MX9708915A - Compositions of interleukin and pyrimidine nucleosides. - Google Patents

Compositions of interleukin and pyrimidine nucleosides.

Info

Publication number
MX9708915A
MX9708915A MX9708915A MX9708915A MX9708915A MX 9708915 A MX9708915 A MX 9708915A MX 9708915 A MX9708915 A MX 9708915A MX 9708915 A MX9708915 A MX 9708915A MX 9708915 A MX9708915 A MX 9708915A
Authority
MX
Mexico
Prior art keywords
interleukin
compositions
pyrimidine nucleosides
derivative
fluorouracil
Prior art date
Application number
MX9708915A
Other languages
Spanish (es)
Other versions
MXPA97008915A (en
Inventor
Kazushige Mori
Yutaka Tanaka
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX9708915A publication Critical patent/MX9708915A/en
Publication of MXPA97008915A publication Critical patent/MXPA97008915A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A synergistic antitumor pharmaceutical composition comprising an effective amount of interleukin-12 and a pyrimidine nucleoside derivative as well as a hydrate or solvate thereof that is converted into fluorouracil or its derivative, and a pharmaceutically acceptable carrier.
MXPA/A/1997/008915A 1995-05-26 1997-11-19 Compositions of interleucine and nucleosides of pirimid MXPA97008915A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95108063.9 1995-05-26
EP95108063 1995-05-26
PCT/EP1996/002088 WO1996037214A2 (en) 1995-05-26 1996-05-15 Compositions of interleukin and pyrimidine nucleosides

Publications (2)

Publication Number Publication Date
MX9708915A true MX9708915A (en) 1998-03-31
MXPA97008915A MXPA97008915A (en) 1998-10-15

Family

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Also Published As

Publication number Publication date
JPH10506641A (en) 1998-06-30
CN1184430A (en) 1998-06-10
AU5998296A (en) 1996-12-11
WO1996037214A2 (en) 1996-11-28
TR199701435T1 (en) 1998-03-21
CA2220837A1 (en) 1996-11-28
BR9608779A (en) 1999-07-06
WO1996037214A3 (en) 1997-01-09
EP0828508A2 (en) 1998-03-18
AR005417A1 (en) 1999-06-23

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