MXPA01005015A - Low-irritation antiperspirant and deodorant compositions - Google Patents

Abstract

Disclosed are topical compositions which comprise from about 0.01%to about 60%by weight of an antiperspirant and/or deodorant active;from about 1%to about 60%by weight of a volatile, nonpolar hydrocarbon liquid having a solubility parameter of less than about 7.5 (cal/cm3)0.5 and a vapor pressure as measured at 25°C of from about 0.01 mmHg to about 6.0 mmHg;and from about 1%to about 60%by weight of a skin irritation-mitigating material having a vapor pressure equal to or less than that of the volatile, nonpolar hydrocarbon liquid, preferably a silicone-containing liquid;wherein the weight ratio of the volatile, nonpolar hydrocarbon liquid to the mitigating material is from about 5:1 to about 1:50. It has been found that the volatile, nonpolar hydrocarbon liquid as defined herein can cause skin irritation when used in an antiperspirant or deodorant composition, when used at relatively low concentrations, but that the skin irritation can be reduced or eliminated by the addition of a skin irritation-mitigating material, provided the material has the requisite vapor pressure and weight ratio relative to the volatile, nonpolar hydrocarbon liquid.

Description

ANTITRANSPIRANT AND DEODORANT COMPOSITIONS WITH LOW IRRITATION TECHNICAL FIELD The present invention relates to antiperspirant and deodorant compositions with low irritation comprising a non-polar, volatile hydrocarbon liquid, and a material for mitigating skin irritation. The mitigating material reduces or eliminates skin irritation associated with the topical application of the volatile, nonpolar hydrocarbon liquid from an antiperspirant or deodorant composition.

BACKGROUND OF THE INVENTION There are many types of topical antiperspirant and deodorant products that are commercially available or otherwise known in the art of antiperspirants and deodorants. Most of these products are formulated as spray or pump sprays, roll-on liquids, creams, emulsions, gels, gel solids or other solid or semi-solid stick formulations and comprise a deodorant (eg, triclosan) and / or astringent material (eg, zirconium and / or aluminum salts) incorporated in a suitable carrier. These products are designed to provide effective perspiration and / or odor control while also being cosmetically acceptable during and after application on the axillary area or other areas of the skin. Within this group of products, antiperspirant and deodorant products containing volatile silicone fluids have become especially popular among consumers. These products can be aqueous or anhydrous and can contain up to 80% by weight of a volatile silicone fluid such as cyclopentasiloxane. The volatile silicone gives the composition a dry skin sensation during application and due to its volatility evaporates quickly after application leaving the surface applied with a smooth and dry feeling without white residual marks. However, volatile silicones are expensive and substantially increase the cost of antiperspirant and deodorant products. To control the relatively high formulation cost associated with the use of volatile silicone fluids, non-polar, volatile hydrocarbon liquids have been used in place of some or all of the volatile silicones. Volatile, non-polar hydrocarbon liquids are usually less expensive than volatile silicones and, like volatile silicones, also help to provide the composition with a dry feeling during and after application to the skin. Examples of compositions containing nonpolar, volatile hydrocarbon liquid are described in U.S. Patent 4,724,139, issued February 9, 1988 to Palinczar and U.S. Patent 4,265,878, issued May 5, 1981 to Keil. However, it has been found that antiperspirant and deodorant compositions containing non-polar, volatile hydrocarbon liquid can be very irritating to the skin even when used at relatively low concentrations. It is believed that this irritation problem has not been previously discussed in the literature as it is associated with the use of these materials in deodorant and antiperspirant products. For example, U.S. Patent 4,724,139 (Palinczar) teaches that volatile silicones can be replaced with volatile nonpolar hydrocarbon liquid in antiperspirant sticks since the two materials have similar characteristics, including good characteristics Cosmetic, high volatility and low skin irritation. However, it has now been found that these nonpolar, volatile hydrocarbon liquids, when placed in either an antiperspirant or deodorant composition can cause significant irritation of the skin at the time and after topical application even when the Concentration of these liquids is relatively low in the finished product. It is now also found that antiperspirant and deodorant compositions containing a non-polar hydrocarbon liquid, volatile, can be formulated in order to minimize or eliminate the skin irritation caused by the volatile, non-polar hydrocarbon liquid. It has been found that this skin irritation can be minimized or eliminated by the concurrent use of selected solvents that act as materials to mitigate skin irritation. (mitigating materials), with the proviso that the weight ratio of the non-polar, volatile hydrocarbon liquid to the mitigating material is between about 5: 1 and 1:50. Select solvents should have a vapor pressure equal to or less than that of the volatile, nonpolar hydrocarbon liquid. Non-volatile silicone fluids are the skin irritation mitigation materials that are very importantly preferred. Therefore, it is an object of the present invention to provide an antiperspirant or deodorant composition containing a non-polar, volatile hydrocarbon liquid and causing little or no skin irritation when applied topically to the armpit or other area of the skin. skin. A further objective of the present invention is to provide this composition as well. contain a material to mitigate skin irritation, preferably a non-volatile silicone fluid, to help minimize or eliminate the development of skin irritation after topical application.

BRIEF DESCRIPTION OF THE INVENTION The present invention is directed to antiperspirant and deodorant compositions comprising between about 0.01% and 60% by weight of an antiperspirant and / or deodorant active agent; between about 1% and 60% by weight of a volatile, nonpolar hydrocarbon liquid having a solubility parameter less than about 7.5 (cal / cm 3) 0-5 and a vapor pressure as measured at 25 ° C between approximately O.OlmmHg and 6.0 mmHg; and between about 1% and 60% by weight of a mitigating material having a vapor pressure equal to or less than the vapor pressure of the volatile, non-polar hydrocarbon liquid, selected for use in the composition, wherein the ratio in Weight of the volatile, non-polar hydrocarbon liquid to the mitigating material is between about 5: 1 and 1:50. It has been found that volatile, nonpolar hydrocarbon liquid, as defined herein, can cause skin irritation when applied topically from an antiperspirant or deodorant composition, although that skin irritation can be reduced or eliminated. by adding selected amounts of mitigating materials as defined herein. The mitigating materials are preferably a non-polar, non-volatile hydrocarbon emollient, and / or a non-volatile silicone material, preferably a non-volatile silicone fluid, provided that they are formulated in the proportions by weight and pressures of selected steam as described herein.

DETAILED DESCRIPTION OF THE INVENTION The antiperspirant and deodorant compositions of the present invention comprise as essential elements 1) an antiperspirant and / or deodorant active agent, 2) a volatile, non-polar hydrocarbon liquid, as defined herein, and 3) a material for mitigating skin irritation in a proportion by weight and vapor pressure defined in relation to the volatile, non-polar hydrocarbon liquid. The term "volatile" as used herein, unless otherwise specified, refers to those materials that are liquid under ambient conditions and have a vapor pressure as measured at 25 ° C of at least 0.01 mmHg, typically between approximately O.OlmmHg and 6.0 mmHg. In contrast, the term "non-volatile" as used herein, unless otherwise specified, refers to those materials that are not volatile as the term is defined herein. These "non-volatile" materials will typically be in the form of a liquid, semi-solid or solid and have no vapor pressure as measured at 25 ° C. The term "anhydrous" as used herein, refers to the preferred embodiments of the compositions of the present invention, and means that these preferred embodiments are substantially free of aggregates or free of water. From the formulation point of view, this means that preferred embodiments contain less than about 5%, preferably less than about 3%, more preferably less than about 1%, most preferably zero percent by weight of free or added water, other than water of hydration typically associated with the active particulate antiperspirant. The term "ambient conditions" as used herein, refers to surrounding conditions at about one atmosphere of pressure (1 atm), at about 50% relative humidity, and about 25 ° C, unless otherwise specified. way. All values, amounts and measurements described herein are obtained under ambient conditions unless otherwise specified.

The term "non-polar", in the sense in which it is used herein, refers to those materials having a solubility parameter of less than about 7.5 (cal / cm3) ° ', typically between about 5.0 and 7.5 (cal / cm 3), 0.5 These materials will normally be materials that contain silicone or organic materials that contain few, if any, functional groups. The antiperspirant and deodorant compositions of the present invention, including the corresponding methods of the present invention, may comprise, consist of, or consist essentially of essential elements and limitations of the invention described herein, as well as any of the ingredients - Additional or optional, components or limitations described herein. Unless otherwise specified, all percentages, parts and proportions are presented by weight of the total composition. All weights belong to the listed ingredients, are based on the specific ingredient level and, therefore, do not include solvents, carriers, by-products, fillers or other minor ingredients that may be included in commercially available materials, unless Specify otherwise. The essential elements of the antiperspirant and deodorant composition of the present invention which include the essential elements of the application of the corresponding methods are described in greater detail hereinafter.

I. Antiperspirant Active The compositions of the present invention include those embodiments which are intended to be used as antiperspirant compositions and which comprise an antritranspirant active agent suitable for application to human skin. The active agent can be dissolved in the selected solvent, or it can be dispersed throughout the composition as unsolubilized or partially solubilized solids. The concentration of the antiperspirant active in the composition should be sufficient to provide the desired moisture control and / or perspiration odor from the selected antiperspirant formulation. The antiperspirant embodiments of the present invention preferably comprise the antiperspirant active agent at concentrations between about 0.01% and 60%, more preferably between about 5% and 35%, even more preferably between about 7% and 26% in weight of the composition. These percentages by weight are calculated on an anhydrous metal salt base exclusive of water and any complexing agents such as glycine, glycine salts or other complexing agents. As formulated in the composition, the antiperspirant actives are preferably in the form of dispersed solids having a preferred average particle size or diameter less than 100 μm, preferably less than 50 μm. Also preferred are dispersed solid particulates having an average particle size or diameter of less than 1 μm, even more preferably less than 0.4 μm and most preferably less than 0.2 μm. The antiperspirant active agent may be solubilized or partially solubilized in the aqueous or anhydrous antiperspirant compositions of the present invention. Anhydrous antiperspirant compositions are preferred. The concentration of the active agent solubilized in the composition preferably ranges from between about 0.5% and 35%, more preferably between about 0.5% and 25%, even more preferably between about 1% and 17% and most preferably between about 6% and 17% by weight of the composition. These percentages by weight are calculated on an anhydrous metal salt base exclusive of water and any complexing agents such as glycine, glycine salts or other complexing agents. The active agent can be solubilized in the antiperspirant or deodorant composition with the aid of additional solvents or co-solvents which are known or otherwise effective to solubilize the antiperspirant active agent and which are compatible with the selected components of the antiperspirant composition or which otherwise they do not unduly harm the performance of the product. The antiperspirant active agent for use in the antiperspirant embodiments of the present invention includes any compound, composition or other material that has antiperspirant activity. Preferred antiperspirant actives include the astringent metal salts, especially the inorganic and organic salts of aluminum, zirconium and zinc, as well as mixtures thereof. Particularly preferred salts are the aluminum and zirconium salts, such as, for example, aluminum halides, aluminum chlorohydrate, aluminum hydroxyhalides, zirconyl oxyhalides, zirconyl hydroxyhalides and mixtures thereof. Preferred aluminum salts for use in the antiperspirant modalities include those corresponding to the formula: Al2 (OH) to Clb »x H20 where a is between approximately 2 and 5; the sum of a and b is approximately 6; x is between about 1 and 6; and where a, b, and x may not have integer values. Aluminum chlorohydroxides are particularly preferred, referred to as "basic hydrochloride 5/6", where a = 5 and "basic hydrochloride 2/3", where a = 4. The processes for preparing the aluminum salts are described in U.S. Patent No. 3,887,692 to Gilman, issued June 3, 1975; U.S. Patent No. 3,904,741 to Jones et al., issued September 9, 1975, U.S. Patent No. 4,359,456 to Gosling et al., issued November 16, 1982; and British Patent Specification No. 2,048,229 to Fitzgerald et al., published December 10, 1980, all are incorporated herein by reference. Mixtures of aluminum salts are described in British Patent Specification No. 1,347,950 to Shin et al., Published February 27, 1974, the disclosure of which is also incorporated herein by reference. Preferred zirconium salts for use in the antiperspirant modalities include those corresponding to the formula: ZrO (OH) 2-aCla'x H20 where a is between approximately 1.1 and 2.0; x is between about 1 and 8; and where a and x can both not have integer values. These zirconium salts are described in Belgian Patent No. 825,146 of Schmitz, issued August 4, 1975, the disclosure of which is incorporated herein by reference. Particularly preferred zirconium salts are those complexes that additionally contain aluminum and glycine, commonly known as ZAG complexes. These ZAG complexes contain aluminum chlorohydroxide and zirconyl hydroxy chloride corresponding to the formulas described above. These ZAG complexes are described in U.S. Patent No. 3,679,068 to Luedders et al., Issued February 12, 1974; British Patent Application No. 2,144,992 to Callaghan et al., published March 20, 1985; and the Patent of the. United States No. 4,120,948 to Shelton, issued October 17, 1978, all are incorporated herein by reference. The antiperspirant embodiments of the present invention may also be formulated to comprise other dispersed solids or other materials in addition to or instead of the particulate antiperspirant active agent. These other dispersed solids or other materials include any known or otherwise suitable material for topical application to human skin. The compositions of the present invention can also be formulated as cosmetic or topical compositions that do not contain antiperspirant or other active, or otherwise particulate material.

I. Deodorant Active The composition of the present invention includes deodorant moieties containing a deodorant active agent, perfume or combination thereof, at concentrations ranging from about 0.01% to 60%, preferably from about 0.01% to 20%, more preferably between about 0.01% and 10%, even most preferably between about 0.1% and 0.5% by weight of the composition. These active deodorants and perfumes include any known or otherwise effective active agent or perfume, suitable for topical application to human skin. Deodorant active agents for use in the deodorant embodiments of the present invention include any topical material that is known or otherwise effective to prevent or eliminate odors associated with perspiration. These deodorant active agents are typically antimicrobial agents (e.g., bacteriocides, fungicides), malodor absorbing materials, or combinations thereof. Preferred deodorant active agents are antimicrobial agents, non-limiting examples of which include cetyltrimethylammonium bromide, cetyl pyridinium chloride, benzethonium chloride, diisobutyl-phenoxy-ethoxy-ethyl-dimethyl-benzyl-ammonium chloride, sodium N-lauryl-sarcosine, N- sodium palcostyl sarcosine, lauroyl sarcosine, N-myristoyl glycine, potassium N-lauryl sarcosine, trimethylammonium chloride, sodium-aluminum chlorhydroxy lactate, triethyl citrate, tricetylmethyl ammonium chloride, 2, 4, 4'-diphenyl ether -2 '-hydroxy (triclosan), 3,4,4'-trichlorocarbanilide (trichlorocarbonate), diaminoalkyl amides, such as, for example, L-lysine hexadecyl amide, citrate heavy metal salts, salicylate and pyroctose, in particular zinc salts, and acids thereof, heavy metal salts of pyrithione, especially zinc pyrithione, zinc phenosulfate, farnesol, and combinations thereof. Preferred deodorant active agents are triclosan, triclocarban, and combinations thereof, wherein the preferred concentration of either triclosan or triclocarban ranges from about 0.01% to 1.0%, more preferably from about 0.1% to 0.5%, still from greater preference of between about 0.1% and 0.3% by weight of the composition, and wherein the total concentration of triclosan and triclocarban when used together in a composition ranges from about 0.01% to 2.0%, most preferably from about 0.2. % and 1.0%, still more preferred between about 0.2% and 0.6% by weight of the composition. Other deodorant active agents include odor absorbing materials, such as, for example, carbonate and bicarbonate salts, which include alkali metal, ammonium and tetraalkylammonium carbonates and bicarbonates. Sodium and potassium salts of these odor absorbing materials are preferred. Still other deodorant active agents include the antiperspirant actives described below. Perfumes suitable for use in the deodorant embodiments of the present invention include any topical material that is known or otherwise effective in masking the malodor associated with perspiration, or which otherwise provides the composition with the desired perfumed flavor. . These perfumes include any perfume or perfume chemical compound, including pro-perfumes and deso-perfumes, suitable for topical application to the skin.

The amount of concentration of the perfume in the deodorant modalities must be effective to provide the desired aroma characteristics or to mask the malodor, where the malodour is inherently associated with the composition itself or is associated with the development of malodor coming from of human perspiration. Perfumes are made by those skilled in the art in a wide variety of fragrances and concentrates. Typical perfumes and fragrances are described in Arctander, Perfume and Flavor Chemicals (Aroma Chemicals), Vol. I and II (1969); and Arctander, Perfume and Flavor Materials of Natural Origin (1960). U.S. Patent 4,322,308 and U.S. Patent 4,304,679, both incorporated herein by reference, disclose perfume or fragrance components as generally included in the manner of example: volatile phenolic substances (such as, for example, amyl salicylate, benzyl salicylate, and red thyme oil); essential oils (such as, for example, geranium oil, patchouli oil, and seed oil); citrus oils; extracts and resins (such as, for example, Siamese benzoin resinoid and opoponaco resinoid); "synthetic" oils (such as for example Bergamot 37 and 430, Geranium 76 and Pomeransol 314); aldehydes and ketones (such as, for example, B-methyl naphthyl ketone, p-t-butyl-A-methyl hydrocinnamic aldehyde and p-t-amyl cyclohexanone); polycyclic compounds (such as, for example, coumarin and ß-naphthyl methylether); esters (such as, for example, diethyl phthalate, phenylethyl phenylacetate, non-anolyte-1: 4). Perfumes also include esters and essential oils derived from floral materials and fruits, citrus oils, pure aldehydes, resinoids, musk notes and other animals (eg, natural isolates of civet, castoreum and musk), balsams, etc. and alcohols (such as, for example, dimyrcetol, phenylethyl alcohol and tetrahydromuguol). Examples of these useful components in the perfumes herein include decyl aldehyde, undecyl aldehyde, undecylenic aldehyde, lauric aldehyde, amyl cinnamic aldehyde, phenyl methyl ethyl glycidate, nonyl methyl acetaldehyde, myristic aldehyde, nonalactone, nonyl aldehyde, aldehyde octyl, undecalactone, hexyl cinnamic aldehyde, benzaldehyde, vanillin, heliotropin, camphor, para-hydroxy phenolbutanone, tet 6-acetyl 1,1,3,4,4,6-hexamethyl rahydronaphthalene, alpha-methyl ionone, gamma-methyloneone , and amyl-cyclohexanone, and mixtures of these components. Other suitable perfumes are those which mask or help to mask the odors associated with perspiration (hereinafter referred to as odor-masking fragrances), some non-limiting examples thereof are described in U.S. Patent 5,554,588, U.S. Pat. of the United States 4,278,658, United States Patent 5,501,805, and Patent Application EP 684 037 Al, all are hereby incorporated by reference in their entirety. Preferred odor masking perfumes are those having a Deodorizing Value of at least about 0.25, more preferably between about 0.25 and 3.5, still more preferably between about 0.9 and 3.5, as measured by the Deodorant Value Test described In the patent application EP 684 037 Al. The perfume for use herein may also contain solubilizers, diluents or solvents which are well known in the art. These materials are described in Arctander, Perfume and Flavor Chemicals (Aroma Chemicals), Vol. I and II (1969). These materials typically include small amounts of dipropylene glycol, diethylene glycol, C6C6 alcohols, and benzyl alcohol.

III. Volatile, non-polar hydrocarbon liquid The antiperspirant or deodorant compositions of the present invention comprise a non-polar hydrocarbon liquid, volatile at a concentration between about 1% and 60%, preferably between about 10% and 40%, more preferably between 20% to 40% by weight of the composition. The term "volatile", in the sense in which it is used in this context, refers to the non-polar, volatile hydrocarbon liquid and means that these materials are liquids under ambient conditions and have a vapor pressure as measured at 25 °. C of at least about 0.01 mmHg, preferably between about 0.01 mmHg and 6.0 mmHg, more preferably between about 0.01 mmHg and 2.0 mmHg, and preferably an average boiling point at a pressure atmosphere (1 atm) of less of approximately 250 ° C.

The term "non-polar", in the sense in which it is used in this context, refers to the non-polar, volatile hydrocarbon liquid and means that these materials have a solubility parameter of less than 7.5 (cal / cm3) 0 ' 5, more typically from about 5.0 (cal / cm3) 0.5 to less than 7.5 (cal / cm3) 0.5. These nonpolar, volatile hydrocarbon liquids preferably contain only hydrogen and carbon and therefore preferably contain no functional groups. The solubility parameters as used to characterize the non-polar, volatile hydrocarbon liquids, and any other materials desed herein are determined by methods well known in the chemical arts to establish the relative polar character of a solvent or other material. A destion of the solubility parameters and the means to determine them are desed by C.D. Vaughan, "Solubility Effects in Product, Package, Penetration and Preservation" 103 Cosmetics and Toiletries 47-69, October 1988; and C.D. Vaughan, "Using Solubility Parameters in Cosmetics Formulation", 36 J. Soc. Cosmetic Chemists 319-333, September / October 1988, the destions of which are incorporated herein by reference. The volatile, non-polar hydrocarbon liquid for use in the composition of the present invention is preferably a liquid paraffin and / or isoparaffin having the required volatility and non-polar character. The non-polar, volatile hydrocarbon liquids can have a cyclic, branched and / or chain configuration, and can be saturated or unsaturated, preferably saturated. Volatile non-polar hydrocarbon liquids are branched chain hydrocarbons having the required volatility and solubility parameter and having between about 6 and 40 carbon atoms, preferably between about 6 and 20 carbon atoms. These preferred hydrocarbon liquids will more typically be formulated as a combination of two or more of the branched chain hydrocarbons desed above, wherein the combination of the two or more hydrocarbons have molecular weights, number of carbon atoms, and / or carbon configurations. different chain. Specific non-limiting examples of these combinations include isoparaffins available from Exxon Chemical Company, Baytown, Texas U.S. A., as Isopar M (isoparaffin of C? 3-C?), Isopar C (Isoparaffin of C7-C8), Isopar E (Isoparaffin of C8-Cg), Isopar G (Isoparafin of C? On), Isopar L ( Isoparaffin of C11-C13), Isopar H (Isoparaffin of Cu-C? 2) and combinations thereof. Other non-limiting examples of suitable branched chain hydrocarbons include Permethyl 99A (C12, isododecane), Permethyl 101A (C16, isohexadecane), Permethyl 102A (C20, isoeicosane), and combinations thereof. The Permethyl series is available from Preperse, Inc., South Plainfield, New Jersey, U.S.A. Other non-limiting examples of suitable branched chain hydrocarbons include petroleum distillates, such as, for example, those available from Phillips Chemical such as Soltrol 130, Soltrol 150, Soltrol 170, and those available from Shell as Shell Sol-70, 71, and - 2033 Still other suitable isoparaffins include Cg-Cn Isoparaffin, C9-C13 Isoparaffin, C9-CX4 Isoparaffin, C? 0-C? 3 Isoparaffin, C12-C14 Isoparaffin, C? 3-C? 6 Isoparaffin, Isoparaffin of C? 4-C? e and hydrogenated polyisobutene available from Amoco as the Palane Series and from Fanning Corporation as the Fancor P. Series Non-limiting examples of other volatile, non-polar hydrocarbon liquids suitable for use in antiperspirant and deodorant compositions include paraffins such as dodecane, octane, dexade and combinations thereof and the Norpar series of paraffins available from Exxon Chemical Company such as Norpar-12, -13 and -15 and the Neosolve series of paraffins available from Shell. Yet another example includes C11-C15 alkanes / cycloalkanes, such as those available from Exxon such as Exxsol D80.

IV. Material for mitigating skin irritation The antiperspirant and deodorant compositions of the present invention comprise a material for mitigating skin irritation. (also referred to as "mitigating material"), wherein the weight ratio of the volatile, nonpolar hydrocarbon liquid, subsequently defined for the mitigating material is between about 5: 1 and 1:50, preferably between about 4: 1 and 1:10, more preferably between about 3: 1 and 1: 5, most preferably between about 2: 1 and 1: 1.

The mitigating material for use in the compositions of the present invention includes any material effective to reduce skin irritation caused by the volatile, non-polar hydrocarbon liquid component of the composition, wherein the reduction in skin irritation is determined in accordance with the methodology for skin irritation described herein. It has been found that for these mitigating materials to be effective they must have an equal or lesser vapor pressure, preferably lower than the vapor pressure of the non-polar hydrocarbon liquid, volatile in the composition (as measured at 25 ° C). It has also been found that the most effective of these mitigating materials are the non-volatile silicone fluids. It has been found that non-polar, volatile hydrocarbon liquids, as defined herein, cause skin irritation even when used at relatively low concentrations of between about 1% and 60% by weight of an antiperspirant and deodorant composition. It has also been found that mitigating materials as defined herein provide the composition of the present invention with the mitigation of the desired skin irritation, with the proviso that they are incorporated into the composition at vapor pressure and proportions. in weight related to the non-polar, volatile hydrocarbon liquid, selected. • The component of the mitigating material of the antiperspirant and deodorant compositions of the present invention may comprise one or more mitigating materials which individually or collectively are at a concentration of between about 1% and 60%, preferably between about 5% and 30%, more preferably between about 5% and 10% by weight of the composition. Any mitigating material of known or otherwise effective irritation may be used herein, provided that the mitigating material is formulated in the composition at the selected weight proportions defined above. It has been found that among these known or otherwise effective mitigating materials, non-volatile silicone fluids are especially effective in reducing or eliminating skin irritation caused by the use of low concentrations of volatile, non-polar hydrocarbon liquids. The mitigating materials can also be characterized as those materials that effectively reduce skin irritation from an antiperspirant or deodorant composition when evaluated according to the patch test for skin irritation accumulated for 7 days. The reduction of skin irritation is provided by a mitigating material when the mitigating composition shows a reduced degree of irritation LS compared to similar formulas wherein the mitigating material is replaced in the composition with water for aqueous compositions or cyclopentasiloxane for compositions anhydrous Preferred mitigating materials are non-volatile silicone-containing materials. Materials containing non-volatile silicone can be in the form of solids or liquids, preferably liquids, under ambient conditions. The preferred non-volatile silicone-containing materials are non-volatile silicone liquids, preferably having a viscosity as measured at 25 ° C of at least 5 centistokes, more preferably between about 10 centistokes and 1000 centistokes, still more preferably between about 10 centistokes and 100 centistokes, most preferably between about 30 centistokes and 80 centistokes. Other suitable but less preferred silicones include solicone solids (e.g., silicone waxes) and viscous silicone fluids (e.g., silicone gums). Non-limiting examples of silicone-containing mitigating materials suitable for use herein include polyalkylsiloxanes, polyalkylarylsiloxanes, polyalkylsilanol siloxanes (for example, dimethiconols) and polyethersiloxane copolymers, many examples of which are well known in the cosmetics and anti-aging arts. perspirants / deodorants, some of which are described in 1 Cosmetics, Science and Technology 27-104 (M. Balsam and E. Sagarin ed. 1972); and U.S. Patent No. 4,202,879, issued to Shelton on May 13, 1980; whose descriptions are incorporated herein by reference. Non-volatile, linear polydimethylsiloxane fluids are the preferred silicone-containing material for use in the antiperspirant and deodorant compositions of the present invention. Examples of these preferred silicone-containing fluids include Dow Corning 200, Rhodorsil Oils 70047 available from Rhone-Poulenc, Fluid Masil SF available from Mazer, Dow Corning 225; SF-96 and SF-1214, SF-1236 and CF-1251 Silicone Fluids (available from G.E. Silicones); Viscasil and gums such as GE SE 30 (available from General Electric Co.); and Silicone L-45, Silicone L-530, Silicone L-531 (available from Union Carbide) and Siloxane F-221 and Slicone Fluid S S-101 (available from SWS Silicones). Polyalkyl siloxanes siloxanes (e.g., dimethiconols such as DC1401, DC2-9023, DC4-2797, YF3800, GE88017, and mixtures thereof) have also been found to be especially effective when used in antiperspirant compositions containing gelling agents. relatively polar. These relatively polar gelling agents are described below and are those gelling agents that contain at least one highly polar functional group such as a carboxylic acid or functional agent with amide. It has been found that these silanol siloxanes provide a more stable composition than other silicone-containing materials when used in combination with relatively polar gelling agents and also provide irritation mitigation benefits in the skin when also used in combination with the liquid of non-polar, volatile hydrocarbon as defined herein. Preferred are polyalkylsilole siloxanes having between about 0.1% and 5.0% silanol content, preferably between about 0.5% and 5.0% silanol content and a viscosity between about 20 centistokes and 1000 centistokes, preferably between approximately 20 centistokes and 100 centistokes. Other non-limiting examples of suitable silicone-containing mitigating materials include silicone polyethers or silicone glycols (such as dimethicone copolyol or dimethiconol); polyethers linked with silicone alkyl (such as cetyl dimethicone copolyol Goldschmidt EM-90 or EM-97); siloxane surfactants of a hanging / rake / comb configuration, silicone surfactants of a trisiloxane configuration and silicone surfactants of ABA / alpha-omega block copolymers (such as, for example, polyoxyalkylenes, polyoxyethylene or polyoxyethylene / polyoxypropylene ethoxylated or ethoxylated / propoxylated ); silicone emollients substituted with aromatic groups (for example, phenyl, alpha-methyl styryl, styryl, methylphenyl, alkylphenyl); silicone copolymers with other functional groups including: hydrogen, alkyl, methyl, amino, trifluoropropyl, hydroxyl, vinyl, alkoxy, arylalkyl, aryl, phenyl, styryl, polyethers, esters, carboxylic compounds; alkylmethylsiloxanes or silicone waxes (for example, hexyl, octyl, lauryl, cetyl, stearyl); nonionic functional siloxane copolymers with terminal groups which are silanol or trimethylsiloxy; nonionic functional siloxanes with main structure groups which are linked with trisiloxane or methicone; nonionic silicone surfactants; tetraethoxysilane; tetramethoxysilane; hexametoxy silicone; oximetoxitrisiloxane; silicone emulsifiers; siloxane or silicone resins; alkyl silicone resins; polyoxyalkylene silicone resins; MQ resins such as GE SS4267, GE SS4230 and Shi seido / Shin-et su, for example, Japanese Patent Publication JP86143760 or Walker Chem. 6MBH (described in EP722970); alkoxy s i loxanes; alkoxysilanes; methicones; and combinations thereof. Non-limiting examples of other suitable silicone-containing mitigating materials include those available from Dow Corning: DC-556, Cosmetic Grade Fluid (phenyl trimethicone); DC-704 Diffusion Pump Fluid (Tetramethyl-Tetraphenyl-Trixiloxane); DC-705 Diffusion Pump Fluid; DC-1784 Emulsion; DC-AF Emulsion; DC-1520-US Emulsion; DC-593 Fluid (Dimethicone [and] Trimethylsiloxysilicate); DC-3225C Fluid (Cyclomethicone [and] Dimethicone copolyol); DC-190 Fluid (Dimethicone Copolyol); DC-193 Fluid (Copolyol dimethicone); DC-5200 Fluid (Copolyol lauryldimethicone); DC-6603 Polymer powder; Volatile linear dimethicones; DC-5640 Powder; DC-Q2-5220 (Dimethicone Copolyol); DC Q2-5324 (Dimethicone Copolyol); DC-2501 Cosmetic Wax (Dimethicone Copolyol); DC-2502 Fluid (Cetil Dimethicone); DC-2503 Wax (Stearyl Dimethicone); DC-1731 Volatile Fluid (Caproil Trimethicone); DC-580 Wax (Stearoxytrimethylsilane [and] stearyl alcohol); DC-1-3563 (Dimethiconal); DC-X2-1286 (Dimeticonol); DC-X2-1146A (Cyclomethicone [and] Dimethiconol); DC-8820 Fluid (amino with functional group); DC Q5-0158A wax (stearoxitrimethylsilane); DC Q2-8220 (Trimet ilsilylamodimethicone); DC 7224 (Trimethylsilyllamodimethicone); DC-X2-1318 Fluid (Cyclomethicone [y] Vinylimetone icone); DC-QF1-3593A fluid (Trimethylsiloxysilicate); dimethicone behenoxy; Bisphenil hexa methicone; C24-C2e alkyl methicone; C30-C 5 alkyl methicone; detyldimethicone; dimethicone gums; copolyol dimethicone acetate; dimethicone copolyol butyl ether; dimethicone methylether copolyol; diphenyl dimethicone; stearoxi dimethicone; stearoxi met icone / dimethicone copolymer; stearyl methicone; triphenyl trimethicone and combinations thereof. Other non-limiting examples of suitable silicone-containing mitigating materials include those available from General Electric: GE CF-1023 (Dimethyl-diphenyl-siloxane); GE CF-1142 (Methylphenyl) Siloxane Fluid); GE CF-1153 (Dimethyl-Diphenyl-Siloxane); GE SF-1265 (Diphenyl-Dimethyl-Siloxane); GE SF-1328; GE SF-1188 (Dimethicone Copolyol); GE SF-1188A (Poiieter silicone copolymer); GE SF-1288 (polyether silicone copolymer, 3-hydroxypropyl dimethyl-methyl ethoxylate); GE SF-1318 (Methylester siloxane); GE SF-1328 (silicone surfactant, 3- • hydroxypropyl dimethyl-methyl ethoxylated-propoxylated); GE SF-1550 (methylphenyl siloxane, hexamethyl-3-phenyl-3- [[trimethylsilyl] oxy] trisiloxane); GE SF-1632 (silicone wax); GE SS-4267 (Dimethicone [and] Trimethylsiloxysilicate) and combinations thereof. Other non-limiting examples of suitable silicone-containing mitigating materials include those available from Goldschmidt: Abil EM-90 (silicone emulsifier); Abil EM-97 (polyether siloxane); Abil waxes such as the Abil B 88 series and Abil 9810 wax (silicone wax or C24-28 metycone); Wax Abil 2434 (Stearoxi Dimethicone); Wax Abil 9800D (Stearil Dimethicone); Tegomer H-Si 2111, H-Si 2311, A-Si 2120, A-Si 2320, C-Si 2141, C-Si 2341, E-Si 2130, E-Si 2330, V-Si 2150, V-Si 2550 , H-Si 6420, H-Si 6440, H-Si 6460 (Copolymers of Dimethicone Alpha-Omega) and combinations thereof. Other non-limiting examples of suitable silicone-containing mitigating materials include those available from Masil 756 from PPG Industries (Tetrabutoxypropyl Trisiloxane); bis-phenylhexamethicone (available as Silbione Oils 70633 V30 from Rhone-Poulenc); Silbione oils 70646 (dimethicone copolyols from Rhone-Poulenc); Silicone L-711, L-720, L-721 and L-722 (dimethicone copolyols from Union Carbide); Silicone L-7000, L-7001, L-7002, L-7004, L-7500, L-7600, L-7602, L-7604, L-7605 and L-7610 (Dimethicone copolyols from Union Carbide); Unisil SF-R (UPI dimethiconol); Olin Silicate Clod (Tris [Tributoxyloxy] Methylsilane); Siloplane fluids (available from Chisso Corp.); silicone copolymer F-754 (dimethicone copolyol from SWS Silicones); Silwaxes de Siltech; Fluid L series of Wacker Silicone (available from Wacker Silicone) and combinations thereof. Other non-limiting examples of suitable non-volatile silicones include those described in WO 97/16162 and WO 97/16161, both published May 9, 1997, and both descriptions are incorporated herein by reference. Other mitigating materials, although less preferred, are organic emollients that do not contain silicone, including petrolatum, lanolin, acetylated lanolin, hydroxylated lanolin, sucrose polyesters, cholesterol hydroxy stearate and combinations thereof. Among the emollients that do not contain silicone, the most preferred ones are fairly occlusive materials such as petrolatum.

V. Optional carriers The antiperspirant and deodorant compositions of the present invention may further comprise one or more carriers in addition to the non-polar, volatile hydrocarbon liquid and mitigating materials described below. Preferred optional carriers are carriers of volatile silicone. These volatile silicones will usually have a viscosity as measured at 25 ° C of less than 10 centistokes, and may have cyclic, linear or branched configurations, non-limiting examples thereof being described in Todd et al., "Volatile Silicone Fluids for Cosmetics ", Cosmetics and Toiletries, 91: 27-32 (1976), whose descriptions are incorporated herein by reference. The optional volatile silicone carrier is preferably a cyclic silicone and preferably has between about 3 and 7, more preferably between about 4 and 5 silicon atoms. Most preferred are those volatile cyclic silicones corresponding to the formula: wherein n is between about 3 and 7, preferably, between about 4 and 5, more preferably 5 (cyclopentasiloxane). Volatile silicones suitable for use herein include, but are not limited to: cyclopentaxiloxane (commercially available from G.E. Silicones); Dow Corning 244 and Dow Corning 245 (commercially available from Dow Corning Corp.); GE 7207; GE 7158 and Silicone Fluids SF-1202 and SF-1173 (obtained from General Electric Co.); SWS-03314, SWS-03400, F-222, F-223, F-250, F-251 (available from SWS Silicones Corp.); Volatile Silicones 7158, 7207, 7349 (available from Union Carbide); Masil SF-V (available from Mazer) and combinations thereof. The optional liquid carrier may comprise other organic or non-organic, volatile or non-volatile, polar or non-polar carriers, the carrier material is known to be used in the anti-perspirant / deodorant or other personal care product, or is otherwise Safe and effective for topical application to human skin, other non-polar, volatile hydrocarbon liquid materials and to mitigate irritation are disclosed herein. Examples of these other optional liquid carriers include those described in U.S. Patent 5,750,096 (Guskey); U.S. Patent 5,733,534 (Sawin et al.); U.S. Patent 5,718,890 (Putman et al.); U.S. Patent 5,429,816 (Hofrichter et al.); U.S. Patent 5,605,681 (Trandai et al.); and U.S. Patent 5,585,092 (Trandai et al.), the disclosures of which are incorporated herein by reference.

SAW . Suspension or Thickener Agent The antiperspirant and deodorant compositions of the present invention may further comprise a suspending or thickening agent to assist in providing the composition with the desired viscosity, rheology and texture or hardness of the product, or otherwise assist in suspending any solids or liquids dispersed within the composition. The terms "suspending agent" and "thickening agent" are used interchangeably herein and include any material known or otherwise effective to provide suspending, gelling, visifying, solidifying or thickening properties to the composition, or otherwise provide structure to the final product form. These suspending agents or thickeners include gelling agents and thickening or viscosity imparting agents polymeric or non-polymeric or inorganic. These materials will more typically include organic solids, silicone solids other than the silicone mitigating materials described herein, crystalline inorganic particulates or other gelling agents such as, for example, clays or silicas or combinations thereof. The concentration and type of optional suspension agent or thickener selected for use in the antiperspirant composition will vary depending on the desired product form, viscosity and hardness. For most suitable suspending or suspending agents to be optionally used herein, the concentration of these suspending agents or thickeners will more typically vary between about 0.1% and 35%, more typically between about 0.1% and 20% by weight of the composition. Suitable gelling agents for use as optional suspending agents or thickeners in antiperspirant or deodorant compositions include, but are not limited to: fatty acid gelling agents, acid salts, hydroxy acids, hydroxy acid gelling agents, fatty acid esters and amides or hydroxy fatty acid gelling agents, materials terol boils, dibenzylidene alditols, lanolinol materials, fatty alcohols, triglycerides, sucrose esters such as SEFA behenate, inorganic materials such as clays or silicas and other amide or polyamide gelling agents. Suitable gelling agents include fatty alcohols having from about 8 to 40 carbon atoms, preferably from about 8 to 30 carbon atoms, more preferably from about 12 to 18 carbon atoms. These gelling agents are wax-like materials that are more typically used at concentrations ranging from about. 1% and 25%, preferably between about 5% and 20%, more preferably between about 10% and 20% by weight of the antiperspirant composition. Preferred are cetyl alcohol, myristyl alcohol, stearyl alcohol and combinations thereof, stearyl alcohol is more preferred. Other suitable gelling agents include waxes or wax-like materials having a melting point above 65 ° C, more typically between about 65 ° C and 130 ° C, examples of which include, but are not limited to: waxes such as example, beeswax, carnauba, myrtle, candelilla, montan, ozocerite, ceresin, hydrogenated castor oil (castor wax), synthetic waxes, microcrystalline waxes. Castor wax is preferred within this group. Other waxes with high melting point are described in U.S. Patent 4,049,792 to Elsnau, issued September 20, 1997, the disclosure of which is incorporated herein by reference. Other suitable gelling agents include fatty acid gelling agents such as, for example, fatty acid and hydroxy or alpha hydroxy fatty acids, having between about 10 and 40 carbon atoms and esters and amides of these gelling agents. Non-limiting examples of these gelling agents include 12-hydroxystearic acid, 12-hydroxylauric acid, 16-hydroxohexadecanoic acid, behenic acid, euric acid, stearic acid, caprylic acid, lauric acid, isostearic acid and combinations thereof. Preferred are 12-hydroxystearic acid, esters of 12-hydroxystearic acid, amides of 12-hydroxystearic acid and combinations thereof, and all other gelling agents corresponding to the following formula: wherein Ri is OR2, NR2R3, or a portion containing silicone; and R2 and R3 are hydrogen, or an alkyl, aryl or arylalkyl radical that is branched, linear or cyclic and has between about 1 and 22 carbon atoms; preferably, between about 1 and 18 carbon atoms. R2 and R3 may be either the same or different; however, preferably, at least one is a hydrogen atom. Among these preferred gelling agents are those selected from the group consisting of 12-hydroxystearic acid, 12-hydroxystearic acid methyl ester, 12-hydroxystearic acid ethyl ester, 12-hydroxystearic acid stearyl ester, 12-hydroxystearic acid benzyl ester, 12-hydroxystearic acid amide. hydroxystearic acid, isopropyl amide of 12-hydroxystearic acid, 12-hydroxystearic acid butylamide, 12-hydroxy stearic acid, benzylamide, 12-hydroxystearic acid, 12-hydroxystearic acid t-butylamide, 12-hydroxystearic acid cyclohexylamide, 1- adamantylamide of 12-hydroxystearic acid, 2-adamantyl uramide of 12-hydroxyhydroxy-5-hydroxy stearate, diisopropylamide of 12-hydroxyl-tertiary acid, and mixtures thereof; even more preferred, 12-hydroxyl tertiary acid, 12-hydroxyl tertiary isopropylamide, and combinations thereof. The 12-hydroxyl tertiary acid is more preferred. Suitable amide gelling agents include disubstituted or branched mknoamide gelling agents, monosus tethered or branched diamide gelling agents, triamide gelling agents and combinations thereof, including n-acyl amino acid derivatives such as, for example, amino acid amides of n-acyl, n-acyl amino acid esters prepared from glutamic acid, lysine, glutamine, aspartic acid and combinations thereof. Other suitable amide gelling agents are described in U.S. Patent 5,429,816, issued July 4, 1995 and U.S. Patent Application Serial Number 08 / 771,183, filed December 20, 1996, which descriptions are incorporated herein by reference. The concentrations of all these gelling agents preferably range from about 0.1% to 25%, preferably from about 1% to 15%, most preferably from about 1% to 10% by weight of the antiperspirant composition. Other suitable gelling agents include triglyceride gelling systems comprising glyceryl tribehenate and other triglycerides, wherein at least about 75%, preferably about 100%, of the esterified fatty acid portions of these other triglycerides each have between about 18 and 36 carbon atoms and wherein the molar ratio of glyceryl tribehenate to these other triglycerides is between about 20: 1 and 1: 1, preferably between about 10: 1 and 3: 1, more preferably between about 6: 1 and 4: 1. The esterified fatty acid portions can be saturated or unsaturated, substituted or unsubstituted, linear or branched, although preferably linear, saturated, unsaturated portions derived from fatty acid materials having between about 18 and 36 carbon atoms. The triglyceride gelling material preferably has a melting point of less than about 110 ° C, preferably between about 50 ° C and 110 ° C. The preferred concentrations of the triglyceride gelling systems described above range from about 0.1% to 20%, most preferably from about 0.5% to 15% by weight of the antiperspirant composition. For roll-on formulations having a penetration force value of between about 20 grams • force and 100 grams • force, the triglyceride concentrations preferably range from about 1% to 5% by weight of the antiperspirant composition. For other cream formulations, including those formulations suitable for use in cream applicator devices, having a penetration force value of between about 100 grams • force and 500 grams • force, triglyceride concentrations preferably range from about 4 % and 20%, more preferably between about 4% and 10% by weight of the antiperspirant composition. Specific examples of triglyceride gelling agents for use in commercially available antiperspirant compositions include, but are not limited to: tries tearin, hydrogenated vegetable oil, trihydroxysterin (Thixcin® R, available from Rheox, Inc.), rapeseed oil, wax of castor oil, fish oils, tripalmiten, Syncrowax® HRC and Syncrowax® HGL-C (Syncrowax® available from Croda, Ine.). Other suspending agents or thickeners suitable for use in antiperspirant and deodorant compositions include suspending agents or particulate thickeners such as, for example, colloidal pyrogenic silica clays and pigments. Other known or otherwise effective suspension agents or particulate thickeners can also be used in the antiperspirant composition. The concentrations of optional particulate thickeners preferably range from about 0.1% to 15%, more preferably from about 1% to 15%, even more preferably from about 1% to 8% by weight of the composition. Colloidal pyrogenic silica pigments are preferred, a common example of which includes Cab-O-Sil®, a submicroscopic pyrogenic particulate fumed silica. Suitable clay suspending agents or thickeners include montmorillonite clays, examples of which include bentonites, hectorites and colloidal magnesium aluminum silicates. These and other suitable clay suspending agents are preferably hydrophobically treated, and when so treated in general they will be used in combination with a clay activating agent. Non-limiting examples of suitable clay activators include propylene carbonate, ethanol and combinations thereof. The amount of the clay activator will typically vary between about 25% and 75% by weight of the clay, more typically between about 40% and 60% by weight of the clay. The thickening or gelling agents for the deodorant embodiments of the present invention are salts of fatty acids, wherein the fatty acid portion has between about 12 and 40 carbon atoms, preferably between about 12 and 22 carbon atoms, more preferably between about 16 and 20 carbon atoms, most preferably about 18 carbon atoms. Salt forming cations suitable for use with these gelling agents include metal salts such as alkali metals, for example, sodium and potassium, and alkaline earth metals, for example, magnesium and aluminum. Sodium and potassium salts are preferred, more preferably sodium stearate, sodium palmitate, potassium stearate, potassium palmitate, sodium myristate, aluminum monostearate, and combinations thereof. The most preferred is sodium stearate.

VII. Other optional materials The antiperspirant and deodorant compositions of this invention may further comprise one or more optional materials that are known to be used in the antiperspirant, deodorant or other personal care product. Non-limiting examples of these other optional materials include dyes or colorants, emulsifiers, perfumes, dispensing agents, pharmaceuticals or other topical active agents, preservatives, surfactants, process aids such as viscosity modifiers and wash-off aids. Examples of these optional materials are described in U.S. Patent No. 4,049,792 to Elsnau, issued September 20, 1977; U.S. Patent No. 5,019,375 to Tanner et al., issued May 28, 1991; and U.S. Patent No. 5,429,816 to Hofrichter et al., issued July 4, 1995, the disclosures of which are incorporated herein by reference. The antiperspirant embodiments of this invention preferably comprise a combination of volatile and non-volatile silicone materials as described in U.S. Patent 5,156,834 (Beckmeyer et al.). These modalities can be formulated in any product form, for example, solid, liquid or semi-solid.

VIII. Form of the product The antiperspirant and deodorant compositions of. The present invention can be formulated as any known product form or otherwise effective to provide a topical application of the antiperspirant or deodorant active agent to the desired area of the skin. Non-limiting examples of these product forms include liquids, solids (gel solids, solid bars, suspensoids) and solids / creams / soft semi-solids, lotions, aerosols and sprays without spray, roll-ons, etc. The antiperspirant embodiments of the present invention are preferably in the form of solids or soft creams and more preferably a solid or soft cream containing the materials described or otherwise claimed in U.S. Patent 5,156,834 (Beckmeyer et al. ) and / or U.S. Patent 5,718,890 (Putman et al.), the disclosures of which are incorporated herein by reference. All antiperspirant embodiments of the present invention, regardless of the product form, preferably contain the combination of volatile and non-volatile silicones as described in U.S. Patent 5,156,834 (Beckmeyer et al.).

IX. Manufacturing Methods The antiperspirant and deodorant compositions of the present invention can be prepared by any known or otherwise effective technique suitable for providing an antiperspirant or deodorant composition of the desired form and having the essential materials described herein. Many of these techniques are described in the antiperspirant techniques and for formulation for each of the described product forms.

X. Method of use The antiperspirant and deodorant compositions can be applied topically to the armpit or other area of the skin in an effective amount to treat or reduce moisture of perspiration and / or odor. The composition preferably is applied in an amount ranging from about 0.1 grams to 20 grams, of higher preference between about 0.1 grams and 10 grams, even more preferably between 0.1 grams and 1 gram, to the desired area of the skin . Preferably, the compositions are applied to the armpit or other area of the skin, once or twice a day, preferably once a day, to achieve effective antiperspirant and / or odor control for a prolonged period.

XI. USES The following non-limiting examples illustrate specific antiperspirant and deodorant modalities of the present invention, including non-limiting examples of the methods of manufacture and use. Each of the compositions of the examples is prepared by methods well known in the art of formulating to prepare the various forms of antiperspirant and deodorant product. All amounts of the examples are presented in percentages by weight based on the total weight of the antiperspirant or deodorant composition, unless otherwise specified.

EXAMPLES 1-7 The compositions described in Table 1 are antiperspirant compositions in the form of solids / semi-solids / soft creams. These compositions of the examples can be prepared by methods well known in the art for preparing these product forms, examples of these methods include those described in U.S. Patent 5,718,890 (Putman et al.) And the Patent Application of US Pat. United States Series No. 08 / 738,631 (Bretzler et al.), The disclosures of which are incorporated herein by reference.

Table 1 - Solids / semi-solids / soft anti-perspirant creams EXAMPLES 8-12 The compositions described in Table 2 are antiperspirant compositions. in the form of solid bars. These exemplary compositions can be prepared by methods well known in the art for preparing these product forms, examples of these methods include those described in U.S. Patent 4,985,238 (Tanner et al.), The disclosures of which are incorporated herein by reference. as reference.

EXAMPLES 13-18 The compositions described in Table 3 are antiperspirant compositions in the form of aerosols and liquid in roll-on. Each of these exemplary compositions can be prepared by methods well known in the art for preparing these product forms, examples of these methods include those described in U.S. Patent 4,904,463 (Johnson et al.) And the U.S. Patent. United 5,298,236 (Orr et al.), The descriptions of which are incorporated herein by reference.

EXAMPLES 19-23 The compositions described in Table 4 are antiperspirant compositions in the form of solid gel sticks. These compositions contain gelling agents as suspending agents, wherein the suspending agents contain polar functional groups (eg, carboxylic acid amide). The selected suspending agents are N-lauryl-glutamic acid, 12-hydroxystearic acid and di-n-butyl amide. Each of these exemplary compositions described in Table 4 will be prepared by methods well known in the art for preparing these product forms, examples of these methods include those described in U.S. Patent 5,429,816 (Hofrichter et al.), whose descriptions are incorporated herein by reference.

EXAMPLES 24-25 The compositions described in Table 5 are deodorant stick compositions. Each of these exemplified compositions can be prepared by methods well known in the art to prepare these product forms, examples of which include those described in U.S. Patent 5,605,681 (Trandai et al.) And U.S. Pat. 5,585,092 (Trandai et al.), The descriptions of which are incorporated herein by reference.

EXAMPLES 26-27 The compositions described in Table 6 are antiperspirant suspensions / emulsions. Each of these exemplary compositions can be prepared by methods well known in the art for antiperspirant emulsion compositions.

Table 6 - Antiperspirant emulsion The compositions as described in Tables 1-6 (Examples 1-27) are applied topically to the armpit once or twice daily in an amount sufficient to provide antiperspirant and / or deodorant efficacy, and are applied topically in accordance with methods described herein. The applied compositions have a dry feeling on the skin during and after application and cause little or no skin irritation.

XII. Skin Irritation Data The antiperspirant / deodorant compositions described in Table 7 were tested for skin irritation by a standard 7-day cumulative patch test. The results of the patch test are also shown in Table 7.

Table 7-Study for skin irritation for 7 days cumulative The formulations identified in Examples 28-31 in Table 7 are evaluated for skin irritation potential in human subjects according to a 7-day cumulative patch test protocol. This test is well known and is commonly used in the industry to assess materials and products for skin irritation potential. Each of these test samples (Examples 28-31) is applied to the upper outer part of the arms either right or left or in the back, under conditions of stops for 7 days, in periods of 23 hours. There is a minimum of 30 subjects for each test sample. The patches were removed from each subject in approximately 23 hours after applying the patch daily and a new patch was applied, after the application site was graduated for irritation. The sites of the patch graduated approximately one hour after the removal of each patch daily. The sites of the patch were graduated and an average grade LS for each sample was calculated. The degrees of skin irritation were based on the following scale from 0 to 4 described in Table 8.

Table 8-Graduation of patch test for skin irritation The data set forth in Table 7 show that non-polar, volatile hydrocarbon liquids (for example C? 3-Cj4 Isoparaffin) are irritant when applied to the skin from an anti-perspirant / deodorant composition (Example 31-grade LS medium 1.159 ± 0.037) and that the mitigating materials (for example, 10 cs dimethicone) can be used to reduce or eliminate skin irritation from these compositions (Examples 28-30 - average LS degrees of 0.279, 0.607, 0.899, all ± 0.037). As shown in Table 7, the degrees of skin irritation of Examples 28-30 containing a mitigating material are all less than the degree of skin irritation for Example 31 that does not contain mitigating material.

Claims (34)

1. An antiperspirant / deodorant composition comprising: (a) between about 0.01% and 60% by weight of an antiperspirant / deodorant active agent selected from the group consisting of the antiperspirant active agent, the deodorant active agent, perfumes and combinations thereof; (b) between about 1% and 60% by weight of a volatile, non-polar hydrocarbon liquid having a solubility parameter of less than about 7.5 (cal / cm 3) 0.5 and a vapor pressure as measured at 25 ° C of between approximately 0.01 mmHg and 6.0 mmHg; and (c) between about 1% and 60% by weight of a mitigating material having a vapor pressure equal to or less than the vapor pressure of the volatile, nonpolar hydrocarbon liquid; wherein the weight ratio of the non-polar, volatile hydrocarbon liquid to the mitigating material is between about 5: 1 and 1:50.

2. The composition according to claim 1, wherein the active agent is an antiperspirant active agent comprising an aluminum salt.

3. The composition according to claim 2, wherein the composition comprises between about 5% and 35% by weight of an aluminum-zirconium polymer as an antiperspirant active agent.

4. The composition according to claim 1, wherein the composition comprises a deodorant active agent selected from the group consisting of antimicrobial agents, deodorant perfumes, malodor absorbing materials and combinations thereof.

5. The composition according to claim 4, wherein the composition comprises between about 0.01% and 10% by weight of an antimicrobial agent.

6. The composition according to the claim 5, wherein the composition comprises between about 0.01% and 1.0% by weight of an antimicrobial agent selected from the group consisting of triclosan, triclocarban and combinations thereof.

7. The composition according to the claim 1, wherein the composition comprises between about 5% and 30% by weight of the mitigating material.

8. The composition according to the claim 1, wherein the weight ratio of the non-polar, volatile hydrocarbon liquid to the mitigating material is between about 3: 1 and 1: 5.

9. The composition according to the claim 1, wherein the mitigating material is non-volatile silicone.

10. The composition according to claim 9, wherein the non-volatile silicone is a silicone liquid selected from the group consisting of a polydimethylsiloxane, dimethiconol and combinations thereof.

11. The composition according to claim 10, wherein the non-volatile silicone liquid is a polydimethylsiloxane having a viscosity as measured at 25 ° C of between about 5 centistokes and 1,000 centistokes.

12. The composition according to claim 1, wherein the non-polar, volatile hydrocarbon liquid is a branched chain hydrocarbon having from about 4 to 40 carbon atoms.

13. The composition according to claim 12, wherein the branched, volatile chain hydrocarbon has a solubility parameter of between about 5.0 and 7.5 (cal / cm3) 0.5 and a vapor pressure of between about 0.01 mmHg and 2.0 mmHg at 25 ° C.

14. The composition according to claim 12, wherein the non-polar, volatile hydrocarbon is selected from the group consisting of isododecane, isohexadecane, isoeicosane and combinations thereof.

15. The composition according to claim 13, wherein the composition comprises a combination of two or more volatile branched chain hydrocarbons, having different molecular weights, each of which also has between about 6 and 20 carbon atoms.

16. The composition according to claim 15, wherein the branched chain / volatile hydrocarbon is selected from the group consisting of C? 3-C? Isoparaffin? / Isoparaffin of C7-C8, Isoparaffin of C3-Cg, Isoparaffin of C? O-Cp, Isoparaffin of Cn-C13, Isoparaffin of Cn-C12, Isoparaffins of C? -C? 8 and combinations thereof.

17. The composition according to claim 1, wherein the composition further comprises a volatile silicone according to the formula: wherein n is between about 3 and 7

18. The composition according to claim 1, wherein the mitigating material comprises a silicone-free emollient selected from the group consisting of petrolatum, glycerin, sucrose polyesters and combinations thereof.

19. The composition according to the claim 1, wherein the composition further comprises between about 0.1% and 35% by weight of a suspending agent.

20. The composition according to claim 19 wherein the composition is a deodorant composition comprising between about 0.1% and 35% of a C? 2 to C 40 fatty acid salt as a suspending agent.

21. The composition according to claim 20, wherein the fatty acid salt is sodium stearate.

22. The composition according to claim 9, wherein the composition further comprises a volatile silicone.

23. The composition according to claim 1, wherein the composition is in the form of a semi-solid.

24. The composition according to claim 1, wherein the composition is in the form of an aerosol spray.

25. The composition according to claim 1, wherein the composition is in the form of a solid stick.

26. The composition according to claim 19, wherein the suspending agent contains a polar functional group and the mitigating material is a polyalkyl silanol siloxane.

27. The composition according to claim 26, wherein the suspending agent is selected from the group consisting of suspending agents containing at least one carboxylic acid functional group, suspending agents containing at least one amide functional group and combinations thereof , and the polyalkylating material silanol siloxane is dimethiconol.

28. The composition according to claim 27, wherein the dimethiconol has a silanol content of between about 0.1% and 5.0% silanol and a viscosity of between about 20 centistokes and 1000 centistokes.

29. The composition according to the claim 28, wherein dimethiconol has a viscosity of between about 20 centistokes and 100 centistokes.

30. The composition according to claim 29, wherein the suspending agent comprises 12-hydroxystearic acid.

31. A method for treating or reducing moisture by perspiration and malodour, which comprises applying between about 0.1 grams and 20 grams of the composition according to claim 2 to the desired skin area.

32. The method for treating or reducing odor by perspiration moisture, which comprises applying between 0.1 grams and 20 grams of the deodorant composition according to claim 4 to the desired area of the skin.

33. The method for topically applying an antiperspirant composition containing a volatile, nonpolar hydrocarbon liquid to minimize skin irritation, the method comprises applying between about 0.1 grams and 20 grams of the composition, according to claim 2 .

34. The method for topically applying a deodorant composition containing a volatile, nonpolar hydrocarbon liquid to minimize skin irritation, the method comprises applying between about 1.1 grams and 20 grams of the composition, according to claim 4 .