MXPA00002904A - Low residue solid antiperspirant - Google Patents

Abstract

The present invention is directed to a low residue antiperspirant composition substantially free of water and long chain fatty alcohols which comprises:(a) from about 30%to about 50%of a volatile silicone;(b) from about 5%to about 30%of a particulate antiperspirant active;(c) from about 2%to about 12%of hydrogenated castor oil;(d) from about 8%to about 28%of paraffin;and (e) from about 10%to about 25%of an emollient;wherein the ratio of the paraffin to hydrogenated castor oil is from about 6 to 1 to about 0.85 to 1.

Description

LOW RESIDUE SOLID ANTITRANSPIRANT DESCRIPTION OF THE INVENTION The present invention relates to antiperspirant bars, substantially free of water and long-chain fatty alcohols, which provide the user with excellent anmitic efficacy, reduce waste when the composition is first applied to the skin , reduce waste after drying, high temperature stability, and excellent cosmetic and aesthetic.

BACKGROUND OF THE INVENTION Many solid antiperspirants have been described in the chemical and cosmetic literature. These compositions generally tend to fall into one of two classes: emulsion sticks and suspension bars. The emulsion bars contain a solution of the active ingredient incorporated in the bar by means of an emulsion. Although emulsion sticks may be desirable in certain aspects, they tend to be unstable, have poor aesthetics and leave a visible residue on the skin after use. The suspension rods contain the pulverized active antifreeze suspended in the bar without the use of water or an emulsion. While suspensoids tend to be stable, they can be brittle and hard and more importantly, they tend to leave an unpleasant white chalky residue after application. This waste is not only aesthetically unpleasant to the user, but it can also dirty the clothes. The present invention provides an excellent antimicrobial composition that does not leave a limy white residue on the application. The excellent antiperspirant compositions of the invention are frequently in the form of suspension rods. The patents and patent documents related to this field of the invention are as follows: USP 3,255,082; Barton et al; USP 3,986,203; Spitzer et al; USP 4,083,956 S he 1 ton; EPA 28,853 Bec meyer et al; USP 4,425,328, Nabial et al; USP 4,265,878, Keil; USP 4,229,432, Geria; USP 4,724,139, Palinczar USP 4,985,238 Tanner et; and USP 5,486,347, Callaghan et al.

EP-A-295070 discloses antiperspirant compositions containing essentially a polyhydric alcohol, which in practice solubilizes the antiperspirant, while in the present invention the antiperspirant is in particulate form. EP-A-388110 describes creams that are thickened with an inorganic material, particularly clay together with an additional essential constituent, an activator for the clay. The present invention does not employ a clay-based system to introduce the structure to the composition. O-97/15270 describes a cosmetic product that essentially contains a dispersed particulate alkali metal or ammonium bicarbonate. WO 97/16162 discloses an antiperspirant cream that is structured using a silicone wax of the specified formula. None of EP-A-295070, EP-A-388110, WO-97/15270 or O-97/16162 discloses the preparation of structured compositions with the inventive combination of wax structurants within the specific ratio range.

SUMMARY OF THE INVENTION The present invention is directed to a low residue antiperspirant composition substantially free of water and long chain fatty alcohols comprising: (a) from about 30% to about 50% of a volatile silicone; (b) from about 5% to about 30% of a particulate active antiperspirant; (c) from about 2% to about 12% hydrogenated castor oil; (d) from about 8% to about 28% paraffin wax; and (e) from about 10% to about 25% of an emollient; wherein the ratio of the paraffin wax to the hydrogenated castor oil is from about 6 to 1 to about 0.85 to 1. The present invention is also directed to a method for preventing and controlling the transpiration of moisture in humans comprising the application to the area under the armpits of an effective amount of the composition as above.

DETAILED DESCRIPTION OF THE INVENTION As used herein,% means% by weight, unless otherwise specified. All of the ingredients used to prepare the compositions of the invention are known. The present invention is directed to a low residue antiperspirant composition substantially free of water and long chain fatty alcohols comprising: (a) from about 30% to about 50% of a volatile silicone; (b) from about 5% to about % of a particulate active antiperspirant; (c) from about 2% to about 12% hydrogenated castor oil; (d) from about 8% to about 28% paraffin wax; and (e) from about 10% to about 25% of an emollient; wherein the ratio of paraffin wax to hydrogenated castor oil is from about 6 to 1 to about 0.85 to 1. The present invention is also directed to a composition as in the foregoing wherein the ratio of paraffin wax to oil of hydrogenated castor is about 4 to 1 to about 1. The present invention is also directed to a composition as above wherein the ratio of paraffin wax to hydrogenated castor oil is from about 4 to 1 to about 1 to 1, and particularly from about 2 to 1 to about 1 to 1.

The present invention is also directed to a composition such as the above, wherein the volatile silicone is present in a range of approximately 35% to about 45%. The present invention is also directed to a composition as the above, wherein the particulate active antitranspipe is present in a range of about 20% to about 25%. The present invention is also directed to a method for preventing and controlling moisture transpiration in humans comprising the application to the area under the armpits of an effective amount of the composition as above. The present invention is also directed to the process for repairing antiperspirant compositions of the invention.

PARAFFINIC HYDROCARBON, Branched chain hydrocarbons useful in the present invention are non-volatile branched aliphatic waxes. Paraffin is a solid mixture of hydrocarbons obtained from petroleum, characterized by relatively large crystals.

The preferred branched hydrocarbon used in the compositions of the invention is paraffin. A paraffin material that can be used in the present invention is available under the trademark "Paraffin Wax S.P. 173" sold by Strahl & Pitsch, Inc. P.O. Box 1098 West Babylon, NY 11704 (516) 587-9000 Specifies the following: Melting Point - USP Class II - open capillarity tube 136 - 142F Penetration - ASTM D-1321 @ 100/77/5 10-16.

PREVENTING MATERIALS The present compositions contain from about 5% to about 30% by weight of a particulate antiperspirant material. These percentages by weight are calculated in anhydrous metal salt bases (exclusive of glycine, glycine salts, or other complex agents). The particulate antiperspirant material preferably has particle sizes ranging from about 1 to about 100 microns, more preferably from about 1 to about 50 microns. They may be in impalpable or microscopic form and preferably have a high bulk density (eg, more than approximately 0.7 g / cm '. Such materials include, for example, many astringent aluminum or zirconium salts or complexes and are well known in the art. Any astringent antiperspirant salt of aluminum or astringent complex of aluminum and / or zirconium in particulate form can be employed herein.Salts useful as astringent antiperspirant salts or as components of astringent complexes include aluminum halides, hydr ox i ha 1. aluminum ions, zirconyl oxy halides, zirconyl oxyhalides and mixtures of these salt materials Aluminum salts of this type include aluminum chloro-and the hydroxyaluminium halides have the general formula Al2 (OH ) xQyXH20 where Q is chlorine, bromine, or iodine; x is from about 2 to about 5, and x + y is about 6 yxyy does not need to be integers and where X is from about 1 to about 6. Aluminum salts of this type can be prepared in the manner described more fully in USP 3,887,692 to Gilman, USP 3,904,741 Jones and Rubino, both of which are incorporated herein by reference. Zirconium salts which are useful in the present invention include zirconium oxy salts and hydroxy zirconium salts, also referred to as hydroxy zirconyl salts. These compounds can be represented by the following general formula: ZrO (OH) 2-nzBz wherein z can vary from about 0.9 to about 2 and does not need to be an integer, n is the valence of B, 2-nz is greater than, or equal to 0, and b may be selected from the group consisting of halides, nitrate, sulfamate, sulfate, and mixtures thereof. Although only zirconium and aluminum compounds are exemplified in the invention, it will be understood that other metals such as Group IV metals, including hafnium, could be used in the present invention. As with the basic aluminum compounds, it will be understood that the above formula is greatly simplified and is intended to represent and include compounds having coordinated and / or bound water in various amounts as well as polymers, mixtures and complexes thereof. As will be seen from the above formula, hydroxy zirconium salts currently represent a range of compounds having various amounts of the hydroxy group, ranging from about 1.1 to only slightly greater than 0 groups per molecule. Various types of antiperspirant complexes utilizing the above antiperspirant salts are known in the art. For example, 3,792,068 Luedders et al., Discloses complexes of aluminum, zirconium and amino acids such as glycines. Complexes such as those described in Luedders and other similar complexes are commonly known as ZAG (OR Zag). The ZAG complexes are chemically analysable by the presence of aluminum, activated ZAG compounds and chlorine. The ZAG complexes useful herein are identified by the specification of the molar ratio of aluminum to zirconium (the Al ratio; Zr) and the molar ratio of the total metal to chlorine (metal: C1) ZAG complexes useful in the present they have an Al: Zr ratio of about 1.67 to about 12.5 and a metal: C1 ratio of about 0.73 to about 1.93.

Another patent describing the ZAG compounds is USP 4,985,238 to Tanner et al. This precisely mentioned patent is incorporated herein by reference. Preferred ZAG complexes are described in USP 4,985,238 to Tanner et al. Another patent describing activated ZAG compounds (AZAG or AZG compounds) is USP 5,486,347 a Callaghan et al. This precisely mentioned patent is incorporated herein by re f er on. The activated ZAG compounds can be used as the particulate active antiperspirant in the compositions of the present invention. The ZAG compounds can be prepared by heating an aqueous solution containing an aluminum component or an aluminum component and mixing it with a hydroxy zirconium chloride component.

SIL I VOLATILE CONA Volatile silicones are known for use in deodorant sticks. The volatile silicone component is preferably either a cyclic or linear polymethylene or 1 oxane and is present at a level of from about 30 to about 50%, preferably from about 35% to about 45%. Volatile silicones are more fully described in USP 4,985,238 which is incorporated herein by reference.

HYDROGENATED RICINO OIL Hydrogenated castor oil is the final product of the controlled hydrogenation of castor oil and is described on page 315 of the International Cosmetic Ingredient Dictionary 5th ed., 1993, which is incorporated herein by reference.

EMOLLIENT Emollients suitable for use in the compositions of the present invention are known in the art and include a non-volatile silicone oil, a high molecular weight polyol, a surfactant-oil, an aromatic ester, an aliphatic ester, and organic compounds Similar.

OPTIONAL INGREDIENTS In addition to the ingredients listed above, the anhydrous, topically effective compositions of the present invention may also include other optional ingredients which are preferably included in cosmetic and topical medicinal compositions. For example, fragrances may be incorporated into the anhydrous, topically effective composition in an amount of from about 0% to about 5% based on the total weight of the composition. The composition of the present invention, when applied to the skin, therefore fixes a substantive fragrance film on the skin that resists moisture, but which can be removed by washing. Other optional ingredients that can be included in the anhydrous composition of the present invention include, but are not limited to, drying agents, such as talc or DRY FLO (or c t in the aluminum starch ucc ร ina t); conservatives; and dyes. generally, such optional ingredients are present in a composition of the present invention in an amount of about 10% or less by weight. In addition, although the need to include an organic clay is virtually eliminated for the use of the new and improved suspending agent, an organic clay may be included in a composition of the present invention as an additional suspending agent in an amount of up to 20. % by weight of the composition. An organic clay is especially useful as an anti-agglutinating agent to maintain a topically effective particulate compound dispersed throughout the composition. An exemplary organic clay is a quaternized three-layer clay exfoliated with a polar solvent, similar to a monothermal clay on quaternized exfoliated with propylene carbonate. The compositions of the invention are prepared by combining all the ingredients, except the active antiperspirant, the fragrance (if present) and the talc (if present). The resulting mixture is heated with stirring to a temperature of about 74 ° C (165 ° F) to about 85 ° C (185 ° F), until all the waxes are completely melted or until all the particles are well dispersed. The active antiperspirant, and talcum (if present) are added to the melted wax at any temperature between about 74 ° C (165 ° F) at approximately 85 ° C (185 ° F). The fragrance (if present) is added at approximately 74 ° C (165 ° F). The mixture is then filled in baskets at 74 ° C (165 ° F) or cooled to a temperature in the range of about 63 ° C (145 ° F) to about 74 ° C (165 ° F) and then filled in baskets . It is preferred to fill the baskets when the mixture is at 74 ° C (165 ° F). In the baskets, the compositions are also cooled to room temperature and harden. The following specific examples are illustrative of the anhydrous, topically effective compositions of the present invention. However, it should be understood that the present invention is not limited to specific examples set forth below. In the following examples, all the amounts of the various ingredients are expressed by weight percentages unless otherwise specified.

The numbers in the previous table are by weight Examples I, J, _K, L ,, M, N, 0, _ P, Q and R The ingredients in the following tables are in% by weight.

The compositions of the present invention are excellent antiperspirant compositions that do not leave a calcareous white residue to the application. This can be demonstrated by applying the compositions of the present invention to a dark substrate and measurably measuring the intensity of any resulting moisture. An important physical parameter that affects consumer acceptance of antiperspirant sticks of the invention is hardened as measured by needle penetration. Typical compositions of the invention will vary in hardness from about 7.0 to about 14.0 mm as shown by the needle penetration test mentioned above. Products outside this range will typically generate low consumer acceptance ratings. The following experimental results demonstrated the properties of the remelted compositions.

Summary of Experimental Methods An in vitro method was used to quantify the relative amount of bleaching of two antiperspirant sticks. The formulas of these two bars are shown below. At a 95% safety, instrumental luminosity measurements using a stopwatch shows the residue of Composition 1 to be significantly whiter than that of Composition 2 one minute after application on gray sandpaper. After two hours of drying at room temperature, the residue of Composition 1 is whiter than after application, while the residue of Composition 2 is less white than after the application and is not significantly different from the paper of sandpaper Visual observation of the treated sandpaper indicates that Composition 2 is very clear, while the residue of Composition 1 is very white.

Method The surface of the bars were cut with a knife to produce a flat surface for application. The bars were applied by hand, presenting a similar pressure, sandpaper sand gray 1200 (Grainder). Each application consists of 4 strokes that cover an area of 2.5 x 20 cm (50 cm2). Three duplicate applications of each product were made. The Minolta Chromametere was established to read in L * a * b by measuring the mode and was used to measure the color of the residue of the formulation in the sandpaper. One minute after the application, the L * value, a brightness measurement (whiteness), was acquired at five sites in each application area. The most uniform areas were used for the measurement sites and the end was avoided due to the "fingerprint" bar present. Thus, fifteen measurements were obtained for each formulation one minute after the application. The bar residue on the sandpaper was allowed to dry for two hours at room temperature. The L * value was again acquired at the five sites in each application area, producing fifteen measurements for each formulation. The differences between the two formulations and the sandpaper at these two time points were determined using analysis of variance followed by a post-hoc Scheffe test at p < 0.05.

Scheffe test; Variable L * - 1 minute after the application of the products.

Marked differences are significant in p < 0.5000 Scheffe test; Variable: L * - 2 hours after the application of the products.

"Marked differences are significant at p < 0.5000 Conc lu s_i on e s A high L * value indicates a lighter (whiter) formulation on the sandpaper substrate.

One minute, after the application: The results indicated that the residue of Composition 1 is whiter than that of Composition 2. The results of the Scheffe test show that this difference is significant at the 95% confidence level. This statistical analysis, at a confidence level of 95%, shows that the residue of composition 2 is white as the sandpaper at this point of time of a minute.

Two hours after the application: The residue of Composition 1 is much whiter than that of Composition 2. The residue of Composition 2 is less white after drying, that was 1 minute after the application, and the results of the Scheffe test, at a confidence level of 95%, showed that this residue is not significantly different in sanding paper whiteness at this time point of 2 hours.

Visual observations of the sand paper after drying for hours, hours: The residue of Composition 2 on the sandpaper is colorless, while the Composition 1 is extremely white.

In a manner similar to the following Compositions, 3 and 4 were tested for a relative amount of whiteness.

Results Sclieffe test: Variable: VALUE L * - After the product was dried in homogeneous groups of sandpaper, p < 0.05 The results of the Scheffe test indicated that, at the 95% confidence level, there was no significant difference in whiteness between the residue of Composition 3 and the sandpaper with none applied. The residue of Composition 4, which contains stearyl alcohol is significantly whiter than the residue of Composition 3 and also the sanding paper.

Compositions 3 and 4 are as follows Conclusions An elevated L * indicates a whiter formulation residue on the sandpaper substrate. After drying at room temperature, the residue of composition 4 is significantly whiter than the residue of Composition 3. The statistical analysis of the results also showed that, at the 95% confidence level, the residue of Composition 3 does not it is significantly different in whiteness from untreated sandpaper.

Claims (9)

1. CLAIMS 1. A low residue antiperspirant composition - substantially free of water and long chain fatty alcohols comprising: (a) from about 30% to about 50% of a volatile silicone; (b) from about 5% to about 30% of a particulate active antiperspirant; (c) from about 2% to about 12% of a hydrogenated castor oil; (d) from about 8% to about 28% of a paraffin wax; and (e) from about 10% to about 25% of an emollient; characterized in that the ratio of the paraffin wax to the hydrogenated castor oil is from about 6 to 1 to approximately 0.85 to 1.
2. 2. A composition according to claim 1, characterized in that the ratio of paraffin wax to oil of Hydrogenated castor is about 4 to 1 to about l.
3. 3. A composition according to any preceding claim 1, characterized in that the ratio of the paraffin wax to the hydrogenated castor oil is from about 2 to 1 to about 1 to 1.
4. 4. A composition according to the rei indication 1, characterized in that the volatile silicone is present in a range of approximately 35% to approximately 45%.
5. 5. A composition according to any of the preceding indications, characterized in that the particulate active antiperspirant is present in a range of approximately 20% to approximately 25%.
6. 6. A method for preventing and controlling moisture transpiration in humans, comprising applying to the area under the armpits an effective amount of the composition according to claim 1.
7. 7. A process for preparing a composition in accordance with claim 1, which complies: (1) combine: (a) a volatile silicone; (b) hydrogenated castor oil; (c) paraffin wax; and (d) an emollient; characterized in that the ratio of the paraffin wax to the hydrogenated castor oil is from about 6 to 1 to about 0.85 to 1; (2) the resulting mixture is heated with stirring at a temperature of about 74 ° C to about 85 ° C, until all of the waxes are completely melted or until all of the particles are well dispersed; (3) add an active antiperspirant, and (4) fill the mixture in a basket to 74 ° C; or cooling the mixture to a temperature in the range of about 63 ° C to about 74 ° C, filling the mixture in a basket; and (5) allow the mixture to cool to room temperature and harden.
8. 8. A process according to the rei indication 7, characterized in that the mixture in step 4 is filled in a basket when the mixture is at about 74 ° C.
9. 9. A process according to claim 7, characterized in that in step 3, the active antiperspirant is filled at 85 ° C and where in step 3, the talc is further added at 85 ° C.