MX358162B - Dispositivos y metodos para detectar celulas y otros analizados. - Google Patents
Dispositivos y metodos para detectar celulas y otros analizados.Info
- Publication number
- MX358162B MX358162B MX2012013429A MX2012013429A MX358162B MX 358162 B MX358162 B MX 358162B MX 2012013429 A MX2012013429 A MX 2012013429A MX 2012013429 A MX2012013429 A MX 2012013429A MX 358162 B MX358162 B MX 358162B
- Authority
- MX
- Mexico
- Prior art keywords
- analytes
- devices
- methods
- analyte
- detecting cells
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000012491 analyte Substances 0.000 abstract 4
- 238000002955 isolation Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La presente invención se refiere a métodos, dispositivos, y kits para el aislamiento de analizados (v.gr., una célula). Una muestra conteniendo un analizado deseado se introduce dentro de un dispositivo microfluídico conteniendo fracciones que se ligan al analizado deseado. Un esfuerzo cortante se aplica que es suficientemente grande para prevenir ligadura de analizados no deseados y suficientemente baja para permitir ligadura del analizado de interés. Una vez ligados, los analizados deseados pueden analizarse (v.gr., contarse). La invención también presenta métodos para determinar un esfuerzo cortante para aislar un analizado deseado.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78247006P | 2006-03-15 | 2006-03-15 | |
| PCT/US2007/006791 WO2007106598A2 (en) | 2006-03-15 | 2007-03-15 | Devices and methods for detecting cells and other analytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX358162B true MX358162B (es) | 2018-08-06 |
Family
ID=38510118
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008011787A MX2008011787A (es) | 2006-03-15 | 2007-03-15 | Dispositivos y metodos para detectar celulas y otros analizados. |
| MX2012013429A MX358162B (es) | 2006-03-15 | 2007-03-15 | Dispositivos y metodos para detectar celulas y otros analizados. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008011787A MX2008011787A (es) | 2006-03-15 | 2007-03-15 | Dispositivos y metodos para detectar celulas y otros analizados. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8911957B2 (es) |
| EP (1) | EP2002262B1 (es) |
| CN (1) | CN101443660B (es) |
| AP (1) | AP2954A (es) |
| AU (1) | AU2007225057B2 (es) |
| BR (1) | BRPI0709600A2 (es) |
| CA (1) | CA2646293C (es) |
| IL (1) | IL194101A (es) |
| MX (2) | MX2008011787A (es) |
| MY (1) | MY146468A (es) |
| WO (1) | WO2007106598A2 (es) |
| ZA (1) | ZA200808029B (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140008210A1 (en) * | 2012-07-06 | 2014-01-09 | Aviva Biosciences Corporation | Methods and compositions for separating or enriching cells |
| KR100844350B1 (ko) * | 2007-01-09 | 2008-07-07 | 주식회사 디지탈바이오테크놀러지 | 부유 혼합 미세입자 중 특정 미세입자를 광학적인 방법으로계수하기 위한 미세채널 칩 및 이를 이용한 미세입자 계수방법 |
| EP2350652A2 (en) | 2008-10-10 | 2011-08-03 | Cnrs-Dae | Cell sorting device |
| DE102008053270A1 (de) | 2008-10-27 | 2010-05-12 | Medizinische Hochschule Hannover | Vorrichtung und Verfahren zur Analyse von Zellen |
| US8242792B2 (en) | 2008-10-30 | 2012-08-14 | Bose Corporation | Impedance measurement system and method |
| WO2010080978A2 (en) * | 2009-01-08 | 2010-07-15 | The General Hospital Corporation | Pre-depletion of leukocytes in whole blood samples prior to the capture of whole blood sample components |
| US20120045827A1 (en) * | 2009-03-09 | 2012-02-23 | Biofactura, Inc. | Separation of antigen-specific memory b cells with a conjugated biopolymer surface |
| JP5759443B2 (ja) * | 2009-03-18 | 2015-08-05 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 循環細胞の捕獲用デバイス |
| WO2011063324A2 (en) * | 2009-11-20 | 2011-05-26 | The General Hospital Corporation | Microfluidic systems for isolating microvesicles |
| WO2011098509A1 (en) * | 2010-02-11 | 2011-08-18 | Katholieke Universiteit Leuven | Phospholipid profiling and cancer |
| CN102533933A (zh) * | 2010-12-15 | 2012-07-04 | 潘申权 | 用于检测口腔炎症指数的方法和试剂、试剂盒及其应用 |
| WO2011097962A1 (zh) * | 2010-02-12 | 2011-08-18 | Pan Shenquan | 检测和清除口炎斑和口炎结的方法和工具 |
| CN103119441A (zh) * | 2010-08-15 | 2013-05-22 | Gpb科学有限责任公司 | 血液分析中的微流体细胞分离 |
| GB201016139D0 (en) * | 2010-09-24 | 2010-11-10 | Univ Leuven Kath | Cancer phosholipidome |
| BR112013011451A2 (pt) * | 2010-11-09 | 2016-08-09 | Massachusetts Inst Technology | contagem de partículas usando um contador diferencial elétrico |
| US9063118B2 (en) | 2011-03-24 | 2015-06-23 | University Of Iowa Research Foundation | Isolation and characterization of tumor cells using shear stress measurements |
| US9541480B2 (en) | 2011-06-29 | 2017-01-10 | Academia Sinica | Capture, purification, and release of biological substances using a surface coating |
| WO2013013245A2 (en) * | 2011-07-21 | 2013-01-24 | The Regents Of The University Of California | Catalytic delivery nanoubstrates (cdns) for highly efficient delivery of biomolecules |
| US20130302884A1 (en) * | 2012-02-29 | 2013-11-14 | Fluidigm Corporation | Methods, systems and devices for multiple single-cell capturing and processing using microfluidics |
| US9518914B2 (en) * | 2012-09-24 | 2016-12-13 | Brigham And Women's Hospital, Inc. | Portal and method for management of dialysis therapy |
| US10551376B2 (en) | 2013-02-01 | 2020-02-04 | The General Hospital Corporation | Capture and release of particles from liquid samples |
| US20140275292A1 (en) * | 2013-03-14 | 2014-09-18 | William Michael Schopperle | Systems and methods employing human stem cell markers for detection, diagnosis and treatment of circulating tumor cells |
| US20160091489A1 (en) * | 2013-06-03 | 2016-03-31 | University Of Florida Research Foundation, Incorporated | Devices and methods for isolating cells |
| CN103323383B (zh) * | 2013-06-03 | 2015-03-11 | 北京理工大学 | 一种基于电阻抗技术的微流控芯片微粒计数系统 |
| CN115595240A (zh) * | 2013-11-20 | 2023-01-13 | 布里格姆女子医院有限公司(Us) | 用于精子分选的系统和方法 |
| CN105980058A (zh) | 2014-01-07 | 2016-09-28 | 达克雷诊断器材有限公司 | 流体输送装置、系统和方法 |
| TW201623605A (zh) | 2014-04-01 | 2016-07-01 | 中央研究院 | 用於癌症診斷及預後之方法及系統 |
| CN103977468B (zh) * | 2014-05-26 | 2016-05-18 | 国家纳米科学中心 | 用于分离去除血液中循环肿瘤细胞和血小板的系统及方法 |
| EP3149482A1 (de) * | 2014-05-29 | 2017-04-05 | ABA GmbH & Co. KG | Diagnose von krebserkrankungen |
| US10391491B2 (en) | 2014-08-07 | 2019-08-27 | The General Hospital Corporation | Platelet-targeted microfluidic isolation of cells |
| CN105381824B (zh) | 2014-08-26 | 2019-04-23 | 中央研究院 | 收集器架构布局设计 |
| JP2016080563A (ja) * | 2014-10-20 | 2016-05-16 | 日本光電工業株式会社 | 分析システム、分析装置 |
| EP3212766B1 (en) * | 2014-10-31 | 2019-12-04 | University of Iowa Research Foundation | Fluid handling systems for application of fluid shear stress to a fluid sample |
| EP3056565A1 (en) * | 2015-02-13 | 2016-08-17 | Karlsruher Institut für Technologie | Immobilization of cells or virus particles on protein structures using a microfluidic chamber |
| HK1250778A1 (zh) * | 2015-04-28 | 2019-01-11 | 奥菲迪亚有限公司 | 分析物检测及其方法 |
| US20190011349A1 (en) * | 2016-01-12 | 2019-01-10 | The Board Of Trustees Of The University Of Illinois | Label-free characterization of particles suspended in a fluid |
| US10107726B2 (en) | 2016-03-16 | 2018-10-23 | Cellmax, Ltd. | Collection of suspended cells using a transferable membrane |
| US20210140941A1 (en) * | 2017-03-16 | 2021-05-13 | Case Western Reserve University | Biochip having microchannel provided with capturing agent for performing cytological analysis |
| US12297417B2 (en) | 2018-08-21 | 2025-05-13 | University Of Florida Research Foundation, Incorporated | Lateral filter array microfluidic device |
| EP3963333A4 (en) * | 2019-05-03 | 2023-07-19 | Versitech Limited | Method for peritoneal metastatic cell detection and isolation thereof |
| EP4051775A4 (en) * | 2019-10-30 | 2024-02-28 | Case Western Reserve University | BIOCHIP WITH MICROCHANNEL WITH RECEPTION AGENT FOR PERFORMING CYTOLOGICAL ANALYSIS |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5215926A (en) * | 1988-06-03 | 1993-06-01 | Cellpro, Inc. | Procedure for designing efficient affinity cell separation processes |
| US6251615B1 (en) * | 1998-02-20 | 2001-06-26 | Cell Analytics, Inc. | Cell analysis methods |
| US20030190368A1 (en) * | 1998-03-11 | 2003-10-09 | Roland Stoughton | Methods of diagnosis and triage using cell activation measures |
| US20020006664A1 (en) * | 1999-09-17 | 2002-01-17 | Sabatini David M. | Arrayed transfection method and uses related thereto |
| US20060073095A1 (en) * | 2001-08-22 | 2006-04-06 | Steven Kessler | Methods for screening antibody-producing cells on heterogeneous antigen substrates |
| WO2003044481A2 (en) | 2001-11-20 | 2003-05-30 | Burstein Technologies, Inc. | Optical bio-discs and microfluidic devices for analysis of cells |
| AU2003256329A1 (en) * | 2002-06-27 | 2004-01-19 | University Of Washington | Use of adhesion molecules as bond stress-enhanced nanoscale binding switches |
| ES2375724T3 (es) * | 2002-09-27 | 2012-03-05 | The General Hospital Corporation | Dispositivo microflu�?dico para seperación de células y sus usos. |
| US20040132642A1 (en) * | 2002-11-12 | 2004-07-08 | Government Of The U.S.A., Represented By The Secretary, Dept. Of Health & Human Services | Methods of inhibiting metastasis or growth of a tumor cell |
| US20060223195A1 (en) * | 2004-11-16 | 2006-10-05 | Meyer Grant D | Stress based removal of nonspecific binding from surfaces |
| US20060183223A1 (en) * | 2005-01-21 | 2006-08-17 | King Michael R | Continuous flow chamber device for separation, concentration, and/or purification of cells |
| US8541227B2 (en) * | 2005-02-25 | 2013-09-24 | Dako Denmark A/S | Cell counting |
-
2007
- 2007-03-15 CN CN2007800173969A patent/CN101443660B/zh not_active Expired - Fee Related
- 2007-03-15 AP AP2008004636A patent/AP2954A/xx active
- 2007-03-15 US US12/293,046 patent/US8911957B2/en not_active Expired - Fee Related
- 2007-03-15 EP EP07753420.4A patent/EP2002262B1/en not_active Not-in-force
- 2007-03-15 CA CA2646293A patent/CA2646293C/en not_active Expired - Fee Related
- 2007-03-15 MX MX2008011787A patent/MX2008011787A/es unknown
- 2007-03-15 MY MYPI20083583A patent/MY146468A/en unknown
- 2007-03-15 WO PCT/US2007/006791 patent/WO2007106598A2/en not_active Ceased
- 2007-03-15 MX MX2012013429A patent/MX358162B/es unknown
- 2007-03-15 BR BRPI0709600-3A patent/BRPI0709600A2/pt not_active Application Discontinuation
- 2007-03-15 AU AU2007225057A patent/AU2007225057B2/en not_active Ceased
-
2008
- 2008-09-15 IL IL194101A patent/IL194101A/en not_active IP Right Cessation
- 2008-09-18 ZA ZA2008/08029A patent/ZA200808029B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007106598A2 (en) | 2007-09-20 |
| EP2002262A2 (en) | 2008-12-17 |
| EP2002262A4 (en) | 2010-03-24 |
| BRPI0709600A2 (pt) | 2011-07-19 |
| AP2008004636A0 (en) | 2008-10-31 |
| WO2007106598A3 (en) | 2008-11-13 |
| US20090298067A1 (en) | 2009-12-03 |
| AU2007225057A1 (en) | 2007-09-20 |
| MY146468A (en) | 2012-08-15 |
| CN101443660B (zh) | 2013-11-20 |
| ZA200808029B (en) | 2011-12-28 |
| MX2008011787A (es) | 2008-12-01 |
| CA2646293C (en) | 2015-08-25 |
| CN101443660A (zh) | 2009-05-27 |
| US8911957B2 (en) | 2014-12-16 |
| EP2002262B1 (en) | 2016-06-22 |
| AU2007225057B2 (en) | 2013-08-29 |
| IL194101A (en) | 2012-10-31 |
| CA2646293A1 (en) | 2007-09-20 |
| AP2954A (en) | 2014-08-31 |
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