MX9604849A - Enlace de e-selectina, p-selectina o l-selectina con sialil-lewis (x) o sialil-lewis (a). - Google Patents

Enlace de e-selectina, p-selectina o l-selectina con sialil-lewis (x) o sialil-lewis (a).

Info

Publication number
MX9604849A
MX9604849A MX9604849A MX9604849A MX9604849A MX 9604849 A MX9604849 A MX 9604849A MX 9604849 A MX9604849 A MX 9604849A MX 9604849 A MX9604849 A MX 9604849A MX 9604849 A MX9604849 A MX 9604849A
Authority
MX
Mexico
Prior art keywords
selectin
sialyl
lewisx
binding
compounds
Prior art date
Application number
MX9604849A
Other languages
English (en)
Inventor
Timothy P Kogan
Brian Dupre
Ian L Scott
Karin Keller
Huong Dao
Pamela J Beck
Original Assignee
Texas Biotechnology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texas Biotechnology Corp filed Critical Texas Biotechnology Corp
Priority claimed from PCT/US1995/005463 external-priority patent/WO1995029682A1/en
Publication of MX9604849A publication Critical patent/MX9604849A/es

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La invencion se refiere a compuestos que tienen la estructura general (II) que inhibe el enlace de E-selectina y/o P-selectina sobre sialil-Lewis(x) o sialil-Lewis(a) presente sobre una superficie celular. Esta invencion se refiere también a métodos para inhibir el enlace de E-selectina y/o P-selectina sobre sialil-Lewis(x) o sialil-Lewis(a) presente sobre una superficie celular mediante el uso de dichos compuestos, y se refiere también a unas composiciones farmacéuticamente activas que comprenden compuestos que inhiben el enlace de E-selectina sobre sialil-Lewis(x). Esta invencion se refiere también a métodos para usar dichos compuestos para el tratamiento de choques sépticos, ARDS, síndrome de Crohn, enfermedad inflamatoria cronica como por ejemplo, psoriasis y artritis reumatoide, y daños por reperfusion que ocurren después de ataques al corazon, apoplejía y transplantes de organos.
MX9604849A 1995-04-28 1995-04-28 Enlace de e-selectina, p-selectina o l-selectina con sialil-lewis (x) o sialil-lewis (a). MX9604849A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/005463 WO1995029682A1 (en) 1994-04-29 1995-04-28 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWIS?a¿

Publications (1)

Publication Number Publication Date
MX9604849A true MX9604849A (es) 1998-02-28

Family

ID=39166705

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9604849A MX9604849A (es) 1995-04-28 1995-04-28 Enlace de e-selectina, p-selectina o l-selectina con sialil-lewis (x) o sialil-lewis (a).

Country Status (1)

Country Link
MX (1) MX9604849A (es)

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