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Application filed by Connaught LabfiledCriticalConnaught Lab
Publication of MX9709525ApublicationCriticalpatent/MX9709525A/en
Measuring Or Testing Involving Enzymes Or Micro-Organisms
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Peptides Or Proteins
(AREA)
Abstract
Vectors containing a nucleotide sequence coding for an F protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described. Such vectors also may contain a further nucleotide sequence located adjacent to the RSV F protein encoding sequence to enhance the immunoprotective ability of the RSV F protein when expressed in vivo. Such vectors may be used to immunize a host, including a human host, by administration thereto. Such vectors also may be used to produce antibodies for detection of RSV infection in a sample.