in addition to the solid support or carrier, from 0 to 30% of a wetting agent, from 3 to 20% of a dispersing agent, and, when necessary, 0.1 to 10% of one or more stabilizers and / or other additives, such as penetrating agents, adhesives, or anticaking agents, dyes, etc. To obtain the powders for spraying or wettable powders, the active materials are intimately mixed in suitable mixers with additional substances and grinded with mills or other suitable grinders. This gives powder for pulverization whose wetting and suspension properties are advantageous; this can be suspended in water at any desired concentration and these suspensions are very advantageously usable in particular for application to the leaves of vegetables. Instead of wettable powders, pastas can be made. The conditions and methods of implementation and use of these pastes are similar to those of wettable powders or powders for pulverizing. By way of example, there are several compositions of wettable powders (or powders to be sprayed): Example PM 1: - active material 50% - ethoxylated fatty alcohol (agent 2.5 = humectant) ethoxylated phenylethylphenol (agent 5% dispersant) gypsum (inert support) 42.5% Example PM 2: - active material 10% - synthetic alcohol oxo of branched type, of 13 carbon atoms ethoxylated with 8 to 10 molecules of ethylene oxide (wetting agent) 0.75% - neutral calcium lignosulfonate (dispersing agent) 12% - calcium carbonate (inert charge) csp 100% Example PM 3: ___ This wettable powder contains the same ingredients as in the previous example, in the following proportions: - active material 75% - wetting agent 1.50% - dispersing agent 8% - calcium carbonate (inert filler) csp 100% Example PM 4: - active material 90% - ethoxylated fatty alcohol (wetting agent) 4% - ethoxylated phenylethylphenol (dispersing agent) 6% Example PM 5: - active material 50% - mixture of anionic and nonionic surfactants (wetting agent) 2.5% - sodium lignosulfonate (dispersing agent) 5% - kaolin clay (inert support) 42.5% The aqueous dispersions and emulsions, for example the compositions obtained by diluting a wettable powder or an emulsifiable concentrate according to the invention with the aid of water, fall within the general framework of the present invention. The emulsions may be of the water-in-oil or oil-in-water type and these may have a thick consistency such as that of a 'mayonnaise. "The fungicidal compositions according to the invention may be formulated in the form of water-dispersible granules, Within the scope of the invention, these dispersible granules, having an overall density of between approximately 0.3 and 0.6, have a particle size in general between approximately 150 and 2000 and preferably between 300 and 1500 microns. of these granules is in general between about 1% and 90%, and preferably between 25% and 90% The rest of the granulate is essentially composed of a solid filler and possibly of surfactant adjuvants which give the granulate dispersibility properties in the granules. These granules can be essentially of two different types depending on whether the load is da is soluble or not in water. When the charge is water-soluble, it may be mineral or, preferably, organic. Excellent results have been obtained with urea. In the case of an insoluble filler, it is preferably mineral, such as, for example, kaolin or bentonite. This is then advantageously accompanied by surfactants (at a ratio of 2 to 20% by weight of the granulate) where more than half is, for example, constituted by at least one dispersing agent, essentially anionic, such as an alkali or alkaline earth metal polytalphthalenesulfonate or a alkali metal or alkaline earth metal lignosulfonate, the rest being constituted by nonionic or anionic wetting agents such as an alkali metal or alkaline earth metal alkylnaphthalenesulfonate. On the other hand, although this is not indispensable, other adjuvants such as foam anti-foaming agents can be added. The granulate according to the invention can be prepared by mixing the necessary ingredients after the granulation according to several techniques known per se (drageoir, fluidized bed, atomizer, extrusion, etc.). It is generally finished by means of a grinding followed by a sieving to the chosen particle size in the limits chosen above. It is also possible to use the granules obtained as described above and then impregnated with a composition containing the active material. Preferably, this is obtained by extrusion, operating as indicated in the following examples: Example GDI: Dispersible granules In a mixer, 90% by weight of the active material and 10% of urea are mixed into beads. The mixture is then crushed in a spindle grinder. A powder is obtained which is humidified with approximately 8% by weight of water. The wet powder is extruded in a perforated roller extruder. A granulate is obtained which is dried, then crushed and sieved, so as not to store more than the granules of a dimension comprised between 150 and 2000 microns respectively.

Example GD2: Dispersible granules In a blender, the following constituents are mixed: - active material 75% - wetting agent (sodium alkylnaphthalene sulfonate) 2% - dispersing agent (sodium polynaphthalene sulfonate) 8% - water insoluble inert filler (kaolin) 15% This mixture is granulated in a fluidized bed, in the presence of water, then dried, crushed and sieved in order to obtain granulates with a dimension comprised between 0.15 and 0.80 mm. These granules can be used alone, in solution or dispersion in water in order to obtain the desired dose. These can also be used to prepare combinations with other active materials, mainly fungicides, the latter being in the form of wettable powders, or of granules or aqueous suspensions. As far as the compositions adapted to storage and transport are concerned, they more advantageously contain 0.5 to 95% (by weight) of active material. Another object of the invention is a method for combating, in a curative or preventive manner, the phytopathogenic fungi of crops, characterized in that an effective and non-phytotoxic amount of a combination is applied on the aerial parts of the plants or on the soil. of compound A and at least one compound B, for example in a fungicidal composition according to the invention.

The phytopathogenic fungi of crops that can be combated by this process are mainly those: from the group of oomycetes: from the genus Phytophthora such as Phytophthora phaseoli, Phytophthora citrophthora, Phyt oph th ora capsici, Phytophthora cactorum, Phyt oph th ora palmivora, Phytophthora cinnamoni, Phytophthora megasperma, Phytophthora parasitica, Phytophthora fragariae, Phytophtohra cryptogea, Phytophthora porri, Phytophthora nicotianae, Phytophthora infestans; of the Peronosporáceas family, mainly Plasmopara viticola (grape mold), Plasmopara halstedei (sunflower mold), Pseudoperonospora sp (mainly Cucurbitaceae mold) (and Pseudoperonospora humili), Bremia lactucae (mold of lettuce), Peronospora tabacinae (mold of tobacco), Peronospora destructor (mold of the cruciferae), Peronospora parasitica (mold of cabbage), Peronospora farinosa (mold of endives and mold of beet). The crops considered in the framework of the present invention are preferably legume crops (beans, onions, cucurbits, cabbage, potatoes, tomatoes, peppers, spinach, peas, lettuce, endives), fruit crops (strawberries, raspberries), the tree crops (apples, pears, ginseng, citrus fruits, coconut trees, cocoa, heveas, bananas), the vine, the sunflower, the beet, the tobacco and the ornamental crops. The fungicidal composition object of the invention is applied by means of different treatment methods such that: the spraying on the aerial parts of the crops to be treated, with a liquid comprising said composition; - dusting, the incorporation into the soil of granules or powders, irrigation, injection into trees or daubing. Spraying a liquid on the aerial parts of crops to be treated is the preferred treatment method. By "effective and non-phytotoxic amount" is meant an amount of composition according to the invention sufficient to allow the control or destruction of the fungi present or likely to appear on the crops, and which does not involve any notable symptom for said crops. Such an amount is capable of varying in large limits according to the fungus to be controlled, the type of crop, the climatic conditions, and the compounds comprised of the fungicidal composition according to the invention.This amount can be determined by tests systematic in field, within the reach of the expert in the field.The doses of employment at the time of putting into operation the procedure according to the invention are generally given then on the vine, legume crops, arboriculture, citrus, etc. : by foliar treatment: from 500 to 6000 g / ha of compound B, for example fosetyl-Al, + 500 to 6000 g / ha of compound A and more precisely from 1000 to 3000 g / ha + 1000 to 3000 g / ha, or a total dose of the composition according to the invention comprised between 1000 and 12000 g / ha, preferably between 2000 and 6000 g / ha. Preferably, a total dose of composition according to the invention is used equal to 3000 g / ha, or 1500 g / ha of compound A + 1500 g / ha of compound B. By soil treatment (irrigation): 25 to 300 kg / ha of compound B, for example fosetyl-Al, + 25 to 300 kg / ha of compound A and more precisely of 50 to 150 kg / ha + 50 to 150 kg / ha, or a total dose of the composition according to the invention comprised between 50 and 600 kg / ha, preferably between 100 and 300 kg / ha. Preferably, a total dose of composition according to the invention is used equal to 200 kg / ha, or 100 kg / ha of compound A + 100 kg / ha of compound B. The following examples are given purely by way of illustration. of the invention, which do not limit it in any way.

Example 1: Vineyard trial The tested fungicides are the following: Aliette P: formulation P containing 80% of fosetyl-Al / kg, Prévicur N: formulation SL containing 772 g of propamocarb / 1.

The tested fungicidal compositions are the following: Aliette at the doses of 62, 125, 250, 500, 1000, 2000 and 4000 ppm of active material (m.a.). Prévicur N at the doses of 62, 125, 250, 500, 1000, 2000 and 4000 ppm of m.a. Aliette + Prévicur at the doses of 125 + 62, 250 + 125, 500 + 250, 1000 + 500, 2000 + 1000 and 4000 + 2000 ppm of m.a. (ratio 2/1). Aliette + Prévicur at the doses of 125 + 125, 250 + 250, 500 + 500, 1000 + 1000, 2000 + 2000 and 4000 + 40000 ppm of m.a. (1/1 ratio).

The vine plants (Chardonay variety) of 8 weeks are treated with the fungicidal compositions at the doses mentioned above (3 repetitions / doses). One day after the treatment, the plants are contaminated by an aqueous suspension containing 100,000 spores of Pl a smopara vi ti col a / ml of inoculum. The plants are then placed in a climatic cell at 20 ° C, and 100% RH (relative humidity) for 9 days. An observation is then made. This consists of estimating the proportion of the diseased plant for each test factor and, for comparison to an untreated-contaminated control, to define the percentage of efficacy according to the following formula: Practical efficiency% = 100 x (% of Control contamination -% of Test contamination) /% of Control contamination.

The theoretical efficiency according to Colby's formula is calculated according to the following formula: % of theoretical effectiveness A + B =% of practical effectiveness A +% of practical effectiveness B - (% of practical effectiveness A x% of practical effectiveness B / 100) Practical efficiency (Observed: Prévicur (ppm) 62 125 250 500 1000 2000 4000 0 12 12 21 39 62 0 Aliette 125 0 (ppm) 250 9 12 500 18 21 29 1000 54 54 70 2000 68 79 100 4000 91 96 100 Theoretical effectiveness (according to Colby) Prévicur (ppm; 62 125 250 500 1000 2000 4000 0 12 12 21 39 62 0 Aliette 125 0 (ppm) 250 9 20 500 18 28 22 1000 54 56 60 2000 68 72 75 4000 91 93 95 Synergy values Prévicur (ppm) 62 125 250 500 1000 2000 4000 0 12 12 21 39 62 0 Aliette 125 0 (ppm) 250 9 +3 -16 500 18 +7 1000 54 -2 +10 2000 68 +7 +25 4000 91 +3 +5 It shows a good synergistic relationship Example 2: Test on cabbage The experienced fungicides are the following: Aliette WP: formulation of WP containing 80% of fosetyl-Al / kg. Prévicur N: SL formulation containing 722 g of propamocarb / 1.

The tested fungicidal compositions are the following: Aliette at the doses of 125, 250, 500, 1000, 2000, 4000 and 8000 ppm of active material (m.a.). Prévicur N at doses of 125, 250, 500, 1000 and 2000 ppm of m.a.

Aliette + Prévicur at doses of 500 + 125, 1000 + 250, 2000 + 500, 4000 + 1000 and 8000 + 2000 ppm of m.a. (proportion (4/1) Aliette + Prévicur at doses of 250 + 125, 500 + 250, 1000 + 500, 2000 + 1000 and 4000 + 2000 ppm of m.a. (ratio 2/1). Aliette + Prévicur at doses of 125 + 125, 250 + 250, 500 + 500, 1000 + 1000 and 2000 + 2000 ppm of m.a. (1/1 ratio).

Cabbage plants (Cabus de Brunswick variety) of 10 days old are treated by the fungicidal compositions at the doses indicated above (3 repetitions / doses). One day after the treatment, the flat ones are contaminated with an aqueous suspension containing 50,000 spores of Peronospora parasitica / ml of inoculum. The plants are then placed in a climatic cell at 15 ° C, 100% RH (relative humidity) for 6 days. An observation is made. This consists in estimating the proportion of the sick plant for each test factor and, by comparison to an untreated-contaminated control, in defining the efficiency percentage according to the following formula:% practical efficiency = 100 x (% of Witness contamination -% of contamination test) /% contamination Witness.

The theoretical efficiency according to the Colby formula is calculated according to the following formula: % theoretical efficiency A + B = practical efficiency% A +% - practical effectiveness B - (% practical efficiency A x% practical efficiency B / 100).

Practical effectiveness (observed): Prévicur (ppm) 0 125 250 500 1000 2000 0 0 7 17 73 94 Aliette 125 0 0 (ppm) 250 0 0 60 500 0 3 20 87 1000 0 53 73 97 2000 20 87 95 100 4000 47 98 99 8000 83 100 Efficacy theoretical (according to Colby) Prévicur (ppm) 0 125 250 500 1000 2000 0 0 7 17 73 94 Aliette 125 0 0 (ppm) 250 0 0 7 500 0 0 7 17 1000 0 7 17 73 2000 20 34 78 95 4000 47 89 97 8000 83 99 Synergy values: Prévicur (ppm) 0 125 250 500 1000 2000 0 0 7 17 73 94 Aliette 125 0 0 (ppm) 250 0 0 +53 500 0 +3 +13 +70 1000 0 +46 +56 +24 2000 20 +53 +17 +5 4000 47 +12 +2 8000 83 +1 It shows a good synergistic relationship.

Example 3: Test on potato The experienced fungicides are the following: Aliette WP: WP formulation containing 80% fosetyl-Al / kg. Prévicur N: formulation SL that contains 722 g of propamocarb / 1.

The tested fungicidal compositions are the following: Aliette at the doses of 500, 1000, 2000, 4000 and 8000 ppm of active material (m.a.). Prévicur N at the doses of 62, 125, 250, 500, 1000, 2000 and 4000 ppm of m.a.

Aliette + Prévicur at the doses of 500 + 125, 1000 + 250, 2000 + 500, 4000 + 1000 and 8000 + 2000 ppm of m.a. (proportion (4/1).

Aliette + Prévicur at the doses of 500 + 250, 1000 + 500, 2000 + 1000, 4000 + 2000 and 8000 + 4000 ppm of m.a. (ratio 2/1). Aliette + Prévicur at the doses of 500 + 500, 1000 + 1000, 2000 + 2000 and 4000 + 4000 ppm of m.a. (1/1 ratio).

The potato plants (variety Bintge) of 3 weeks of age are treated with the fungicidal compositions at the doses mentioned above (2 repetitions / doses). One day after the treatment, the plants are contaminated with an aqueous suspension containing 30,000 spores of Phyt oph t ora infes tans (strain F4.95) / ml of inoculum. The plants are then placed in a climatic cell at 10 ° C, 100% RH (relative humidity) for 5 days. These are then tranred to 15 ° C for 4 additional days, and are finally placed in a greenhouse at 20 ° C, 100% RH for 2 additional days. An observation is then made. This consists in estimating the proportion of sick plant for each test factor, and by comparison to an untreated-contaminated control, in defining the percentage of efficacy according to the following formula:% practical efficiency = 100 x (% of contamination) Control -% contamination Test) /% contamination Control.

The theoretical efficiency according to the Colby formula is calculated after the following formula: % of theoretical effectiveness A + B =% of practical effectiveness A +% of practical effectiveness B - (% of practical effectiveness A x% of practical effectiveness B / 100).

Results Practical effectiveness (observed) * Pr évi cur (ppm) 0 62 125 250 500 1000 2000 4000 0 0 0 0 20 20 45 500 0 10 0 0 Aliette 1000 0 10 0 10 (ppm) 2000 0 15 5 30 4000 0 15 25 60 8000 15 25 40 Theoretical efficiency (according to Colby) Prévicur (ppm) 62 125 250 500 1000 2000 4000 0 0 0 20 20 45 500 0 0 0 0 Aliette 1000 0 0 0 20 (PPm) 2000 0 0 20 20 4000 0 20 20 45 80D0 15 32 53 Synergy values Prévicur (ppm) 62 125 250 500 1000 2000 4000 0 0 0 0 20 20 45 500 0 +10 0 0 Aliette 1000 0 +10 0 -10 (ppm) 2000 0 +15 -15 +10 4000 0 -5 +5 +15 8000 15 +7 -13 A synergistic relationship is observed It is noted that in relation to this date, the best method known to the applicant to carry out the aforementioned invention, is that which is clear from the present description of the invention.

Claims (11)

CLAIMS Having described the invention as above, the content of the following claims is claimed as property:

1. The synergistic fungicidal composition comprising as compound A the propamocarb and at least one fungicidal compound B chosen from the group comprising the phosphorous acid derivatives such as the metal phosphites such as the fosetyl-Al, and the phosphorous acid itself and its alkali or alkaline earth salts; said composition, characterized in that it contains the components A and B in a proportion by weight A / B comprised between 1/12 and 12/1, preferably 1/3 and 3/1.

2. The fungicidal composition according to claim 1, characterized in that the compound B is the fosetyl Al.

3. The fungicidal composition according to any of claims 1 to 2, characterized in that preferably, the composition is not applied on the lawn.

4. The fungicidal composition according to any of claims 2 or 3, characterized in that the ratio A / B is between 1/3 and 3/1, and even more advantageously this ratio is equal to 1 for the set of crops considered .

5. The fungicidal composition according to any of claims 1 to characterized in that it comprises the compounds A and B in admixture with the solid or liquid carriers acceptable in agriculture, and / or the surfactants equally acceptable in agriculture.

6. The fungicidal composition in accordance < r with any of claims 1 to ß, characterized in that it comprises from 0.05 to 95% (by weight) of active material.

7- A method of control of phytopathogenic fungi of a medium, characterized in that a compound A and at least one compound B are applied to said medium, these compounds being as defined in claim 1, and the combination of these compounds is in a total amount effective and not phytotoxic.

8 * A method of fighting, curatively or preventively, against phytopathogenic fungi of crops, characterized in that an effective and non-phytotoxic amount of a fungicidal composition is applied on the aerial parts of the plants or on the soil in accordance with any of the claims 1 to 6.

9 > The control method according to claim 8, characterized in that a liquid comprising the fungicidal composition according to any of claims 1 to 7 is sprayed onto the aerial parts of the crops to be treated.

10. The method for controlling phytopathogenic fungi of crops according to claim 9, characterized in that a total dose of the composition comprised between 1,000 and 12,000 g / ha, preferably between 2,000 and 6,000 g / ha, is applied by foliar treatment.

11. . The process according to claim 12, characterized in that a total dose of the composition equal to 3,000 g / ha is applied. 8, The method of control against phytopathogenic fungi of crops according to claim 13? characterized in that a total composition dose between 50 and 600 kg / ha, preferably between 100 and 300 kg / ha, is applied to the soil. 1? The control method according to claim 14, characterized in that a total composition dose equal to 200 kg / ha is applied. . A product comprising at least one compound A and at least one compound B for the control of phytopathogenic fungi of a medium, by simultaneous, sequential or separate application.