MX9301458A - DERIVATIVES OF IMIDAZOPYRIDINE AND PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS THEM. - Google Patents

DERIVATIVES OF IMIDAZOPYRIDINE AND PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS THEM.

Info

Publication number
MX9301458A
MX9301458A MX9301458A MX9301458A MX9301458A MX 9301458 A MX9301458 A MX 9301458A MX 9301458 A MX9301458 A MX 9301458A MX 9301458 A MX9301458 A MX 9301458A MX 9301458 A MX9301458 A MX 9301458A
Authority
MX
Mexico
Prior art keywords
imidazopyridine
understands
derivatives
pharmaceutical composition
adjudicated
Prior art date
Application number
MX9301458A
Other languages
Spanish (es)
Inventor
Shoji Yasufuku
Asahiko Motonaga
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of MX9301458A publication Critical patent/MX9301458A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención se refiere a un derivado de imidazo[1,2-a]piridina de la siguiente fórmula general y su sal farmacológicamente aceptable. El compuesto de la invención no solamente es útil para controlar la inflamación, sino es valioso para el tratamiento de la artritis reumatoide, gracias a su actividad inhibitoria de la destrucción de la articulación, la cual no es adjudicada por las drogas antiinflamatorias conocidas.The invention relates to an imidazo [1,2-a] pyridine derivative of the following general formula and its pharmacologically acceptable salt. The compound of the invention is not only useful for controlling inflammation, but it is valuable for the treatment of rheumatoid arthritis, thanks to its joint destruction inhibitory activity, which is not adjudicated by known anti-inflammatory drugs.

MX9301458A 1992-03-17 1993-03-16 DERIVATIVES OF IMIDAZOPYRIDINE AND PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS THEM. MX9301458A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP9197192 1992-03-17
JP14623692 1992-05-12
JP18312892 1992-06-16

Publications (1)

Publication Number Publication Date
MX9301458A true MX9301458A (en) 1994-01-31

Family

ID=27306885

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9301458A MX9301458A (en) 1992-03-17 1993-03-16 DERIVATIVES OF IMIDAZOPYRIDINE AND PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS THEM.

Country Status (3)

Country Link
AU (1) AU3648993A (en)
MX (1) MX9301458A (en)
WO (1) WO1993019066A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4405378A1 (en) * 1994-02-19 1995-08-24 Merck Patent Gmbh Adhesion receptor antagonists
ES2140354B1 (en) * 1998-08-03 2000-11-01 S A L V A T Lab Sa IMIDAZO (1,2A) AZINAS SUBSTITUTED AS SELECTIVE INHIBITORS OF COX-2.
EP2444393A1 (en) 2003-02-19 2012-04-25 Eisai R&D Management Co., Ltd. Methods for producing cyclic benzamidine derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6355190A (en) * 1989-06-13 1991-01-17 Smithkline Beecham Corporation Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages

Also Published As

Publication number Publication date
WO1993019066A1 (en) 1993-09-30
AU3648993A (en) 1993-10-21

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