MXPA06010105A - Pesticidal composition and method for seed treatment - Google Patents

Abstract

The present invention provides an at least binary composition for controlling nematodes and insects or representatives of the order Acarina, which composition comprises:(A) a nernaticidally effective amount of at least one macrolide, and (B) an insecticidally effective amount of at least one insecticide selected from the neonicotinoids.

Description

PESTICIDE COMPOSITION AND METHOD FOR TREATMENT OF SEEDS FIELD OF THE INVENTION The present invention relates to a pesticidal composition that is suitable for controlling nematodes and insects and / or representatives of the order Acariña, comprising (a) at least one nematicide and (b) at least one insecticide. The pesticidal composition is particularly suitable for the protection of plant propagation materials such as seeds.

BACKGROUND OF THE INVENTION Some mixtures of active ingredients for the control of pests have been described in the literature. The biological properties of these known mixtures are not entirely satisfactory, for example, in the areas of nematode control, phytotoxicity, load indexes and environmental and worker exposure. The protection of plant propagation materials (seed treatments) with pesticides are white applications that partially address the need for a reduction in environmental exposure and workers when used alone or in combination with foliar pesticide applications or the groove. However, there is also a need to present other mixtures that reduce the need for REF pesticides. : 174776 acutely toxic and reduce load rates. Among the older nematicides, the following may be mentioned: methyl bromide, sodium metam, carbophuric etopróp, aldicarb, fenamifos and oxamyl. Accordingly, there is a need to produce pesticidal compositions, in particular compositions that are used as treating compositions of the plant propagation material, and methods for the protection of plant propagation materials, especially compositions having improved biological properties, for example synergistic pesticidal properties, especially for the control of nematodes and insects. This problem is solved according to the present invention by presenting the present pesticidal composition.

BRIEF DESCRIPTION OF THE INVENTION The present invention presents a composition for combating nematodes and insects and / or representatives of the order Acariña, composition comprising: (A) at least one active macrolide compound as nematicide and (B) at least an active compound as an insecticide selected from neonicotinoids. More specifically, the present invention presents a composition for the control of nematodes and insects and / or representatives of the Acariña order, which is especially suitable for the protection of plant propagation materials such as crop seeds. The pesticidal composition of the present invention comprises: (A) an effective nematicide amount of at least one macrolide compound and (B) an insecticidally effective amount of at least one insecticidal compound selected from the neonicotinoids. The invention also relates to a process for the protection of propagation materials of plants and plants produced therefrom against nematodes and fungal diseases by the use of a pesticidal composition according to the present invention. It is also related to the aforementioned propagation materials of plants coated with the pesticidal composition. The present invention provides the possibility of coating or treating seeds and other plant propagation materials with smaller amounts of the acutely toxic old biocides than is known in the prior art and, in most cases, replacing the old biocides acutely toxic; therefore, the invention represents a considerable contribution to the art.

DETAILED DESCRIPTION OF THE INVENTION Nematicidal Compound (A) The pesticidal compositions according to the invention comprise an active ingredient such as nematicide (A) comprising at least one macrolide compound selected from abamectin, emamectin benzoate and spinosad. Abamectin is a preferred macrolide compound (A). Abamectin is known, for example, from The Pesticide Manual, llth Ed. (1997). The British Crop Protection Council, London, page 3. The emamectin benzoate is known, for example, from e-Pesticide Manual, version 3 .0, 13th Edition, Ed. CDC Tomlin, British Crop Protection Council, 2003-04. entry 291; and The spinosad is known, for example, from the e-Pesticide Manual, version 3 .0, 13 th Edition, Ed. CDC Tomlin, British Crop Protection Council, 2003-04, entry 737.

Insecticide Component (B) The pesticidal compositions according to the present invention comprise, as an ingredient with insecticidal activity (B): at least one insecticidal compound selected from (Bl) imidacloprid, (B2) clothianidin and (B3) thiamethoxam. Imidacloprid is known, for example, from the e-Pesticide Manual, version 3. 0, 13 th Edition, Ed. CDC Tomlin, British Crop Protection Council, 2003-04, entry 458.

Clothianidin is known, for example, from the e-Pesticide Manual, version 3.0, 13th Edition, Ed. CDC Tomlin, British Crop Protection Council, 2003-04, entry 165; _- and Thiamethoxam is known, for example, from the -Pesticide Manual, version 3.0, 13th Edition, Ed. CDC Tomlin, British Crop Protection Council, 2003-04, entry 792.

Combination of I.A. It has been found, with surprise, that the combination of at least one nematicidal active ingredient (A) with at least one insecticidal active ingredient selected from (Bl), (B2) and (B3) gives rise to an astonishingly enhanced action against nematodes and insects and / or which provides other unexpected advantages when used in connection with plant propagation materials. The increase in action and / or other advantageous properties obtained with the combination according to the present invention is considerably greater than the activity that can be expected from the individual components, ie the activity is enhanced synergistically, which, among other things it extends the limits of the pesticide activity of the compounds. The mixture of the invention is particularly suitable for coating applications of plant propagation material. This last term covers seeds of all kinds (fruits, tubers, grains), cuttings, cuttings and the like. Seeds are preferred. A specific field of application is the treatment of all types of silage, in particular the treatment of cotton seeds, of fruit vegetables such as tomatoes and peppers, cucurbit vegetables such as melons, cantaloupe, pumpkins and cucumbers. In addition to the mixture of at least two components, the invention further relates to a method for controlling insects and nematodes, which comprises the treatment of a site, for example a plant or a plant propagation material (especially the seed) , that is infested or is prone to be infested by insects and nematodes with: (1) at least one active ingredient. nematicide (A) and (2) at least one insecticidal active ingredient (B) in any convenient order or simultaneously. The nematicidal active ingredient is generally applied in a mixed weight ratio (A): (B) from 1: 5 to 5: 1. For example, in one embodiment, a nematicide such as abamectin (A) is applied in a proportion of 100 g - 400 g of ia / 100 kg of seeds and an insecticide such as a neonicotinoid (B) in a proportion of 300 g - 500 g of ia / 100 kg of seeds. As a specific example, abamectin is applied in a proportion of 100 g / 100 kg of seeds. In one embodiment, abamectin is applied at a rate of 0.1 to 0.15 mg / seeds or, in particular, 0.1 mg / seed. In particular, it has now been found, with surprise, that at least the pesticidal activity of the compositions according to the present invention, in comparison with the pesticidal activity of the individual components, is not merely additive, as would be expected, but there is a synergistic effect. The term "synergistic" is in no way limited, in this context, to pesticidal activity, but also refers to other advantageous properties of the compositions according to the present invention as compared to the individual components. Examples of the advantageous properties that may be mentioned are: an extension of the spectrum of pesticidal activity against other pests, for example resistant strains; a reduction in the application rate of the active ingredients; adequate control of the pests with the aid of the compositions according to the present invention, even at an application rate at which the individual compounds are totally ineffective; advantageous behavior during the formulation and / or after the application, for example after grinding, sieving, emulsification, dissolution or. dispersion; increased stability in storage; improved stability to light; more advantageous degradation capacity, improved toxicological and / or ecotoxicological behavior; improved cultivation characteristics, which include: emergence, crop yields, plant size, more developed root system, increase of the tiller, increase in the height of the plants, greater width of the leaf, lower quantity of dead basal leaves, stronger clusters, greener foliar color, less need for fertilizers, less necessary seeds, more productive tillers, earlier flowering, early maturity of the grains, less overturning (incarnation) of the plants, growth of the improved buds, improved vigor of the plants and early germination, or any other advantage which is familiar to a person skilled in the art. The combination of active ingredients used in the seed treatment composition according to the present invention preferably comprises abamectin and thiamethoxam in a ratio of 100-400 g of abamectin / 100 kg of seeds at 300 g -500 g of thiamethoxam / 100 kg of seeds. In one embodiment, at least one antimicrobial active substance (C) (also known as a fungicide) is used with the mixture of at least two components (A) and (B) in order to increase the spectrum of action or to obtain effects such as, for example, producing fungicidal control. Suitable classes of fungicides include phenylamides, phenylpyrroles, strobilurins and triazoles.

In one embodiment, the composition for treating seeds and the method (or methods) of the present invention is combined with one or more foliar insecticidal and / or fungicidal treatments and / or in the furrow. Suitable insecticides include, for example, Temik® (aldicarb), thiamethoxam, imidacloprid and clothianidin. Suitable fungicides include metalaxyl, R-metalaxyl, the estobilurins such as azoxystrobin, the triazoles such as myclobutanil, fludioxonil, triadimenol, TCMTB, PCNB, carboxin and chloroneb.

Insect Pests The compositions of the present invention can be used for the protection of propagation material of plants and plants in development against animal pests such as insects and representatives of the Acariña order, including: from the order of the Lepidoptera, by Examples: Acleris spp., Adoxophyes spp., Aegeria spp., Agrotis spp., Alabama argillaceae, Amylois spp., Anticarsia gemmatalis, Archips spp., Argyrotaenia spp., Autographa spp., Busseola fusca, Cadra cautella, Carposina nipponensis, Chilo spp., Choristoneura spp., Clysia ambiguella, Cnaphalocrocis spp. Cnephasia spp., Cochylis spp., Coleophora spp., Crocidolomia binotalis, Cryptophlebia leucotreta, Cydia spp., Diatraea spp., Diparopsis castanea, Earias spp., Ephestia spp., Eucosma spp., Eupoecilia ambiguella, Euproctis spp., Euxoa spp., Grapholita spp., Hedya nubiferana, Heliothis spp., Hellula undalis, Hyphantria cunea, Keiferia Iycopersicella, Leucoptera scitella, Lithocollethis spp., Lobesia botrana, Lymantria spp., Lyonetia spp., Malacosoma spp., Mamestra brassicae, Manduca sexta , Operophtera spp., Ostrinia nubilalis, Pammene spp., Pandemis spp., Panolis flammea, Pectinophora gossypiella, Phthorimaea sperculella, Pieris rapae, Pieris spp., Plutella xylostella, Prays spp., Scirpophaga spp., Sesamia spp., Sparganothis spp. , Spodoptera spp., Synanthedon spp., Thaumetopoea spp., Tix spp., Trichoplusia ni and Yponomeuta spp .; of the order of the Coleoptera, for example, Agriotes spp., Anthonomus spp., Atomaria linearis, Chaetocnema tibialis, Cosmopolites spp., Curculio spp., Dermestes spp., Diabrotica spp., Epilachna spp., Eremnus spp., Leptinotarsa decemlineata, Liásorhoptrus spp., Melolontha spp., Orycaephilus spp., Otiorhynchus spp., Phlyctinus spp., Popillia spp., Psylliodes spp., Rhizopertha spp., Scarabeidae, Sitophilus spp., Sitotroga spp., Tenebrio spp., Tribolium spp. and Trogoderma spp .; of the order of the opterans, for example, Blatta spp., Blattella spp., Gryllotalpa spp., Leucophaea maderae, Locusta spp., Periplaneta spp., and Schistocerca spp .; of the order of the Isoptera, for example, - Reticulitermes spp .; of the order of the Psocópteros, for example Liposcellis spp.; of the order of the Anoplura, for example, Haematopinus spp., Linognathus spp., Pediculus spp., Pemphigus spp. and Phylloxera spp .; of the order Mallophaga, for example, Damalinea spp. and Trichodectes spp .; of the order of the Thysanoptera, for example Frankliniella spp., Hercinothrips spp., Taeniothrips spp., Thrips pal i, Thrips tabaci and Scirtothrips aurantii; of the order of the Heteroptera, for example, Cimex spp., Distantiella theobroma, Dysdercus spp., Euchistus spp., Eurygaster spp., Leptocorisa spp., Nezara spp., Pies a spp., Rhodnius spp., Sahlbergella singularis, Scotinophara spp. . and Triatoma spp .; of the order of the Homoptera, for example, Aleurothrixus floccosus, Aleyrodes brassicae, Aonidiella spp., Aphididae, Aphis spp., Aspidiotus spp., Bemisia tabaci, Ceroplaster spp., Chrysomphalus aonidium, Chrysomphalus dictyospermi, Cocsus hesperidum, Empoasca spp., Eriosoma larigerum, Erythroneura spp., Gascardia spp., Laodelphax spp., L.ecanium corni, Lepidosaphes spp., Macrosiphus spp., Myzus spp., Nephotettix spp., Nilaparvata spp., Paratoria spp., Pemphigus spp., Planococcus spp., Pseudaulacaspis spp., Pseudococcus spp., Psylla spp., Pulvinaria aethiopica, Quadraspidiotus spp., Rhopalosiphum spp., Saissetia spp., Scaphoideus spp., Schizaphis spp., Sitobion spp., Trialeurodes vaporariorum, Trioza erytreae and Unaspis citri; from the order Hymenoptera, for example, Acromyrmex, Atta spp., Cephus spp., Diprion spp., Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium pharaonis, Neodiprion spp., Solenopsis spp., and Vespa spp. .; from the order of Diptera, for example, Aedes spp., Antherigona soccata, Bibio hortulanus, Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp., Cuterebra spp., Dacus spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Glossina spp., Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza spp., Musca spp., Oestrus spp., Orseolia spp., Oscinella frit, Pegomyia hyoscyami, Phorbia spp., Rhagoletis po onella, Sciara spp., Stomoxys spp., Tabanus spp., Tannia spp. and Typula spp .; of the order of the siphonaptera, for example Ceratophyllus spp. and Xenopsylla cheopis and the order of the thysanides, for example, Lepisma saccharina.

Nematode Pests Among the representative examples of the Nematoda class that can be combated by means of the compositions of the present invention are, for example, the nematodes of the eelworm or root rot, the trunk nematodes and the foliar nematodes; .especially Heterodera spp. , for example Heterodera schachtii, Heterodora avenae and Heterodora trifolii; Hoplolaimus spp. such as Hoplolaimus galeatus and Hoplolaimus columbus; Globodera spp., For example Globodera rostochiensis; Meloidogyne spp. , for example Meloidogyne incoginita and Meloidogyne javanica; Radopholus - spp. , for example Radopholus similis; Rotylenchulus spp. such as R. reniformis; Pratylenchus spp. , for example Pratylenchus neglectans and Pratylenchus penetrans; Tylenchulus spp. , for example Tylenchulus semipenetrans; Belonolaimus spp.; Longidorus spp.; Trichodorus spp.; Xiphinema spp.; Ditylenchus spp.; Aphelenchoides spp. and Anguina spp.; especially Meloidogyne spp. , for example Meloidogyne incognita, and Heterodera spp. , for example Heterodera glycines.

White Crops White crops within the scope of the present invention are, for example, the following plant species: beet (sugar beet and fodder beet), oil plants (cañola, rapeseed, mustard seeds, poppy, olive, sunflower, coconut, Castor oil plants, cocoa pods, peanuts and soybeans). Peanuts, sorghum wheat, cotton, corn, soybeans, tobacco, cabbage, cabbages, onions and carrots are also suitable. The present invention includes potatoes, mint, forage grasses and hay, as well as the subgroup of fine grasses, In addition, the crops cited in the tables of culture groups in 40 CFR Sec. 180.41 (1995). 180.41 (1995) and the Federal Register: May 17, 1995 (vol 60, no.95) pp. 26625-26643 are hereby incorporated by reference in their entirety for information regarding crop plants: ( 1) Crop Group 5: Group of Brass Leaf Vegetables (Coles), for example broccoli, cauliflower, cabbage; and leaf mustard; (2) Growing Group 9: Group of cucurbit plants, for example cucumber, melons, cantaloupe, muskmelon melons, pumpkins, incl. zucchini; (3) Crop Group 11: Group of pip fruits; for example apple and pear; (4) Grow Group 15: Group of cereal grains, eg corn and rice. You can also mention the fruit vegetables, for example tomatoes and peppers. The following plants should be considered white cultures especially suitable for the at least binary pesticidal compositions (e.g., abamectin and thiamethoxam) of the present invention; propagation materials of plants (such as seeds) of oil plants (cañola, rapeseed, mustard seeds, poppy, olive, sunflower, coconut, castor oil plants, cocoa beans and peanuts). White crops and seeds treated in accordance with the present invention include conventional varieties as well as genetically improved or modified varieties such as, for example, insect resistant varieties (e.g., Bt. And VIP varieties), as well as resistant to diseases, tolerant to herbicides and tolerant to nematodes. By way of example, among the suitable genetically improved or modified crop varieties are, for example, Stoneville 5599BR and Stoneville 4892BR cotton.

Treatment of seeds The pesticidal composition according to the present invention has proven to be especially advantageous for the protection of seeds, especially cottonseeds, fruit vegetables, including tomatoes and peppers, cucurbit vegetables, including melons, cantaloupe , pumpkins and cucumbers. However, the composition of the present invention is also suitable for the direct treatment of soil or other parts of the plant. The composition of the present invention is well tolerated by plants and is acceptable from the ecological point of view.

The subject of the invention is also a method to protect the products - from the multiplication of plants (propagation materials of plants) and the plants that emerge from them, against nematodes and fungal diseases, by which these products are coated for multiplication with a nematicidal and insecticidal composition and 'Substantially non-phytotoxic, containing a fungicide. Usually, the at least binary pesticidal composition according to the present invention is employed together with the usual adjuvants in the formulation technology. The combination of the active ingredients (A) and at least one of (Bl), (B2) and (B3) are normally applied to the propagation material of plants in the form of compositions, although it can also be applied to the seeds or to the locus of propagation of the same (as, for example, to a groove), simultaneously or successively, with other compounds. These other compounds can be fertilizers or donors of miero-nutrients or other preparations that influence the growth of plants. They can also be herbicides, insecticides, fungicides, selective bactericides, regulators of insect development, plant growth regulators, foliar nematocides or applied to the soil, molluscicides or mixtures of several of these preparations, "" if appropriate, together with other vehicles, surfactants or application-promoting adjuvants commonly employed in the formulation art. In addition, inoculants7 brighteners and polymers can be mentioned. Also, the present invention includes compositions suitable for agriculture for combating nematodes or insects on or in the seed, consisting essentially of at least a binary pesticidal composition according to the present invention plus a suitable inert surfactant or a liquid or solid carrier. suitable. In the present context, the phrase "consisting essentially of" does not exclude the presence of other pesticidal materials or conventional formulation ingredients. The active components (A) and at least one of (Bl), (B2) and (B3) are processed in the known manner to give, for example, emulsifiable concentrates, suspoemulsions, spreads, spray solutions directly or dilute, dilute emulsions, wettable powders, soluble powders, dusting agents, granules, and also for encapsulation, for example in polymeric substances or in the form of so-called tank mixtures, which are prepared by correspondingly diluting the components formulated separately with water, immediately before the application. The methods of application, such as the application by irrigation, fumigation, atomization, volleying, brushing or spreading and the nature of the composition, are adapted to satisfy the intended purposes and the prevailing circumstances. The optimal application rates of the composition of the present invention for a specific white nematode and a series of insect pressure conditions can be determined easily and without undue experimentation, by simple classification studies carried out in greenhouse or open field . In general, favorable application rates are from 0.05 to no more than 1 kg, especially 0.1-0.5 kg, more specifically 0.3-0.5 kg of each active ingredient (Bl), (B2) and (B3) per 100 kg of the propagation material that is. has to protect. With respect to the active ingredient (A), the favorable application rates can be in the range of 0.005 to no more than 0.8 kg, especially 0.01-0.5 kg, more specifically 0.1-0.4 kg per 100 kg of the propagation material to be protected . However, the application conditions depend essentially on the nature (surface area, consistency, moisture content) of the material and its environmental factors. Consequently, within these intervals, those skilled in the art choose, based on their general knowledge and, if appropriate, a few experiments, doses that are not phytotoxic but effective from the point of view of insecticidal and / or nematicidal activity. It is understood that the term "plant propagation material" indicates all the generating parts of the plant, such as seeds, which can be used for the multiplication of the latter and the material of vegetative plants such as cuttings and tubers (e.g. ). We can mention, for example, the seeds (in the strict sense), roots, fruits, tubers, bulbs, rhizomes, parts of plants. You can also mention the germinated plants and young plants that must be transplanted after germination or after the emergence of the soil. These young plants can be protected before transplanting by means of a total or partial immersion treatment. Techniques for applying the treatment to the seeds are well known to those skilled in the art, and can be easily used in the context of the present invention. The active ingredients can be formulated and applied in the form of a suspension, a solid coating of seeds, soaking or in a powder form on the surface of the seed. It can also be mentioned, for example, the coating in the form of film or encapsulation. The coating processes are well known in the art and employ, in the case of seeds, the techniques of film coating or encapsulation or, in the case of other products for multiplication, immersion techniques. the method of applying the compounds to the seed may vary and the invention must include any technique that may be used .. A preferred method for applying the mixture according to the present invention is to spray or moisten the plant propagation material with a liquid preparation, or mixing the plant material with a solid preparation of the active ingredients The compounds of the present invention can be formulated or mixed in the seed treatment range or combined on the seed by applying a top coat with other top dressing agents. seed treatment The agents to be mixed with the compounds of the present invention may be for pest control, for the modification of growth, nutrition or to fight plant diseases.

Formulations The formulations, ie the compositions, preparations or combinations containing the active ingredients (A) and (Bl), (B2) and / or (B3), as well as, where appropriate, solid or liquid vehicles suitable inerts are prepared in a known manner, for example by intimately mixing and / or grinding the active ingredients with inert diluents acceptable for agriculture, for example with solid or liquid carriers and, if appropriate, surface-active compounds (surfactants). These compositions can be advantageously formulated in the form of fluid compositions, suspensions, micro-suspensions, suspo-emulsions, wettable powders, granular concentrates, microemulsions and the like, all of which lend themselves to the application of treatment to the seeds and confer the necessary protection to the plants. The term "vehicle" indicates, in the present description, a natural or synthetic, organic or inorganic material with which the active substance is combined to facilitate its application to the plant, to the seeds or to the soil. Therefore, this vehicle is generally inert, and should be acceptable from the point of view of agriculture, especially for the plant being treated. The vehicle can be solid (clays, natural or synthetic silicates, silica, resins, waxes, solid fertilizers and the like) or liquid (water, alcohols, ketones, petroleum fractions, aromatic or paraffinic hydrocarbons, chlorinated hydrocarbons, liquefied gases and the like) ). Suitable liquid carriers are: aromatic hydrocarbons, especially C8 to C ?2 fractions, such as mixtures of substituted xylene or naphthalenes, italic esters such as dibutyl or dioctyl phthalate, aliphatic hydrocarbons such as cyclohexane or paraffins, alcohols or glycols, as well as their ethers or esters, such as for example ethylene glycol monomethyl ether, ketones such as cyclohexane, strongly polar solvents such as N-methyl-2-pyrrolidone, dimethisulfoxide or dimethylformamide and, if appropriate, epoxidized vegetable oils or soy oil; or water. The solid carriers that can be used, for example for sprinklers or dispersible powders, are calcite, talc, kaolin, montmorillonite or attapulgite, highly dispersible silica or absorbent polymers. The absorbent vehicles in potential particles for granules are pumice, crushed brick, sepiolite or bentonite, clay of the montmorillonite type and the possible nonabsorbent carrier materials are calcine or dolomite. Suitable surfactant compounds are nonionic, cationic and / or anionic surfactants with good emulsification, dispersion and wetting properties, depending on the nature of the active ingredients (A) and (Bl), (B2) and / or (B3) which they have to be formulated (either individually or in one of the various permutations or combinations). It should also be understood that the surfactants may be mixtures of surfactants. The surfactants commonly employed in formulation technology have been described, in the following publications, among others: "McCutcheon's Detergents and Emulsifiers Annual," MC Publishing Corp., Glen Rock, NJ, 1988. M. and J. Ash, "Encyclopedia of Surfactants", Vol. 1-111, Chemical Publishing Co., New York, 1980-1981. Suitable surfactants include, for example, salts of polyacrylic acid, salts of lignosulfonic acid, salts of phenolsulfonic acid or (mono- or dialkyl) naphthalenesulfonic acid, salts of lauryl sulfate, polycondensates of ethylene oxide with salts of lignosulfonic acid, polycondensates of ethylene oxide with fatty alcohols or with fatty acids or with fatty amines, substituted phenols (especially alkylphenols or arylphenols such as mono- and di- (polyoxyaliphenylp alkylphenol) phosphates, polyoxyalkylene alkylphenol carboxylates or polyoxyalkylene alkylphenol sulphates), salts of esters of sulfosuccinic acid, taurine derivatives (especially alkyl taurides), polycondensates of ethylene oxide with phosphated tristyrylphenols and polycondensates of ethylene oxide with phosphoric esters of alcohols or phenols. The presence of at least one surfactant is often required, since the active substance and / or the inert carrier are not soluble in water and the carrier agent for the application is water. In addition, adjuvants that improve the application are natural or synthetic phospholipids. from the series of cephalins and lecithins, for example phosphatidylethanolamine ,. phosphatidylserine, phosphatidylglycerin or lysolecithin. The agrochemical compositions generally contain: from 0.1 to 99%, especially from 10 to 75%, more specifically from 20 to 60% of the active substances (A) and (Bl), (B2) and / or (B3), the rest of the formulation consisting of a solid and / or liquid carrier (such as water, for example) together with the optional surfactant (s) and other optional inert ingredients known in the art such as, for example, protective colloids, adhesives, thickeners , thixotropic agents, penetrating agents, preservatives, stabilizers, antifoaming agents, antifreeze agents, sequestering agents, dyes, pigments, dyes and polymers. In one embodiment, commercial products are preferably formulated in the form of concentrates, while the end user usually uses diluted formulations.

In a specific embodiment, the formulation containing the macrolide compound, especially abamectin, is an aqueous suspension and comprises, as adjuvants of formulation, at least two surfactant compounds, in which (i) at least one surfactant has a molecular weight of less than 2200, preferably less than 1700, such as in the range of 400 to 1500, advantageously in the range of 600 to 1200, and a balance Hydrophilic-lipophilic (HLB) of at least 10, preferably in the range of 10 to 25, such as 12 to 20, preferably 14 to 18 and (ii) at least one The surfactant compound is nonionic and has a molecular weight of at least 2200, preferably at least 3000, for example in the range of 3500 to 15000, for example from 3500 to 10000, especially from 4000 to 7500, advantageously from 4500 to 6000, where from 10 to 85, for example from 15 to 80, preferably from 17 to 50% of the molecular weight of the compound contributes to the hydrophilic constituent of compound e, regardless of the proportion of hydrophilic substance, the molecular weight of the hydrophobic constituent of the compound is from 2000 to 10000, preferably from 2400 to 3900, more preferably from 3000 to 3800, such as from 3200 to 3700, provided that the weight ratio of surfactant to the macrolide compound is in the range of 0.08 to 0.5 , preferably from 0.1 to 0 .3, advantageously from 0.15 to 0.25 and the weight ratio of (ii): (i) is at least 0.5, for example at least 1.0, preferably at least 1.5, especially in the range from 2 to 5. , advantageously in the range of 2 to 3. Advantageously, three surfactant compounds are used, one of (i) and two of (ii) in the formulation. Examples of surfactant compounds (i) include an ionic, advantageously anionic surfactant such as one of the sulfate type (for example an aryl sulfate) and the phosphate type (such as an alkylphenol polyalkoxyether phosphate and an arylphenol polyalkoxyether phosphate) especially a surfactant of the phosphate type (such as a polyarylphenol polyalkoxyether phosphate). It is particularly advantageous if each surfactant compound (i) is of the same type, where a preferred type is a surfactant of the phosphate type. Specific examples of suitable anionic surfactants include: Sorprophor PS19 (Rhodia), Dowafax 30 COS (Dow), Soprophor 40384 (Rhodia) and Soprophor 3033 (Rhodia). Among the examples of the surfactant compound (ii) is a polyoxyalkylene oxide polymer such as a block polymer. Specific examples are polyoxyethylene polyoxypropylene block polymers and polyoxyethylene polyoxypropylene block polymer ethers and specific examples include Toximul 8320 (Stepan), Emulsogen 3510 (Clariant), Antarox PL / 122. { Rhodia), Pluronic L 101 (BASF), Pluronic L 122 (BASF) and Pluronic PE 10500 (BASF). In another embodiment, the formulation containing the macrolide compound, especially abamectin, is an aqueous suspension and comprises, as formulation adjuvants, at least two surfactant compounds, wherein (a) at least one is an anionic compound of the phosphate type and (b) at least one is an alkoxylated alcohol or nonionic phenol. In one embodiment, the molecular weight of the surfactant compounds (a) and (b), independently of one another, is less than 2200, preferably less than 1700, such as in the range of 400 to 1500, preferably in the range of 600 to 1200. The surfactant compound (a) preferably has a hydrophilic-lipophilic balance (HLB) of at least 10, preferably in the range of 10 to 25, such as 12 to 20, preferably 14 to 18 and (b) the surfactant compound preferably has a hydrophilic-lipophilic balance (HLB) of at least 5, preferably from 7 to 20, such as from 10 to 15. The weight ratio of the surfactant compounds (a) to (b) is generally in the range of from 1:10 to 10: 1, preferably from 5: 1 to 1: 1, especially from 3: 1 to 1: 1.

Examples of phosphate surfactants include alkylphenol polyalkoxyether phosphate, a block copolymer of polyalkoxyether phosphate, a polyarylphenol polyalkoxyether phosphate and an arylphenol polyalkoxyether phosphate. Examples of the alkoxylated alcohols include an alkoxylated alcohol (such as alkoxylated oil, alkoxylated alcohol with C5 to C18 carbon atoms in the alcohol). Examples of alkoxylated phenols include the polyalkoxyether of alkylphenol and the polyalkoxyether of (poly) arylphenol. Preferably, the compound (b) _- is an alkoxylated phenol. Specific examples of suitable anionic surfactants include: Soprophor 3D33 (Rhodia), Sorprophor PS19 (Rhodia) and Dowafax 30 C05 (Dow), and specific examples of nonionic surfactants include: Synperonic NP (üniqema), Soprophor BSÜ (Rhodia), Rhodasurf BC-610 (Rhodia), Toximul 8240 (Stepan) and Synperonic 91/4 (Uniqema). The anionic surfactants may be present in the form of acids or include alkali metals (such as lithium, sodium and potassium), alkaline earth metals (such as calcium and magnesium), ammonium and various amines (such as alkylanes, cycloalkylamines and alkanolamines). The Hydrophilic-Lipophilic Balance (HLB) value is an index of the hydrophilic nature of a compound proposed by Griffin. The HLB value of a polyoxyethylene alkyl ether can be determined, for example, by the Griffin equation. Value HLB = [(molecular weight of the hydrophilic portion) /. { molecular weight of the surfactant compound)] x 20 Groups, for example, sulfate or phosphate ions, may also contribute to the HLB value. The examples below are intended to illustrate and not to limit the invention.

EXAMPLES OF FORMULATION (% = percent by weight) EXAMPLE 1 An abamectin formulation is prepared by mixing the surfactant (s), the thickening agent, the polymer, the suspension aid, an antifoaming agent, a preservative and an antifreeze agent with water up to obtain a homogeneous phase. Next, abamectin is added and mixed. The obtained mixture is then subjected to wet milling by means of a ball mill (for example Dyno, Drais, Premier). The milling parameters are adjusted in such a way that the average particle size of the ground premix thus obtained is within the specifications (usually an average particle size of 2.0um maximum). Finally, add the buffer (if included) and a smaller amount of water and mix the final product for at least 30 minutes.

Example 1: FS% p / p Abamectin 46.3 Styrylphenol Polyethoxyster Phosphate 1.5 Propylene glycol 5.0 Triestirephenol with 16 moles of EO 1.0 Silicone defoaming agent 0.2 Conservative 0.06 Linear polysaccharide 0.2 Water (rest) EXAMPLE 2 This formulation is suitable for mixtures of solid and liquid active ingredients. The active ingredient (or the active ingredients) is solidly mixed with a portion of the emulsifiers and water and the mixture is thoroughly milled in a suitable mill. Another portion of the emulsifiers and water is mixed with the active ingredient (s). The two mixtures are combined together with any other inert ingredients (such as pigments, thickeners, etc.) that are used in the formulation.

Example 2: FS% p / p Active ingredients 12.5 (azoxystrobin: fludioxonil: R-metalaxyl) (15: 2.5: 7.5) Propylene glycol 7.0 Titanium dioxide 10.0 Styrophenyl Phosphate Polyethoxide 2.0 Triestirephenol with 16 moles of EO 2.0 Butanol copolymer PO / EO 2.0 Sodium hydroxide (30%) "0.3 Silicone defoaming agent 0.2 Aqueous dispersion based on vinyl acetate and 10.0 ethylene Heteropolisaccharide 0.35 Conservative 0.15 Water rest Example 3 -Preparation of the Seed Treatment Formulation as a Mixture of Tank The seed treatment compositions of Examples 1 and 2 are combined in a suspension with the following commercially available seed treatment products: Cruiser® 5 FS (thiamethoxam) and Systhane® 40 WP. { miclobutanil) in an amount sufficient to obtain a concentration of the active ingredients of 100 g of i. to. / 100 kg of seeds (Example 1): 25 g of a.i./lOO kg of seeds (Example 2): 21 g of i.a./lOO kg of seeds (myclobutanil) and 30 g of i.a./lOO.OOO seeds (thiamethoxam). The final combined composition is suitable for use in application to seeds by spraywetting or mixing in a container with a volume of 200 ml to 3 liters of the final combined composition - for every 100 kg of seed. The active ingredient is distributed uniformly on the surface of the seed by rotating and / or by shaking the container. No phytotoxicity is observed with the cottonseeds that were coated with the formulation of Example 3. Adequate control of insect pests and nematodes is obtained.

Example 4 - BIOLOGICAL EXAMPLES Introduction: This example compares the efficacy of thiamethoxam (CAS # 153719-23-4), abamectin (CAS # 65195-56-4 and No, 65195-55-3) and the combination of both compounds used as treatment of seeds to fight insects (Thysanoptera) on cotton.

Control - Only treatment of the seeds with the fungicide base ("sin'insecticida or nematicida) (a) A formulation for the treatment of seeds with fungicide base is prepared by diluting a concentrate with a content of 3.32% mefenoxam (CAS # 31860 -33-8) in water as a vehicle This dilution of the formulation is applied for one to two minutes at ambient temperature at a rate of approximately one kilogram of Delta and Pine Land cotton seeds (DP 555 BR) in a seed treater Hege (Hege) in a proportion of 0.30 mg of active ingredient for each individual seed The treated seeds are allowed to air dry and are sent and stored at room temperature before planting (approximately two weeks).

Seeds treated with thiamethoxam (b) A seed treatment formulation is prepared by diluting the Cruiser® 5FS seed insecticide (Syngenta Crop Protection, Inc.), which contains 49% thiamethoxam and the base fungicide concentrate in (a); in water as a vehicle. This dilution of the formulation is applied for one to two minutes at room temperature to about one kilogram Delta and Pine Land (DP 555 SR) in a Hege seed treater (Hege) at a ratio of 0.34 mg of active ingredient per individual seed. The treated seeds are allowed to air dry and ship and stored at room temperature before planting (approximately two weeks).

Seeds treated with Abamectin (c) A formulation for seed treatment is prepared by diluting a nematicide abamectin formulation for the treatment of seeds with a content of 46.3% abamectin and the base fungicide concentrate (a); in water as a vehicle. This formulation dilution is applied for one to two minutes at room temperature to about one kilogram Delta and Pine Land (DP 555 SR) in a Hege seed treater at a ratio of 0.15 mg of active ingredient per individual seed. The treated seeds are allowed to air dry and are sent and stored at room temperature before planting (approximately two weeks).

Combinatorial treatment The exposed formulations of thiamethoxam and abamectin were combined together with water as carrier and with the base fungicide (a). Thiamethoxam and abamectin are applied in proportions of 0.34 and 0.15 mg of active ingredient per seed, respectively. This formulation dilution is applied for one to two minutes at room temperature to about one kilogram Delta and Pine Land (DP 555 SR) in a Hege seed treater. I know that the treated seeds are air dried and sent and stored at room temperature before planting (approximately two weeks). Control (a) and treated seeds (b), (c) and (d) were planted in lots of land in two separate tests (1) and (2) as follows: Cotton seeds are sown (4 seeds per foot (30.48 cm)) in batches with 2-row dimensions (spacing of 36 inches (91.44 cm) between the rows) by 30 feet (9 m) in a randomized block layout consisting of a control control (a) , abamectin plus a base fungicide (c), thiomethoxam plus a base fungicide (b) and the combination of thiomethoxam and abamectin plus a base fungicide (d). The following data are collected from these tests: 1) number of adult Thysanoptera per five plants, 2) the number of immature Thysanoptera per five plants and the damage caused to the plants. Thysanoptera from five plants were collected at random within each repetition of each treatment by collecting the Thysanoptera in alcohol and counting the numbers of Thysanoptera using a dissecting lens in the laboratory. Damage rates were calculated within each repetition per treatment using a visual rating scale that assigns ratings to the damage caused to the plants (stagnation, rolling of the leaves, etc.) on a scale of 1 to 5 (1 = no damage, 3 = moderate damage and 5 = serious damage).

Table 1 - Thysanoptera control in cotton on a research farm - Test (1) Thysanoptera immature Thysanoptera Damage adults 14 DAP 21 DAP 14 DAP 21 DAP Control (a) 81.5 90.75 23.5 4.5 Thiamethoxam 13 20.25 5 3.3 (b) Abamectin 39.25 50.5 13 4 (c) Thiamethoxam + 3.5 11.5 6.25 3.12 Abamectin (d) Table 2. Thysanoptera control in cotton on a research farm - Test (2) Immature Thysanoptera 14 DAP Control (a) 137.5 Thiamethoxam (b) 15 Abamectin (c) 71.5 Thiamethoxam + Abamectin (d) 3.75 The results of these tests indicate that the effectiveness of the combinatorial treatment of the seeds (d), which includes thiamethoxam and abamectin, is better than the individual treatments with thiamethoxam (b) and abamectin (c). These findings have been well documented in multiple tests to detect both mature and adult Thysanoptera in cotton (Table 1 and Table 2). In tests 1 and 2, control without treatment had the highest number of thrips, followed by treatment with abamectin only. The treatment with abamectin only offered some activity on the Thysanoptera (-50% control, compared to the untreated control.) These results were surprising, since the abamectin is not systemic Cottonseeds treated with thiamethoxam (b) exhibited a control of approximately 85% of the Thysanoptera at 14 and 21 days after planting, while the combination of thiamethoxam and abamectin (d) gave control of more than 95% of the Thysanoptera. that the present invention has at least a binary pesticidal composition for the protection of plant propagation materials, variations in proportions, procedures and materials can be made without departing from the scope of the present invention, defined by the following claims. notes that in relation to this date, the best method known to the applicant to implement the c This invention is that which is clear from the present description of the invention.

Claims (18)

1. CLAIMS Having described the invention as above, the content of the following claims is claimed as property: 1. A pesticidal composition at least binary, characterized in that it comprises, as active ingredients: (A) an effective amount as a nematicide of at least one macrolide compound selected from abamectin, emamectin benzoate and spinosad; and (B) an insecticidally effective amount of at least one insecticide selected from imidacloprid, clothianidin and thiamethoxam.
2. 2. A composition according to claim 1, characterized in that it contains (A) an effective amount as an abamectin nematicide.
3. 3. A composition according to claim 1 or claim 2, characterized in that it contains (Bl) an insecticidally effective amount of imidacloprid.
4. 4. A composition according to claim 1 or claim 2, characterized in that it contains (B2) an effective insecticidal amount of clothianidin.
5. 5. A composition according to claim 1 or claim 2, characterized in that it contains (B3) an insecticidally effective amount of thiamethoxam.
6. 6. A composition according to claim 1, characterized in that it contains: - (A) an effective amount as nematicide of abamectin (B3) an insecticidally effective amount of thiamethoxam.
7. 7. A composition according to any of claims 1 to 6, characterized in that the ratio of the active ingredients (A): (B) is (100 g - 400 g): (300 g - 500 g) per 100 kg / of seed.
8. 8. A composition according to any of claims 1 to 7, characterized in that it further comprises an effective amount as a fungicide of (C) a compound selected from azoxystrobin, fludioxonil, R-metalaxyl and myclobutanil.
9. 9. Plant propagation material resistant to pests, characterized in that it comprises plant propagation material treated with a pesticidally effective amount of a pesticidal composition according to any of claims 1 to 8.
10. 10. A plant propagation material pest resistant according to claim 9, characterized in that the pesticidal composition contains (A) an effective amount as an abamectin nematicide.
11. 11. A plant propagation material resistant to pests according to claim 9 or claim 10, characterized in that the pesticidal composition contains (Bl) an insecticidally effective amount of imidacloprid.
12. 12. A plant propagation material resistant to pests according to claim 9 or claim 10, characterized in that the pesticidal composition contains (B2) an insecticidally effective amount of clothianidin.
13. 13. A pest-resistant plant propagation material according to claim 9 or claim 10, characterized in that the pesticidal composition contains (B3) an insecticidally effective amount of thiamethoxam.
14. 14. A plant propagation material resistant to pests according to claim 9, characterized in that the pesticidal composition comprises (A) an effective amount as nematicide of abamectin and (B3) an insecticidally effective amount of thiamethoxam.
15. 15. A plant propagation material resistant to pests according to any of claims 9 to 14, characterized in that the ratio of the active ingredients (A): (B) is (100 g - 400 g): (300 g -500 g) per 100 kg / of seed.
16. 16. A method for the protection of propagation material of plants against attack by nematodes and insects, characterized in that it comprises the treatment of plant propagation material with an effective amount as nematicide and insecticide of a composition according to any of the claims 1 to 8.
17. 17. A method according to claim 16, characterized in that the composition further comprises an effective fungicidal amount of (C) a compound selected from azoxystrobin, fludioxonil, R-metalaxyl and myclobutanil.
18. 18. A method according to claim 16 or claim 17, characterized in that the plant propagation material is a plant seed selected from cotton, tomatoes, peppers, melons, cantaloupe, courgettes and cucumbers.