MX9207458A - PEPTIDE COMPOUNDS THAT HAVE THERAPEUTIC ACTIVITY. - Google Patents

PEPTIDE COMPOUNDS THAT HAVE THERAPEUTIC ACTIVITY.

Info

Publication number
MX9207458A
MX9207458A MX9207458A MX9207458A MX9207458A MX 9207458 A MX9207458 A MX 9207458A MX 9207458 A MX9207458 A MX 9207458A MX 9207458 A MX9207458 A MX 9207458A MX 9207458 A MX9207458 A MX 9207458A
Authority
MX
Mexico
Prior art keywords
therapeutic activity
peptide compounds
ahx
ile
phe
Prior art date
Application number
MX9207458A
Other languages
Spanish (es)
Inventor
James Donald Rosamond
Myles Edward Pierson
Original Assignee
Fisons Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929220543A external-priority patent/GB9220543D0/en
Priority claimed from GB929220761A external-priority patent/GB9220761D0/en
Application filed by Fisons Corp filed Critical Fisons Corp
Publication of MX9207458A publication Critical patent/MX9207458A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]
    • C07K14/5955—Gastrins; Cholecystokinins [CCK] at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Child & Adolescent Psychology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Los compuestos de la fórmula (I) en donde R1 es OH u OSO3H; M es Met, Ahx o Ile; G es Gly o Sar; X es Met, Ahx. Ile, Phe o LYs(R2); J es Asp, Asp (OBn), DAsp, MeAsp o MeDAsp; y L es Phe o MePhe, bajo diversas condiciones; y sus derivados farmacéuticamente aceptables, con útiles como agentes terapéuticos, en particular para la inhibición de alimentación.Compounds of formula (I) where R1 is OH or OSO3H; M is Met, Ahx or Ile; G is Gly or Sar; X is Met, Ahx. Ile, Phe or LYs (R2); J is Asp, Asp (OBn), DAsp, MeAsp or MeDAsp; and L is Phe or MePhe, under various conditions; and its pharmaceutically acceptable derivatives, with useful as therapeutic agents, in particular for feeding inhibition.

MX9207458A 1991-12-20 1992-12-18 PEPTIDE COMPOUNDS THAT HAVE THERAPEUTIC ACTIVITY. MX9207458A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81098591A 1991-12-20 1991-12-20
GB929220543A GB9220543D0 (en) 1992-09-29 1992-09-29 Pharmacologically active compounds
GB929220761A GB9220761D0 (en) 1992-10-02 1992-10-02 Pharmaceutically active compounds

Publications (1)

Publication Number Publication Date
MX9207458A true MX9207458A (en) 1993-11-01

Family

ID=27266393

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9207458A MX9207458A (en) 1991-12-20 1992-12-18 PEPTIDE COMPOUNDS THAT HAVE THERAPEUTIC ACTIVITY.

Country Status (11)

Country Link
EP (1) EP0619823A1 (en)
JP (1) JPH08500324A (en)
AU (1) AU672186B2 (en)
CA (1) CA2126236A1 (en)
FI (1) FI942898A0 (en)
HU (1) HU211564A9 (en)
IL (1) IL104161A0 (en)
MX (1) MX9207458A (en)
NO (1) NO942350L (en)
NZ (1) NZ246195A (en)
WO (1) WO1993013126A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754248R (en) * 1969-08-01 1971-02-01 Farmaceutici Italia ACTIVITY POLYPEPTIDES
NZ218607A (en) * 1985-12-19 1989-10-27 Pennwalt Corp Tri-to acta-peptides with sulphate ester groups: obesity treatment
IE873084L (en) * 1986-11-18 1988-05-18 Pfizer Hospital Prod Peptides with sulfate ester groups
WO1991008225A1 (en) * 1989-11-27 1991-06-13 Fisons Corporation Hexapeptides with sulphate ester groups

Also Published As

Publication number Publication date
AU3167893A (en) 1993-07-28
AU672186B2 (en) 1996-09-26
FI942898A (en) 1994-06-17
CA2126236A1 (en) 1993-07-08
FI942898A0 (en) 1994-06-17
JPH08500324A (en) 1996-01-16
EP0619823A1 (en) 1994-10-19
NO942350L (en) 1994-06-20
WO1993013126A1 (en) 1993-07-08
HU211564A9 (en) 1995-12-28
NO942350D0 (en) 1994-06-20
NZ246195A (en) 1995-11-27
IL104161A0 (en) 1993-05-13

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