MX9704289A - Novel polycyclic aminopyridine compounds as acetylcholinesterase inhibitors, preparation process and use thereof. - Google Patents

Novel polycyclic aminopyridine compounds as acetylcholinesterase inhibitors, preparation process and use thereof.

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Publication number
MX9704289A
MX9704289A MX9704289A MX9704289A MX9704289A MX 9704289 A MX9704289 A MX 9704289A MX 9704289 A MX9704289 A MX 9704289A MX 9704289 A MX9704289 A MX 9704289A MX 9704289 A MX9704289 A MX 9704289A
Authority
MX
Mexico
Prior art keywords
compounds
preparation
preparation process
general formula
aminopyridine compounds
Prior art date
Application number
MX9704289A
Other languages
Spanish (es)
Other versions
MXPA97004289A (en
Inventor
Diego Munoz-Torre Lopez-Ibarra
Diana Marina Gorbig Romeu
Joan Contreras Lascorz
Monserrat Simon Fornell
Jordi Morral Cardoner
Rachid El Achab
Albert Badia Sancho
Josep Eladi Banos Diez
Nurai Maria Vivas
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES09501965A external-priority patent/ES2100129B1/en
Application filed by Medichem Sa filed Critical Medichem Sa
Publication of MX9704289A publication Critical patent/MX9704289A/en
Publication of MXPA97004289A publication Critical patent/MXPA97004289A/en

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Abstract

Novel polycylic aminopyridine compounds as inhibitors of acetylcholinesterase, process for their preparation and utilization thereof. The polycylic aminopyridine compounds have formula (I) wherein the various radicals have the meanings indicated in the description of the invention. The process for the preparation of said compounds is characterized in that ketones having general formula (II) are caused to react with aminonitriles having general formula (III), and, if necessary, the compounds of formula (I) are alkylated, aralkylated or acylated, or the corresponding ketonic precursor is reduced. The compounds having the general formula (I) are specially appropriate for the preparation of medicaments useful against memory troubles, such as senile dementia or the Alzheimer disease.
MXPA/A/1997/004289A 1995-10-11 1997-06-10 New polyinclinic aminopyridinic compounds inhibitors of acetilcolinesterase, procedure for its preparation and its use MXPA97004289A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES09501965A ES2100129B1 (en) 1995-10-11 1995-10-11 NEW POLYCLIC AMINOPYRIDINE COMPOUNDS ACETYLCHOLINESTERASE INHIBITORS, PROCEDURE FOR THE PREPARATION AND USE.
ES9501965 1995-10-11
PCT/ES1996/000192 WO1997013754A1 (en) 1995-10-11 1996-10-11 Novel polycyclic aminopyridine compounds as acetylcholinesterase inhibitors, preparation process and use thereof

Publications (2)

Publication Number Publication Date
MX9704289A true MX9704289A (en) 1997-09-30
MXPA97004289A MXPA97004289A (en) 1998-07-03

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