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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Abstract
La presente invención se refiere a heterociclos tricíclicos en donde X es oxi, tío, sulfinilo, sulfonilo, amino, alquilamino de 1-4C, o metileno, Y es carbonilo o metileno. A1 es alquileno, alquenileno o alquinileno Het es un grupo de heteroarilo de 5 o 6 miembros que tienen opcionalmente susbtituyentes particulares, G es carboxi, 1H-tetrazol-5-ilo o un grupo -CONHSO(2)R(2) y las sales farmaceuticamente aceptables del mismo, el cual tiene propiedades anti-hiperalgesicas. La invención también se refiere a un procedimiento para la obtención de heterociclos tricíclicos y a las composiciones farmacéutica novedosas que contienen a los mismos.The present invention relates to tricyclic heterocycles where X is oxy, uncle, sulfinyl, sulfonyl, amino, 1-4C-alkylamino, or methylene, Y is carbonyl or methylene. A1 is alkylene, alkenylene, or alkynylene Het is a 5- or 6-membered heteroaryl group optionally having particular substituents, G is carboxy, 1H-tetrazol-5-yl or a group -CONHSO (2) R (2) and the salts pharmaceutically acceptable thereof, which has anti-hyperalgesic properties. The invention also relates to a process for obtaining tricyclic heterocycles and to novel pharmaceutical compositions containing them.
POLYASPARTAMIDDERIVAT SOM ADSORPTIONSMEDEL FOER GALLSYRA, POLYASPARTAMIDDERIVAT INNEHAOLLANDE GALLSYROR OCH FOERFARANDE FOER FRAMSTAELLNING AV DESSA SAMT ANVAENDNING AV DESSA SOM LAEKEMEDEL
1,2,3,4-TETRAHYDROKINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, A PHARMACEUTICAL COMPOSITION AND THE USE IN THE PREPARATION OF A MEDICINAL PRODUCT