MXPA02012352A - Vaccine for congenital tremors in pigs. - Google Patents

Vaccine for congenital tremors in pigs.

Info

Publication number
MXPA02012352A
MXPA02012352A MXPA02012352A MXPA02012352A MXPA02012352A MX PA02012352 A MXPA02012352 A MX PA02012352A MX PA02012352 A MXPA02012352 A MX PA02012352A MX PA02012352 A MXPA02012352 A MX PA02012352A MX PA02012352 A MXPA02012352 A MX PA02012352A
Authority
MX
Mexico
Prior art keywords
pcv
pig
congenital tremors
pigs
polypeptide
Prior art date
Application number
MXPA02012352A
Other languages
Spanish (es)
Inventor
Charles L Kanitz
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of MXPA02012352A publication Critical patent/MXPA02012352A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

The invention is based on the cloning of porcine circovirus (PCV) strains from pigs with congenital tremors. These results provide a first step for the development of diagnostic and therapeutic applications for congenital tremors in a pig. The diagnostic method comprises determining whether the pig has been infected by a porcine circovirus strain of type 1 or type 2. The invention further provides a method for the prevention or treatment of congenital tremors in a pig, which method comprises administering to the pig an effective amount of an immunogenic PCV 1 or PCV 2 polypeptide or of a nucleic acid encoding this polypeptide. Another subject of the invention is the new PCV nucleic acid sequences identified by the inventors and the polypeptides encoded by these sequences, as well as the new PCV isolates and immunogenic preparations thereof.
MXPA02012352A 2000-06-15 2001-06-15 Vaccine for congenital tremors in pigs. MXPA02012352A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21171000P 2000-06-15 2000-06-15
PCT/US2001/019220 WO2001096377A2 (en) 2000-06-15 2001-06-15 Vaccine for congenital tremors in pigs

Publications (1)

Publication Number Publication Date
MXPA02012352A true MXPA02012352A (en) 2004-09-06

Family

ID=22788038

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012352A MXPA02012352A (en) 2000-06-15 2001-06-15 Vaccine for congenital tremors in pigs.

Country Status (6)

Country Link
EP (1) EP1290016A2 (en)
JP (1) JP2004503234A (en)
AU (1) AU2001266940A1 (en)
CA (1) CA2410229A1 (en)
MX (1) MXPA02012352A (en)
WO (1) WO2001096377A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040062775A1 (en) 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
FR2772047B1 (en) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E GENOMIC SEQUENCE AND POLYPEPTIDES OF CIRCOVIRUS ASSOCIATED WITH PIGLET LOSS DISEASE (MAP), APPLICATIONS TO DIAGNOSIS AND TO PREVENTION AND / OR TREATMENT OF INFECTION
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7279166B2 (en) 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
GB0318096D0 (en) * 2003-08-01 2003-09-03 Queen Mary & Westfield College Vaccine
UA95602C2 (en) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Pcv2 immunogenic compositions and methods of producing such compositions
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
CN103285387B (en) * 2004-12-30 2017-07-25 勃林格殷格翰动物保健有限公司 PCV2 immunogenic compositions and the method for producing this composition
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
ES2589928T3 (en) * 2005-04-13 2016-11-17 Merial, Inc. Procedure for the production of porcine circovirus
TW200643171A (en) * 2005-06-07 2006-12-16 Temasek Life Sciences Lab Ltd Porcine circovirus type 2 vaccines
DK2371385T3 (en) 2005-12-29 2015-11-30 Boehringer Ingelheim Vetmed Use of a PV2 immunogen composition for reduction of clinical symptoms in pigs
EP3320919B1 (en) 2005-12-29 2020-05-27 Boehringer Ingelheim Animal Health USA Inc. Multivalent pcv2 immunogenic compositions and methods of producing such compositions
EP2859900A1 (en) 2006-12-11 2015-04-15 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
AU2007333857B2 (en) * 2006-12-15 2014-05-15 Boehringer Ingelheim Animal Health USA Inc. Treatment of pigs with PCV2 antigen
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
CA2712006A1 (en) 2008-01-23 2009-10-15 Boehringer Ingelheim Vetmedica, Inc. Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
WO2009093251A2 (en) * 2008-01-24 2009-07-30 Gavish-Galilee Bio Applications Ltd Reovirus vaccine based on sigma c protein sequence
TWI627281B (en) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 Methods of reducing viricidal activity in pcv-2 compositions and pcv-2 compositions with an improved immunogenicity
HUP1100470A2 (en) * 2011-08-30 2013-03-28 Mezoegazdasagi Biotechnologiai Kutatokoezpont Nanoparticle-based veterinary vaccine
KR20160046879A (en) 2013-09-25 2016-04-29 조에티스 서비시즈 엘엘씨 Pcv2b divergent vaccine composition and methods of use
WO2015051099A1 (en) 2013-10-02 2015-04-09 Boehringer Ingelheim Vetmedica, Inc. Pcv2 orf2 protein variant and virus like particles composed thereof
CN104109704B (en) * 2014-07-09 2016-05-04 福州大学 A kind of isolation and purification method of Recombinant Swine PCV-II capsid protein inclusion body
US9920302B2 (en) * 2015-08-31 2018-03-20 Boehringer Ingelheim Vetmedica Gmbh Pestivirus vaccines for congenital tremors
CN111087452A (en) * 2019-12-18 2020-05-01 中国农业科学院兰州兽医研究所 Prokaryotic soluble expression method of porcine circovirus 2b subtype Cap protein
CN111154915A (en) * 2020-01-06 2020-05-15 咸阳职业技术学院 PCR differential diagnosis kit for porcine circovirus type 4 and type 3 and detection method thereof
CN112014561B (en) * 2020-09-03 2022-04-19 扬州大学 Application of porcine circovirus type 4 specific antigen in preparation of kit for detecting porcine circovirus type 4 antibody and kit

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA78180C2 (en) * 1997-10-03 2007-03-15 Меріаль Porcine circovirus, vaccines and diagnostic reagents
PT2363488E (en) * 1997-12-11 2015-01-13 Univ Belfast Postweaning multisystemic wasting syndrome virus from pigs

Also Published As

Publication number Publication date
JP2004503234A (en) 2004-02-05
AU2001266940A1 (en) 2001-12-24
EP1290016A2 (en) 2003-03-12
CA2410229A1 (en) 2001-12-20
WO2001096377A2 (en) 2001-12-20
WO2001096377A3 (en) 2002-06-13

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