MXPA01009369A - Novel methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators. - Google Patents
Novel methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators.Info
- Publication number
- MXPA01009369A MXPA01009369A MXPA01009369A MXPA01009369A MXPA01009369A MX PA01009369 A MXPA01009369 A MX PA01009369A MX PA01009369 A MXPA01009369 A MX PA01009369A MX PA01009369 A MXPA01009369 A MX PA01009369A MX PA01009369 A MXPA01009369 A MX PA01009369A
- Authority
- MX
- Mexico
- Prior art keywords
- colorectal cancer
- methods
- screening
- compositions
- modulators
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 206010009944 Colon cancer Diseases 0.000 title abstract 4
- 208000001333 Colorectal Neoplasms Diseases 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Described herein are methods that can be used for diagnosis and prognosis of colorectal cancer. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate colorectal cancer. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in colorectal and other cancers are described.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/268,866 US6316272B1 (en) | 1999-03-15 | 1999-03-15 | Methods of diagnosis of colorectal cancer and methods of screening for colorectal cancer modulators |
US09/436,983 US6294343B1 (en) | 1999-11-09 | 1999-11-09 | Methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators |
US09/435,945 US6773878B1 (en) | 1999-11-09 | 1999-11-09 | Methods of diagnosing of colorectal cancer, compositions, and methods of screening for colorectal cancer modulators |
US45085799A | 1999-11-29 | 1999-11-29 | |
US45385099A | 1999-12-02 | 1999-12-02 | |
US49344400A | 2000-01-28 | 2000-01-28 | |
PCT/US2000/007044 WO2000055633A2 (en) | 1999-03-15 | 2000-03-15 | Methods of screening for colorectal cancer modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA01009369A true MXPA01009369A (en) | 2003-06-06 |
Family
ID=27559474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA01009369A MXPA01009369A (en) | 1999-03-15 | 2000-03-15 | Novel methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1163524A2 (en) |
JP (1) | JP2004510951A (en) |
AU (1) | AU3755300A (en) |
CA (1) | CA2369319A1 (en) |
MX (1) | MXPA01009369A (en) |
WO (1) | WO2000055633A2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981220A (en) | 1996-03-27 | 1999-11-09 | Human Genome Sciences, Inc. | Epidermal differentiation factor |
JP2001509028A (en) | 1997-01-16 | 2001-07-10 | ヒューマン ジノーム サイエンシーズ,インコーポレイテッド | Human extracellular matrix-1 |
CA2341142A1 (en) | 1998-09-02 | 2000-03-09 | Diadexus Llc | A novel method of diagnosing, monitoring, staging, imaging and treating various cancers |
CA2401887A1 (en) * | 2000-03-16 | 2001-09-27 | K.U. Leuven Research & Development | Nusap, a novel gene encoding a tissue-specific nuclear protein, useful as a diagnostic tool and therapeutic agent |
US20030077568A1 (en) * | 2000-09-15 | 2003-04-24 | Gish Kurt C. | Methods of diagnosis of colorectal cancer, compositions and methods of screening for colorectal cancer modulators |
US20050272120A1 (en) | 2001-06-20 | 2005-12-08 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
EP2000545B1 (en) | 2001-06-20 | 2011-08-31 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of lung tumor |
WO2003021229A2 (en) * | 2001-09-05 | 2003-03-13 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
US7622260B2 (en) | 2001-09-05 | 2009-11-24 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
US7429450B2 (en) * | 2001-11-15 | 2008-09-30 | The Regents Of The University Of Michigan | HIP1 cancer markers |
US7473526B2 (en) | 2002-03-29 | 2009-01-06 | Veridex, Llc | Breast cancer prognostic portfolio |
US7348142B2 (en) | 2002-03-29 | 2008-03-25 | Veridex, Lcc | Cancer diagnostic panel |
JP2005522228A (en) * | 2002-04-11 | 2005-07-28 | オックスフォード グライコサイエンシス (ユーケイ) リミテッド | Proteins involved in cancer |
US7252976B2 (en) * | 2002-08-28 | 2007-08-07 | Board Of Regents The University Of Texas System | Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample |
US20040146921A1 (en) * | 2003-01-24 | 2004-07-29 | Bayer Pharmaceuticals Corporation | Expression profiles for colon cancer and methods of use |
EP1613966A2 (en) | 2003-04-08 | 2006-01-11 | Colotech A/S | A method for detection of colorectal cancer in human samples |
EP1652923B1 (en) | 2003-08-08 | 2011-10-12 | Perseus Proteomics Inc. | Gene overexpressed in cancer |
NZ544432A (en) * | 2005-12-23 | 2009-07-31 | Pacific Edge Biotechnology Ltd | Prognosis prediction for colorectal cancer using a prognositc signature comprising markers ME2 and FAS |
WO2008021115A2 (en) | 2006-08-14 | 2008-02-21 | The Brigham And Women's Hospital, Inc. | Diagnostic tests using gene expression ratios |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2104964A1 (en) * | 1991-02-28 | 1992-08-29 | Ruth Sager | Cancer diagnosis and therapy with tumor suppressor genes |
US6455678B1 (en) * | 1996-04-26 | 2002-09-24 | Amcell Corporation | Human hematopoietic stem and progenitor cell antigen |
WO1997042209A1 (en) * | 1996-05-03 | 1997-11-13 | Human Genome Sciences, Inc. | Human rad |
US5874235A (en) * | 1997-07-18 | 1999-02-23 | The Johns Hopkins University | Screening assays for cancer chemopreventative agents |
-
2000
- 2000-03-15 EP EP00916451A patent/EP1163524A2/en not_active Withdrawn
- 2000-03-15 MX MXPA01009369A patent/MXPA01009369A/en unknown
- 2000-03-15 WO PCT/US2000/007044 patent/WO2000055633A2/en not_active Application Discontinuation
- 2000-03-15 JP JP2000605214A patent/JP2004510951A/en active Pending
- 2000-03-15 AU AU37553/00A patent/AU3755300A/en not_active Abandoned
- 2000-03-15 CA CA002369319A patent/CA2369319A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2000055633A9 (en) | 2001-11-22 |
EP1163524A2 (en) | 2001-12-19 |
CA2369319A1 (en) | 2000-09-21 |
AU3755300A (en) | 2000-10-04 |
WO2000055633A3 (en) | 2001-02-22 |
WO2000055633A2 (en) | 2000-09-21 |
JP2004510951A (en) | 2004-04-08 |
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