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Priority claimed from ES09501965Aexternal-prioritypatent/ES2100129B1/en
Application filed by Medichem SafiledCriticalMedichem Sa
Publication of MX9704289ApublicationCriticalpatent/MX9704289A/en
Publication of MXPA97004289ApublicationCriticalpatent/MXPA97004289A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Novel polycylic aminopyridine compounds as inhibitors of acetylcholinesterase, process for their preparation and utilization thereof. The polycylic aminopyridine compounds have formula (I) wherein the various radicals have the meanings indicated in the description of the invention. The process for the preparation of said compounds is characterized in that ketones having general formula (II) are caused to react with aminonitriles having general formula (III), and, if necessary, the compounds of formula (I) are alkylated, aralkylated or acylated, or the corresponding ketonic precursor is reduced. The compounds having the general formula (I) are specially appropriate for the preparation of medicaments useful against memory troubles, such as senile dementia or the Alzheimer disease.
MXPA/A/1997/004289A1995-10-111997-06-10New polyinclinic aminopyridinic compounds inhibitors of acetilcolinesterase, procedure for its preparation and its use
MXPA97004289A
(en)