MXPA00006989A

MXPA00006989A - Indicating device for use with a dispensing device

Info

Publication number: MXPA00006989A
Application number: MXPA/A/2000/006989A
Authority: MX
Inventors: Richard Blacker; Daniel K Engelbreth; James N Schmidt
Original assignee: 1263152 Ontario Inc
Priority date: 1998-01-16
Filing date: 2000-07-14
Publication date: 2002-03-26

Abstract

An indicating device for use with a dispensing device that dispenses metered dosages of a medicament from a container (100) having a valve (110) moveable between an open and closed position. In a preferred embodiment, the container (100) is reciprocally moveable within the housing (10) along a longitudinal axis. The housing (10) preferably has a well (18) adapted to receive a valve stem (110) and an exhaust port (26). The well (18) communicates with the port (26) such that the metered dosage of medicament is dispensed through the port (26) when the valve (110) is moved to the open position. An indicator assembly comprises an indicator member (50) that includes dosage indicia (66) visible to a user. In a preferred embodiment, the indicator assembly is provided in an indicator module (120). A method for dispensing measured dosages is also provided, along with a kit capable of being assembled as an inhalation device. A delivery system having a key member (300) and a key entry passageway is also provided.

Description

INDICATOR DEVICE FOR USE WITH A ASSORTMENT DEVICE This application is a partial continuation of the application with serial number 09 / 008,184 filed on January 16, 1998 and entitled "Aerosol Spout Device", the description of which is incorporated herein by reference. It is not intended to grant any license, express or implicit, to the application S.N. 09 / 008,184, or any patent arising therefrom, by virtue of incorporation by reference herein.

BACKGROUND OF THE INVENTION The present invention relates generally to an indicating device and in particular, to an indicating device for indicating the number of measured dosages of a substance and in particular a medicament, which has been stocked by or remaining in an assortment device. The delivery systems and in particular, assortment devices, have been developed to include a counting device or dose indicating device to indicate in number of measured doses of substance that have been dispensed from the delivery system or to indicate the number of doses that remain in it For example, patients have certain conditions that can be treated with medications dispersed in an aerosol and administered to the patient by inhalation. In one format, the aerosol and medicaments are contained in a container and are dispensed in dosages counted or measured with the dispensing device, which may include an actuator sleeve. In this provision, it may be important for the patient to be able to inquire the number of measured dosages that remain in the container, either by means of an indication of the number remaining in the container or by knowing the number already filled therein, so that the patient Do not be surprised with an empty container when you need the medication. Thus, it may be important that the dispensing device provides an accurate indication of either the number of doses remaining in the container or the number of doses already filled therein. Typically, a conventional aerosol container includes a body and a valve stem which can sink relative to the body to deliver the measured dose of aerosol and medicament. Typically, the container is provided with a predetermined number of doses measured, for example, in the order of approximately 200, so that the count of the number of depressions of the valve stem and the corresponding number of metered doses dispensed, can be directly correlated with the number of doses that remain in the container. In operation, the container is normally received within a housing of the dispensing device, wherein the valve engages a support block in the housing. The user administers the medicament by moving the container relative to the housing to sink the valve stem and internal valve and thereby release a metered dose, which is typically administered to the user through a port or nozzle extending from the accommodation. In an alternative delivery system, the measured dose can be first discharged into a chamber and then administered to the patient. After the metered dose is discharged from the container, the valve stem, which is normally spiral loaded, deflects the container away from the support block to move the container again relative to the housing. In this way, a metered dose of medication is discharged through each cycle of linear reciprocal movement of the container in relation to the housing. Some dispensing devices have indicating devices that convert the linear reciprocal movement of the container relative to the housing in a one-way or single-cycle movement of an indicator, wherein the indicator identifies the relative filling of the container, the number of measured doses remaining in the same or the number of doses already administered. Although these dispensing devices with indicators have provided the advantage of being generally able to keep track of the number of dosages, there is room for improvement. For example, indicating devices of this nature can include complex moving parts, which can be difficult to assemble and which are expensive to manufacture. Such devices may also be susceptible to counting deficiencies due to the configuration of the matching or fitting parts, or require excessive amounts of space within the housing to accommodate the relatively large or numerous moving parts.

Others may even prevent or interfere with the flow of air and the medication that is dispensed from the inhalation device. Alternatively, some devices use electrical circuit systems to count or record dispersions. However, such devices can be relatively expensive to manufacture and typically require a power source which may be susceptible to damage in various environments, such as humidity conditions.

BRIEF DESCRIPTION OF THE INVENTION Briefly stated in one aspect, the invention is directed to a dispensing device having an indicating device. The dispensing device delivers measured dosages of a substance from a container having a valve movable between a closed position and an open position. The container delivers a measured metering when the valve, actuated by a valve stem, moves to the open position. In an exemplary embodiment, the dispensing device includes a housing adapted to support the container movable reciprocally within the housing along a longitudinal axis. The housing has a cavity adapted to receive the valve stem and an exhaust port. The cavity communicates with the port so that the measured dosage of substance is delivered through the port when the valve rod is moved to the open position.

In an embodiment of the indicator device, an indicator assembly includes a worm screw rotatably installed in the housing on an axis transverse to the longitudinal axis and responsive to the movement of reciprocal movement of the container within the housing such that the longitudinal movement of the container in relation to the housing, causes the worm to turn on its axis. An indicating element includes dosing indications visible to a user and a circular apparatus installed in the housing on an axis transverse to the axis of the worm and not parallel to the longitudinal axis. The circular device engages with the worm. In a preferred embodiment, the indicator assembly further includes a ratchet wheel installed rotatably in the housing and adapted to be responsive to reciprocal movement of the container relative to the housing along the longitudinal axis. The ratchet wheel is connected to the worm, so that the rotation of the ratchet causes the worm apparatus to rotate on its axis. Furthermore, an actuator element including an arm inside the housing and adapted to move in response to movement of the container and operably engage with the ratchet wheel so as to rotate the wheel in response to longitudinal movement of the container is installed. in relation to accommodation. Furthermore, in the first preferred embodiment, the indicator element includes an indicator wheel installed coaxially with the circular apparatus on an axis that defines the axis of rotation of the indicator element. The dosing signals are applied to a surface of the indicator wheel. In another embodiment of the indicator device, the housing comprises at least one gear element and the indicator assembly includes a plurality of indicator elements, which includes at least a first and a second indicator element. The plurality of indicator elements is installed coaxially in the housing. At least one of the first and second indicator elements includes an advancing element, while at least the other first and second indicating elements includes a plurality of teeth. In operation, the first indicator element rotates relative to the second indicator element so that the gear element selectively engages and deflects the advancing element toward operable gear with at least one of the plurality of teeth to rotate the second indicator element in a growing amount. In a preferred embodiment, an actuator element is installed in the housing and is responsive to the movement of the container. The actuator element selectively engages at least one of the plurality of teeth of the first indicator element to advance the first indicator element an increasing amount in response to movement of the container relative to said housing. Preferably, a spring is provided in the housing for biasing the actuator towards meshing with the container.

In another aspect of the invention, the indicator assembly, which includes the ratchet wheel, worm screw, actuator element and indicator element of the first embodiment, are installed inside an indicator module which is adapted to be installed inside the housing pump. Similarly, with respect to the second embodiment, the indicator assembly, which includes the plurality of indicator elements, advance member, spring and ratchet element, are supported on the indicator module. The module preferably includes a first and second elements which are joined to form a housing and which support one or more of the ratchet wheels, worm, actuator and indicator element of the first embodiment thereof, or the plurality of indicating elements, advancing element, spring and actuating element of the second embodiment. In the second embodiment, the gear elements are preferably arranged in the module housing. In another aspect of the invention, a key element is installed in the container or housing and is configured to be received in a passage formed in the housing or in the container. In another aspect of the invention, a method is provided for dispensing dosages measured from the container. In one embodiment, the method includes the steps of moving the container along the longitudinal axis to move the valve stem and valve to the open position where the measured dosage is discharged. The longitudinal movement of the container within the housing causes the ratchet apparatus to rotate a predetermined angular amount which in turn, causes the worm to rotate about its axis. Then, the worm engages with the circular worm gear of the indicator element to rotate the worm gear on its axis. Alternatively, in a second embodiment, the first indicator element is rotated a predetermined amount in response to the movement of the valve between a closed and open position, or vice versa. After a predetermined number of movements of the valve, the first indicator element causes the second indicator element to rotate a predetermined amount. In another aspect of the invention, a method for assembling a dispenser comprising a housing, a container and an indicating module is provided. In another aspect of the invention, a package includes components capable of being assembled as a dispensing device for delivering measured dosages of a substance from a container. The package includes a housing, a container having a plurality of measured dosages of the substance and an indicating module having an indicating element. The present invention provides significant advantages over other indicating devices. In particular, with respect to the first embodiment of the indicating device, the worm provides a compact handling component that does not occupy excessive space within the housing. In addition, the worm provides high device reduction ratios, while maintaining a continuous engagement with the circular worm apparatus. The continuous gearing of the worm and the circular apparatus ensures that the accuracy of the counting device is maintained, while simultaneously simplifying the manufacturing and assembly process. The use of a circular apparatus having an axis that is not parallel and preferably transverse or perpendicular to the longitudinal movement of the container within the housing also provides various advantages. It is important to mention that the device can be easily installed in the housing with an economic axis and easy to install. In this way, the circular apparatus provides a compact, single-cycle device that easily fits into the housing and which maintains continuous engagement with the worm apparatus for an improved and accurate adjustment of the indicator element. further, the components are arranged so as not to interfere or otherwise impede the flow of air from the valve stem towards the exhaust port of the housing. In addition, the indicator wheel, which is preferably installed coaxially with the worm apparatus, provides an ideal flat surface for displaying the dosing signals. The user can easily visualize the signals through a viewing window. The second mode of the indicating device provides similar advantages. In particular, the plurality of indicator elements may be installed in a compact arrangement to provide precision and reliability under various operating conditions but which do not impede or obstruct the flow of air to the user. In addition, the different parts are relatively inexpensive to manufacture and assemble. The signals, which are visible to the user through the viewing window, are easy to read and accessible to the user. The indicator module, with any of the different modalities of indicator assemblies arranged therein, also has several advantages. In particular, the independent unit can be manufactured separately and installed as required in any number of conventional types of dispensing devices with minimal modification thereof. In addition, the module can be easily installed without interfering or otherwise preventing the flow of air from the valve stem to the exhaust port and finally to the user. The key element also has several advantages. In particular, passageways and key elements configured in a different manner can be installed between containers carrying different substances such as medicaments and corresponding supply system housings to prevent the user from exchanging several containers and housings and thereby altering the number of doses counted. The key element and way-through can also prevent a user from using the wrong delivery system for a particular container having a particular substance, such as a medicine.

The present invention, together with further objects and advantages, will be better understood by reference to the following detailed description taken in conjunction with the accompanying drawings.

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a perspective view of a dispensing device with a display window that reveals dosage signals. Figure 2 is a perspective view of a mode of the dispensing device with a cutout portion of the housing. Figure 3 is a perspective view of one embodiment of the indicator assembly. Figure 4 is a perspective view of an alternative embodiment of the dispensing device. Figure 5 is a perspective view of the dispensing device shown in Figure 4 with a cut away portion of the housing. Figure 6 is a perspective view of a container, a dispenser housing and an embodiment of a display module with a cutout portion of the housing. Figure 7 is a schematic perspective view of a container, a dispenser housing and an embodiment of the indicator module with a cutout portion of the housing.

Figure 8 is a schematic perspective view of a mode of the indicator module. Figure 9 is a schematic perspective view of the indicator module from the opposite side as shown in Figure 8. Figure 10 is a schematic perspective view of a container and an alternative embodiment of the dispenser housing and the indicator module. Figure 11 is a perspective view of the alternative embodiment of the indicator module shown in Figure 10. Figure 12 is a cross section of a housing and an indicator module installed therein. Figure 13 is a top view of a mode of the indicator module. Figure 14 is a rear view of the indicator module shown in Figure 13. Figure 15 is a cross-sectional view of the indicator module taken along line 15-15 of Figure 13. Figure 16 is a cross-sectional view of the module indicator taken along line 16-16 of figure 13. Figure 17 is a cross-sectional view of the indicator module taken along line 17-17 of figure 13. Figure 18 is a cross-sectional view of the module indicator taken along line 18-18 of Figure 13.

Figure 19 is a perspective view of an alternative embodiment of the module. Figure 20 is a cross-sectional view of the indicator module taken along line 20-20 of Figure 14. Figure 21 is a schematic view of a container, a key element and an indicator module. Figure 22 is a top view of the key element. Figure 23 is a cross-sectional view of the key element taken along line 23-23 of Figure 22. Figure 24 is a perspective view of a container and an alternative embodiment of the indicator module installed in a dispensing housing with a cutout portion of the housing. Figure 25 is a schematic perspective view of an alternative embodiment of an indicator module, key element and indicator assembly. Figure 26 is a top perspective view of a first element of an embodiment of the indicator module housing. Figure 27 is a bottom perspective view of the element shown in Figure 26. Figure 28 is a perspective view of a mode of an indicator element. Fig. 29 is an opposite perspective view of the indicator element shown in Fig. 28.

Figure 30 is a perspective view from above of a second element of an embodiment of the indicator module with an axis installed therein. Figure 31 is a perspective view of an actuator element. Figure 32 is a perspective view of a container with an alternative embodiment of a key element installed thereon placed on a mode of an indicator module. Figure 33 is a perspective view of an alternative embodiment of the key element. Figure 34 is a schematic perspective view of an alternative embodiment of a key element that is applied to a container. Figure 35 is a cross-sectional view of an indicator module showing an advance element of a first indicator element, a gear element and a second indicator element. Figure 36 is a cross-sectional view of the advance element of the first indicator element as it is first engaged by the gear element in the indicator module housing. Figure 37 is a cross-sectional view of the advancing element as it is deflected by the gear element toward gear with the second indicator element for rotating the second indicator element.

Figure 38 is a cross-sectional view of the advancing element as it is released by the gear element and disengages from the second indicator element. Figure 39 is a schematic perspective view of an alternative embodiment of an indicator module and indicator assembly. Figure 40 is an enlarged side view of an actuator element in a disengaged position adjacent to the first indicator element. Figure 41 is a side view of the actuator element engaging the first indicated element with the closure element biased outwards. Figure 42 is a perspective side view of an alternative embodiment of an indicator element. Figure 43 is a side view in opposite perspective of the indicator element of Figure 42. Figure 44 is a cross-sectional view of an advancing element in a first indicator element, a second indicator element and a gear element. Figure 45 is a cross-sectional view of the advancing element as it is first deflected by the gear element. Figure 46 is a cross-sectional view of the advancing element as it is deflected by the gear element toward gear with the indicator element.

Figure 47 is a cross-sectional view of the advancing element as it is further deflected by the gear element towards engagement with the second indicator element. Figure 48 is a perspective view of an alternative embodiment of an indicator assembly disposed on a lower element of the module housing.

DETAILED DESCRIPTION OF THE PREFERRED MODALITIES With reference to the drawings and in particular to figures 1, 4, 6, 7 and 24, there is shown a delivery system, configured as an assortment device or dispenser, which includes a housing 10 or actuator sleeve and a container 100 disposed therein. The housing 10 has a longitudinally extending cavity 12 configured to receive the container. An upper portion of the housing is generally open so that the container can be inserted into the housing through the opening 14 and can be installed therein with a lower end 102 of the container projecting from the housing and is exposed to the user for actuation. . It should be understood that the term "delivery system" as used herein, includes a system or apparatus for delivering a substance from a container, reservoir or similar reservoir, to a user and includes but is not limited to the prescribed dispensing device, which supplies the substance to the user in the form of an aerosol that is inhaled by the user. The term "dispensing device", as used herein, includes devices that extrude, spray or otherwise feed or supply a substance in convenient units and include, but are not limited to, the described inhalation device which supplies measured dosages of a substance in the form of an aerosol for inhalation by the user. The term "longitudinal" as used herein, indicates the direction of reciprocal movement of the container in relation to the housing. The terms "upper", "lower", "up" and "down" are intended to indicate the directions when the inhalation devices are displayed as shown in the figures, but with the understanding that the container is inverted in such a way that the upper surface thereof is located adjacent to the lower part of the housing and vice versa. As shown in Figures 5, 6 and 7, a cylindrical support block 16 having a cavity 18 is formed in a lower portion 22 of the housing. A hole 20 penetrates the support block to communicate with a lower portion of the cavity. A nozzle 24, which has the purpose of being inserted in the mouth of a patient, forms an exhaust port 26 that communicates with the hole and cavity. The nozzle 24 extends laterally from the housing to facilitate insertion of the mouthpiece into the patient's mouth. The container 100 is formed as a cylindrical canister 104 having a hub 106 disposed on an upper surface 108 thereof. A valve stem 110 extends longitudinally from the hub. The valve stem extends coaxially from the can and is deflected outwardly by a spring (not shown) installed inside the can. The container 100 is installed in the housing by pressure adjustment of the valve stem 110 in the cavity 18 of the support block. It should be understood that the container can be configured in a variety of shapes and sizes and that the substance contained therein can be released through a number of valve systems that are known in the art. It should also be understood that the valve system can be operated by a variety of actuators, which include but are not limited to various pumps, levers, actuator covers, buttons and the like. In such embodiments, the valve system can be actuated by a movable actuator relative to the container and housing, so that the container remains fixed relative to the housing. In a preferred embodiment, the container 100 is filled with a substance which is dispensed therefrom in specific metered doses by sinking or moving the valve stem 110 from an extended closed position to a sunken open position, which in turn opens the valve or valve system. Preferably, the substance is a medicine, although it should be understood that the container could be used to carry a variety of non-medicinal substances, including but not limited to different liquids, foams or aerosols that can be supplied by various delivery systems and / or dispensing devices. A medicine is defined as a substance that can be used in therapy, such as for different therapeutic treatments, which include the treatment of diseases (for example, respiratory diseases) and for the relief of pain, and it must be understood that it includes medicines and medicinal substances in general. A simple measured dose is dispensed from the container in each longitudinal and reciprocal movement of the valve stem and simultaneous opening and closing of the valve. Normally, the medication is supplied to the user or patient, through his mouth and / or nose in the form of an aerosol, atomizer or liquid. In operation, the opening of the valve stem and valve is performed by moving the container 100 reciprocally within the housing 10 along a longitudinal axis, defined by the valve stem and the reciprocal movement of the container, by sinking the lower end exposed 102 of the can relative to the housing 10 so as to move the valve stem 110 to the open position as it is supported within the cavity by the support block. Alternatively, an actuator can be moved to open the valve system of the container, which remains fixed with respect to a support housing, an auction and / or an indicator device installed therein. For example, the actuator may be attached to the end of the container in the form of a pump device or the like. Referring to Figures 5-7, while the valve stem is moved to the open position, the container delivers a measured dose of the aerosolized substance through the cavity 18 and orifice 20 and into the exhaust port. The aerosolized substance is then transmitted to the user through the exhaust port of the nozzle either by means of a generated or assisted air flow. Alternatively, the measured doses of liquids and the like can be dispensed from the container. In other delivery systems, which may also include a dispensing device, the housing and fastener of the container are attached to a component having a chamber with an outlet end. Examples of these types of delivery systems and dispensing devices are shown for example in the U.S. patent. 5,012,803, issued May 7, 1991, and patent of E.U.A. 4,460,412, issued September 11, 1984, the complete descriptions of which are incorporated herein by reference. (It is not intended to grant a license, express or implied, to any of these patents by virtue of incorporation by reference herein). In these types of delivery systems, the component having the chamber can be adapted to receive the mouthpiece of the housing, or it can be integrally connected with a holder supporting the container. In any embodiment, the measured dose of substance, preferably an aerosol medication, is first taken from the container into the chamber and subsequently inhaled by the user. In a preferred embodiment, the container 100 is intended to supply a predetermined number of measured doses of substance. For example, conventional containers for inhalation typically carry about 100 to 200 metered doses. In operation, it is important that the user is aware of the number of measured doses remaining in the container so that the user is not surprised with an empty bottle when he needs the substance, such as a medication. Referring now to Figures 2 and 3, there is shown a dispensing device, configured as an aerosol dispenser, including a housing, a container installed therein as described above and an indicator assembly. The indicator assembly includes a ratchet apparatus 32 installed coaxially with an auger 40 on an axis 42 in a lower housing position. A plurality of teeth 34 is formed around the periphery of the ratchet apparatus. The teeth 34 are cut or formed with a tapered surface 36 and a gear surface 38. In a preferred embodiment, the ratchet and worm are formed of a durable compact plastic. It should be understood, however, that other materials such as metal may also work. The ratchet and worm can be made as separate parts or molded as a single integral element. In a preferred embodiment, the shaft 42 and worm 40 define an axis of rotation transverse or perpendicular to the longitudinal axis defined by the valve stem and reciprocal movement of the container relative to the housing. The opposite ends of the shaft 42 are rotatably supported in the housing.

Furthermore, as shown in FIGS. 2 and 3, an indicator element 50 comprises a circular worm apparatus 52 and an indicator wheel 58 coaxially installed on an axis. In a preferred embodiment, the axis 56 defines an axis of rotation transverse to the axis defined by the worm and also transverse the longitudinal axis defined by the reciprocal movement of the container relative to the housing. The shaft 56 is rotatably supported in the housing. The teeth 54 are formed around the periphery of the worm apparatus 52 and are configured to engage permanently with the worm 40. As shown in Fig. 2, the indicator wheel 58 has a flat face 60 which it is exposed to the patient through a viewing window 28 formed in the housing. The ratchet apparatus 32, worm 40, worm apparatus 52 and indicator wheel 58 provide an ideal arrangement for indicating the number of doses remaining in the container or the number thereof. In particular, relatively high reduction ratios are possible through the use of the ratchet, end screw and worm apparatus without the corresponding requirement to provide extremely fine teeth in one or more of the ratchet or screw apparatus without end. In addition, the interface of the worm and worm apparatus avoids the associated deficiencies introduced by the engagement and potential bounce of conventional straight gears having fine teeth. In addition, the installation of the indicator element is carried out by installing a simple axis which can be supported in a plurality of angular positions and orientations within the housing. It is important to mention that the high reduction ratio realized with the worm 40 allows the worm apparatus 52 to have a relatively small diameter, so that it can be easily installed within small spaces within the housing. In fact, as shown in Figures 6 and 12, the complete indicator assembly can be installed behind the support block 16 and below the upper surface 17 thereof, so that the assembly does not interfere with the medicament assortment from the orifice or with the air flow generated by the patient when administering the medication. With reference to Figure 5, an actuating element 70 is configured as a post element 72 movably supported in the housing along an axis parallel to the longitudinal axis defined by the reciprocal movement of the container within the housing. In an alternative embodiment shown in Figures 7-9, the post element includes an upper portion 74, a middle portion 76 and a lower portion 78. A flexible arm member 80 extends from the middle portion of the post element and terminates in a tapered hook member 82 configured to selectively engage one of the ratchet wheel teeth. The middle portion 76 is defined by upper and lower stop surface 84, 86. A spring 88 is disposed near the lower portion 78 of the post element and meshes with the lower stop surface 86 to bias the drive member up against the upper surface 108 of the can as shown in figure 7. Although a compression spring is shown in the figures, it should be understood that the bracket, tension spring, torsion spring and leaf springs and the like could also function to deflect the actuator upwards to engage with the container. The springs can be made of metal or plastic. In an alternative embodiment, shown in Figures 2 and 3, the actuator member 90 includes a clamping ring 92 and a flexible arm member 94 extending longitudinally downward therefrom. A longitudinal groove 96 is formed in the fastening ring to allow the fastening ring 92 to extend and arrange around the hub 106 (shown in Figure 5) of the can in a close fit configuration so that the valve rod of the container extends through the opening 98 of the fixing ring. A distal end of the flexible arm element terminates in a hook element 95, which is configured to selectively engage the teeth of the ratchet wheel. In the operation of the embodiment shown in Figures 6-9, 13-18 and 20, the container moves longitudinally within the housing to sink the valve stem to the open position so as to open the valve as explained above. While the container moves downwardly within the housing, the actuator member 70 moves longitudinally downwardly so that the hook member 82 meshes with the ratchet wheel and rotates a predetermined angular amount corresponding to the advancement of the teeth. When the user releases the container, the spring (not shown) within the container deflects the container upwardly into the housing along the longitudinal axis so that the valve stem 110 moves to the closed position within the container to close the container. valve. As the container moves upward, the flexible arm member 80 deviates laterally outwardly while a tapered end portion of the hook member 82 slides against the tapered surface 36 of one of the ratchet teeth. As the container and the flexible arm element reach the top of the stroke, where the valve rod moves completely towards the closed position, the flexible arm member 80 returns to its normal straight configuration according to the hook element 82. it slides past the tapered surface of one of the teeth to be placed on the gear surface 38 of that tooth 34 for the next cycle. Alternatively, the operation of the ratchet wheel can be reversed as shown in FIG. 3. In this embodiment, the flexible arm member 94 is biased outwardly by the tapered surface of one of the teeth of the ratchet apparatus in FIG. the descending race. In the lower part of the stroke, the hook element 95 slides towards an underlying relationship with the gear engagement surface of the tooth. When the user releases the container, the spring (not shown) inside the canister diverts the container upwardly into the housing along the longitudinal axis so that the valve rod moves towards the closed position within the container. As the container moves upward with respect to the housing, the flexible arm member 94 moves longitudinally upwardly so that the hook member 95 meshes with the gear surface 38 of one of the teeth and thus rotates the wheel ratchet a growing amount. In the embodiment shown in Figures 6-9, 13-18 and 20, it is the force of the spring 88 that moves the arm member 80 upwards to return the actuator element for the preparation of another cycle. In the alternative embodiment shown in Figures 2 and 3, it is the movement of the container, as it is deflected upwards by the internal spring acting on the valve stem, which causes the fixing ring 92 and the arm element 94 move upwards and in this way rotate the ratchet apparatus. Referring to Figures 8 and 17, a flexible closure element 200 engages the ratchet apparatus adjacent the hook element to ensure that the rotation of the ratchet apparatus is unidirectional. Alternatively, the closure element can be positioned to engage the ratchet apparatus opposite the actuator arm element. The closure element includes an end portion adapted to engage with the engaging surface of the teeth of the ratchet apparatus. As the ratchet apparatus rotates through the actuator, the closure member slides along the tapered surface of one of the teeth of the ratchet wheel and does not interfere with the rotation thereof.

The rotation of the ratchet apparatus causes the worm 40 to rotate by a predetermined amount desired. It should be understood that the desired amount of rotation depends on the diameter of the ratchet wheel and the number of teeth placed thereon. The rotation of the worm, which meshes permanently with the teeth of the worm apparatus, causes the worm apparatus and the indicator wheel to rotate a predetermined increasing amount. The amount of rotation of the indicator wheel depends on the advance of the worm, the number of worm threads and the advance of the worm apparatus and the number of teeth of the worm apparatus. In a preferred embodiment, the worm has a simple thread. For ease of manufacturing, it is advisable to provide as ordinary an advance as possible in each of the ratchet and worm devices, although the apparatuses are still defined as fine tooth apparatuses. However, it is also intended that the indicator element only make one simple revolution (single cycle) corresponding to a complete evacuation of medication from the container. In this way, when a large number of doses (in the order of 200 or more) is contained within the can, it is important for the ratchet, worm gear and worm gear to provide a relatively high reduction ratio of so that the 200 linear reciprocal movements of the actuator element correspond to one or less revolutions of the indicating element. Because the ratchet and worm apparatus rotate together, it should be understood that the number of teeth in the ratchet and worm apparatus, and the number of worm threads, determine the last reduction ratio between the rotation of the ratchet apparatus and the rotation of the indicator wheel. For example, when the container carries 240 metered doses, an acceptable ratio is made if the pawl is made relatively ordinary with 10 teeth and the worm apparatus is provided with 28 teeth. In operation, the assortment of 10 measured doses will cause the worm to make a complete revolution in order to move a tooth of the worm apparatus. After 240 reciprocal linear movements, the worm has advanced 24 teeth. Additional teeth are provided so that the start and end signals, which indicate a relative filling or emptying of the container respectively, are not marked one above the other. In a preferred embodiment, shown in Figures 9 and 15, the worm apparatus 52 has teeth formed only about a portion of its periphery so that a gap between the teeth is formed around the remaining portion of the periphery. In operation, the apparatuses are configured so that the worm 40 disengages from the last tooth of the worm apparatus as the final prescribed dose of medicament is dispensed. In this position, the signals on the indicator wheel 58 will indicate to the user that the boat is empty. Therefore, although the user may continue to move the container to open the valve, the resultant movement of the actuator 70, ratchet apparatus 32 and worm screw will not in turn turn the indicating element according to the space in the teeth in the apparatus. Endless screw result in the disengagement of the worm and worm gear. In this way, the indicator wheel is prevented from being turned inadvertently from a filling reading to a vacuum and then returning to a filling reading, which would confuse the user on the number of doses remaining in the bottle. The indicator wheel 58, signals 66 and display window 28 can be arranged in configuration mode for the user to visualize them. For example, the viewing window 28, 124 may be configured as a window of rectangular shape as shown in Figure 2 or 10 respectively, as an arched window 29 as shown in Figure 4, wherein approximately 1/3 of the face of the indicator wheel it is visible at any time, as a circular window (not shown) or as any other form that allows the user to visualize the indicator wheel and the signals located in it. In one embodiment, the signals take the form of a red code where, for example, a portion of the wheel is green to indicate the start filling position, a portion is yellow to indicate a medium fill and a portion is red to indicate that the container is empty. Obviously, other colors, shading or alphanumeric signals can be provided on the indicator wheel to indicate the relative filling or emptying of the container.

In an alternative embodiment, the indicator wheel may be oriented within the housing so that either its flat face or its circumferential surface, with signals applied thereto, are visible to the user through the exhaust port of the nozzle. Referring to Figure 25, an alternative embodiment of an indicator assembly is shown. The indicator assembly includes three indicator elements 550 coaxially installed on an axis 556 and rotating around it. As best shown in Figures 28 and 29, each indicator element includes an indicator wheel 558 having a circumferential skirt 559 with an outer circumferential surface 560 on which the signals (shown in numbers) are applied and a ratchet 552 apparatus coaxially installed with the indicator wheel. The indicator wheel and ratchet apparatus have an opening 553 configured to receive the shaft. Ratchet apparatus 552 includes a plurality of teeth 554 formed around its periphery. Preferably, the ratchet apparatus is integrally molded with the indicator wheel, although it should be understood that the apparatus and the wheel may be made separately and therefore adjoined to one another by welding, adhesives and the like. In one embodiment of the indicator element, a flexible advancing element 600 is formed from a portion of the circumferential skirt 559 by providing a prolonged circuit breaker 602 on the indicator wheel radially inward from and below the skirt. The advance element 600 includes a laterally extending tooth portion 604 having a gear surface 606. The three indicator elements are coaxially installed so that the tooth portion 604 of the advance element of a first indicator element rests on the teeth of the ratchet apparatus 554 of the second indicator element, and so that the portion of teeth 604 of the advancing element of the second indicator element rests on the teeth of the ratchet apparatus 554 of the third indicator element. When only three indicator elements are used (as shown in figure 25), the third indicator element does not require an advance element, although considering the simplicity of manufacture, it is preferable to use a modular indicator element with the same signals applied to it and the same advance element formed therein for each first, second and third indicator element. It should be understood to the person skilled in the art that one or more indicator elements may be used to provide an indication of used or available dosages and that the three indicator elements shown in the figures are intended to be illustrative rather than limiting. Furthermore, it should be understood that a plurality of indicator elements refers to any number of indicator elements greater than one. In an alternative embodiment of indicator element 650, shown in FIGS. 39, 42 and 43, a feed member 800 is disposed radially inward from a circumferential skirt 659 and includes a first end 657 connected to a flat side portion or cube 655 of the indicator wheel. The advancing member includes a curved flexible portion 708 having a free end with a portion of teeth 704 extending laterally outwardly therefrom so as to extend laterally from below the skirt 659 of the indicator wheel, so that it rests on the teeth of the wheel. ratchet apparatus of an adjacent indicator element coaxially installed thereon as shown in Figure 48. The signals, preferably in the form of numbers, are applied to the circumferential surface 660 of the skirt. A ratchet apparatus 652, having a plurality of teeth 654 is coaxially installed with the indicator wheel. As shown in Figure 48, three indicator elements are coaxially installed on the axis 656. Referring to Figures 25 and 39, an actuating element 570, 670, otherwise referred to as a ratchet element, shows that it has an upper portion 574, 674 extending upwardly from a lower portion 578, 678 and a flexible arm member 580, 680 that is extends outwardly therefrom and ends in a flexible hook member 582, 682 configured to selectively engage at least one of the teeth of the ratchet apparatus of the first indicator element. A spring 588, 688 is disposed about the lower portion of the actuator member and biases the upper portion 574, 674 of the actuator member toward engagement with the container. Referring to Figure 27, a housing 820 is shown having a pair of gear elements 770 integrally formed with the housing and including inclined surfaces 772. A plurality of closure members 900 extends from the housing and meshes selectively with the ratchet apparatus to ensure unidirectional rotation of the indicator element as shown in Figures 35-38. Although gear elements and closure elements are shown to be formed or extending from a module housing, as described below, one skilled in the art should understand that those elements or equivalent features can also be formed in or be related to the dispenser housing or actuator sleeve supporting the container or being arranged or connected to the container itself. Referring to Figures 25 and 35-38, the operation of the indicator assembly shown in Figure 25 is generally shown. In particular, the container moves longitudinally within the housing 10 to sink the valve stem 110 to the position open to open the valve as explained above. As the container moves down into the housing or down relative to the housing of the module described below, the actuator member 570 moves longitudinally downward so that the hook member 582 is biased outwardly by the ratchet apparatus 552 on a first external indicator element. In the lower part of the stroke, the hook element 582 is inserted into an underlying relationship with the teeth in the ratchet apparatus. When the user releases the container, the spring (not shown) within the container deflects the container upwardly into the housing along the longitudinal axis, so that the valve stem 110 and the valve move to the closed position within the container. container. As the container moves upward, the flexible arm member 580 moves longitudinally upwardly so that the hook member 582 rotates the first indicator element a predetermined increasing or angular amount corresponding to the advance of the teeth disposed around the periphery of the ratchet device. As the container and the flexible arm element reach the top of the stroke, where the valve stem and the valve move completely to the closed position, the flexible arm member 580 is placed on the ratchet apparatus for the next cycle. Alternatively, the operation of the actuator element and ratchet apparatus can be reversed, as explained above with respect to the mode shown in Figures 6-9. Referring to Figures 39-41 and 44-48, a plurality of flexible arm elements 700 is shown extending from a module housing to be aligned with the ratchet devices in each of the indicator elements. The arm elements 700 each serve as a combined gear element and closure element. In particular, as shown in Figures 40 and 41, the arm member 700 functions as a closure element and includes an end portion that deviates from the teeth in the appliance. ratchet as the drive element or adjacent indicator element is driven with its advancing element to advance the ratchet apparatus. The operation of the actuating element 670 and ratchet apparatus is similar to the operation of the ratchet apparatus shown in Figures 6-9 as explained above. The arm member 700 is rapidly reset so that the end portion meshes with one of the teeth of the ratchet apparatus to ensure that the rotation of the ratchet apparatus is unidirectional. As shown in figures 44-47, the arm element 700 resting on the ratchet devices of the second and third indicator element, also serves as a gear element that selectively meshes the advance elements connected to the indicator elements. In operation, the reciprocal movement of the container relative to the housing is repeated until the first indicator element 550, 560 and its ratchet apparatus are rotated one full revolution. The predetermined number of reciprocal movements required to advance the first indicator element one revolution is equal to the number of teeth disposed around the periphery of the ratchet apparatus 552, 652. As the first indicator element rotates by successive movements of the container relative to the housing , the advancing element 600, 800 of the first indicator element is brought into selective engagement with the gear element, configured as the inclined surface 772 formed in the housing or as the upwardly extending arm element 700. In particular, the gear element 700, 772 deflects the tooth portion 604, 704 of the advancing member in engagement with one of the teeth 554, 654 of the ratchet apparatus in the second indicator element.

As the first indicating element of the container rotates with successive movements relative to the housing, whether this is the dispensing housing for the housing or the module housing described below, the advancing element 600 meshes with one of the teeth on the ratchet wheel of the adjacent indicator element and the indicator element advances a predetermined and increasing angular amount corresponding to the advance of the teeth of the ratchet apparatus. The increasing term refers to the angular amount in which the indicator element is moved by the advance of a drive, which corresponds to the movement of a tooth, without considering whether the indicating device is indicating the number of remaining doses (for example, counting). descending) or if you are indicating the number of doses administered (for example, ascending count). According to the flexible advancing element 600, 800 clears the gear element 772, 700, it jumps away from the ratchet apparatus so that subsequent advances of the first indicator element do not effect a rotation of the second indicator element until the first complete indicator element Another cycle for putting the advancing element back into gear with the next tooth of the ratchet apparatus of the second indicator element and so on. The second indicator element 550, 650 with its advance element 600, 800, interacts in a similar manner with a second gear element resting on the teeth of the third indicator element to selectively engage and advance the third indicator element a predetermined increasing amount. for each complete rotation of the second indicator element. It should be understood that more indicating elements can be assembled in a similar manner to provide an increasing indicating device. In a preferred embodiment of the dispensing device, shown in Figures 6-10, 13-18, 20, 24, 25 and 39, the indicator assembly is disposed on a display module 120, 1020, 1120. The indicator module 120, 1020 , 1120 is configured to be received within the housing where it is disposed about a portion of the support block 16. In particular, the support block is spaced away from the wall of the dispenser housing, referred to otherwise as the actuator cover , to form a receptacle in the shape of a donut in the lower part of the housing. The module includes a module housing 130, 1030, 1130 having an internal concave surface 132, 1032, 1132 which is configured to coincide with an external convex surface of the cylindrical support block and an external convex surface 134, 1034, 1134 which is configured to coincide with the internal concave surface of the housing which is also generally cylindrical. In this way, the module housing is configured to be received within the receptacle formed around the support block. Preferably, the module housing has a semicircular shape and fits around a portion of the support block opposite the orifice opening so as not to interfere with the medicament assortment, or with the air flow that the medicament transmits to the patient. In this way, the module is held back from the midpoint of the support block. The person skilled in the art should understand, however, that the module or module housing can be configured in any number of different sizes and shapes to be accommodated in a variety of housings or hull assemblies, with or without support blocks and the like. . As shown in Figures 8-9, one embodiment of the module preferably includes a front portion 210 extending from the rear convex surface of the module and includes a module 64 viewing window. The front portion is inserted into the opening of the housing display window (circular opening not shown) to secure the module therein. As shown in an alternative embodiment in Figures 10-12, the front portion includes a vertically oriented rectangular viewing window 68 and a downwardly extending fastening element 122 which extends through a spout display window opening 124 and meshes with a lower wall of the housing. In other embodiments, shown for example in Figures 24 and 30, the front portion 1031, 1131 and display window 1064, 1164 have a prolonged horizontal orientation to provide the user with a display of the plurality of indicator elements installed within the module. However, it should be understood that the module can be secured within the housing by any number of conventional means, including the use of closures or adhesives. Alternatively, the module can simply be adjusted by pressure in the receptacle formed between the support block and housing wall.

In the embodiment shown in Figure 8, the circular display window 64 is provided in the module housing to expose a substantial portion of the flat indicator wheel. On the face 60 of the indicator wheel, numerical signals are provided, corresponding to the number of doses in the container. An arrow, or similar indicator, is applied to the housing adjacent to the display window and provides a signal of the number of doses remaining in the housing or the number dispensed therefrom, as the indicator wheel rotates. In other alternative embodiments, shown for example in Figures 10, 11, 25 and 39, the signals are applied to a circumferential surface 62, 560, 660 of the indicator wheel. The display window of the module 68, 1064, 1164, which is preferably rectangular and the indicator wheel are arranged so that the circumference or periphery of the wheel or wheels, is visible through the display windows of the dispenser and module . As with the other embodiments, the signals may take the form of color coding, shading, alphanumeric characters and the like. In the embodiments shown in Figures 28-29 and 42-43, the signals are preferably formed around the circumferential surface 560, 660 of the indicator wheel in the form of numbers ranging from 0 to 9, with the ratchet the indicator element that has 10 teeth. In operation, it should be understood that the three indicating elements, more or less, can be preset to a maximum number of dosages contained within the container, with the signals or in this case numbers, arranged around the periphery of the indicator wheel, of so that the successive and sequential actions of the container cause the indicator elements to count downwards. Alternatively, the indicator elements are assembled so that the zero (0) of each indicator element is displayed in the display window for the user. The container is then operated by the user so that the first indicator element rotates inside the housing to display in sequence the number of doses that have been supplied from 1 to 9. After the tenth actuation, the indicating element completes a simple revolution, in virtue of the ten teeth preferably formed around the ratchet apparatus which corresponds to the predetermined number of drives, and causes the second indicator element to advance a number from 0 to 1 as the first indicator element again displays a 0 so that both Elements indicate jointly that 10 dosages have been supplied. The first indicator element is again rotated by successive operations until another simple rotation is completed to subsequently rotate the second indicator to reveal the 2, in order to indicate that 20 dosages have been supplied. After a complete rotation of the second indicator element, corresponding to 100 drives, the third indicator element advances to reveal a 1 in the display window with the first and second indicating elements revealing a 0, and so on.

As shown in Figures 6-10, 13-18 and 20, one embodiment of the indicator assembly, which includes the worm screw, worm gear, ratchet apparatus and indicator element, is installed within the module housing 130. Similarly, the embodiments of the indicator assembly shown in FIGS. 25 and 39 are preferably supported in a module housing 1030, 1130. Preferably, the module housing is formed from a first and second driver element. cover 136, 138, 1036, 1038, 1136, 1138 although it should be understood that a piece of integral and simple material would also work, such as any plurality of joined elements. Referring to Figures 6-10, 30 and 39, the first cover element 136, 1136, 1036 has a vertical wall 140, 1140, 1040 defining at least a portion of the external convex surface 134, 1034, 1134 configured to coincide with the internal surface of the housing as described above. The second display window 64, 1064, 1164 of the module is provided on the vertical wall 140, 1040, 1140 to be aligned with the housing display window when the module is installed therein. The viewing window is framed by the face portion. In one embodiment, illustrated in Figure 9, the first element also includes a pair of opposing support points or supports 144 formed on the inner surface of the vertical wall. The points of support 144 are configured to support the ends of the shaft 42. Alternatively, as illustrated in Figures 27 and 30, a fulcrum or clamping leg may be placed on each of the first and second covers. As can be seen in figures 9 and 30, a post 146, 1046 extends upwards from the base 150, 1050 of the first element adjacent to one of the support points and this post has a receptacle or socket 148, 1048 formed in coaxial form on it. Alternatively, as illustrated in FIG. 39, the base 1150 is formed as part of the second cover and includes an opening 1148 configured to receive the lower portion 678 of the actuator element. With reference to Figures 8 and 9, the second cover 138, 1038, 1138 engages the first cover 36, 1036, 1136 to form a closed enclosure therebetween. The second cover includes a vertical wall 152, 1052, 1152, and a portion of this wall defines the concave surface 132, 1032, 1132 configured to engage with the outer surface of the support cradle. An upper horizontal flange 154, 1054, 1154 extends from the vertical wall 152, 1052, 1152 and engages the vertical wall of the second cover in a superjacent manner, so as to close the upper part of the module. In an alternative embodiment, the top flange 1154 is formed as part of the first cover. The top flange 154, 1054, 1154 has an opening 156, 1056, 1156 formed thereon and configured to receive an upper portion 74, 574, 674 of the post. In one embodiment, the top surface of the rim is flush with or below the top surface of the support cradle, so as not to interfere with the reservoir when it is depressed towards the support cradle. Alternatively, as illustrated in FIGS. 8 and 9, the modular housing has a semicircular cavity 155 configured to receive the central portion while the reservoir is actuated, whereby the reservoir surface 108 engages with the upper portion of the reservoir. actuator element and surface 108 is located adjacent the surface 154 of the modular housing when the valve is placed in the open position. A lower edge 158 of the vertical wall engages the base 150 of the first cover to close the bottom of the module. As illustrated in FIGS. 8 and 9, 25 to 27, and 30, the covers are joined by vertical flanges slidingly engaged 160, 1060 on the first cover, with slots 162, 1062 formed on the second cover. Inwardly extending tabs 220, 1061 are press fit by quick positioning in slots 222, 1063 formed in the second cover. In the embodiment illustrated in FIGS. 26, 27 and 30, a tab 1067 engages with the opening 1071 formed in a wall 1069 which contributes to defining a portion of the concave outer surface of the modular housing. Alternatively, it should be noted that the first and second covers can also be joined by fastening devices, adhesives and the like. As can be seen in figures 7, 15, 32 and 48, the covers are assembled to form the modular housing, and the upper portion 74, 574, 674 of the post extends through the opening in the upper flange of the first cover and engages with the upper surface 108 of the reservoir, which is inverted within the housing. Alternatively, the actuator element can be fixed to the central part of the reservoir with the key ring, as described above. In this embodiment, the drive lever of the actuator member extends downwardly from the ring through the opening in the upper portion of the first cover and is positioned to selectively engage with the retainer. The insertion of the driving lever into the opening prevents the container and the key ring from rotating, thus preventing the driving lever from being released from its selective engagement position with the holding device. As can be seen in Figures 9 and 25, the lower portion 78, 578 of the post can be movably accommodated within the receptacle, 148, 1048 formed in the post 146, 1040 extending from the base of the second cover. Alternatively, the lower portion 678 is housed in the opening 1148 as illustrated in Figure 39. With reference to Figures 9, 25 and 39, the spring 88, 588, 688 is disposed about the lower portion 78, 578, 678 , and in some embodiments includes a lower end mounted on the post 146, 1046. The upper end of the spring engages the lower stop or stop surface 86, 586, 685 of the post 72, 572, 672. The spring drives the post upwardly within the housing such that the upper portion 74, 574, 674 protrudes through the opening and engages with the upper surface of the reservoir 108. In another embodiment, illustrated in FIGS. 8 and 9, the worm 40 and the holding device 32 are supported on the support points 144 formed on the second cover, so that they can rotate.

Preferably, the opposite ends of the shaft 42 are snapped into the support points. The indicator element 50 is supported so that it can rotate about the second cover in such a way that the worm gear engages with the worm when the covers are joined together. In particular, the second cover includes a pair of clamping legs 164, 166 that open downwards. The shaft 56 of the indicator element is housed in the first clamping leg 164 and the central part 59 located between the worm gear and the indicator wheel is housed within the second clamping leg 166. Preferably, the axis and the central part they snap on the clamping legs, but can freely rotate inside them. When the covers come together, the indicator element, and in particular the worm gear, are caught between the clamping legs and the worm. In an alternative embodiment illustrated in Figures 25 to 27 and 30, the shaft 556 is supported at its opposite ends by the portion 1044 of the gripper leg extending from each of the upper and lower covers 1036, 1038. The axle 556 has a T-shaped cross-section, shaped by molding, for example, when the shaft is integrally formed or molded with one or more of the covers of the modular housing. The shape of the shaft also makes it possible to function as a key when it is housed in receptacles of a similar shape configured in one or more of the clamping legs. The shaft extends outwardly from the portion of the clamping leg. The shaft includes opposite curved surfaces 555, 557, as can be seen in figures 35 to 38, which provides a bearing surface for the indicator elements mounted thereon so that they can rotate. The person skilled in the art will appreciate that the shaft can have a circular cross section and can be mounted on the housing so that it can rotate. In this embodiment, at least one of the indicator elements can be integrally formed together with the axis, or all the elements can be mounted independently on it. It should be noted that in the alternative embodiment of Figures 2 to 5, the structure supporting the worm and the ratchet wheel, including the support points or similar supports, and the support structure of the indicator element, including the clamping legs , are similar to the structure provided in the modular housing, but are integrally molded into the interior of the housing. Similarly, a post and a receptacle can be integrally molded to the bottom of the dispenser housing in order to support the actuator element and the spring. Similarly, although the embodiments of the indicator assembly of Figures 25 and 39 are illustrated as being preferably mounted on the indicator module, those skilled in the art will appreciate that the assembly, including the shaft, the indicating elements, the driving element and the spring may be directly mounted in the spout housing or in the housing of the actuator supporting the reservoir. Similarly, the coupling element (s) and the anti-return element (s) may be formed in the dispensing housing supporting the reservoir, also referred to as the actuator housing. In an alternative embodiment illustrated in FIG. 19, a lower portion 172 of the external vertical wall of the modular housing is angled so that it can be engaged with a housing having a flat bottom with a similarly angled surface. As illustrated in Figure 19, the axis of rotation of the indicator element is oriented at an angle of approximately 45 degrees with respect to the longitudinal axis, such that the face of the indicator wheel 60 is substantially in parallel with the angled surface of the indicator wheel. accommodation. The angled surface 172 has a viewing window that is aligned with a similar viewing window provided in the angled wall of the dispensing housing. With reference to figures 21 to 23, the key 300 includes a base portion 302 with a cavity 304 configured to receive the upper part of the reservoir. The base portion has a circular shape and is open in the center. The key is mounted to the reservoir when a circumferential flange 306, which forms a cavity, is placed around the reservoir so that the valve rod and the central part pass through an opening 308 formed in the center of the container. the key. Alternatively, the key can be mounted in the tank by means of an adhesive or other fixing device. This key includes a key portion 310 that extends downwardly from the base portion. The key portion is preferably configured as a circular flange, although it is possible to use other configurations. In alternative embodiments illustrated in Figures 25, 32 and 33, the key 1300 includes a frame portion 1302, configured as a collar or ring with a variety of serrated portions 1304. The mount 1302 is configured to fit the end of the reservoir in such a manner. so that the grooves hold a part of the deposit. A variety of pull levers 1306 hold the key portion 1308 to the mount. In another alternative embodiment illustrated in Figure 34, the mount 1402 has a diameter smaller than that of the key portion, and is arranged coaxial with respect to this portion of the key. A base member 1404 connects the frame to the key portion. The frame includes a variety of inwardly facing tabs 1410 that engage a tapered or conical outer surface of the central portion 106 of the reservoir. In the embodiments illustrated in Figures 25 and 34, the key portion 1308, 1408 is configured as a circular rim with a variety of openings 1312, 1412 formed thereon around its circumference in order to allow air to flow through the key with less restriction. In the embodiment illustrated in FIGS. 32 and 33, the key portion 1508 includes two coaxially mounted key portions of different diameters, each with a variety of openings 1512 to allow air flow therethrough.

The embodiment of the indicator module illustrated in Figure 21 has a keyhole configured as a cavity 312 formed in an upper surface of the modular housing. Preferably, in this embodiment the cavity is configured as a groove of curved or semicircular shape. The actuator element 314 extends upwardly from the modular housing into the slot. The actuating element 314 is located flush with, or below, the upper surface of the module 316. In this way, the actuator can not be activated by the user's finger in such a way as to inadvertently advance the indicator element and therefore This provides an incorrect or inaccurate reading of the amount of remaining doses in the reservoir, or of the amount of doses administered by it. The shape and diameter of the portion of the key and of the corresponding keyhole are configured in such a way that the portion of the key communicates with and is housed in the keyhole formed in the modular housing. When the reservoir is mounted in the spout housing so that the valve stem is housed in the source of the support cradle, the key portion is housed in the keyhole and engages with the actuator element. In an alternative embodiment of the dispensing device or spout, with or without the indicating module or the indicator assembly, a keyhole can be configured directly on the spout housing, for example, in a lower portion of the spout housing, where it accommodates a portion of the spout housing. key arranged in the deposit. It should be noted that the term "accommodation", as used herein, refers to either the dispenser housing, the modular indicator housing, or a combination of both accommodations. In another alternative mode, the key portion and the keyhole are inverted. In this embodiment, the portion of the key is formed on the housing, that is, the modular indicator housing, or the dispenser housing if the dosing device does not have a display module and / or indicator assembly, and the keyhole is formed in The deposit. For example, the modular housing, or the dispenser housing, may include a ring that is housed in an annular-shaped cavity in the central portion of the container. Or, the dispenser housing or the modular housing can be configured to include one or more protuberances that are housed in one or more cavities formed in the reservoir. In this way, keys with configurations of their different key portions can be applied to deposits containing different types of substances, such as a medicine, in order to prevent the user from confusing the deposits and dispensers. In operation, a reservoir that has a specific key with a specific key portion can only be installed in a dispensing housing with a keyhole configured to accommodate that specific key portion. If the portion of the key does not correspond to the cavity, the key ring will be coupled to the upper surface of the modular housing in such a way that it will prevent activation of the reservoir relative to the dispenser housing and the subsequent opening of the valve. This in turn prevents the user from installing deposits with different substances in different jets, since this could adversely affect the counting of the doses administered from the deposit, or the counting of the quantity of doses remaining in the same. For example, a key with a key portion with a thickness of 1 mm and an internal diameter of 13 mm can not be installed in a keyhole with a width of 1 mm and an internal diameter of 15 mm, and vice versa. It should be noted that the corresponding key and keyhole can also be used together with various dispensing or dispensing systems that do not include an indicating device, as explained above. Frequently, dispensing systems can be configured to administer a specific type of substance. It is possible that a dispensing system configured in a different way does not take full advantage of the supply of the substances that it is planned to administer, such as a drug, so it may be important to ensure that a specific dispensing system is used for a particular substance. In this way, it is possible to mount a corresponding key and keyhole in the tank or in the housing, or in a similar structure, of the dispensing system, in order to ensure that the appropriate deposit is placed on the relevant dispensing system. In the alternative embodiment of Figure 25, the modular housing includes three pairs of vertical members, 1080, 1082 that form a slot or cavity 1084 between each pair. Likewise, the vertical elements of a pair 1082 are configured as channels that open towards each other. The elongated cavity 1056 formed between the pair of elements is configured to receive the upper portion of the actuator element 574. In operation, the portion of the key 1308 is configured to penetrate the various slots or cavities, or keyholes, to engage with the element. actuator arranged in the elongated cavity. When the reservoir is moved with respect to the modular housing in such a way as to place the valve in its open position, the central part of the reservoir is housed in a cavity formed between the internal vertical element of each pair. In the embodiment illustrated in FIGS. 32 and 33, three groups of three vertical elements 1180, 1182 are provided, and each group of three has two slots 1184 formed between the elements for housing the two key portions 1508 of the key 1500. Again, a group of three elements 1182 forms an elongated keyhole, or cavity 1056, configured to house the actuator element. The configuration of two key portions allows multiple combinations of shapes and diameters of key portions to provide a different key combination for each of the substances supplied from the various reservoirs. Although circular configurations of the key portion and corresponding slots configured to receive such key portions are preferred, as illustrated in the figures, they allow the tank to rotate inside the spout housing about its longitudinal axis It should be noted that the portion of the key and the slot, or the keyhole or similar hole, can have any type of corresponding configuration and that the corresponding shapes are not limited to a circular configuration as illustrated in the figures. The indicator module provides an economic and accurate device for counting the doses of drugs and the like. The module can be configured to be easily installed as a separate unit in most conventional inhalation housings, with minimal modifications to the housing, including a viewing window in the housing aligned with the module display window and the elimination of any structure formed between the support cradle and the outer wall of the housing. Also, the module can be installed behind the support cradle, in such a way that it does not interfere with or otherwise impede the necessary air flow in order to administer the medication. Although the present invention has been described with reference to the preferred embodiments, those skilled in the art will appreciate that it is possible to make changes in the forms and details without departing from the scope and intent of the invention. Accordingly, the foregoing detailed description will be construed as illustrative but not limiting and the appended claims, including all their equivalents, will be those that define the scope of this invention.

Claims

NOVELTY OF THE INVENTION CLAIMS 1. - An indicating device that indicates the amount of doses regulated with dosimeter or meter of a drug administered from, or what remains of that medication in, a reservoir located inside a dispensing housing that has a cavity, and this reservoir has a valve movable between a closed position and an open position, and the reservoir supplies a regulated dose with a counter when the valve is moved to its open position, and the aforementioned indicating device includes: an indicating module, which in turn includes: a modular housing configured in such a way that it can be housed within the cavity of the dispenser housing; and at least one indicator element mounted movably in the modular housing, and this at least one indicator element has marks indicating the amount of counter doses administered or remaining in the reservoir, and this at least one element The indicator is adapted to be able to move inside the modular housing in response to the successive administration of regulated doses with a medicine counter, in order to indicate the number of regulated doses administered or the remaining number of doses in the tank.
2. The indicating device according to claim 1, further characterized in that it includes the spout housing with a cavity mentioned above, wherein this spout housing includes a support cradle and a wall remote from that support cradle to form a space between the same, and that space defines at least a part of the aforesaid cavity, and the support cradle has a source configured to house a valve or pivot rod that extends from the reservoir, where the modular housing is placed inside. of the space between the wall and the support cradle described above.
3. The indicating device in accordance with the claim 1, further characterized in that the modular housing includes a viewing window, and the marks indicating the amount of regulated doses in the indicating element are visible to the user through the display window of the modular housing.
4. The indicating device in accordance with the claim 2, further characterized in that the dispenser housing also includes a viewing window, and the marks indicating the amount of regulated doses on the at least one indicating element can be seen by the user through the display window of the dispensing housing.
5. The indicating device according to claim 1, further characterized in that the modular housing includes a first and a second elements joined to form a closed enclosure.
6. The indicating device according to claim 1, further characterized by including a key adapted to be mounted to the tank, and wherein the modular housing has a keyhole formed therein, and the key is configured to enter that keyhole and allow the reservoir to be operatively connected to the spout housing.
7. The indicating device according to claim 6, further characterized in that the indicating module also includes an actuator element located in the modular housing and extending towards the interior of the keyhole, where the key is coupled with the actuator element when it enters the keyhole, and this actuator element is operatively and selectively connected to the at least one indicating element, in order to move this at least one indicator element in response to the successive administration of regulated doses with a medicine counter.
8. The indicating device according to claim 7, further characterized in that the modular housing includes an upper surface, and wherein the actuating element is substantially flush with this upper surface when it is decoupled from the key.
9. The indicating device according to claim 6, further characterized in that the keyhole includes a slot.
10. The indicating device according to claim 1, further characterized in that the at least one indicating element includes a variety of indicator elements.
11. The indicating device according to claim 10, further characterized in that it includes an actuator element adapted to operatively couple the reservoir, and this actuator element can be moved within the modular housing and selectively coupled with at least one of the diversity of indicator elements for moving this at least one indicator element in response to the aforementioned valve movement between the closed and open positions. 12.- The indicating device in accordance with the claim 11, further characterized in that it includes a spring disposed within the modular housing and engaging with the actuator element to drive this actuator element upwardly within the modular housing. 13. The indicating device according to claim 10, further characterized in that the diversity of indicating elements are mounted coaxially within the modular housing. 14. The indicating device according to claim 13, further characterized in that the modular housing also includes at least one coupling element, wherein the diversity of coaxially mounted indicator elements include at least a first and a second indicator element, wherein at least one of these first and second indicator elements includes an advancing element and at least the other of these first and second indicator elements includes a plurality of teeth or gears, wherein this at least one coupling element is adapted to couple in shape the advancing element selectively in order to place this advancing element in operative engagement with at least one of the diversity of teeth of the other first and second indicator members mentioned above, while the first indicator element rotates relative to the second indicator element , whereby the advance element makes the second element indi Please rotate in an incremental or progressive way. 15. The indicating device according to claim 14, further characterized in that it includes an actuator element mounted on the modular housing, and wherein the first indicating element includes a plurality of teeth, and the actuating element is adapted to selectively couple at least one of the diversity of teeth in the first indicator element for advancing or advancing the first indicator element incrementally or progressively in response to the movement of the valve. 16. The indicating device according to claim 14, further characterized in that it includes a third indicator element mounted coaxially in the modular housing with the first and second indicator elements, wherein at least one of the second and third indicator elements before mentioned includes an advancing element and at least the other of these second and third indicator elements includes a plurality of teeth, and this modular housing further includes at least a second coupling element, wherein the second coupling element is adapted to selectively couple the advancing element of at least one of the second and third indicator elements in order to drive the advancing element and operatively couple it with at least one of the tooth diversity of the other second and third indicating elements, while the second The indicator element rotates in relation to the third indicator element, so advance element causes the third indicator element to rotate in an incremental manner. 17.- The indicating device in accordance with the claim 14, further characterized in that the modular housing also includes at least one non-return element selectively coupled with at least one of the tooth diversity of at least one of the diversity of indicating elements. 18.- The indicating device in accordance with the claim 1, further characterized in that at least one indicator element includes an indicator wheel with a circumferential surface, wherein the marks indicating the amount of regulated doses are applied on the circumferential surface of the aforementioned indicator wheel. 19.- The indicating device in accordance with the claim 14, further characterized in that at least one of the diversity of indicator elements also includes a retaining device mounted coaxially with the indicator wheel and fixed thereto, and this retaining device includes a variety of teeth. 20. The indicating device according to claim 1, further characterized by including: a star wheel or ratchet mounted so that it can rotate in the modular housing; and a worm or serpentine mounted in the modular housing along a first axis of rotation, and this worm is connected to the ratchet wheel so that the rotation of this ratchet wheel rotates the worm gear around the first aforementioned rotation axis; and wherein the at least one indicating element includes a gear that engages the worm, and this gear is mounted in the modular housing on a second axis of rotation substantially perpendicular to the first axis of rotation of the worm. 21. The dispensing device according to claim 20, further characterized in that it includes an actuator element movably mounted in the modular housing, and this actuator element is selectively coupled with the aforementioned star or ratchet wheel in order to spinning this ratchet wheel in response to the administration of a regulated dose with a medicine counter. 22. The indicating device in accordance with the claim 1, further characterized in that the at least one indicator element mentioned above includes an indicator wheel with a flat face, and the marks indicating the amount of regulated doses are applied to this flat face of the indicator wheel so that the user can see them. 23.- The indicating device in accordance with the claim 2, further characterized in that the cavity of the spout housing has a longitudinal extension, and also includes the aforementioned reservoir, wherein the reservoir includes a valve stem or pivot extending longitudinally therefrom, and is movable between a closed position. and an open position, and the reservoir contains a variety of doses regulated with a dosimeter or medicine counter, and the valve stem supplies or delivers a dose of the dose diversity regulated with a counter when the valve stem is placed in the open position , and the reservoir is in the aforementioned housing cavity so that the valve stem described above is housed within the source, and the reservoir reciprocates within the housing along a longitudinal extension of the above-mentioned cavity. , so that the valve stem moves between the open and closed positions by coupling with n the support cradle in the above source; and further characterized in that the indicating module is operatively coupled with the reservoir, whereby at least one indicating element is displaced in response to reciprocal movement of the reservoir relative to the aforementioned dispensing housing. 24.- The indicating device in accordance with the claim 23, further characterized in that it includes a key mounted to the reservoir and wherein the modular housing has a keyhole formed therein, and the key is configured to penetrate the keyhole in order to allow the reservoir to move relative to the dispenser housing in such a way that the valve stem or pivot of the aforementioned tank is in the open position. 25.- The indicating device in accordance with the claim 24, further characterized in that the indicating module also includes an actuator element located in the modular housing and extending towards the interior of the keyhole, where the key engages with this actuator element when it enters the keyhole, and the actuator is connected operatively and selectively at least one indicator element described above. 26.- A dispenser or dispenser for administering regulated doses with medicine counter from a reservoir with a valve stem that extends longitudinally from that reservoir and that is movable between a closed position and an open position, and the aforementioned reservoir dispenses or administers the regulated dose with counter described above when the valve stem is placed in the open position, and this aerosol dispenser includes: a housing adapted to support the aforementioned reservoir that can move reciprocally within the housing as along a longitudinal axis, and this housing has a source adapted to house the valve stem and an exhaust port, and this source communicates with the orifice such that a dose regulated by a drug counter is administered through of the exhaust port when the valve stem is placed in the open position; a star or ratchet wheel mounted so that it can rotate in the housing and adapted to respond to the reciprocal movement of the aforesaid tank in the housing along the longitudinal axis described above, such that the longitudinal movement of the tank causes the ratchet wheel rotates; a worm mounted in the housing along a first axis of rotation substantially perpendicular to the longitudinal axis of the movement of the reservoir inside the housing, and this worm is connected to the aforesaid ratchet wheel in such a way that the rotation of the ratchet wheel causes the worm to rotate around the first axis of rotation; and an indicating element including a cylindrical gear coupled to that worm, and this cylindrical gear is mounted in the aforementioned housing on a second axis of rotation substantially perpendicular to the longitudinal axis of the movement of the tank inside the housing and the first axis of rotation of the screw, and this indicator element has visible marks for the user and that indicate the number of doses regulated with dosimeter or meter administered from, or remaining in, the deposit. 27. The spout or dispenser according to claim 26, further characterized in that it includes an actuator element movably mounted within the housing, and this actuator element is adapted to move in response to movement of the reservoir within the housing along the longitudinal axis, and to operatively engage with the ratchet wheel so as to rotate the ratchet wheel in response to longitudinal movement of the reservoir within the housing. 28. The dispenser according to claim 27, further characterized in that the actuating element includes a drive lever adapted to selectively engage and rotate the ratchet wheel. 29. - The dispenser according to claim 28, further characterized in that the actuator element also includes a ring adapted to engage with the reservoir and this ring is movably mounted in the housing, wherein the aforementioned drive lever extends in shape longitudinal from this ring. 30. The dispenser according to claim 27, further characterized in that it includes a spring that drives the actuator element, interrupting the operative coupling with the ratchet wheel. 31. The dispenser according to claim 30, further characterized in that the actuating element includes a post with an end adapted to be operatively coupled with the reservoir and a pull lever for selectively engaging with the ratchet wheel, and this spring is arranged around the pole and engages with it to urge the actuator element in such a way as to interrupt the selective engagement with the ratchet wheel. 32.- The dispenser according to claim 26, further characterized in that the previous element also includes an indicator wheel mounted coaxially with the aforementioned cylindrical gear, and this indicator wheel has indicative marks applied on a flat surface of the indicator wheel of so that the user can see them. 33. - The dispenser according to claim 26, further characterized in that the housing also includes a viewing window, and the indicative markings mentioned above can be seen through this viewing window. 34. The dispenser according to claim 26, further characterized in that the ratchet wheel and the worm are mounted coaxially within the aforementioned housing. 35.- The dispenser according to claim 26, further characterized in that it includes an indicator module formed by a modular housing, and this modular housing is located inside the aforementioned housing, wherein the ratchet wheel, the worm and The indicator element is mounted in such a way that it can rotate inside the modular housing. 36.- The dispenser according to claim 35, further characterized in that it includes a key adapted to be mounted to the tank, and where the modular housing has a keyhole formed therein and the key has the appropriate shape to penetrate the keyhole of such form that allows the tank to be operatively connected to the housing. 37.- An indicating device to indicate the number of doses regulated with dosimeter or meter of a drug, administered from or remaining in the reservoir, and the reservoir delivers these regulated doses with a counter when the valve is placed in the open position, and This indicator device includes: a housing formed by at least one coupling element; a plurality of indicator elements mounted coaxially in the housing and including at least one first and second indicator elements, and at least one of these indicator elements has marks indicating the amount of regulated doses and at least one of these first and second. second indicator elements include an advancing element and at least the other of these first and second indicator elements includes a plurality of teeth, wherein the coupling element is adapted to selectively engage with the advancing element in order to urge this element of advance so that it is operatively coupled with at least one of the teeth of the at least one indicator element mentioned above, while this first indicator element rotates relative to a second indicator element, in such a way that the advance element causes the Second indicator element turn incrementally or progressively. 38.- The indicating device according to claim 37, further characterized in that it includes an actuator element mounted in the aforesaid housing and responsive to the movement of the valve described above, and wherein the first indicator element includes a plurality of teeth, and this actuator element is adapted to be coupled with at least one of these teeth of the first indicator element in order to advance this first indicator element incrementally or progressively in response to the movement of the valve. 39. - The indicating device according to claim 38, further characterized in that it includes a spring arranged in the housing and adapted to drive the actuator element in such a way that it engages with the aforementioned reservoir. 40.- The indicating device in accordance with the claim 37, further characterized in that it includes a third indicator element coaxially mounted in the aforesaid housing with the first and second indicator elements, wherein at least one of the second and third indicator elements include an advancing element and at least the other of these second and third indicator elements include a plurality of teeth, and this housing also includes at least one second coupling element, wherein the second coupling element is adapted to selectively engage with the advancing member of at least one of the second and third indicator elements for the purpose of driving the advance element in such a way that it is operatively coupled with at least one of the various teeth of the other indicator element mentioned above, while this second indicator element rotates in relation to a third indicator element , whereby the advance element causes a third indicator element to rotate in Incremental or progressive. 41.- The indicating device in accordance with the claim 37, further characterized in that the housing also includes at least one anti-return element selectively coupled with at least one of the various teeth of at least one of the various indicator elements. 42. - The indicating device according to claim 41, further characterized in that the aforementioned coupling element and anti-return element are integrated in a single element. 43.- The indicating device according to claim 37, further characterized in that the coupling element includes an inclined surface. 44. The indicating device according to claim 37, further characterized in that the coupling element includes an elastic drag lever extending from the housing. 45.- The indicating device in accordance with the claim 37, further characterized in that the housing includes a modular housing arranged in a dispensing housing, wherein the diversity of indicating elements are mounted in the modular housing and the at least one coupling element is located inside the modular housing and wherein the The dispenser housing is adapted to support the aforementioned deposit. 46.- The indicating device according to claim 37, further characterized in that the housing includes a dispenser housing adapted to support the aforementioned deposit. 47.- The indicating device in accordance with the claim 37, further characterized in that the housing includes a viewing window, and the markings indicating the regulated doses can be seen by the user through that viewing window. 48. - The indicating device in accordance with the claim 37, further characterized in that at least one of the indicator elements includes an indicator wheel with a circular surface, and the marks indicating the amount of regulated doses are applied on this circular surface. 49.- The indicating device in accordance with the claim 48, further characterized in that at least one of the plurality of indicator elements also includes a retention device coaxially mounted with the indicator ratchet wheel and fixed thereto, and this retention device includes a variety of teeth. 50.- The indicating device according to claim 37, further characterized in that at least one of the indicator elements includes an indicator wheel that has a circumferential edge. 51.- The indicating device according to claim 50, further characterized in that the advancing element is formed by a part of the aforementioned circumferential edge. 52. The indicating device according to claim 50, further characterized in that the advancing element is disposed radially inwardly from the aforesaid circumferential edge. 53.- The indicating device in accordance with the claim 37, further characterized in that the advancing member includes a toothed portion adapted to engage with at least one of the plurality of teeth of the adjacent indicator element. 54. - The indicating device in accordance with the claim 37, further characterized in that it includes a key that has a portion of the key, and this key is adapted to be mounted to the tank, and wherein the housing includes a keyhole, configured to receive the portion of the aforementioned key. 55.- The indicating device to indicate the amount of doses regulated with dosimeter or meter of a drug administered from or remaining in a reservoir, and this reservoir has a valve stem that extends longitudinally and that can be moved between a closed position and an open position, and this reservoir administers the aforementioned regulated dose when the valve stem is placed in the open position, and this indicating device includes: a housing adapted to move relative to the aforementioned reservoir when the valve stem moves between the open position and the closed position; a plurality of indicator elements supported inside the housing in a coaxial and rotating manner, and each indicating element includes indicative markings on the circular surface thereof and visible to the user, and this diversity of indicating elements is selectively and operatively connected in such a manner. In this way, the successive movements of the tank relative to the housing rotate at least one of the aforementioned indicator elements, thereby changing the indicative mark visible to the user, in order to indicate that at least one regulated dose has been administered. accountant. 56. - The indicating device according to claim 55, further characterized in that the housing includes a modular housing arranged in a dispenser housing, and this dispenser housing is adapted to movably support the reservoir. 57.- The indicating device in accordance with the claim 55, further characterized in that the housing includes a dispenser housing adapted to support the reservoir. 58.- The indicating device according to claim 55, further characterized in that the diversity of indicating elements include at least a first and a second indicator elements, and the first indicating element is selectively and operatively coupled with the second indicating element by the successive rotations of the first indicator element mentioned above in such a way as to rotate the second indicator element in a incremental or progressive manner for each successive rotation of the first indicator element. 59.- The indicating device according to claim 58, further characterized in that it includes an actuator element adapted to be operatively coupled with the reservoir, wherein the actuator element is adapted to rotate the first indicator element in an incremental or progressive manner in response to the movement of the deposit in relation to the housing. 60.- A dispensing or discharging system to administer a medication to a user, and this dispensing system includes: a lodging; a deposit for the medication; and a key disposed in one of the aforementioned housing and tank, and the other of the aforementioned housing and tank have a keyhole; wherein the reservoir can be operatively connected to the housing when the key is shaped to penetrate the keyhole, and where the reservoir can not be operatively connected to the housing when the key is not shaped to penetrate in the keyhole. 61.- The dispensing system according to claim 60, further characterized in that the housing includes a spout housing with a cavity extending longitudinally and a source, and wherein the reservoir includes a valve stem, and this reservoir is operatively connected to the dispenser housing when the valve stem is mounted at the source such that the reservoir can be displaced reciprocally and longitudinally within the cavity. . 62.- The dispensing system according to claim 60, further characterized in that the key is arranged on the tank and the keyhole is configured on the housing. 63.- The dispensing system according to claim 61, further characterized in that it includes an indicating module that includes a modular housing and at least one indicating element mounted on said modular housing, wherein the aforementioned modular housing is arranged in the dispensing housing , wherein one of the keyhole and key mentioned above are configured on the housing of the indicator module. 64.- The dispensing system according to claim 61, further characterized in that the key is arranged on the housing and the keyhole is configured on the tank. 65.- A team consisting of components that can be assembled to create a dispensing device for the administration of dosed doses with a drug dosimeter from a reservoir, and this equipment includes: a housing with a cavity that extends longitudinally and a fountain located at the bottom of this cavity; a reservoir including a valve rod extending longitudinally therefrom, and this reservoir contains a variety of regulated doses with counter or dosimeter of the aforementioned medicament, and the valve stem described above is adapted to be housed in a source of the accommodation; and an indicating module including an indicating element, and this indicating module is adapted to be mounted in the bottom of the cavity of the above-described housing below the reservoir. 66.- A method for assembling or assembling a dispenser for administering dosed dosages of a medicament from a reservoir, and this method includes the steps of: providing a dispensing housing that includes a support cradle and a separate wall from the cradle of support in such a way that a space is created between them, and this cradle of support has a source; inserting an indicator module that includes at least one indicator element to indicate the amount of regulated doses remaining within or that have been administered from the aforementioned reservoir to the dispenser housing in the space between the aforementioned support cradle and wall of the housing pump; provide the aforementioned deposit, which includes a valve stem; inserting this valve stem of the aforementioned reservoir into the source of the support cradle in such a way that the reservoir is disposed in the dispenser housing above the indicator module described above. 67.- The method according to claim 66, further characterized in that the dispenser housing also includes a viewing window, wherein the indicating element is visible to the user through this viewing window. The method according to claim 66, further characterized in that the indicating module also includes a modular housing and an actuating element that extends upwardly from the modular housing and operatively engages the reservoir. 69.- A method for administering doses regulated with a dosimeter or counter of a substance from a reservoir with a valve stem that extends longitudinally therefrom and that can be moved between a closed position and an open position, and this reservoir administers a dose regulated when the valve stem is placed in the open position, and this method includes the steps of: providing a housing with a source and an exhaust port, and this source is communicated with the aforementioned exhaust port; provide a reservoir filled with a predetermined amount of counter-regulated doses, and this reservoir is movably supported within the housing along a longitudinal axis, and this reservoir includes a valve stem which is housed in the aforementioned source of the housing and which can be moved between a closed position and an open position while the reservoir moves longitudinally within the aforementioned housing, and this reservoir is adapted to discharge a regulated dose when the valve stem is placed in the open position; displacing the aforementioned reservoir on the longitudinal axis in order to move the valve stem and place it in the open position to discharge a regulated dose through the source and the aforementioned exhaust port; rotating a worm mounted on the housing until a predetermined angle is reached in response to the longitudinal movement of the tank described above, and this worm is mounted on an axis transverse to the aforementioned longitudinal axis of movement of the tank inside the housing; providing an indicator element mounted in the housing about an axis transverse to the longitudinal axis and the axis of the aforementioned worm, and this indicating element includes a cylindrical gear and indicative markings; and coupling this cylindrical gear with the worm to rotate the cylindrical gear on the axis transverse to the longitudinal axis and to the axis of the worm. 70. The method according to claim 69, further characterized in that it includes the steps of providing a ratchet wheel coaxially mounted to the aforementioned worm in the housing and rotating this ratchet wheel to rotate the aforementioned auger. 71.- The method according to claim 70, further characterized in that it includes the steps of coupling the actuator element with the aforementioned reservoir in such a way that the actuator element moves in response to the movement of the reservoir within the housing along the longitudinal axis, and coupling the ratchet wheel with the actuator element to rotate the ratchet wheel in response to longitudinal movement of the reservoir within the housing. 72. The method according to claim 71, further characterized in that the actuating element includes a drive lever with an end adapted to selectively engage and rotate the ratchet wheel. The method according to claim 72, further characterized in that the actuating element also includes a ring adapted to engage with the reservoir, and this ring is movably mounted in the housing and wherein the driving lever extends in longitudinal shape from this ring. 74. - The method according to claim 71, further characterized in that it includes a spring that moves the actuator away and interrupts the selective coupling with the ratchet wheel. The method according to claim 74, further characterized in that it includes a post mounted within the housing, and the spring is arranged around this post. The method according to claim 69, further characterized in that the indicator element also includes an indicator wheel coaxially mounted with the cylindrical gear, and this indicator wheel has marks applied on the face of the indicator wheel visible to the user. The method according to claim 69, further characterized in that the housing also includes a viewing window, and the indicative marks are visible to the user through this viewing window. 78. The method according to claim 70, further characterized in that the ratchet wheel and the auger are coaxially mounted within the housing. 79.- A method to administer regulated doses with a substance counter from the deposit, and this method includes the steps of: providing a lodging; providing a reservoir filled with a predetermined amount of regulated doses with a substance counter, and this reservoir is supported in the above-mentioned housing, and this reservoir includes a valve that can be moved between a closed position and an open position, and this reservoir is adapted to discharge a regulated dose when the aforementioned valve is placed in the open position; place the valve in the open position to discharge a regulated dose with counter; place the valve in the closed position; rotating the first indicator element mounted in such a way that it can rotate in the housing advancing a predetermined distance in response to at least one of the aforementioned movements of the valve; rotating a second indicator element such that it advances a predetermined distance due to a predetermined amount of movements of the valve and in response to the rotation of the first indicator element, and this second indicator element is coaxially mounted in the housing with the first element indicator; and providing indicia indicative of at least some of the first and second indicator elements. 80.- The method according to claim 79, further characterized in that the housing includes a source and an exhaust hole, and this source is communicated with this exhaust hole, and wherein the reservoir includes a valve stem that is housed in the aforementioned source and housing, and wherein placing this valve in the open position includes displacing the reservoir relative to the housing in order to move the valve stem. valve to the open position, and wherein placing the valve in the closed position includes moving the reservoir relative to the housing in order to place the valve stem in the closed position, and wherein the rotational movement of the first indicator element is in response to at least one of the movements of the tank in relation to the aforementioned housing. The method according to claim 80, further characterized in that it includes the steps of coupling the actuator element to the reservoir such that the actuator member moves in response to the movement of the reservoir within the housing along the longitudinal axis , and coupling the first indicator element with the actuator element in order to rotate the first indicator element such that it advances a predetermined distance in response to longitudinal movement of the reservoir within the housing. 82. The method according to claim 81, further characterized in that the actuating element includes a drive lever with an end adapted to selectively drive and rotate the first indicator element. 83. The method according to claim 79, further characterized in that the first indicator element includes an advancing element and the second indicator element mentioned above includes a variety of teeth, and wherein the housing includes at least one coupling element, and wherein the step of rotating the second indicator element also includes rotating the first indicator element in such a way that the aforementioned coupling element urges the advancing element to engage with at least one of the diversity of teeth of the second indicator element for the purpose of rotating the second indicator element with the first indicator element.