MX9304449A - CHEMICAL COMPOUNDS. - Google Patents

CHEMICAL COMPOUNDS.

Info

Publication number
MX9304449A
MX9304449A MX9304449A MX9304449A MX9304449A MX 9304449 A MX9304449 A MX 9304449A MX 9304449 A MX9304449 A MX 9304449A MX 9304449 A MX9304449 A MX 9304449A MX 9304449 A MX9304449 A MX 9304449A
Authority
MX
Mexico
Prior art keywords
antibody
compounds
chemical compounds
carboxypeptidase
present
Prior art date
Application number
MX9304449A
Other languages
Spanish (es)
Inventor
Anthony Mauger
Philip Burke
Robert Dowell
Caroline Joy Springer
Original Assignee
Zeneca Ltd
Cancer Research Campaign Techo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929215636A external-priority patent/GB9215636D0/en
Priority claimed from GB939310884A external-priority patent/GB9310884D0/en
Priority claimed from GB939314960A external-priority patent/GB9314960D0/en
Application filed by Zeneca Ltd, Cancer Research Campaign Techo filed Critical Zeneca Ltd
Publication of MX9304449A publication Critical patent/MX9304449A/en

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a compuestos que se usan en la terapia de prórrogas de enzima directas al anticuerpo ( ADEPT ), a los procedimientos para su preparación, a las composiciones farmacéuticas que las contienen, y a los métodos para su uso, así como a un sistema de dos componentes que comprende 1) un conjugado de una enzima y un anticuerpo o un fragmento del anticuerpo y 2) un compuesto de la presente invención. Los compuestos son particularmente de interés como las pro-drogas para usarse en conjunción con las enzimas de la carboxípeptidasa G, particularmente la carboxipeptidasa G2 (CPG2).The present invention relates to compounds that are used in the therapy of direct enzyme extensions to the antibody (ADEPT), to the procedures for their preparation, to the pharmaceutical compositions that contain them, and to the methods for their use, as well as to a two component system comprising 1) a conjugate of an enzyme and an antibody or a fragment of the antibody and 2) a compound of the present invention. The compounds are of particular interest as pro-drugs for use in conjunction with carboxypeptidase G enzymes, particularly carboxypeptidase G2 (CPG2).

MX9304449A 1992-07-23 1993-07-23 CHEMICAL COMPOUNDS. MX9304449A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929215636A GB9215636D0 (en) 1992-07-23 1992-07-23 Chemical compounds
GB939310884A GB9310884D0 (en) 1993-05-26 1993-05-26 Chemical compounds
GB939314960A GB9314960D0 (en) 1992-07-23 1993-07-21 Chemical compounds

Publications (1)

Publication Number Publication Date
MX9304449A true MX9304449A (en) 1994-05-31

Family

ID=27266299

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304449A MX9304449A (en) 1992-07-23 1993-07-23 CHEMICAL COMPOUNDS.

Country Status (1)

Country Link
MX (1) MX9304449A (en)

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees