MX9704726A - Vs ribozymes. - Google Patents

Vs ribozymes.

Info

Publication number
MX9704726A
MX9704726A MX9704726A MX9704726A MX9704726A MX 9704726 A MX9704726 A MX 9704726A MX 9704726 A MX9704726 A MX 9704726A MX 9704726 A MX9704726 A MX 9704726A MX 9704726 A MX9704726 A MX 9704726A
Authority
MX
Mexico
Prior art keywords
paired
ribozyme
percent
base
ribozymes
Prior art date
Application number
MX9704726A
Other languages
Spanish (es)
Other versions
MXPA97004726A (en
Inventor
Richard Collins
Original Assignee
Richard Collins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richard Collins filed Critical Richard Collins
Publication of MX9704726A publication Critical patent/MX9704726A/en
Publication of MXPA97004726A publication Critical patent/MXPA97004726A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Ribozyme able to cleave a separate substrate RNA molecule, said ribozyme having three base-paired regions generally, but not limited to, in a proposed "I" configuration, wherein "upper" and "lower" based-paired regions comprise between about 4 and 80 bases inclusive of which at least about 50 percent are paired with each other, and wherein the "connecting" region between said upper and lower base paired regions comprises between about 4 and 20 bases inclusive of which at least about 50 percent are paired.
MXPA/A/1997/004726A 1994-12-22 1997-06-23 Ribozimas varkud satell MXPA97004726A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36377494A 1994-12-22 1994-12-22
US363774 1994-12-22
PCT/IB1995/000141 WO1996019577A1 (en) 1994-12-22 1995-02-23 Vs ribozymes

Publications (2)

Publication Number Publication Date
MX9704726A true MX9704726A (en) 1997-10-31
MXPA97004726A MXPA97004726A (en) 1998-07-03

Family

ID=

Also Published As

Publication number Publication date
EP0795016A1 (en) 1997-09-17
CA2208097A1 (en) 1996-06-27
WO1996019577A1 (en) 1996-06-27
AU1716895A (en) 1996-07-10
JPH10510715A (en) 1998-10-20

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