MX9304187A - HEMATOPOYETIC FACILITATORY CELLS. - Google Patents

HEMATOPOYETIC FACILITATORY CELLS.

Info

Publication number
MX9304187A
MX9304187A MX9304187A MX9304187A MX9304187A MX 9304187 A MX9304187 A MX 9304187A MX 9304187 A MX9304187 A MX 9304187A MX 9304187 A MX9304187 A MX 9304187A MX 9304187 A MX9304187 A MX 9304187A
Authority
MX
Mexico
Prior art keywords
cells
hematopoietic
facilitator
bone marrow
present
Prior art date
Application number
MX9304187A
Other languages
Spanish (es)
Inventor
Sherry M Wren
Christina Kaufman
Suzanne T Ildstad
Richard L Simmons
Camillo Ricordi
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Publication of MX9304187A publication Critical patent/MX9304187A/en

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se relaciona con células facilitatorias hematopoyéticas de mamífero. En particular, se relaciona con el aislamiento, la caracterización y usos de las células facilitatorias hematopoyéticas. Las células facilitatorias de la presente invención se puede distinguir de las otras células de médula ósea conocidas mediante su morfología, fenotipo de superficie de célula y función in vivo. Cuando se co-administran con otras células de médula ósea incluyendo hemocitoblastos hematopoyéticos en un receptor, las células facilitatorias mejoran su injerto, sin actividades biológicas perjudiciales aparentes. Por lo tanto, las células facilitatorias pueden tener una amplia escala de aplicaciones, incluyendo, pero no quedando limitadas a reconstrucción hematopoyética mediante trasplante de médula ósea para el tratamiento de cánceres, anemias, autoinmunidad, inmunodeficiencia, infecciones virales y trastornos metabólicos, así como su uso potencial para facilitar el transplante de órgano sólido.The present invention relates to mammalian hematopoietic facilitator cells. In particular, it is related to the isolation, characterization and uses of hematopoietic facilitator cells. The facilitator cells of the present invention can be distinguished from other known bone marrow cells by their morphology, cell surface phenotype, and in vivo function. When co-administered with other bone marrow cells including hematopoietic hemocytoblasts in a receptor, the facilitating cells enhance their grafting, with no apparent detrimental biological activities. Therefore, facilitator cells can have a wide range of applications, including, but not limited to, hematopoietic reconstruction by bone marrow transplantation for the treatment of cancers, anemias, autoimmunity, immunodeficiency, viral infections, and metabolic disorders, as well as their potential use to facilitate solid organ transplantation.

MX9304187A 1992-07-10 1993-07-12 HEMATOPOYETIC FACILITATORY CELLS. MX9304187A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91198992A 1992-07-10 1992-07-10
US99654492A 1992-12-24 1992-12-24

Publications (1)

Publication Number Publication Date
MX9304187A true MX9304187A (en) 1994-02-28

Family

ID=27129590

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304187A MX9304187A (en) 1992-07-10 1993-07-12 HEMATOPOYETIC FACILITATORY CELLS.

Country Status (3)

Country Link
CN (1) CN1058991C (en)
IL (1) IL106295A (en)
MX (1) MX9304187A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006047954A1 (en) * 2004-11-04 2006-05-11 Ziyi Cheng The method of obtaining and applying the materials for autoantigen immunological recognition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell

Also Published As

Publication number Publication date
CN1091955A (en) 1994-09-14
IL106295A0 (en) 1993-11-15
CN1058991C (en) 2000-11-29
IL106295A (en) 2001-03-19

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