MX9307996A - Derivados de oxima eter que tienen actividad inhibidora de lipoxigenasa. - Google Patents
Derivados de oxima eter que tienen actividad inhibidora de lipoxigenasa.Info
- Publication number
- MX9307996A MX9307996A MX9307996A MX9307996A MX9307996A MX 9307996 A MX9307996 A MX 9307996A MX 9307996 A MX9307996 A MX 9307996A MX 9307996 A MX9307996 A MX 9307996A MX 9307996 A MX9307996 A MX 9307996A
- Authority
- MX
- Mexico
- Prior art keywords
- oxima
- lipoxigenase
- eter
- derivatives
- inhibiting activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Esta invención se relaciona con compuestos que tienen actividad biológica para inhibir las enzimas lipoxigenasa, con composiciones farmacéuticas que comprenden estos compuestos y con un método médico de tratamiento. De manera más particular, esta invención se relaciona con ciertos compuestos de oxima éter sustituidos los cuales inhiben la biosíntesis de leucotrienos, con composiciones farmacéuticas que comprenden estos compuestos y con un método para inhibir la actividad de lipoxigenasa y biosíntesis de leucotrienos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/992,388 US5326883A (en) | 1992-12-18 | 1992-12-18 | Oxime ether derivatives having lipoxygenase inhibitory activity |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9307996A true MX9307996A (es) | 1994-08-31 |
Family
ID=25538283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9307996A MX9307996A (es) | 1992-12-18 | 1993-12-15 | Derivados de oxima eter que tienen actividad inhibidora de lipoxigenasa. |
Country Status (3)
Country | Link |
---|---|
US (1) | US5326883A (es) |
MX (1) | MX9307996A (es) |
WO (1) | WO1994014762A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5512581A (en) * | 1994-07-18 | 1996-04-30 | Abbott Laboratories | Iminoxycarboxylates and derivatives as inhibitors of leukotriene biosynthesis |
CA2205033C (en) * | 1994-11-10 | 2001-12-11 | Akiyoshi Kawai | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas as 5-lipoxygenase inhibitors |
CN1059669C (zh) * | 1994-11-10 | 2000-12-20 | 辉瑞大药厂 | 芳氧基环烯基-和芳氧基亚氨基环烯基羟基脲类化合物 |
US5795900A (en) * | 1995-10-03 | 1998-08-18 | Abbott Laboratories | Symmetrical bis-heteroaryl-methoxy-phenylalkyl carboxylates as inhibitors of leukotriene biosynthesis |
US5668146A (en) * | 1995-10-03 | 1997-09-16 | Abbott Laboratories | Symmetrical bis-heteroarylmethoxyphenyliminoxyalkyl carboxylates as inhibitors of leukotriene biosynthesis |
US5714488A (en) * | 1995-10-03 | 1998-02-03 | Abbott Laboratories | Bis-heteroarylylmethoxyphenyl ketone derivatives as inhibitors of leukotriene biosynthesis |
US5668150A (en) * | 1996-07-26 | 1997-09-16 | Abbott Laboratories | Non-symmetrical bis-heteroarylmethoxyphenylalkyl carboxylates as inhibitors of leukotriene biosynthesis |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4144245A (en) * | 1977-05-11 | 1979-03-13 | A. H. Robins Company, Inc. | 4-Hydroxymethyl-2-pyrrolidinones |
GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
ES2013834A6 (es) * | 1989-01-30 | 1990-06-01 | Uriach & Cia Sa J | Procedimiento para la obtencion de derivados 4-sustituidos de 2-alcoxitetrahidrofurano. |
DE4014987A1 (de) * | 1990-05-09 | 1991-11-14 | Basf Ag | Cyclohexenonoximether, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als herbizide |
US5169854A (en) * | 1992-02-26 | 1992-12-08 | Abbott Laboratories | N-substituted-furylalkenyl hydroxamic acid and N-hydroxyurea compounds having lipoxygenase inhibitory activity |
-
1992
- 1992-12-18 US US07/992,388 patent/US5326883A/en not_active Expired - Fee Related
-
1993
- 1993-12-14 WO PCT/US1993/012152 patent/WO1994014762A1/en active Application Filing
- 1993-12-15 MX MX9307996A patent/MX9307996A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US5326883A (en) | 1994-07-05 |
WO1994014762A1 (en) | 1994-07-07 |
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Legal Events
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FA | Abandonment or withdrawal |