MX9204866A - SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS. - Google Patents
SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS.Info
- Publication number
- MX9204866A MX9204866A MX9204866A MX9204866A MX9204866A MX 9204866 A MX9204866 A MX 9204866A MX 9204866 A MX9204866 A MX 9204866A MX 9204866 A MX9204866 A MX 9204866A MX 9204866 A MX9204866 A MX 9204866A
- Authority
- MX
- Mexico
- Prior art keywords
- arylpolyamins
- antagonists
- synthetic
- amino acid
- acid neurotransmitters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/40—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74901491A | 1991-08-23 | 1991-08-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9204866A true MX9204866A (en) | 1993-04-01 |
Family
ID=25011863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9204866A MX9204866A (en) | 1991-08-23 | 1992-08-21 | SYNTHETIC ARYLPOLYAMINS AS ANTAGONISTS OF EXCITING AMINO ACID NEUROTRANSMITTERS. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0641312A1 (en) |
JP (1) | JPH06505996A (en) |
CN (1) | CN1069969A (en) |
AU (1) | AU2426392A (en) |
BR (1) | BR9206403A (en) |
CA (1) | CA2114798A1 (en) |
CZ (1) | CZ39994A3 (en) |
FI (1) | FI940833A0 (en) |
HU (1) | HU9400503D0 (en) |
IL (1) | IL102835A0 (en) |
MX (1) | MX9204866A (en) |
PT (1) | PT100801A (en) |
WO (1) | WO1993004036A1 (en) |
ZA (1) | ZA926314B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7087765B2 (en) | 1995-06-07 | 2006-08-08 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
US6211245B1 (en) | 1993-02-08 | 2001-04-03 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
US6071970A (en) * | 1993-02-08 | 2000-06-06 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
US6750244B2 (en) | 1993-02-08 | 2004-06-15 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
US6017965A (en) * | 1993-02-08 | 2000-01-25 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
CA2182680A1 (en) * | 1994-02-08 | 1995-08-17 | Alan L. Mueller | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
US20010004460A1 (en) * | 1995-06-08 | 2001-06-21 | Carla Rasmussen Klittich | Process for the preparation of rice seed for sowing |
AU2003231670B2 (en) * | 1997-10-27 | 2006-06-08 | Slil Biomedical Corporation | Methods for modulating macrophage proliferation using polyamine analogs |
US8198334B2 (en) | 1997-10-27 | 2012-06-12 | Pathologica Llc | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs |
US7087648B1 (en) * | 1997-10-27 | 2006-08-08 | The Regents Of The University Of California | Methods for modulating macrophage proliferation using polyamine analogs |
WO2003033455A1 (en) | 2001-10-16 | 2003-04-24 | Slil Biomedical Corporation | Oligoamine compounds and derivatives thereof for cancer therapy |
EP1667727B1 (en) * | 2003-09-09 | 2008-07-09 | University of Florida Research Foundation, Inc. | Polyamine-metal chelator conjugates |
CN103073448B (en) * | 2012-12-29 | 2015-11-18 | 河南大学 | Containing the polyamine derivative and its preparation method and application of aromatic ring structure |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5037846A (en) * | 1990-01-02 | 1991-08-06 | Pfizer Inc. | Indolyl-3 polyamines and their use as antagonists of excitatory amino acid neurotransmitters |
-
1992
- 1992-08-10 JP JP5504331A patent/JPH06505996A/en active Pending
- 1992-08-10 CZ CS94399A patent/CZ39994A3/en unknown
- 1992-08-10 AU AU24263/92A patent/AU2426392A/en not_active Abandoned
- 1992-08-10 WO PCT/US1992/006482 patent/WO1993004036A1/en not_active Application Discontinuation
- 1992-08-10 CA CA002114798A patent/CA2114798A1/en not_active Abandoned
- 1992-08-10 BR BR9206403A patent/BR9206403A/en not_active Application Discontinuation
- 1992-08-10 EP EP92916921A patent/EP0641312A1/en not_active Withdrawn
- 1992-08-10 HU HU9400503A patent/HU9400503D0/en unknown
- 1992-08-17 IL IL102835A patent/IL102835A0/en unknown
- 1992-08-21 MX MX9204866A patent/MX9204866A/en unknown
- 1992-08-21 PT PT100801A patent/PT100801A/en not_active Application Discontinuation
- 1992-08-21 ZA ZA926314A patent/ZA926314B/en unknown
- 1992-08-22 CN CN92109681A patent/CN1069969A/en active Pending
-
1994
- 1994-02-22 FI FI940833A patent/FI940833A0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL102835A0 (en) | 1993-01-31 |
JPH06505996A (en) | 1994-07-07 |
FI940833A (en) | 1994-02-22 |
CA2114798A1 (en) | 1993-03-04 |
CN1069969A (en) | 1993-03-17 |
HU9400503D0 (en) | 1994-05-30 |
EP0641312A1 (en) | 1995-03-08 |
WO1993004036A1 (en) | 1993-03-04 |
BR9206403A (en) | 1994-12-27 |
FI940833A0 (en) | 1994-02-22 |
CZ39994A3 (en) | 1994-11-16 |
PT100801A (en) | 1993-09-30 |
ZA926314B (en) | 1994-02-21 |
AU2426392A (en) | 1993-03-16 |
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