MX377674B - Formulacion de tableta oral solida de rosuvastatina de liberacion inmediata y metformina de liberacion prolongada. - Google Patents
Formulacion de tableta oral solida de rosuvastatina de liberacion inmediata y metformina de liberacion prolongada.Info
- Publication number
- MX377674B MX377674B MX2014011167A MX2014011167A MX377674B MX 377674 B MX377674 B MX 377674B MX 2014011167 A MX2014011167 A MX 2014011167A MX 2014011167 A MX2014011167 A MX 2014011167A MX 377674 B MX377674 B MX 377674B
- Authority
- MX
- Mexico
- Prior art keywords
- release
- rosuvastatin
- metformin
- immediate
- extended
- Prior art date
Links
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003105 metformin Drugs 0.000 title abstract 4
- BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 title abstract 4
- 229960000672 rosuvastatin Drugs 0.000 title abstract 4
- 238000013265 extended release Methods 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000012729 immediate-release (IR) formulation Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 239000007935 oral tablet Substances 0.000 title 1
- 229940096978 oral tablet Drugs 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 239000007909 solid dosage form Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención está dirigida a un producto de dosificación sólida cuya formulación contenga una combinación fija de rosuvastatina y metformina, de tal manera que la rosuvastatina llegue inmediatamente al paciente y la metformina llegue de forma prolongada por un periodo de tiempo, también descrito como liberación prolongada, así como también a los métodos de hacer que tales formas de dosificación sólida y el uso de la forma de dosis de la invención en el tratamiento de pacientes con una combinación fija de formas de dosificación sólida de liberación inmediata de rosuvastatina y liberación prolongada de metformina.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261612563P | 2012-03-19 | 2012-03-19 | |
| US201261640971P | 2012-05-01 | 2012-05-01 | |
| PCT/US2013/031986 WO2013142314A1 (en) | 2012-03-19 | 2013-03-15 | Oral tablet formulation consisting of immediate release rosuv astatin and extended release metformin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014011167A MX2014011167A (es) | 2014-11-14 |
| MX377674B true MX377674B (es) | 2025-03-11 |
Family
ID=49223247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014011167A MX377674B (es) | 2012-03-19 | 2013-03-15 | Formulacion de tableta oral solida de rosuvastatina de liberacion inmediata y metformina de liberacion prolongada. |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2844067A4 (es) |
| MX (1) | MX377674B (es) |
| WO (1) | WO2013142314A1 (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030171407A1 (en) * | 2002-03-07 | 2003-09-11 | Upsher-Smith Laboratories, Inc. | Composition for reducing blood glucose and cholesterol |
| US7985422B2 (en) * | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
| EP1510208A1 (en) * | 2003-08-22 | 2005-03-02 | Fournier Laboratories Ireland Limited | Pharmaceutical composition comprising a combination of metformin and statin |
| CA2600736A1 (en) * | 2005-03-16 | 2006-09-21 | Dr. Reddy's Laboratories Ltd. | Delivery system for multiple drugs |
| EP1970053A1 (en) * | 2007-03-14 | 2008-09-17 | Boehringer Ingelheim Pharma GmbH & Co. KG | Pharmaceutical composition |
| WO2011049309A2 (ko) * | 2009-10-09 | 2011-04-28 | 영진약품공업 주식회사 | 속효성과 지속성을 동시에 갖는 약제학적 조성물 |
| JP5662475B2 (ja) * | 2009-12-30 | 2015-01-28 | ビーシーワールド ファーム. カンパニー リミテッド | メトホルミン及びロスバスチンを含む医薬組成物 |
-
2013
- 2013-03-15 EP EP13765204.6A patent/EP2844067A4/en not_active Withdrawn
- 2013-03-15 WO PCT/US2013/031986 patent/WO2013142314A1/en not_active Ceased
- 2013-03-15 MX MX2014011167A patent/MX377674B/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| MX2014011167A (es) | 2014-11-14 |
| EP2844067A1 (en) | 2015-03-11 |
| WO2013142314A1 (en) | 2013-09-26 |
| EP2844067A4 (en) | 2015-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |