MXPA03005676A - Formas de dosis solidas de sodio de divalproex. - Google Patents
Formas de dosis solidas de sodio de divalproex.Info
- Publication number
- MXPA03005676A MXPA03005676A MXPA03005676A MXPA03005676A MXPA03005676A MX PA03005676 A MXPA03005676 A MX PA03005676A MX PA03005676 A MXPA03005676 A MX PA03005676A MX PA03005676 A MXPA03005676 A MX PA03005676A MX PA03005676 A MXPA03005676 A MX PA03005676A
- Authority
- MX
- Mexico
- Prior art keywords
- dosage forms
- solid dosage
- divalproex sodium
- directed
- divalproex
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invencion se dirige a un proceso acuoso para granular compuestos de valproato, en el cual el pH de la solucion de granulacion se mantiene a un pH de 5 o abajo. La invencion tambien se dirige a formas de dosis en las cuales el contenido residual de solventes organicos se reduce a un nivel de 0.2% p/p o menos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/748,659 US20020127277A1 (en) | 2000-12-22 | 2000-12-22 | Solid dosage forms of divalproex sodium |
PCT/US2001/043158 WO2002051400A2 (en) | 2000-12-22 | 2001-11-27 | Solid dosage forms of divalproex sodium |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03005676A true MXPA03005676A (es) | 2004-04-21 |
Family
ID=25010383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03005676A MXPA03005676A (es) | 2000-12-22 | 2001-11-27 | Formas de dosis solidas de sodio de divalproex. |
Country Status (5)
Country | Link |
---|---|
US (1) | US20020127277A1 (es) |
BR (1) | BR0112281A (es) |
CA (1) | CA2431375A1 (es) |
MX (1) | MXPA03005676A (es) |
WO (1) | WO2002051400A2 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040005357A1 (en) * | 2002-07-03 | 2004-01-08 | Sherman Bernard Charles | Extended-release tablets comprising divalproex sodium |
US20040176463A1 (en) * | 2003-02-05 | 2004-09-09 | Daniella Licht | Immediate release formulation of n-(2-propylpentanoyl)glycinamide |
US20070048379A1 (en) * | 2005-08-29 | 2007-03-01 | Mintong Guo | Valproate tablet |
CN101686931B (zh) * | 2007-06-06 | 2013-06-19 | 巴斯夫欧洲公司 | 用于制备可咀嚼片剂和锭剂的药物配制剂 |
AU2008258627A1 (en) * | 2007-06-06 | 2008-12-11 | Basf Se | Pharmaceutical formulation for the production of rapidly disintegrating tablets |
CN101393181B (zh) * | 2008-10-20 | 2012-04-25 | 陕西天森药物研究开发有限公司 | 双丙戊酸钠中有关物质的测定方法 |
CN111349003B (zh) * | 2018-12-20 | 2023-10-03 | 四川科瑞德制药股份有限公司 | 一种丙戊酸钠的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ270438A (en) * | 1995-02-02 | 1996-03-26 | Bernard Charles Sherman | Solid (granular) mixture of valproic acid (di-n-propyl acetic acid) and its sodium salt; pharmaceutical compositions |
DK0921793T3 (da) * | 1997-03-11 | 2000-12-18 | Hexal Ag | Faste, ikke-henflydende formuleringer af natriumvalproat |
AT408718B (de) * | 1999-12-02 | 2002-02-25 | Gerot Pharmazeutika | Natriumvalproat-granulat mit verringerter hygroskopizität |
-
2000
- 2000-12-22 US US09/748,659 patent/US20020127277A1/en not_active Abandoned
-
2001
- 2001-11-27 BR BR0112281-9A patent/BR0112281A/pt not_active Application Discontinuation
- 2001-11-27 CA CA002431375A patent/CA2431375A1/en not_active Abandoned
- 2001-11-27 WO PCT/US2001/043158 patent/WO2002051400A2/en not_active Application Discontinuation
- 2001-11-27 MX MXPA03005676A patent/MXPA03005676A/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2002051400A3 (en) | 2002-12-27 |
US20020127277A1 (en) | 2002-09-12 |
WO2002051400A2 (en) | 2002-07-04 |
BR0112281A (pt) | 2004-10-19 |
CA2431375A1 (en) | 2002-07-04 |
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