MX9303980A - NEW DERIVATIVES OF 10-DESACETILE BACCATIN III, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. - Google Patents

NEW DERIVATIVES OF 10-DESACETILE BACCATIN III, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.

Info

Publication number
MX9303980A
MX9303980A MX9303980A MX9303980A MX9303980A MX 9303980 A MX9303980 A MX 9303980A MX 9303980 A MX9303980 A MX 9303980A MX 9303980 A MX9303980 A MX 9303980A MX 9303980 A MX9303980 A MX 9303980A
Authority
MX
Mexico
Prior art keywords
preparation
pharmaceutical compositions
desacetile
procedure
contain
Prior art date
Application number
MX9303980A
Other languages
Spanish (es)
Inventor
Jean-Dominique Bourzat
Alain Commercon
Rodolphe Margraff
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of MX9303980A publication Critical patent/MX9303980A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se refiere a nuevos derivados del taxano de la fórmula general (I), a su preparación y a las composiciones framacéuticas que los contienen. En la fórmula general (I): Ar representa un radical arilo, R representa un radical fenilo o un radical R1-0- en el cual R1 representa un radical alquilo eventualmente sustituido, alquenilo, alquinilo, cicloalquilo, cicloalquenilo, bicicloalquilo, fenilo, heterociclico. Los nuevos productos de la fórmula general (I) presentan una actividad antitumorígena remarcable.This invention relates to new taxane derivatives of the general formula (I), their preparation and the pharmaceutical compositions containing them. In the general formula (I): Ar represents an aryl radical, R represents a phenyl radical or a R1-0- radical in which R1 represents an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl, heterocyclic radical . The new products of the general formula (I) have remarkable antitumorigenic activity.

MX9303980A 1992-07-03 1993-07-01 NEW DERIVATIVES OF 10-DESACETILE BACCATIN III, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. MX9303980A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR929208194A FR2693193B1 (en) 1992-07-03 1992-07-03 New derivatives of 10-deacetyl baccatin III, their preparation and the pharmaceutical compositions containing them.

Publications (1)

Publication Number Publication Date
MX9303980A true MX9303980A (en) 1994-01-31

Family

ID=9431481

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9303980A MX9303980A (en) 1992-07-03 1993-07-01 NEW DERIVATIVES OF 10-DESACETILE BACCATIN III, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.

Country Status (5)

Country Link
AU (1) AU4504893A (en)
FR (1) FR2693193B1 (en)
MX (1) MX9303980A (en)
WO (1) WO1994001425A1 (en)
ZA (1) ZA934741B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU693797B2 (en) * 1993-07-19 1998-07-09 Angiotech Pharmaceuticals, Inc. Anti-angiogenic compositions and methods of use
US20030203976A1 (en) 1993-07-19 2003-10-30 William L. Hunter Anti-angiogenic compositions and methods of use
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
CN110317183B (en) * 2019-08-08 2021-03-12 无锡紫杉药业有限公司 Method for purifying natural extract product of taxus chinensis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
FR2693193B1 (en) 1994-09-02
WO1994001425A1 (en) 1994-01-20
ZA934741B (en) 1994-01-24
FR2693193A1 (en) 1994-01-07
AU4504893A (en) 1994-01-31

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