MX9708363A - Aplicacion de mutantes que transportan glucosa para la produccion de compuestos de la via aromatica. - Google Patents

Aplicacion de mutantes que transportan glucosa para la produccion de compuestos de la via aromatica.

Info

Publication number
MX9708363A
MX9708363A MX9708363A MX9708363A MX9708363A MX 9708363 A MX9708363 A MX 9708363A MX 9708363 A MX9708363 A MX 9708363A MX 9708363 A MX9708363 A MX 9708363A MX 9708363 A MX9708363 A MX 9708363A
Authority
MX
Mexico
Prior art keywords
production
glucose
application
pathway
glucose transport
Prior art date
Application number
MX9708363A
Other languages
English (en)
Other versions
MXPA97008363A (es
Inventor
Fernando Valle
Noemi Mejia
Alan Berry
Original Assignee
Genencor Int
Univ Nac Autonoma De
Mexico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int, Univ Nac Autonoma De, Mexico filed Critical Genencor Int
Publication of MX9708363A publication Critical patent/MX9708363A/es
Publication of MXPA97008363A publication Critical patent/MXPA97008363A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Esta invencion describe los métodos para aumentar el flujo de carbono hacia una vía de una célula huésped para aumentar la produccion biosintética de compuestos del mismo, las células huésped se selecciona en base al fenotipo Pts/glucosa. Tales células huésped son capaces de transportar glucosa sin consumir PEP, dando como resultado la conservacion del PEP, el cual puede ser redirigido a la vía para aumentar la produccion de los compuestos deseados a lo largo de la vía. Los mutantes Pts/glucosa han mostrado ser ventajosos para aumentar la produccion de aminoácidos aromáticos.
MXPA/A/1997/008363A 1995-05-05 1997-10-30 Aplicacion de mutantes que transportan glucosa para la produccion de compuestos de la via aromatica MXPA97008363A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43551095A 1995-05-05 1995-05-05
US08/435,510 1995-05-05

Publications (2)

Publication Number Publication Date
MX9708363A true MX9708363A (es) 1998-06-30
MXPA97008363A MXPA97008363A (es) 1998-10-30

Family

ID=

Also Published As

Publication number Publication date
EP0827542B1 (en) 2008-04-09
EP1947186B1 (en) 2011-11-16
DE69637492T2 (de) 2009-06-04
DK0827542T3 (da) 2008-08-18
ATE391786T1 (de) 2008-04-15
US20020155521A1 (en) 2002-10-24
CA2220100A1 (en) 1996-11-07
ATE533848T1 (de) 2011-12-15
US6962794B2 (en) 2005-11-08
DK1947186T3 (da) 2012-02-06
EP1947186A2 (en) 2008-07-23
WO1996034961A1 (en) 1996-11-07
CA2220100C (en) 2009-03-17
US20050282257A1 (en) 2005-12-22
EP1947186A3 (en) 2008-11-05
DE69637492D1 (de) 2008-05-21
EP0827542A1 (en) 1998-03-11

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