MX9800995A - Inhibidores de la transduccion de señales mediada por el factor asociado al receptor del factor de necrosis de tumores. - Google Patents

Inhibidores de la transduccion de señales mediada por el factor asociado al receptor del factor de necrosis de tumores.

Info

Publication number
MX9800995A
MX9800995A MX9800995A MX9800995A MX9800995A MX 9800995 A MX9800995 A MX 9800995A MX 9800995 A MX9800995 A MX 9800995A MX 9800995 A MX9800995 A MX 9800995A MX 9800995 A MX9800995 A MX 9800995A
Authority
MX
Mexico
Prior art keywords
traf
inhibitors
trafs
pharmaceuticals
nucleic acid
Prior art date
Application number
MX9800995A
Other languages
English (en)
Other versions
MXPA98000995A (es
Inventor
David V Goedel
Mike Rothe
Original Assignee
Genentech Inc
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Tularik Inc filed Critical Genentech Inc
Publication of MX9800995A publication Critical patent/MX9800995A/es
Publication of MXPA98000995A publication Critical patent/MXPA98000995A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion se relaciona a inhibidores novedosos de la tranduccion de señales mediada por el factor asociado al receptor del factor de necrosis de tumores (TRAF). La invencion incluye las proteínas inhibidoras novedosas (I-TRAFa), los ácidos nucleicos que los codifican, los métodos para su produccion recombinante, y su uso en ensayos de seleccion, y como compuestos farmacéuticos.
MXPA/A/1998/000995A 1995-08-17 1998-02-04 Inhibidores de la transduccion de señales mediada por el factor asociado al receptor del factor de necrosis de tumores MXPA98000995A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US238295P 1995-08-17 1995-08-17
US002382 1995-08-17

Publications (2)

Publication Number Publication Date
MX9800995A true MX9800995A (es) 1998-10-31
MXPA98000995A MXPA98000995A (es) 1999-01-11

Family

ID=

Also Published As

Publication number Publication date
NZ315514A (en) 1998-12-23
ATE291585T1 (de) 2005-04-15
US6063585A (en) 2000-05-16
EP0845005A1 (en) 1998-06-03
DE69634512T2 (de) 2006-02-09
US20040087774A1 (en) 2004-05-06
US6060303A (en) 2000-05-09
DE69634512D1 (de) 2005-04-28
EP1568708A2 (en) 2005-08-31
JP2009065981A (ja) 2009-04-02
IL122980A0 (en) 1998-08-16
US6294348B1 (en) 2001-09-25
US5789550A (en) 1998-08-04
EP0845005B1 (en) 2005-03-23
AU6723796A (en) 1997-03-12
AU709535B2 (en) 1999-09-02
JP4382878B2 (ja) 2009-12-16
JPH11511967A (ja) 1999-10-19
EP1568708A3 (en) 2005-10-12
US6004553A (en) 1999-12-21
DK0845005T3 (da) 2005-08-01
ES2239334T3 (es) 2005-09-16
WO1997007134A1 (en) 1997-02-27
CA2227174A1 (en) 1997-02-27
ZA966663B (en) 1998-02-06

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees