MX9101682A - COMPOUNDS EQUIVALENT TO LIVING SKIN. - Google Patents
COMPOUNDS EQUIVALENT TO LIVING SKIN.Info
- Publication number
- MX9101682A MX9101682A MX9101682A MX9101682A MX9101682A MX 9101682 A MX9101682 A MX 9101682A MX 9101682 A MX9101682 A MX 9101682A MX 9101682 A MX9101682 A MX 9101682A MX 9101682 A MX9101682 A MX 9101682A
- Authority
- MX
- Mexico
- Prior art keywords
- skin
- equivalent
- collagen
- layer
- well
- Prior art date
Links
Landscapes
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Abstract
se describe un compuesto equivalente a la piel viva que comprende una capa epidérmica de células cultivadas queratinociticas, una capa de colágeno no poroso, y una capa dérmica de células fibroblasticas cultivadas en una matriz de esponga de colágeno de enlace cruzado porosa. Preferentemente el colágeno no poroso es colágeno bovino del tipo 1, tipo 3 o mezcla de los tipos 1 y 3, el cual ha sido tratado con pepsina. Se describe un proceso para preparar el equivalente de piel, así como un equipo de prueba para la prueba in vitro del equivalente de la piel. El equivalente de piel tiene aplicación para injertos de piel así como para las pruebas in vitro de los efectos de varias substancias en la piel.We describe a compound equivalent to living skin comprising an epidermal layer of cultured keratinocytic cells, a layer of nonporous collagen, and a dermal layer of fibroblastic cells grown in a matrix of porous cross-link collagen sponge. Preferably the non-porous collagen is bovine collagen type 1, type 3 or mixture of types 1 and 3, which has been treated with pepsin. A process for preparing the skin equivalent is described, as well as a test kit for in vitro testing of the skin equivalent. The skin equivalent has application for skin grafts as well as for in vitro testing of the effects of various substances on the skin.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX9101682A MX9101682A (en) | 1991-10-21 | 1991-10-21 | COMPOUNDS EQUIVALENT TO LIVING SKIN. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX9101682A MX9101682A (en) | 1991-10-21 | 1991-10-21 | COMPOUNDS EQUIVALENT TO LIVING SKIN. |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9101682A true MX9101682A (en) | 1994-06-30 |
Family
ID=19743400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9101682A MX9101682A (en) | 1991-10-21 | 1991-10-21 | COMPOUNDS EQUIVALENT TO LIVING SKIN. |
Country Status (1)
Country | Link |
---|---|
MX (1) | MX9101682A (en) |
-
1991
- 1991-10-21 MX MX9101682A patent/MX9101682A/en unknown
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