MX9805299A - Novedosos polinucleotidos panc1a y panc1b asociados con cancer pancreatico. - Google Patents

Novedosos polinucleotidos panc1a y panc1b asociados con cancer pancreatico.

Info

Publication number
MX9805299A
MX9805299A MX9805299A MX9805299A MX9805299A MX 9805299 A MX9805299 A MX 9805299A MX 9805299 A MX9805299 A MX 9805299A MX 9805299 A MX9805299 A MX 9805299A MX 9805299 A MX9805299 A MX 9805299A
Authority
MX
Mexico
Prior art keywords
panc1b
panc1a
pancreatic cancer
polypeptide
provides
Prior art date
Application number
MX9805299A
Other languages
English (en)
Inventor
Richard D Goold
Ingrid E Akerblom
Jeffrey J Seilhamer
Roger Coleman
Original Assignee
Incyte Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/581,240 external-priority patent/US5840870A/en
Application filed by Incyte Pharma Inc filed Critical Incyte Pharma Inc
Publication of MX9805299A publication Critical patent/MX9805299A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas

Abstract

La presente invencion proporciona secuencias de polinucleotidos designados PANC1A y PANC1B, los cuales se asocian con una secuencia genomica relacionada al cáncer pancreático así como otros cánceres. La presente invencion también proporciona moléculas antisentido de PANC1A y PANC1B. La invencion proporciona además vectores de expresion genéticamente diseñados y células huésped para la produccion de polipéptido PANC1A y PANC1B purificados; anticuerpos, antagonistas e inhibidores de polipéptido PANC1A y PANC1B; y composiciones farmacéuticas y métodos de tratamiento basados en el polipéptido, sus anticuerpos, antagonistas e inhibidores. La invencion proporciona específicamente el uso del polipéptido como una composicion diagnostica para la deteccion de cáncer pancreático en individuos en riesgo para y expuestos a cáncer pancreático. La invencion también se refiere a métodos terapéuticos y composiciones basadas en las secuencias de nucleotidos para PANC1A y PANC1B.
MX9805299A 1995-12-29 1998-06-29 Novedosos polinucleotidos panc1a y panc1b asociados con cancer pancreatico. MX9805299A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/581,240 US5840870A (en) 1995-12-29 1995-12-29 Polynucleotides PANC1A and PANC1B associated with pancreatic cancer
US08/616,392 US5998165A (en) 1995-12-29 1996-03-15 Polynucleotides encoding a protein associated with pancreatic cancer

Publications (1)

Publication Number Publication Date
MX9805299A true MX9805299A (es) 1998-10-31

Family

ID=27078250

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9805299A MX9805299A (es) 1995-12-29 1998-06-29 Novedosos polinucleotidos panc1a y panc1b asociados con cancer pancreatico.

Country Status (7)

Country Link
US (1) US5998165A (es)
EP (1) EP0870021A1 (es)
JP (1) JP2000502902A (es)
AU (1) AU722904B2 (es)
CA (1) CA2241317A1 (es)
MX (1) MX9805299A (es)
WO (1) WO1997024437A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999031274A2 (en) * 1997-12-15 1999-06-24 Abbott Laboratories Reagents and methods useful for detecting diseases of the pancreas
CA2395295A1 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins and antibodies
US20040097442A1 (en) * 2002-11-16 2004-05-20 Isis Pharmaceuticals Inc. Modulation of BRCA2 region transcription unit CG005 expression
US8753435B2 (en) * 2006-04-03 2014-06-17 Ric Investments, Llc Portable oxygen concentrator
JP5212893B2 (ja) 2008-05-09 2013-06-19 住友ベークライト株式会社 Ｎ結合型糖鎖を利用した膵臓癌の診断方法
WO2011126053A1 (ja) 2010-04-06 2011-10-13 国立大学法人鹿児島大学 Ｎ結合型糖鎖を利用した消化器癌の検査方法
KR101373103B1 (ko) 2011-03-28 2014-03-11 연세대학교 산학협력단 Ｐａｕｆ 및 그의 결합 파트너의 상호작용을 이용한 암 치료제의 스크리닝 방법
JP2013083490A (ja) 2011-10-06 2013-05-09 Kagoshima Univ 消化器癌診断用マーカー、および消化器癌の検査方法

Also Published As

Publication number Publication date
JP2000502902A (ja) 2000-03-14
US5998165A (en) 1999-12-07
AU1421197A (en) 1997-07-28
WO1997024437A1 (en) 1997-07-10
CA2241317A1 (en) 1997-07-10
EP0870021A1 (en) 1998-10-14
AU722904B2 (en) 2000-08-17

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