MX9709542A - Modulation of calcium channels. - Google Patents

Modulation of calcium channels.

Info

Publication number
MX9709542A
MX9709542A MX9709542A MX9709542A MX9709542A MX 9709542 A MX9709542 A MX 9709542A MX 9709542 A MX9709542 A MX 9709542A MX 9709542 A MX9709542 A MX 9709542A MX 9709542 A MX9709542 A MX 9709542A
Authority
MX
Mexico
Prior art keywords
calcium channels
modulation
pharmaceutically
alkyl
phenyl
Prior art date
Application number
MX9709542A
Other languages
Spanish (es)
Other versions
MXPA97009542A (en
Inventor
Nancy Louise Bowling
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX9709542A publication Critical patent/MX9709542A/en
Publication of MXPA97009542A publication Critical patent/MXPA97009542A/en

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  • Hydrogenated Pyridines (AREA)

Abstract

A method for modulating calcium channels, increasing the density of calcium channels in vascular and cardiac tissue with no changes in inotropic or pressor response, comprising administering to a warm-blooded animal in need thereof a pharmaceutically-effective amount of a compound having formula (I) wherein R1 and R3 are independently hydrogen, C1-C4 alkyl, -CO-(C1-C6 alkyl), or -CH2Ar, -CO-Ar, wherein Ar is phenyl or substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically-acceptable salt thereof.
MXPA/A/1997/009542A 1995-06-07 1997-12-04 Modulation of cal calc MXPA97009542A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60916195A 1995-06-07 1995-06-07
US08485317 1995-06-07

Publications (2)

Publication Number Publication Date
MX9709542A true MX9709542A (en) 1998-03-31
MXPA97009542A MXPA97009542A (en) 1998-10-15

Family

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees