MX9305965A - ACTIVE AGENT SUPPLY DEVICES, WITH A HIGHLY CONTROLLABLE PULSE EFFECT. - Google Patents

ACTIVE AGENT SUPPLY DEVICES, WITH A HIGHLY CONTROLLABLE PULSE EFFECT.

Info

Publication number
MX9305965A
MX9305965A MX9305965A MX9305965A MX9305965A MX 9305965 A MX9305965 A MX 9305965A MX 9305965 A MX9305965 A MX 9305965A MX 9305965 A MX9305965 A MX 9305965A MX 9305965 A MX9305965 A MX 9305965A
Authority
MX
Mexico
Prior art keywords
movement
capsule
arrow
partition
guide members
Prior art date
Application number
MX9305965A
Other languages
Spanish (es)
Inventor
Jeremy C Wright
Terry L Burkoth
James M Davenport
James B Eckenhoff
Sally A Tao
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of MX9305965A publication Critical patent/MX9305965A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Las cápsulas de suministro, que incluyen un agente benéfico y un mecanismo activador en departamentos separados por una división movible, están diseñadas através de una manera pulsátil, através de un orificio. Se logra el suministro pulsátil mediante un par de miembros de guía, dentro de la cápsula, uno de los cuales está asegurado a la propia cápsula y el otro a la división movible. Los miembros de guía, que pueden ser una flecha y un manguito, una flecha y un anillo, o alguna combinación similar de elementos, guían el movimiento de la división a lo largo del eje de la cápsula. El movimiento puede ser lineal o de rotación a la manera del tipo de tornillo, dependiendo de si la flecha está roscada o no. Se forma una serie de limitadores o retenes en los miembros de guía, y uno o más fiadores o miembros acopladores de retén, está formado en el otro miembro. Los fiadores comprueban el movimiento de la división y permiten que dicho movimiento ocurra por pulsos, a medida que aumenta la presión por encima de un nivel de umbral. El número y la separación de los retenes establece el número y la frecuencia de los pulsos, y la función pulsante opera independientemente del contacto sellador entre la división y la pared interna de la cápsula.The delivery capsules, which include a beneficial agent and an activating mechanism in departments separated by a movable partition, are designed through a pulsating way, through a hole. Pulsed delivery is accomplished by a pair of guide members, within the capsule, one of which is secured to the capsule itself and the other to the movable partition. The guide members, which may be an arrow and a sleeve, an arrow and a ring, or some similar combination of elements, guide the movement of the partition along the axis of the capsule. The movement can be linear or rotational in the manner of the screw type, depending on whether the arrow is threaded or not. A series of limiters or retainers is formed on the guide members, and one or more detent or catch coupler members is formed on the other member. The catches check the movement of the division and allow the movement to occur by pulses, as the pressure rises above a threshold level. The number and spacing of the retainers sets the number and frequency of the pulses, and the pulsing function operates independently of the sealing contact between the partition and the inner wall of the capsule.

MX9305965A 1992-09-29 1993-09-27 ACTIVE AGENT SUPPLY DEVICES, WITH A HIGHLY CONTROLLABLE PULSE EFFECT. MX9305965A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95454392A 1992-09-29 1992-09-29
PCT/US1993/009180 WO1994007562A1 (en) 1992-09-29 1993-09-27 Highly controllable pulsatile delivery device

Publications (1)

Publication Number Publication Date
MX9305965A true MX9305965A (en) 1994-04-29

Family

ID=25495582

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9305965A MX9305965A (en) 1992-09-29 1993-09-27 ACTIVE AGENT SUPPLY DEVICES, WITH A HIGHLY CONTROLLABLE PULSE EFFECT.

Country Status (5)

Country Link
AU (1) AU5292793A (en)
MX (1) MX9305965A (en)
TW (1) TW245642B (en)
WO (1) WO1994007562A1 (en)
ZA (1) ZA937146B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9610374B (en) * 1995-12-11 1997-06-23 Elan Med Tech Cartridge-based drug delivery device
US5875976A (en) * 1996-12-24 1999-03-02 Medi-Ject Corporation Locking mechanism for nozzle assembly
WO2003097118A2 (en) * 2002-05-15 2003-11-27 Aventis Pharma Deutschland Gmbh Adjusting element for an injection device
DE10300896A1 (en) * 2003-01-13 2004-07-22 Disetronic Licensing Ag Automatic delivery device driven by hydrogels with adjustable delivery characteristics to deliver a medium, especially insulin
US8491571B2 (en) 2003-06-12 2013-07-23 Cordis Corporation Orifice device having multiple channels with varying flow rates for drug delivery
US7211076B2 (en) 2003-06-12 2007-05-01 Cordis Corporation Medical device for fluid delivery having low fluid flow rate
US8109922B2 (en) 2003-06-12 2012-02-07 Cordis Corporation Orifice device having multiple channels and multiple layers for drug delivery
US7108762B2 (en) 2003-06-12 2006-09-19 Cordis Corporation Method for manufacturing an orifice mechanism capable of low fluid flow rates
US6976983B2 (en) 2003-06-12 2005-12-20 Cordis Corporation Implantable device for delivering drugs using orifice mechanism capable of low fluid flow rates
US7678103B2 (en) 2003-06-12 2010-03-16 Cordis Corporation Orifice device for delivering drugs at low fluid flow rates
EP1789128B1 (en) 2004-08-27 2018-05-09 STOCO 10 GmbH Electronically and remotely controlled pill and system for delivering at least one medicament
JP4755247B2 (en) * 2005-05-24 2011-08-24 テクファーマ・ライセンシング・アクチェンゲゼルシャフト Threaded rod for injection device and dosage setting mechanism
DE102005023854B4 (en) * 2005-05-24 2020-12-17 Tecpharma Licensing Ag Dosing device for an injection device
JP5500600B2 (en) 2008-06-19 2014-05-21 コーニンクレッカ フィリップス エヌ ヴェ Device for the delivery of powdered drugs in moist environments
TW201121601A (en) 2009-09-30 2011-07-01 Sanofi Aventis Deutschland Drive assembly, piston rod, drug delivery device, and use of a spring
US8939438B2 (en) 2010-01-08 2015-01-27 Lee Spring Company Llc Plastic spring and method and apparatus for making the same
US8535268B2 (en) 2010-12-22 2013-09-17 Alcon Research, Ltd. Device for at least one of injection or aspiration
FR3059890A1 (en) * 2016-12-12 2018-06-15 Virbac MULTI-DOSED DISPENSER

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601252B1 (en) * 1986-05-14 1990-06-08 Piani Jean MEDICATION INJECTION PUMP.
US4950163A (en) * 1988-05-19 1990-08-21 Zimble Alan W Dental syringe for treating gums
GB8829089D0 (en) * 1988-12-13 1989-01-25 Coopers Animal Health Intra ruminal device

Also Published As

Publication number Publication date
AU5292793A (en) 1994-04-26
ZA937146B (en) 1994-06-06
TW245642B (en) 1995-04-21
WO1994007562A1 (en) 1994-04-14

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