MX9207162A - QUINOLINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. - Google Patents

QUINOLINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.

Info

Publication number
MX9207162A
MX9207162A MX9207162A MX9207162A MX9207162A MX 9207162 A MX9207162 A MX 9207162A MX 9207162 A MX9207162 A MX 9207162A MX 9207162 A MX9207162 A MX 9207162A MX 9207162 A MX9207162 A MX 9207162A
Authority
MX
Mexico
Prior art keywords
denotes
procedures
contain
preparation
pharmaceutical compositions
Prior art date
Application number
MX9207162A
Other languages
Spanish (es)
Inventor
Stefan Postius
George Rainer
Richard Riedel
Hartmann Schaefer
Jorg Senn-Bilfinger
Wolfgang-Alexander Simon
Robert John Ife
Colin Andrew Leach
Gerhard Grundler
Original Assignee
Smithkline Beecham Intercredit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Intercredit filed Critical Smithkline Beecham Intercredit
Publication of MX9207162A publication Critical patent/MX9207162A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

Compuestos de la fórmula (I) en donde R1 denota hidrógeno, hidroxilo (OH), halógeno o alquilo de C1-4 R2 denota hidrógeno o alquilo de C1-4, R3 denota alquilo de C1-4, A denota metileno (-CH2), etilo (-CH2CH2-), etilideno {-CH(CH3)-}, trimetileno (-CH2CH2CH2), oxietileno -O-CH2CH2- u oxitrimetileno (-O-CH2CH2CH''-), X denota alquileno de C1-6 o alquenileno de C2-4, y Y denota hidroxilo (OH) o amino (NH2) y sus sales, procedimientos para su preparación, su uso y los medicamentos que los contienen.Compounds of the formula (I) where R1 denotes hydrogen, hydroxyl (OH), halogen or C1-4alkyl R2 denotes hydrogen or C1-4alkyl, R3 denotes C1-4alkyl, A denotes methylene (-CH2) , ethyl (-CH2CH2-), ethylidene {-CH (CH3) -}, trimethylene (-CH2CH2CH2), oxyethylene -O-CH2CH2- or oxytrimethylene (-O-CH2CH2CH '-), X denotes C1-6 alkylene or C2-4 alkenylene, and Y denotes hydroxyl (OH) or amino (NH2) and its salts, procedures for their preparation, their use and the medicines that contain them.

MX9207162A 1991-12-12 1992-12-10 QUINOLINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. MX9207162A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919126438A GB9126438D0 (en) 1991-12-12 1991-12-12 New quinoline derivatives

Publications (1)

Publication Number Publication Date
MX9207162A true MX9207162A (en) 1994-08-31

Family

ID=10706172

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9207162A MX9207162A (en) 1991-12-12 1992-12-10 QUINOLINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.

Country Status (8)

Country Link
EP (1) EP0642500A1 (en)
JP (1) JPH07501812A (en)
AU (1) AU665223B2 (en)
CA (1) CA2125681A1 (en)
GB (1) GB9126438D0 (en)
MX (1) MX9207162A (en)
WO (1) WO1993012090A1 (en)
ZA (1) ZA929568B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS4164A (en) * 1993-06-11 1994-12-12 Ab Astra Compounds that inhibit gastric acid flow
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
UA80393C2 (en) 2000-12-07 2007-09-25 Алтана Фарма Аг Pharmaceutical preparation comprising an pde inhibitor dispersed on a matrix
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
MA22401A1 (en) * 1991-01-29 1992-10-01 Smithkline Beecham Intercredit PROCESS FOR THE PREPARATION OF GUINOLEIN SALTS

Also Published As

Publication number Publication date
EP0642500A1 (en) 1995-03-15
AU665223B2 (en) 1995-12-21
WO1993012090A1 (en) 1993-06-24
JPH07501812A (en) 1995-02-23
GB9126438D0 (en) 1992-02-12
AU3158593A (en) 1993-07-19
ZA929568B (en) 1994-06-10
CA2125681A1 (en) 1993-06-24

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